G alpha (q) signalling events
基因
试剂
文献样例
产品评述样例
ADRA1D
adrenoceptor alpha 1D
总数:1
Circadian-related heteromerization of adrenergic and dopamine D? receptors modulates melatonin synthesis and release in the pineal gland. 2012 至该文献
为了研究肾上腺素和多巴胺D4受体的异二聚体对褪黑激素在松果体里的合成和释放的调节作用,采用了Abcam的兔抗alpha1受体抗体进行了免疫共沉淀和免疫组化试验。
AGT
angiotensinogen
总数:6
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. 2008 至该文献
AGTR1
angiotensin II receptor type 1
总数:9
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 至该文献
为了研究缺血性心脏病病人体内ETB和AT1受体表达量上调,采用Santa Cruz的兔抗AT1抗体进行免疫组织化学实验。 更多
膜联蛋白I (Annexin I)
annexin A1
总数:7
Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia. 2010 至该文献
为了研究膜联蛋白A1在小胶质细胞的消炎和神经保护作用中的功能,采用了Invitrogen的抗ANXA1抗体进行免疫组化,免疫印迹和酶联免疫吸附实验。 更多
淀粉样蛋白前体 (APP)
amyloid beta precursor protein
总数:81
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 至该文献
为了研究通过定量蛋白质组学发现新的BACE1底物,采用Chemicon的APP抗体以1:1,000稀释进行蛋白印迹实验。 更多
ARHGEF25
Rho guanine nucleotide exchange factor 25
总数:1
Modulation of muscle regeneration, myogenesis, and adipogenesis by the Rho family guanine nucleotide exchange factor GEFT. 2005 至该文献
为了阐述Rho-GEFs在调节骨骼肌肉再生,肌细胞生成和成脂中的功能,使用了Proteintech Group公司兔抗GEFT抗体来进行免疫组化实验和免疫印迹分析。
AVP
arginine vasopressin
总数:1
Involvement of alcohol and aldehyde dehydrogenase activities on hepatic retinoid metabolism and its possible participation in the progression of rat liver regeneration. 2007 至该文献
为研究乙醇和乙醛醛脱氢酶在小鼠肝再生过程中的作用,采用Santa Cruz公司生产的I 型ADH抗体用于免疫印迹实验。
AVPR1A
arginine vasopressin receptor 1A
总数:1
Prolactin activates mitogen-activated protein kinase signaling and corticotropin releasing hormone transcription in rat hypothalamic neurons. 2009 至该文献
为了研究在体内外催乳素是怎样影响促肾上腺素释放激素在下丘脑神经元转录 ,采用了Aachen公司的VP单克隆荧光标记抗体,进行免疫组织化学实验。
钙感应受体 (calcium sensing receptor)
总数:4
ASB4 is a hydroxylation substrate of FIH and promotes vascular differentiation via an oxygen-dependent mechanism. 2007 至该文献
Novus的抗FIH抗体被用于蛋白质印迹实验,来研究ASB4和FIH在人HEK-293T细胞中的相互作用。 更多
CHRM1
cholinergic receptor muscarinic 1
总数:3
M(1) and M(2) muscarinic acetylcholine receptor subtypes mediate Ca(2+) channel current inhibition in rat sympathetic stellate ganglion neurons. 2006 至该文献
DGKQ
diacylglycerol kinase theta
总数:1
Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C. 2005 至该文献
EDNRA
endothelin receptor type A
总数:6
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 至该文献
为了研究缺血性心脏病病人体内ETB和AT1受体表达量上调,采用Santa Cruz的山羊抗ETA抗体以1:50稀释进行免疫组织化学实验。 更多
EDNRB
endothelin receptor type B
总数:10
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 至该文献
为了研究缺血性心脏病病人体内ETB和AT1受体表达量上调,采用IBL的兔抗ETB抗体以1:400稀释进行免疫组织化学实验。 更多
内皮素1 (endothelin 1)
总数:9
Expression of endothelial nitric oxide synthase and endothelin-1 in skin tissue from amputated limbs of patients with complex regional pain syndrome. 2008 至该文献
为了检测eNOS和ET-1的分布与在切断四肢的CRPS病人的皮肤组织中通过由内皮标记CD31免疫反应代表的血管浓度有关,采用R&D systems鼠的抗人ET-1抗体(3G10),进行免疫组织化学实验。 更多
EP1
prostaglandin E receptor 1
总数:4
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2009 至该文献
为了研究mPGES-1在调控肿瘤生长、侵润和转移中的作用,采用了Cayman Chemicals公司的抗EP1抗体产品,进行了免疫印迹实验。 更多
F2RL2
coagulation factor II thrombin receptor like 2
总数:2
Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. 2005 至该文献
Upstate Biotechnologies的Par-3抗体被用于蛋白质印迹和免疫细胞化学实验,来研究Par-3在哺乳动物上皮细胞极化过程中的作用。 更多
FPR2
formyl peptide receptor 2
总数:1
The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells. 2009 至该文献
使用LifeSpan生物公司的抗FPRL1抗体(1:100)进行流式细胞计数来研究促炎症反应多肽LL-37在卵巢肿瘤进展中的作用。
胃泌素 (gastrin)
总数:5
Secretin-receptor and secretin-receptor-variant expression in gastrinomas: correlation with clinical and tumoral features and secretin and calcium provocative test results. 2007 至该文献
胰高血糖素 (glucagon)
总数:13
Deletion of the mitochondrial flavoprotein apoptosis inducing factor (AIF) induces beta-cell apoptosis and impairs beta-cell mass. 2009 至该文献
为了研究线粒体黄素蛋白细胞凋亡诱导因子的效应,使用了西格玛公司的抗胰高血糖素抗体来进行免疫组化分析。 更多
GNAQ
G protein subunit alpha q
总数:11
Caveolin-1 alters Ca(2+) signal duration through specific interaction with the G alpha q family of G proteins. 2008 至该文献
使用Santa Cruz 生物公司的抗Gαq抗体进行免疫组化实验来研究caveolin-1 和G蛋白家族Gαq 在钙信号持续过程中的相互作用效果。 更多
GNB5
G protein subunit beta 5
总数:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 至该文献
GNRH1
gonadotropin releasing hormone 1
总数:5
Presence of immunoreactive gonadotropin releasing hormone (GnRH) and its receptor (GnRHR) in rat ovary during pregnancy. 2008 至该文献
GPR68
G protein-coupled receptor 68
GPRC6A
G protein-coupled receptor class C group 6 member A
GRK2
G protein-coupled receptor kinase 2
总数:9
Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2. 2008 至该文献
为了研究在冠状动脉旁路移植中,GRK2对心肌肾上腺素受体信号解偶联的作用,采用了Santa Cruz Biotechnolog的GRK2多抗,进行心肌衰弱水平的免疫检测 更多
GRK5
G protein-coupled receptor kinase 5
总数:3
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. 2009 至该文献
为了研究在人的近曲小管细胞中GRK4对于D3受体信号传导的重要作用,使用了Santa Cruz Biotechnology公司的抗GRK5多克隆抗体进行免疫印迹实验。 更多
GRM1
glutamate metabotropic receptor 1
总数:7
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 至该文献
GRM5
glutamate metabotropic receptor 5
总数:3
Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin. 2005 至该文献
GRPR
gastrin releasing peptide receptor
总数:1
Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon. 2005 至该文献
HCRTR1
hypocretin receptor 1
总数:4
Repeated amphetamine administration induces Fos in prefrontal cortical neurons that project to the lateral hypothalamus but not the nucleus accumbens or basolateral amygdala. 2008 至该文献
为了确认额叶皮层通路可以被AMPH的敏感部位激活,采用了Santa Cruz生物技术公司的抗食欲A抗体(1:1000)进行了免疫组化实验。 更多
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
总数:5
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 至该文献
为了研究在Purkinje神经元细胞膜钙ATP酶2缺失的小脑的分子变化,采用了Calbiochem公司的IP3R1抗体进行蛋白质印迹杂家和免疫组织化学分析。 更多
ITPR2
inositol 1,4,5-trisphosphate receptor type 2
总数:2
Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression. 2005 至该文献
KiSS 1 (KiSS 1)
KiSS-1 metastasis suppressor
总数:3
Large isoform of MRJ (DNAJB6) reduces malignant activity of breast cancer. 2008 至该文献
KNG1
kininogen 1
总数:1
Estrogen receptor-beta activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFalpha mediated. 2010 至该文献
为了研究雌激素受体beta激活的凋亡的调节机制和它的拮抗物在癌症治疗中的作用,使用了Santa Cruz Biotechnology公司的抗CKH抗体来进行免疫组化试验。
LPAR1
lysophosphatidic acid receptor 1
总数:1
The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases. 2006 至该文献
为了研究溶血磷脂酸一型受体在处理骨转移中所起的作用,使用Abgent公司抗LPA1抗体进行western blot 实验
LTB4R
leukotriene B4 receptor
总数:2
Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. 2005 至该文献
LTB4R2
leukotriene B4 receptor 2
总数:1
Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. 2005 至该文献
MCHR1
melanin concentrating hormone receptor 1
总数:1
Periplakin interferes with G protein activation by the melanin-concentrating hormone receptor-1 by binding to the proximal segment of the receptor C-terminal tail. 2005 至该文献
MCHR2
melanin concentrating hormone receptor 2
神经降压素 (neurotensin)
总数:1
The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression. 2009 至该文献
为了研究神经降压素受体1通路在导管型乳腺癌演变中的作用,采用Biomol公司的NTS兔抗抗体产品,进行了免疫组化实验。
NPFF
neuropeptide FF-amide peptide precursor
NTSR1
neurotensin receptor 1
总数:3
The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression. 2009 至该文献
为了研究神经降压素受体1通路在导管型乳腺癌演变中的作用,采用Santa Cruz公司的NTSR1羊多克隆抗体产品,进行了免疫组化实验。 更多
orexin
hypocretin neuropeptide precursor
总数:8
Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia. 2008 至该文献
Santa Cruz公司生产的抗orexin-B抗体(1:5000)可用于免疫组化实验,来研究Hcrt和痛敏肽/孤啡肽在共同调控下丘脑垂体疾病SIA中的相互作用。 更多
OXT
oxytocin/neurophysin I prepropeptide
总数:4
Prolactin activates mitogen-activated protein kinase signaling and corticotropin releasing hormone transcription in rat hypothalamic neurons. 2009 至该文献
为了研究在体内外催乳素是怎样影响促肾上腺素释放激素在下丘脑神经元转录 ,采用了Chemicon Temecula公司的催产素单克隆荧光标记抗体,进行免疫组织化学实验。 更多
p110
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
总数:26
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 至该文献
为了研究磷酸肌醇激酶3 在调节细胞因子依赖性细胞存活中的作用,采用了Cell Signalling公司的p110alpha抗体进行了免疫沉淀试验。 更多
P2Y1
purinergic receptor P2Y1
总数:2
Possible role of extracellular nucleotides in ectopic ossification of human spinal ligaments. 2008 至该文献
为了研究在人细胞脊柱韧带的异位性骨化中胞外核苷酸的作用,采用了Alomone Labs公司的抗P2Y1抗体进行蛋白质印迹分析。 更多
p85
phosphoinositide-3-kinase regulatory subunit 1
总数:43
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 至该文献
为了研究磷酸肌醇激酶3 在调节细胞因子依赖性细胞存活中的作用,采用了Upstate公司的p85多克隆抗体进行了免疫沉淀试验。 更多
PAR-1 (PAR-1)
coagulation factor II thrombin receptor
总数:7
Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder. 2007 至该文献
PAR-2 (PAR-2)
F2R like trypsin receptor 1
总数:6
Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder. 2007 至该文献
磷脂酶C乙4 (phospholipase C beta 4)
总数:2
A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients. 2005 至该文献
PIK3R2
phosphoinositide-3-kinase regulatory subunit 2
总数:11
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 至该文献
为了研究PIP5K1α在胞外钙诱导的第二信使IP3的生成和角质形成细胞分化中的功能,使用了Millipore公司的抗人p85多克隆抗体来进行免疫印迹分析。 更多
PKC delta
protein kinase C delta
总数:35
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. 2009 至该文献
为了研究在肠部PKCα抑制肿瘤的机制,采用了Santa Cruz Biotechnology公司的抗PKCδ抗体,进行了蛋白质印迹实验。 更多
PKC epsilon
protein kinase C epsilon
总数:20
GABAA receptor trafficking is regulated by protein kinase C(epsilon) and the N-ethylmaleimide-sensitive factor. 2010 至该文献
为了研究NSF和PKC epsilon能够调节GABAA受体转运来影响突触抑制,采用Santa Cruz Biotechnology的山羊抗PKC epsilon抗体进行蛋白印迹和免疫细胞化学实验。 更多
血小板活化因子受体 (platelet activating factor receptor)
总数:1
Relative levels of semen platelet activating factor-receptor (PAFr) and ubiquitin in yearling bulls with high content of semen white blood cells: implications for breeding soundness evaluation. 2007 至该文献
为研究血小板活化因子(PAF)受体在生育中的作用,采用Cayman 公司生产的 PAF受体抗体用于免疫印迹和免疫细胞化学实验。
PLCB2
phospholipase C beta 2
总数:3
Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx. 2005 至该文献
PRKCH
protein kinase C eta
总数:5
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 至该文献
为了证明CCL2通过Rho/PKCalpha信号通道相互作用引起脑内皮的通透性过高,使用了Cell Signaling Technology公司的抗磷酸-PKC-eta抗体,进行了免疫印迹实验。 更多
PRKCQ
protein kinase C theta
总数:10
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 至该文献
为了证明CCL2通过Rho/PKCalpha信号通道相互作用引起脑内皮的通透性过高,使用了Cell Signaling Technology公司的抗磷酸-PKC-theta抗体,进行了免疫印迹实验。 更多
PROK1
prokineticin 1
总数:1
The endocrine-gland-derived vascular endothelial growth factor (EG-VEGF)/prokineticin 1 and 2 and receptor expression in human prostate: Up-regulation of EG-VEGF/prokineticin 1 with malignancy. 2006 至该文献
PROKR1
prokineticin receptor 1
总数:1
Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway. 2010 至该文献
为了研究PROK1通过PROKR1和calcineurin/NFAT信号通路对IL11表达的调节,采用了Lifespan Biosciences的抗PROKR1抗体进行免疫组织化学实验。
PTGFR
prostaglandin F receptor
总数:1
Uteroglobin inhibits prostaglandin F2alpha receptor-mediated expression of genes critical for the production of pro-inflammatory lipid mediators. 2005 至该文献
QRFPR
pyroglutamylated RFamide peptide receptor
P物质 (substance P)
tachykinin precursor 1
总数:2
High affinity choline transporter immunoreactivity in rat ileum myenteric nerves. 2007 至该文献
为了集中鼠回肠神经系统中CHT免疫反应性和确定它是否colocalised与免疫反应性胆碱能,tachykinergic和硝基能电路系统的标记,使用了Santa Cruz公司的羊P物质抗体,进行了免疫组织化学实验。 更多
TACR1
tachykinin receptor 1
总数:4
Elimination of rat spinal substance P receptor bearing neurons dissociates cardiovascular and nocifensive responses to nicotinic agonists. 2008 至该文献
Chemicon的抗肽物质受体(NK-1r)抗体(1:1000)被用于免疫组织化学实验,来进一步研究烟碱激动剂囊内特征。 更多
TRIO
trio Rho guanine nucleotide exchange factor
TRPC3
transient receptor potential cation channel subfamily C member 3
总数:6
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 至该文献
TRPC6
transient receptor potential cation channel subfamily C member 6
总数:7
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 至该文献
TRPC7
transient receptor potential cation channel subfamily C member 7
总数:1
Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells. 2005 至该文献