G alpha (12/13) signalling events
基因
试剂
文献样例
产品评述样例
ADRA1D
adrenoceptor alpha 1D
总数:1
Circadian-related heteromerization of adrenergic and dopamine D? receptors modulates melatonin synthesis and release in the pineal gland. 2012 至该文献
为了研究肾上腺素和多巴胺D4受体的异二聚体对褪黑激素在松果体里的合成和释放的调节作用,采用了Abcam的兔抗alpha1受体抗体进行了免疫共沉淀和免疫组化试验。
ARHGAP4
Rho GTPase activating protein 4
总数:3
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 至该文献
ARHGEF18
Rho/Rac guanine nucleotide exchange factor 18
ARHGEF7
Rho guanine nucleotide exchange factor 7
总数:1
GM130-dependent control of Cdc42 activity at the Golgi regulates centrosome organization. 2009 至该文献
使用Santa Cruz生物公司的抗-β-PIX 抗体进行免疫印迹实验来研究高尔基体的GM130依赖的Cdc42活性在调节中心体重组过程中的作用。
ARHGEF9
Cdc42 guanine nucleotide exchange factor 9
cdc42
cell division cycle 42
总数:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 至该文献
为了研究肺部发炎部位slit2对嗜酸性粒细胞和嗜中性粒细胞的影响,采用了Santa Cruz Biotechnology公司的抗Cdc42抗体进行蛋白免疫印迹试验。 更多
ECT2
epithelial cell transforming 2
总数:2
CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase. 2009 至该文献
使用Santa Cruz生物公司的抗Ect2抗体进行免疫印迹来研究细胞周期过程中调钙素调节Ect2, MgcRacGAP, 和 MKLP1 表达的作用 更多
FGD1
FYVE, RhoGEF and PH domain containing 1
FGD2
FYVE, RhoGEF and PH domain containing 2
FGD4
FYVE, RhoGEF and PH domain containing 4
Galpha13
G protein subunit alpha 13
总数:7
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 至该文献
为了研究切割的NIK 导致非经典的NF- kB 活性,采用了Abcam的抗BAFF抗体进行免疫印迹试验。 更多
GNA12
G protein subunit alpha 12
总数:6
G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function. 2005 至该文献
GNB5
G protein subunit beta 5
总数:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 至该文献
GRF2
Ras protein specific guanine nucleotide releasing factor 2
MCF2
MCF.2 cell line derived transforming sequence
总数:1
Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1. 2008 至该文献
为了证明Nm23-H1可以通过调节Dbl1的活性负调控细胞迁移和肿瘤转移,采用了Santa Cruz兔抗Dbl-1抗体进行了免疫沉淀和免疫印记实验。
MCF2L
MCF.2 cell line derived transforming sequence like
NET1
neuroepithelial cell transforming 1
总数:1
The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion. 2009 至该文献
为了研究芳香烃受体对组成性的Vav3表达以及细胞可塑性和迁移的调节,使用了Santa Cruz Biotechnology公司的抗Net1抗体来进行免疫印迹分析。
NGEF
neuronal guanine nucleotide exchange factor
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
p110
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
总数:26
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 至该文献
为了研究磷酸肌醇激酶3 在调节细胞因子依赖性细胞存活中的作用,采用了Cell Signalling公司的p110alpha抗体进行了免疫沉淀试验。 更多
p85
phosphoinositide-3-kinase regulatory subunit 1
总数:43
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 至该文献
为了研究磷酸肌醇激酶3 在调节细胞因子依赖性细胞存活中的作用,采用了Upstate公司的p85多克隆抗体进行了免疫沉淀试验。 更多
PIK3R2
phosphoinositide-3-kinase regulatory subunit 2
总数:11
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 至该文献
为了研究PIP5K1α在胞外钙诱导的第二信使IP3的生成和角质形成细胞分化中的功能,使用了Millipore公司的抗人p85多克隆抗体来进行免疫印迹分析。 更多
PLEKHG2
pleckstrin homology and RhoGEF domain containing G2
PLEKHG5
pleckstrin homology and RhoGEF domain containing G5
Ras相关C3肉毒杆菌毒素底物1 (Rac1)
Rac family small GTPase 1
总数:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 至该文献
为研究RhoGDI2通过Rho GTPases抑制代谢的作用,采用了Millipore公司的抗Rac1单克隆抗体(1:1,000)进行免疫印迹试验。 更多
RAC2
Rac family small GTPase 2
总数:3
In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression. 2009 至该文献
为了研究ROR2在淋巴瘤侵润性的作用,采用Proteintech公司的Rac2抗体,进行了蛋白印记实验。 更多
RhoA
ras homolog family member A
总数:49
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 至该文献
为了研究沉默RhoA和RhoC的表达对人类结直肠癌体内生长的影响,采用Santa Cruz公司的抗RhoA抗体进行了免疫组织化学实验。 更多
RhoB
ras homolog family member B
总数:10
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 至该文献
为了研究类鼻疽杆菌的CHBP蛋白作为真核细胞的泛素化途径的强抑制剂的功能,使用了Santa Cruz Biotechnology公司的抗RhoB抗体来进行免疫印迹分析。 更多
RhoC
ras homolog family member C
总数:5
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 至该文献
为了研究沉默RhoA和RhoC的表达对人类结直肠癌体内生长的影响,采用Santa Cruz公司的抗RhoC抗体进行了免疫组织化学实验。 更多
ROCK1
Rho associated coiled-coil containing protein kinase 1
总数:8
Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. 2009 至该文献
为了研究ROCK1和ROCK2在调节角化细胞黏附和终末分化中的不同作用,采用了Santa Cruz的抗ROCK1抗体进行免疫印迹实验 更多
ROCK2
Rho associated coiled-coil containing protein kinase 2
总数:5
RhoE Is required for keratinocyte differentiation and stratification. 2009 至该文献
为研究RhoE在角质化细胞的分化和层化过程中所发挥的角色,将Santa Cruz提供的兔多克隆抗ROCKII抗体(H-85)用于蛋白免疫印迹实验中。 更多
Sos
SOS Ras/Rac guanine nucleotide exchange factor 1
总数:11
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 至该文献
Santa Cruz的兔Sos-1抗体被用于蛋白质印迹实验,来研究Abi-1在形态发生和突触形成中的作用。 更多
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2
总数:1
The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis. 2005 至该文献
Tiam1
TIAM Rac1 associated GEF 1
总数:6
Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells. 2008 至该文献
为了阐明结肠癌细胞中Rac1与经典Wnt信号通路之间的关系,使用了Santa Cruz Biotechnology公司的Tiam1抗体(C-16)来进行免疫沉淀和染色质沉淀实验。 更多
VAV3
vav guanine nucleotide exchange factor 3
总数:2
Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer. 2008 至该文献
XPLN
Rho guanine nucleotide exchange factor 3