CTLA4 inhibitory signaling
基因
试剂
文献样例
产品评述样例
Akt
AKT serine/threonine kinase 1
总数:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 至该文献
为了研究磷酸肌醇激酶3在调节细胞因子依赖性细胞存活中的作用，采用了Cell Signalling公司的抗磷酸化Ser473Akt抗体进行了免疫印迹试验。 更多
AKT3
AKT serine/threonine kinase 3
总数:4
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. 2008 至该文献
为了研究抑制Akt通路后PTEN缺失的肿瘤自噬增多，并对趋溶酶体剂更敏感，采用了Millipore的抗Akt3抗体进行免疫印迹实验。 更多
CD80
CD80 molecule
总数:24
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 至该文献
为了研究肠道正常菌群如何调节免疫系统，采用了Beckman 抗CD80抗体进行了流式分析检测。 更多
CD86
CD86 molecule
总数:23
CD4CD8?? lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. 2014 至该文献
为了研究肠道正常菌群如何调节免疫系统，采用了Beckman 抗CD86抗体进行了流式分析检测。 更多
CTLA 4 (CTLA 4)
cytotoxic T-lymphocyte associated protein 4
总数:6
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. 2011 至该文献
为了揭示CTLA-4为何能够抑制CD28的激活，采用Santa Cruz的抗CTLA-4抗体进行免疫细胞化学试验。 更多
Fyn
FYN proto-oncogene, Src family tyrosine kinase
总数:19
An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking. 2009 至该文献
为了研究DC ehrlichiae对细胞信号，转录调控及小泡转运方面的影响，使用了Santa Cruz Biotechnology公司的兔抗FYN抗体来进行免疫沉淀实验。 更多
Lck
LCK proto-oncogene, Src family tyrosine kinase
总数:18
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 至该文献
Lyn
LYN proto-oncogene, Src family tyrosine kinase
总数:20
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors. 2009 至该文献
为了研究脂质筏依赖的Fc secre tRI泛素化作用对受体的内吞调控过程中所起的作用，使用了Santa Cruz公司的抗Lyn 44抗体来进行蛋白印迹分析。 更多
PP2AC
protein phosphatase 2 catalytic subunit alpha
总数:20
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 至该文献
PPP2CB
protein phosphatase 2 catalytic subunit beta
PPP2R1A
protein phosphatase 2 scaffold subunit Aalpha
总数:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 至该文献
PPP2R1B
protein phosphatase 2 scaffold subunit Abeta
总数:2
SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process. 2007 至该文献
为了研究sk1的功能，采用了Sigma-Aldrich公司的单克隆抗PP2A抗体，进行了蛋白印记实验。 更多
PPP2R5B
protein phosphatase 2 regulatory subunit B'beta
PPP2R5C
protein phosphatase 2 regulatory subunit B'gamma
PPP2R5D
protein phosphatase 2 regulatory subunit B'delta
PPP2R5E
protein phosphatase 2 regulatory subunit B'epsilon
SHP-2 (SHP-2)
protein tyrosine phosphatase non-receptor type 11
总数:34
Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. 2010 至该文献
为了研究在巨噬细胞中TLR和RBP-J对Notch信号自发放大的调节作用，采用Santa Cruz Biotechnology公司多克隆抗Shp2抗体进行了免疫印迹实验。 更多
Src
SRC proto-oncogene, non-receptor tyrosine kinase
总数:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 至该文献
为了研究在管腔乳腺癌中雌激素敏感性以及抗雌激素抗性的获得，采用了Calbiochem的抗SRC抗体进行了western blot实验。 更多
YES1
YES proto-oncogene 1, Src family tyrosine kinase
总数:6
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. 2009 至该文献
为了揭示在CXCL12诱发的T淋巴细胞迁移过程中CRMP2功能的分子机制，采用了Upstate公司的兔抗Yes1(06.514)多克隆抗体进行免疫印迹和免疫细胞化学实验。 更多