凋亡
基因
试剂
文献样例
产品评述样例
ACIN1
apoptotic chromatin condensation inducer 1
ADD1
adducin 1 (alpha)
Akt
v-akt murine thymoma viral oncogene homolog 1
总数:418
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. 2011 至该文献
为了研究泡状H+-ATPase参与到mTOR通路中mTORC1的转位和激活，采用Cell Signaling的抗Akt和抗S473磷酸化Akt抗体进行蛋白印迹实验。 更多
Apaf-1
apoptotic peptidase activating factor 1
总数:9
Role for X-linked Inhibitor of apoptosis protein upstream of mitochondrial permeabilization. 2010 至该文献
为了研究XIAP在调控线粒体通透性中的作用，采用了Bioquote公司的单克隆抗Apaf-1抗体产品，进行了免疫印迹实验。 更多
APC
adenomatous polyposis coli
总数:11
A cell motility screen reveals role for MARCKS-related protein in adherens junction formation and tumorigenesis. 2009 至该文献
为了研究MRP蛋白在粘着连接形成和肿瘤发生过程中起重要作用，采用Calbiochem的APC抗体进行免疫细胞化学实验。 更多
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGAP10
Rho GTPase activating protein 10
BAD
BCL2-associated agonist of cell death
总数:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 至该文献
为了研究切割的NIK 导致非经典的NF- kB 活性，采用了Cell Signaling Technology的抗BAD抗体进行免疫印迹试验。 更多
Bak
BCL2-antagonist/killer 1
总数:26
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. 2011 至该文献
为了研究化疗对线粒体激发高的病人有着良好的治疗效果，采用Upstate的抗BAK抗体进行蛋白印迹实验。 更多
B细胞淋巴瘤2相关的X蛋白 (Bax)
BCL2-associated X protein
总数:102
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. 2011 至该文献
为了研究化疗对线粒体激发高的病人有着良好的治疗效果，采用Santa Cruz的抗BAX抗体进行蛋白印迹实验。 更多
BCAP31
B-cell receptor-associated protein 31
总数:1
Endoplasmic reticulum membrane-sorting protein of lymphocytes (BAP31) is highly expressed in neurons and discrete endocrine cells. 2001 至该文献
Bcl 2
B-cell CLL/lymphoma 2
总数:128
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. 2011 至该文献
为了研究去氢表雄酮和神经生长因子受体之间的相互作用，采用了Santa Cruz公司的抗Bcl-2抗体(C-2, sc-7382,1:500)进行了免疫印记实验。 更多
Bcl-xL
BCL2-like 1
总数:83
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. 2011 至该文献
为了研究化疗对线粒体激发高的病人有着良好的治疗效果，采用Cell Signaling的抗BCL-Xl抗体进行蛋白印迹实验。 更多
beta 连环蛋白 (beta-catenin)
catenin (cadherin-associated protein), beta 1, 88kDa
总数:151
A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network. 2010 至该文献
为了研究果蝇p53和人类p53网络之间的关系，采用Santa Cruz鼠抗UBF1抗体进行免疫细胞化学实验。 更多
Bid
BH3 interacting domain death agonist
总数:35
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. 2011 至该文献
为了研究化疗对线粒体激发高的病人有着良好的治疗效果，采用Santa Cruz的抗Bid抗体进行蛋白印迹实验。 更多
Bim
BCL2-like 11 (apoptosis facilitator)
总数:29
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. 2011 至该文献
为了研究化疗对线粒体激发高的病人有着良好的治疗效果，采用Cell Signaling的抗BIM抗体进行蛋白印迹实验。 更多
BMF
Bcl2 modifying factor
总数:1
Bim and Bmf synergize to induce apoptosis in Neisseria gonorrhoeae infection. 2009 至该文献
为了研究Bim和Bmf蛋白对感染了淋病奈瑟氏菌细胞的作用，使用了Cell Signaling公司的Bmf抗体来进行蛋白印迹实验。
BMX
BMX non-receptor tyrosine kinase
总数:2
Chemotactic factor-induced recruitment and activation of Tec family kinases in human neutrophils. Implication of phosphatidynositol 3-kinases. 2002 至该文献
c-IAP1
baculoviral IAP repeat containing 2
总数:15
Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination. 2011 至该文献
为了利用cIAP1的自身泛素化能够被拮抗剂诱导的cIAP1的构象改变所促进，采用Alexis的抗cIAP1抗体进行蛋白印迹实验。 更多
caspase-10
caspase 10, apoptosis-related cysteine peptidase
总数:9
The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production. 2006 至该文献
caspase-3
caspase 3, apoptosis-related cysteine peptidase
总数:209
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 至该文献
为了研究myc依赖的癌症需要SUMO化修饰来促进肿瘤发生，采用Cell Signaling的抗Cleaved caspase-3抗体进行蛋白印迹实验。 更多
Caspase-6
caspase 6, apoptosis-related cysteine peptidase
总数:12
Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6. 2010 至该文献
为了研究DJ-1基因突变在调节帕金森综合症中的作用，采用了Abcam公司的单克隆抗caspase-6抗体产品，进行了免疫印迹实验 更多
caspase-7
caspase 7, apoptosis-related cysteine peptidase
总数:23
NKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease. 2010 至该文献
为了说明多个依赖于CD3 Zeta的受体可以同时因病变的NKG2D配体表达而损伤，使用了Cell Signaling Technology公司的抗caspase-7抗体进行蛋白印迹实验。 更多
caspase-8
caspase 8, apoptosis-related cysteine peptidase
总数:73
Detachment of esophageal carcinoma cells from extracellular matrix causes relocalization of death receptor 5 and apoptosis. 2009 至该文献
为了研究在EC9706细胞从黏附到脱离过程中DR5的重定位机制以及其对细胞凋亡的影响，使用了R&D systems公司的抗casp8抗体来进行免疫印迹分析。 更多
Caspase-9
caspase 9, apoptosis-related cysteine peptidase
总数:74
Costunolide-induced apoptosis is caused by receptor-mediated pathway and inhibition of telomerase activity in NALM-6 cells. 2008 至该文献
为了表明木香烃内酯(costunolide)对NALM-6细胞的处理对凋亡相关蛋白表达的影响，采用了Cell Signaling Technology公司的caspase-9抗体进行蛋白免疫印迹实验。 更多
CLSPN
claspin
总数:6
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 至该文献
为了研究FANCM在有丝分裂过程中的降解机制，使用了Bethyl Laboratories的兔抗Claspin抗体来进行免疫印迹分析。 更多
CYCS
cytochrome c, somatic
总数:47
Prostate cancer antigen-1 contributes to cell survival and invasion though discoidin receptor 1 in human prostate cancer. 2008 至该文献
为研究人前列腺癌中PCA-1对细胞存活和DDR1信号通路的作用，采用了Cell Signaling公司的抗cytochrome c抗体进行免疫印迹、免疫沉淀和免疫组化试验。 更多
DAPK1
death-associated protein kinase 1
总数:2
A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK. 2002 至该文献
DAPK2
death-associated protein kinase 2
DBNL
drebrin-like
DCC
deleted in colorectal carcinoma
总数:2
Netrin-1 inhibits leukocyte migration in vitro and in vivo. 2005 至该文献
desmoplakin
总数:11
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. 2008 至该文献
为了研究四旋蛋白TM4SF5在接触抑制和肿瘤发生中的作用，采用Serotec公司的抗desmoplakin抗体进行免疫印迹实验。 更多
DFF45
DNA fragmentation factor, 45kDa, alpha polypeptide
总数:8
Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis. 2007 至该文献
DFFB
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
总数:3
Oligomerization state of the DNA fragmentation factor in normal and apoptotic cells. 2005 至该文献
DNM1L
dynamin 1-like
总数:4
ER tubules mark sites of mitochondrial division. 2011 至该文献
为了研究线粒体裂变受内质网小管的调控，采用Abcam的抗Dnm1L抗体进行蛋白印迹实验。 更多
DR5
tumor necrosis factor receptor superfamily, member 10b
总数:15
The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease. 2010 至该文献
为了研究Fas配体和TRAIL在调控鼠胸腺移植物抗宿主病中的作用，采用了eBioscience公司的抗DR5抗体产品，进行了流式细胞分析实验。 更多
Dsg1
desmoglein 1
总数:6
The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes. 2006 至该文献
DSG2
desmoglein 2
dsg3
desmoglein 3
总数:4
Limbal epithelial crypt: a model for corneal epithelial maintenance and novel limbal regional variations. 2008 至该文献
为了细胞膜蛋白和细胞外基质蛋白在角巩膜缘的分布，采用了Zymed Laboratories的抗desmoglein 3抗体进行免疫组化实验。 更多
DYNLL1
dynein, light chain, LC8-type 1
总数:3
Requirement for Nudel and dynein for assembly of the lamin B spindle matrix. 2009 至该文献
为研究nudel 和dynein在核纤层蛋白B纺锤体基质的组装中的作用，将Abcam提供的单克隆抗dynein抗体（74.1，ab23905）用于阻断或激活实验中。 更多
DYNLL2
dynein, light chain, LC8-type 2
E钙粘蛋白 (E-cadherin)
cadherin 1, type 1, E-cadherin (epithelial)
总数:127
Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma. 2010 至该文献
为了研究在食道鳞状细胞癌中尿溶蛋白1A（UPK1A）的作用，采用了Santa Cruz Biotechnology公司的抗E-cadherin的抗体进行蛋白免疫印迹实验。 更多
FADD
Fas (TNFRSF6)-associated via death domain
总数:19
Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis. 2008 至该文献
为了评价Ginsenoside Rk1蛋白对细胞和端粒酶活性的影响，使用了Cell Signaling Technology公司的抗FADD抗体来进行蛋白印迹实验。 更多
FAK
PTK2 protein tyrosine kinase 2
总数:99
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 至该文献
为了研究c-Src激酶是否会促使非典型小叶增生或小叶原位癌转变为浸润性小叶癌，使用了Santa Cruz Biotechnology公司的抗Fak抗体(1:1000)进行免疫荧光实验。 更多
肿瘤坏死因子受体超家族成员6 (Fas)
Fas (TNF receptor superfamily, member 6)
总数:52
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 至该文献
为了说明YB-1、GST、ABCB5和ERK3能够成为乳腺癌细胞耐药性治疗的潜在靶点，使用了Santa Cruz Biotechnology公司的FAS抗体(1:500)来进行免疫印记实验。 更多
FasL
Fas ligand (TNF superfamily, member 6)
总数:12
HYAL1-v1, an alternatively spliced variant of HYAL1 hyaluronidase: a negative regulator of bladder cancer. 2006 至该文献
FNTA
farnesyltransferase, CAAX box, alpha
gankyrin
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
GAS2
growth arrest-specific 2
总数:1
The calpain system is involved in the constitutive regulation of beta-catenin signaling functions. 2005 至该文献
凝溶胶蛋白 (gelsolin)
总数:8
Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. 2007 至该文献
为了研究海拉细胞中/-CaD与内皮细胞和内皮祖细胞的迁移之间的联系，使用了西格玛公司的抗凝溶胶蛋白抗体来进行免疫组化分析。 更多
granzyme B
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
总数:4
Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. 2009 至该文献
为了研究IL-33促进过敏炎症的机制，使用了Santa Cruz Biotechnology公司的小鼠抗granzyme B单克隆抗体来进行免疫荧光实验。 更多
H1F0
H1 histone family, member 0
总数:3
DNA-binding and -bending activities of SAP30L and SAP30 are mediated by a zinc-dependent module and monophosphoinositides. 2009 至该文献
为了阐明SAP30L和SAP30在调节染色体重组和转录过程中关键蛋白与蛋白、蛋白与DNA相互作用中的新功能，使用了Santa Cruz 公司的抗histone H1抗体进行免疫印迹。 更多
HIST1H1A
histone cluster 1, H1a
总数:2
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 至该文献
为了研究UV引起的DNA损伤及应激反应，采用了Abcam histone H1抗体进行了蛋白质印迹实验。 更多
HIST1H1B
histone cluster 1, H1b
总数:1
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. 2009 至该文献
为说明G9a/KMT1C和jumonji-C型组蛋白甲基化酶对组蛋白的甲基化、去甲基化所起的作用，使用了Abcam公司的抗histone H1.4K26me2抗体来进行蛋白印迹分析。
HIST1H1D
histone cluster 1, H1d
HIST1H1E
histone cluster 1, H1e
总数:1
Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes. 2008 至该文献
为了研究组蛋白去乙酰酶激酶，G蛋白偶联受体激酶-5在心肌细胞核里的作用机制，采用了Cell Signaling公司的组蛋白抗体，进行蛋白质印记实验。
组蛋白H1 (Histone H1)
histone cluster 1, H1c
总数:7
ATM, the Mre11/Rad50/Nbs1 complex, and topoisomerase I are concentrated in the nucleus of Purkinje neurons in the juvenile human brain. 2007 至该文献
为研究人类普肯叶神经元细胞核中基因病AT的机制，采用了Santa Cruz公司的鼠源抗Histone H1单克隆抗体(1:100)进行免疫荧光试验。 更多
高迁移率族蛋白B1 (HMGB1)
high mobility group box 1
总数:9
Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. 2009 至该文献
为了研究在肾脏移植过程中供体Toll样受体4通过诱导局部出血和再灌注对肾脏损伤的影响，使用了Abnova公司的抗HMGB1抗体来进行免疫荧光试验。 更多
高迁移率组b2 (HMGB2)
high mobility group box 2
总数:2
HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIalpha. 2009 至该文献
为了证实HMGB1和HMGB2可以提高人拓扑异构酶IIα的表达水平，使用了Aviva公司的抗HMGB2抗体来检测SDS-PAGE中的HMGB2。 更多
JNK
mitogen-activated protein kinase 8
总数:190
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. 2010 至该文献
为研究如何通过两阶段MAPK反应区分上皮细胞盾壳菌的酵母和菌丝形态，采用了Cell Signaling Technologies公司的抗磷酸化JNK抗体进行蛋白质印迹试验。 更多
KPNA1
karyopherin alpha 1 (importin alpha 5)
总数:1
Novel nuclear import of Vpr promoted by importin alpha is crucial for human immunodeficiency virus type 1 replication in macrophages. 2007 至该文献
KPNB1
karyopherin (importin) beta 1
总数:7
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies. 2010 至该文献
为了说明WRAP53是形成卡恰尔身体的必要因素并且能够将SMN复合体定位到卡恰尔身体，使用了Santa Cruz Biotechnology公司的alpha-importin beta鼠抗(sc-137016)来进行免疫印记，免疫沉淀和免疫细胞组化实验。 更多
lamin A/C
总数:54
The honey bee epigenomes: differential methylation of brain DNA in queens and workers. 2010 至该文献
为了说明WRAP53是形成卡恰尔身体的必要因素并且能够将SMN复合体定位到卡恰尔身体，使用了Santa Cruz Biotechnology公司的alpha-Lamin A/C兔抗(sc-20681)来进行免疫印记，免疫沉淀和免疫细胞组化实验。 更多
核纤层蛋白B (lamin B)
lamin B1
总数:31
CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin. 2010 至该文献
为了表明CYLD负向调控细胞周期是通过使HDAC6失活而实现，采用了Santa Cruz公司的抗lamin-B抗体产品，进行了免疫印迹实验。 更多
MAGED1
melanoma antigen family D, 1
MST4
serine/threonine protein kinase MST4
NMT1
N-myristoyltransferase 1
总数:1
Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. 2005 至该文献
Noxa
phorbol-12-myristate-13-acetate-induced protein 1
总数:4
A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis. 2007 至该文献
OCLN
occludin
总数:20
PKC eta regulates occludin phosphorylation and epithelial tight junction integrity. 2009 至该文献
为了研究PKC在occludin的磷酸化和上皮紧密连接完整性中的作用，采用cell Signaling Technology公司的兔多克隆occludin抗体产品，进行了免疫印迹实验。 更多
p44S10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PA200
proteasome (prosome, macropain) activator subunit 4
总数:1
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体调节蛋白PA200抗体,进行了蛋白质印迹实验.
Pak2
p21 protein (Cdc42/Rac)-activated kinase 2
总数:6
Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death. 2009 至该文献
为了研究PAK-2在调控抗癌药物诱发细胞凋亡中的作用，采用了Santa Cruz Biotechnology 公司的抗PAK-2抗体产品，进行了免疫印迹实验 更多
PKC delta
protein kinase C, delta
总数:36
SphK1 regulates proinflammatory responses associated with endotoxin and polymicrobial sepsis. 2010 至该文献
为了探讨SphK1在调节内毒素信号和败血症引起的炎症反应中的作用，使用了Santa Cruz Biotechnology公司的抗PRKCD抗体来进行免疫印迹分析。 更多
plakophilin 1
plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
总数:1
Defining desmosomal plakophilin-3 interactions. 2003 至该文献
PLEC
plectin
总数:5
Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength. 2009 至该文献
为了研究β3 integrin介导的vimentin中间纤维细胞表面募集的功能，使用了Epitomics公司的兔抗plectin单克隆抗体来进行免疫印迹分析和免疫荧光实验。 更多
PPP3CC
protein phosphatase 3, catalytic subunit, gamma isozyme
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
总数:3
Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. 2006 至该文献
为了研究ASK1和控制心肌病死亡和生长的钙调磷蛋白磷酸酶-NFAT之间的直接相互作用和可逆调节，采用了Sigma公司的CnB1抗体进行了蛋白质印迹分析 更多
PRKCQ
protein kinase C, theta
总数:10
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 至该文献
为了证明CCL2通过Rho/PKCalpha信号通道相互作用引起脑内皮的通透性过高，使用了Cell Signaling Technology公司的抗磷酸-PKC-theta抗体，进行了免疫印迹实验。 更多
PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
总数:9
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 至该文献
PSMA2
proteasome (prosome, macropain) subunit, alpha type, 2
总数:4
The ubiquitin-associated domain of hPLIC-2 interacts with the proteasome. 2003 至该文献
PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3
总数:3
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 至该文献
为了研究内着丝粒是如何建立的和CPC复合物是如何靶向到此位点的机制，使用了Santa Cruz Biotechnology公司的抗Psc3抗体来进行染色质免疫沉淀实验。 更多
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
总数:2
Polo-like kinase interacts with proteasomes and regulates their activity. 2001 至该文献
PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
总数:2
Sem1p is a novel subunit of the 26 S proteasome from Saccharomyces cerevisiae. 2004 至该文献
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
总数:2
Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation. 2009 至该文献
为了在内质网相关蛋白的降解途径（ERAD）中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能，使用了Enzo Life Sciences公司的抗体alpha6来进行免疫印迹分析。 更多
PSMA7
proteasome (prosome, macropain) subunit, alpha type, 7
总数:4
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 至该文献
为了在内质网相关蛋白的降解途径（ERAD）中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能，使用了Enzo Life Sciences公司的抗体alpha7来进行免疫印迹分析。 更多
PSMA8
proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1
proteasome (prosome, macropain) subunit, beta type, 1
总数:2
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体亚基β1抗体,进行了蛋白质印迹实验. 更多
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
PSMB11
proteasome (prosome, macropain) subunit, beta type, 11
PSMB2
proteasome (prosome, macropain) subunit, beta type, 2
总数:1
Characterization of mammalian Ecm29, a 26 S proteasome-associated protein that localizes to the nucleus and membrane vesicles. 2004 至该文献
PSMB3
proteasome (prosome, macropain) subunit, beta type, 3
总数:1
Characterization of mammalian Ecm29, a 26 S proteasome-associated protein that localizes to the nucleus and membrane vesicles. 2004 至该文献
PSMB4
proteasome (prosome, macropain) subunit, beta type, 4
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
总数:1
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体亚基β5抗体,进行了蛋白质印迹实验.
PSMB6
proteasome (prosome, macropain) subunit, beta type, 6
PSMB7
proteasome (prosome, macropain) subunit, beta type, 7
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
总数:2
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体亚基β5i抗体,进行了蛋白质印迹实验. 更多
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
总数:1
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体亚基β1i抗体,进行了蛋白质印迹实验.
PSMC1
proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2
proteasome (prosome, macropain) 26S subunit, ATPase, 2
总数:3
Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation. 2009 至该文献
为了在内质网相关蛋白的降解途径（ERAD）中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能，使用了Enzo Life Sciences公司的抗体Rpt1来进行免疫印迹分析。 更多
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
总数:2
Sem1p is a novel subunit of the 26 S proteasome from Saccharomyces cerevisiae. 2004 至该文献
PSMC4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
总数:8
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 至该文献
为了研究在帕金森疾病模型中雷怕霉素对神经元的保护作用，采用了Cell Signaling Technology的抗phospho-Ser235/236-S6抗体进行免疫细胞化学试验。 更多
PSMC5
proteasome (prosome, macropain) 26S subunit, ATPase, 5
总数:3
Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response. 2004 至该文献
为了研究p65/RelA通过蛋白酶降解，而且它的降解不仅仅调节量和稳定性同时也促使转录水平的终止，采用了Affinity BioReagents公司Sug1抗体，进行蛋白质印记实验。 更多
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
总数:1
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 至该文献
PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
总数:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 至该文献
为了说明hHR23A介导的Vpr与蛋白酶体的互作在病毒复制过程中有重要作用，使用了Calbiochem公司的19S蛋白酶体S2亚基的兔多抗来进行免疫印记实验。
PSMD4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
总数:3
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 至该文献
为了说明hHR23A介导的Vpr与蛋白酶体的互作在病毒复制过程中有重要作用，使用了Calbiochem公司的19S蛋白酶体S5a亚基的兔多抗来进行免疫印记实验。 更多
PSMD5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
总数:12
Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours. 2008 至该文献
为了在胃肠道间质细胞瘤中细胞周期调节因子的作用，采用了BD Transduction Laboratories的抗p27抗体进行免疫组化实验。 更多
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
总数:2
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 至该文献
为了确认长期酒精喂养对蛋白酶体相互作用蛋白表达的影响，采用了BIOMOL公司的抗PA28α抗体进行免疫印迹法实验。 更多
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
总数:1
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 至该文献
为了确认长期酒精喂养对蛋白酶体相互作用蛋白表达的影响，采用了BIOMOL公司的抗PA28β抗体进行免疫印迹法实验。
PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
美洲狮 (PUMA)
BCL2 binding component 3
总数:10
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. 2011 至该文献
为了研究化疗对线粒体激发高的病人有着良好的治疗效果，采用Cell Signaling的抗PUMA抗体进行蛋白印迹实验。 更多
RIP
receptor (TNFRSF)-interacting serine-threonine kinase 1
总数:9
Repression of NF-kappaB and activation of AP-1 enhance apoptosis in prostate cancer cells. 2009 至该文献
为研究NF-κB的抑制和AP-1的激活对前列腺癌细胞凋亡的影响，将Santa Cruz提供的抗RIP抗体用于蛋白免疫印迹实验中。 更多
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
总数:8
Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. 2009 至该文献
为了研究ROCK1和ROCK2在调节角化细胞黏附和终末分化中的不同作用，采用了Santa Cruz的抗ROCK1抗体进行免疫印迹实验 更多
S3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
SATB1
SATB homeobox 1
总数:2
Acetylation-dependent interaction of SATB1 and CtBP1 mediates transcriptional repression by SATB1. 2009 至该文献
使用Santa Cruz生物公司的乙酰化SATB1抗体进行免疫印记实验研究T细胞 Wnt信号通路中SATB1-CtBP1相互作用在阻遏和去阻遏SATB1目的基因中的作用 更多
Smac
diablo, IAP-binding mitochondrial protein
总数:16
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. 2008 至该文献
为了研究保护性自体吞噬与凋亡缺陷肿瘤细胞TRAIL耐受的关连，采用了Cell Signaling的抗SMAC抗体进行免疫细胞化学试验。 更多
SPTAN1
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
总数:2
Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29. 2002 至该文献
STK24
serine/threonine kinase 24
总数:1
Targeted disruption of the gene for the PAK5 kinase in mice. 2003 至该文献
为了研究PAK5激酶在小鼠中的靶向分裂，采用了Upstate Biotechnology公司的Ste20抗体进行蛋白质印迹分析。
tau
microtubule-associated protein tau
总数:45
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 至该文献
为了说明YB-1、GST、ABCB5和ERK3能够成为乳腺癌细胞耐药性治疗的潜在靶点，使用了Proteintech Group公司的MAPT抗体(1:1500)来进行免疫印记实验。 更多
TJP2
tight junction protein 2 (zona occludens 2)
总数:3
EspF Interacts with nucleation-promoting factors to recruit junctional proteins into pedestals for pedestal maturation and disruption of paracellular permeability. 2008 至该文献
TNF-alpha
tumor necrosis factor
总数:64
Local and systemic responses in matrix metalloproteinase 8-deficient mice during Porphyromonas gingivalis-induced periodontitis. 2009 至该文献
为了研究牙龈卟啉单胞菌所致牙周炎中基质金属蛋白酶8的作用，在免疫染色试验中将R&D Systems的tumor necrosis factor alpha作用于石蜡包被的组织样品上。 更多
TNFR1
tumor necrosis factor receptor superfamily, member 1A
总数:23
Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation. 2009 至该文献
为了研究TRAF2对应激诱导的细胞死亡的抑制机制，采用了Santa Cruz的抗TNFR1抗体进行免疫印迹实验 更多
TRADD
TNFRSF1A-associated via death domain
总数:6
AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation. 2004 至该文献
TRAF2
TNF receptor-associated factor 2
总数:25
Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination. 2011 至该文献
为了利用cIAP1的自身泛素化能够被拮抗剂诱导的cIAP1的构象改变所促进，采用Santa Cruz的抗TRAF2抗体进行蛋白印迹实验。 更多
TRAIL
tumor necrosis factor (ligand) superfamily, member 10
总数:6
Small interference RNA-mediated gene silencing of human biliverdin reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells. 2005 至该文献
泛素蛋白A52残基核糖体蛋白融合产物1 (UBA52)
ubiquitin A-52 residue ribosomal protein fusion product 1
总数:22
Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region. 2004 至该文献
为了研究在干细胞因子复合体中Fbx7和Cdk1-细胞周期蛋白B-磷酸肝癌上调蛋白的相互作用，在免疫印迹试验中使用了Santa Cruz Biotechnology的抗泛素抗体。 更多
UBB
ubiquitin B
总数:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 至该文献
为了阐明BCL6和HB-EGF-CTF相互作用，并且这种相互作用可能会引起细胞周期蛋白D2在人胃癌细胞中表达，采用了Cell Signaling Technology公司的小鼠抗泛素单克隆抗体，进行了蛋白质印迹实验。 更多
UBC
ubiquitin C
总数:4
Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family. 2007 至该文献
为了研究人切片中PGRN的遗传变异性是否与其他的神经变性疾病有关，比如阿尔茨海默病（AD）或者帕金森病(PD)，采用了Dako公司的抗泛素的抗体进行免疫组织化学分析。 更多
泛肽 (ubiquitin)
ribosomal protein S27a
总数:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 至该文献
为了在内质网相关蛋白的降解途径（ERAD）中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能，使用了Santa Cruz Biotechnology公司的抗体ubiquitin来进行免疫印迹分析。 更多
UNC5A
unc-5 homolog A (C. elegans)
UNC5H2
unc-5 homolog B (C. elegans)
总数:1
Unc5B associates with LARG to mediate the action of repulsive guidance molecule. 2009 至该文献
为了研究Unc5B and LARG在调控斥性轴突导向分子中的作用，采用了R&D Systems公司的Unc5B抗体产品,来进行免疫印迹实验。
弹性蛋白 (vimentin)
总数:75
Vimentin filaments support extension of tubulin-based microtentacles in detached breast tumor cells. 2008 至该文献
为了研究游离的乳腺瘤细胞形成基于微管蛋白的微触角的机制，采用了Santa Cruz Biotechnology公司的抗vimentin（C-20和H-84，1：1000）抗体进行免疫印迹实验。 更多
XIAP
X-linked inhibitor of apoptosis
总数:28
The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis. 2008 至该文献
为了研究天然产物honokiol的作用使用了 Cell Signaling Technology 公司的兔抗XIAP多克隆抗体来进行蛋白印迹实验。 更多
YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
总数:9
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 至该文献
14-3-3β抗体以1/1000稀释，进行蛋白质印迹实验。 更多
ZIP
death-associated protein kinase 3
ZO 1
tight junction protein 1 (zona occludens 1)
总数:53
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 至该文献
为了研究MMP-10和CTSF在糖尿病患者角膜伤口治愈不良中的作用，采用了Invitrogen的抗ZO-1抗体进行免疫组化试验。 更多