生物氧化
基因
试剂
文献样例
产品评述样例
21羟化酶 (21 hydroxylase)
cytochrome P450, family 21, subfamily A, polypeptide 2
总数:1
Expression of Cyp21a1 and Cyp11b1 in the fetal mouse testis. 2007 至该文献
ACSS1
acyl-CoA synthetase short-chain family member 1
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
总数:2
A pilot study on subacute ethanol treatment of ALDH2 KO mice. 2007 至该文献
ALDH2
aldehyde dehydrogenase 2 family (mitochondrial)
总数:1
A pilot study on subacute ethanol treatment of ALDH2 KO mice. 2007 至该文献
芳香酶 (aromatase)
cytochrome P450, family 19, subfamily A, polypeptide 1
总数:7
IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells. 2009 至该文献
为了研究在脂肪基质细胞(ASCs)中对芳香化酶转录和雌性激素生物合成的调控机制,采用了Serotec公司的α-芳香化酶抗体,进行了蛋白质印迹实验。 更多
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
总数:13
Cyclooxygenase-2 is involved in the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma induced by tumor necrosis factor-alpha. 2009 至该文献
为了证实环氧酶2可以调节胆管癌患者基质金属蛋白酶9的表达上调,使用了Santa Cruz公司的抗COX-1抗体来进行蛋白印迹分析和免疫组化分析。 更多
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
总数:58
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2010 至该文献
为了研究mPGES-1在调控肿瘤生长、侵润和转移中的作用,采用了Santa Cruz Biotechnology公司的抗COX-2抗体产品,进行了免疫印迹实验。 更多
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
总数:3
Complex role of the mitochondrial targeting signal in the function of steroidogenic acute regulatory protein revealed by bacterial artificial chromosome transgenesis in vivo. 2008 至该文献
CYP11B1
cytochrome P450, family 11, subfamily B, polypeptide 1
总数:1
Expression of Cyp21a1 and Cyp11b1 in the fetal mouse testis. 2007 至该文献
CYP11B2
cytochrome P450, family 11, subfamily B, polypeptide 2
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
总数:1
Colocalization of P450c17 and cytochrome b5 in androgen-synthesizing tissues of the human. 2004 至该文献
Cyp1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
总数:19
Toxicogenomic analysis of mainstream tobacco smoke-exposed mice reveals repression of plasminogen activator inhibitor-1 gene in heart. 2009 至该文献
为了通过分析吸烟老鼠的毒物基因组变化以揭示心脏中纤溶酶原激活物抑制剂基因表达的抑制,采用了Santa cruz公司的抗Cyp1A1抗体,用来进行免疫印迹分析。 更多
CYP1A2
cytochrome P450, family 1, subfamily A, polypeptide 2
总数:4
The role of the dioxin-responsive element cluster between the Cyp1a1 and Cyp1a2 loci in aryl hydrocarbon receptor biology. 2009 至该文献
为证实DREC能调控Cyp1a1和Cyp1a2基因的表达,使用了Human Biologics公司的抗Cyp1a2抗体来进行蛋白印迹分析。 更多
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
总数:9
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 至该文献
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
CYP26C1
cytochrome P450, family 26, subfamily C, polypeptide 1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
总数:1
CYP2A13 in human respiratory tissues and lung cancers: an immunohistochemical study with a new peptide-specific antibody. 2006 至该文献
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
总数:6
Effects of avasimibe on cytochrome P450 2C9 expression in vitro and in vivo. 2004 至该文献
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
总数:3
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. 2009 至该文献
为了介绍在急性肾损伤时线粒体动力学的一种快速调节,使用了BD Biosciences — Pharmingen公司的单克隆抗cytochrome c抗体来进行免疫组化实验。 更多
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
总数:4
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 至该文献
CYP2D6
cytochrome P450, family 2, subfamily D, polypeptide 6
总数:1
CYP2D6, GST-M1 and GST-T1 enzymes: expression in parathyroid gland and association with the parathyroid hormone concentration during early renal replacement therapy. 2003 至该文献
Cyp2e1
cytochrome P450, family 2, subfamily E, polypeptide 1
总数:10
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 至该文献
使用牛津大学生物医学研究的抗CYP2E1(1:1000) 抗体进行免疫印迹实验来研究心肌CPR和CPR依赖酶在阿霉素介导的急性心脏毒性中的作用。 更多
CYP2F1
cytochrome P450, family 2, subfamily F, polypeptide 1
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
总数:1
Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8, 2C9, and 2J2 in human tissues. 2004 至该文献
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
CYP2U1
cytochrome P450, family 2, subfamily U, polypeptide 1
总数:1
CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids. 2004 至该文献
CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
总数:12
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 至该文献
使用BIOMOL国际的抗CYP3A2(1:1000) 抗体进行免疫印迹实验来研究心肌CPR和CPR依赖酶在阿霉素介导的急性心脏毒性中的作用。 更多
CYP3A43
cytochrome P450, family 3, subfamily A, polypeptide 43
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 5
总数:1
Differential mechanism-based inhibition of CYP3A4 and CYP3A5 by verapamil. 2005 至该文献
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
总数:3
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 至该文献
CYP4F11
cytochrome P450, family 4, subfamily F, polypeptide 11
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
CYP4F8
cytochrome P450, family 4, subfamily F, polypeptide 8
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
CYP7B1
cytochrome P450, family 7, subfamily B, polypeptide 1
CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
FMO1
flavin containing monooxygenase 1
总数:2
Human kidney flavin-containing monooxygenases and their potential roles in cysteine s-conjugate metabolism and nephrotoxicity. 2003 至该文献
FMO2
flavin containing monooxygenase 2 (non-functional)
GCLC
glutamate-cysteine ligase, catalytic subunit
GCLM
glutamate-cysteine ligase, modifier subunit
谷胱甘肽S-转移酶 (GST)
glutathione S-transferase alpha 1
总数:17
The nucleocapsid protein of severe acute respiratory syndrome coronavirus inhibits cell cytokinesis and proliferation by interacting with translation elongation factor 1alpha. 2008 至该文献
Santa Cruz公司生产的抗GST抗体可用于免疫印迹,来研究严重急性呼吸窘迫综合症核体蛋白与转录延伸因子1在细胞分裂与增殖过程中的交互作用。 更多
GSTA2
glutathione S-transferase alpha 2
总数:2
Oligomerization of human Gadd45a protein. 2001 至该文献
GSTO1
glutathione S-transferase omega 1
总数:1
Decreased liver fatty acid binding capacity and altered liver lipid distribution in mice lacking the liver fatty acid-binding protein gene. 2003 至该文献
GSTP1
glutathione S-transferase pi 1
总数:10
Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4. 2009 至该文献
为了说明Toll样受体4在革兰氏阴性菌脂多糖信号转导,采用了Sigma的鼠 GG-7 Fc-特异抗人免疫球蛋白抗体用来确认人免疫球蛋白中Fc片段的存在。 更多
MACS1
acyl-CoA synthetase medium-chain family member 1
MAOA
monoamine oxidase A
总数:1
The existence of a local 5-hydroxytryptaminergic system in peripheral arteries. 2008 至该文献
为了检测具有生理机能的5羟色胺能系统是否存在于外周动脉,采用了Santa Cruz Biotechnology的兔MAO A基因的多抗(H-70,可以识别人类MAO A的458-527号氨基酸),进行免疫组化和蛋白质印迹实验
MAT1A
methionine adenosyltransferase I, alpha
总数:1
Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite. 2003 至该文献
MAT2A
methionine adenosyltransferase II, alpha
MAT2B
methionine adenosyltransferase II, beta
MGST1
microsomal glutathione S-transferase 1
MGST2
microsomal glutathione S-transferase 2
MGST3
microsomal glutathione S-transferase 3
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase
NAT1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
总数:1
Quantification of phase I/II metabolizing enzyme gene expression and polycyclic aromatic hydrocarbon-DNA adduct levels in human prostate. 2009 至该文献
NAT2
N-acetyltransferase 2 (arylamine N-acetyltransferase)
烟酰胺N甲基转移酶 (nicotinamide N methyltransferase)
nicotinamide N-methyltransferase
总数:1
Nicotinamide N-methyltransferase upregulation inversely correlates with lymph node metastasis in oral squamous cell carcinoma. 2007 至该文献
PAOX
polyamine oxidase (exo-N4-amino)
PGIS
prostaglandin I2 (prostacyclin) synthase
总数:4
Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages. 2005 至该文献
SLC35D1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
sterol 27 hydroxylase
cytochrome P450, family 27, subfamily A, polypeptide 1
总数:2
Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble in noncaveolar plasma membrane microdomains defined by reggie-1 and -2. 2001 至该文献
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
总数:1
All-trans retinoic acid induction of sulfotransferases. 2005 至该文献
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
SULT1C2
sulfotransferase family, cytosolic, 1C, member 2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
总数:1
Neuronal intranuclear inclusions in SCA2: a genetic, morphological and immunohistochemical study of two cases. 2002 至该文献
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
总数:5
Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre- and postnatal human liver. 2006 至该文献
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
总数:3
Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre- and postnatal human liver. 2006 至该文献
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
总数:2
Oxysterols are substrates for cholesterol sulfotransferase. 2007 至该文献
TBXAS1
thromboxane A synthase 1 (platelet)
总数:2
Nucleobindin co-localizes and associates with cyclooxygenase (COX)-2 in human neutrophils. 2008 至该文献
TPMT
thiopurine S-methyltransferase
UGP2
UDP-glucose pyrophosphorylase 2
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
总数:3
Novel identification of UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene. 2008 至该文献
Gentest的抗UGT1A抗体(1:500)被用于蛋白质印迹实验,来证明UDP-葡萄糖醛酸转移酶1A10基因是一种雌激素调节的靶基因。 更多
UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A3
UGT1A4
UDP glucuronosyltransferase 1 family, polypeptide A4
总数:2
Critical roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4. 2007 至该文献
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A5
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
总数:1
Human CYP1A1GFP expression in transgenic mice serves as a biomarker for environmental toxicant exposure. 2007 至该文献
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B10
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
UGT2B28
UDP glucuronosyltransferase 2 family, polypeptide B28
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7