G1/S Transition
基因
试剂
文献样例
产品评述样例
CCNA1
cyclin A1
总数:14
CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase. 2009 至该文献
使用Santa Cruz生物公司的抗cyclin A抗体进行免疫印迹来研究细胞周期过程中调钙素调节Ect2, MgcRacGAP, 和 MKLP1 表达的作用 更多
CCNE2
cyclin E2
总数:4
Polycomb protein SCML2 regulates the cell cycle by binding and modulating CDK/CYCLIN/p21 complexes. 2013 至该文献
为了研究 CYCE2 与SCML2之间的相互作用，采用Epitomics 公司的CYCE2 抗体进行western Blot 检测。 更多
CCNH
cyclin H
总数:3
Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor. 2005 至该文献
为研究人牙本质基质蛋白1(Dmp1)在Ras-Raf-Arf信号通路传导中的作用，采用Santa Cruz生产的cyclin H抗体用于免疫印迹实验。 更多
Cdc2
cyclin dependent kinase 1
总数:52
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献
为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用，采用了Santa Cruz的抗人Cdk1抗体进行免疫印迹实验。 更多
CDC25A
cell division cycle 25A
总数:10
Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways. 2009 至该文献
为了说明肿瘤坏死因子相关凋亡诱导配体可以通过将组蛋白H2AX和Chk2磷酸化来激活DNA损伤反应，使用了Santa Cruz Biotechnology公司的抗Cdc25A抗体进行蛋白印迹实验。 更多
CDC45
cell division cycle 45
CDC6
cell division cycle 6
总数:9
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献
为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用，采用了Santa Cruz的抗人Cdc6抗体进行免疫沉淀实验。 更多
CDC7
cell division cycle 7
总数:1
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. 2006 至该文献
CDK2
cyclin dependent kinase 2
总数:53
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献
为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用，采用了Santa Cruz的抗人Cdk2抗体进行免疫印迹实验。 更多
cdk7
cyclin dependent kinase 7
总数:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 至该文献
为了研究即刻早期反应基因表达调控因MED23突变而被破坏并导致智力障碍，采用Santa Cruz的多抗CDK7抗体进行ChIP和蛋白印迹实验。 更多
CDT1
chromatin licensing and DNA replication factor 1
总数:3
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 至该文献
为了说明Skp2参与非p19Arf-p53途径的细胞衰老，使用了Proteintech Group公司的Cdt1抗体来进行免疫印记实验。 更多
CKS1B
CDC28 protein kinase regulatory subunit 1B
总数:1
Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. 2005 至该文献
Cul1
cullin 1
总数:12
Mediator acts upstream of the transcriptional activator Gal4. 2012 至该文献
为了研究Mediator复合物是如何起始Gal4基因转录的，采用了Abcam公司的抗Cul1抗体进行了免疫共沉淀实验。 更多
周期一 (cyclin A)
cyclin A2
总数:39
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 至该文献
为了研究Pcid2通过调控MAD2表达在B细胞生存中发挥的决定性作用，采用了Santa Cruz Biotechnology公司的抗cyclin A单克隆抗体进行免疫印迹试验。 更多
细胞周期蛋白B1 (cyclin B1)
总数:64
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 至该文献
为了研究Pcid2通过调控MAD2表达在B细胞生存中发挥的决定性作用，采用了Thermo Fisher Scientific公司的抗cyclin B1单克隆抗体进行免疫印迹试验。 更多
周期蛋白E (cyclin E)
cyclin E1
总数:55
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 至该文献
为了研究在管腔乳腺癌中雌激素敏感性以及抗雌激素抗性的获得，采用了Santa Cruz 的抗cyclin E 抗体进行了western blot实验。 更多
DBF4
DBF4 zinc finger
dihydrofolate reductase
总数:1
Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment. 2005 至该文献
E2F1
E2F transcription factor 1
总数:37
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 至该文献
为了说明Skp2参与非p19Arf-p53途径的细胞衰老，使用了Santa Cruz公司的E2F1抗体来进行免疫印记实验。 更多
FBXO5
F-box protein 5
gankyrin
proteasome 26S subunit, non-ATPase 10
MCM10
minichromosome maintenance 10 replication initiation factor
MCM2
minichromosome maintenance complex component 2
总数:8
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. 2006 至该文献
MCM3
minichromosome maintenance complex component 3
总数:5
Orc1 controls centriole and centrosome copy number in human cells. 2009 至该文献
为了说明人类细胞中的中心体和中心粒的拷贝数是由Orc1调控的，使用了Santa Cruz Biotechnology公司的兔多克隆抗MCM3抗体进行蛋白印迹实验。 更多
MCM4
minichromosome maintenance complex component 4
总数:1
The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. 2010 至该文献
为了研究ETG1在调控内源性DNA应激中的作用，使用了Acbam公司的抗MCM4抗体，进行了免疫印迹实验。
MCM5
minichromosome maintenance complex component 5
总数:2
The DNA replication factor MCM5 is essential for Stat1-mediated transcriptional activation. 2005 至该文献
MCM6
minichromosome maintenance complex component 6
总数:2
The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. 2010 至该文献
为了研究ETG1在调控内源性DNA应激中的作用，使用了Acbam公司的抗MCM6抗体，进行了免疫印迹实验。 更多
MCM7
minichromosome maintenance complex component 7
总数:6
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献
为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用，采用了Santa Cruz的抗人Mcm7抗体进行免疫印迹实验。 更多
MCM8
minichromosome maintenance 8 homologous recombination repair factor
MNAT1
MNAT1 component of CDK activating kinase
总数:2
Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". 2006 至该文献
ORC1
origin recognition complex subunit 1
总数:1
p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation. 2005 至该文献
ORC2
origin recognition complex subunit 2
总数:7
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献
为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用，采用了Santa Cruz的抗人Orc2抗体进行免疫印迹实验。 更多
ORC3
origin recognition complex subunit 3
ORC4
origin recognition complex subunit 4
总数:1
Orc1 controls centriole and centrosome copy number in human cells. 2009 至该文献
为了说明人类细胞中的中心体和中心粒的拷贝数是由Orc1调控的，使用了Abcam公司的羊多克隆抗Orc4抗体进行蛋白印迹实验。
ORC5
origin recognition complex subunit 5
ORC6
origin recognition complex subunit 6
p21
cyclin dependent kinase inhibitor 1A
总数:178
Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1. 2012 至该文献
为了研究阿霉素抑制肿瘤生长的机制，采用了Abcam的兔抗p21抗体，进行免疫印迹实验。 更多
p27
cyclin dependent kinase inhibitor 1B
总数:118
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. 2012 至该文献
为了研究p53依赖的细胞增殖和存活能够被atg7调控，采用了BD Pharmingen的抗p27CDKN1B抗体进行蛋白印迹实验。 更多
p44S10
proteasome 26S subunit, non-ATPase 6
增殖细胞核抗原 (PCNA)
proliferating cell nuclear antigen
总数:84
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 至该文献
为了研究DNA损伤应答过程中RHINO对ATR活化的重要作用，采用Santa Cruz的抗PCNA抗体进行蛋白印迹实验。 更多
PKMYT1
protein kinase, membrane associated tyrosine/threonine 1
POLA1
DNA polymerase alpha 1, catalytic subunit
总数:1
p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum. 2012 至该文献
为了研究p180对一些能够不依赖核糖体实现在内质网上定位的mRNA的作用，采用了Sigma公司的抗p180抗体进行免疫印迹试验。
POLA2
DNA polymerase alpha 2, accessory subunit
POLE
DNA polymerase epsilon, catalytic subunit
POLE2
DNA polymerase epsilon 2, accessory subunit
PP2AC
protein phosphatase 2 catalytic subunit alpha
总数:20
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 至该文献
PPP2CB
protein phosphatase 2 catalytic subunit beta
PPP2R1A
protein phosphatase 2 scaffold subunit Aalpha
总数:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 至该文献
PPP2R1B
protein phosphatase 2 scaffold subunit Abeta
总数:2
SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process. 2007 至该文献
为了研究sk1的功能，采用了Sigma-Aldrich公司的单克隆抗PP2A抗体，进行了蛋白印记实验。 更多
PPP2R3B
protein phosphatase 2 regulatory subunit B''beta
PRIM2
DNA primase subunit 2
PSMA1
proteasome 20S subunit alpha 1
总数:9
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 至该文献
PSMA3
proteasome 20S subunit alpha 3
总数:3
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 至该文献
为了研究内着丝粒是如何建立的和CPC复合物是如何靶向到此位点的机制，使用了Santa Cruz Biotechnology公司的抗Psc3抗体来进行染色质免疫沉淀实验。 更多
PSMA4
proteasome 20S subunit alpha 4
总数:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献
为了研究免疫蛋白酶体在多发性硬化发病机制的作用，采用Affinity-Biomol International小鼠抗人的20S proteasome subunit alpha4单克隆抗体进行免疫组织化学试验。 更多
PSMA7
proteasome 20S subunit alpha 7
总数:4
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 至该文献
为了在内质网相关蛋白的降解途径（ERAD）中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能，使用了Enzo Life Sciences公司的抗体alpha7来进行免疫印迹分析。 更多
PSMB1
proteasome 20S subunit beta 1
总数:2
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体亚基β1抗体,进行了蛋白质印迹实验. 更多
PSMB10
proteasome 20S subunit beta 10
PSMB4
proteasome 20S subunit beta 4
PSMB5
proteasome 20S subunit beta 5
总数:1
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体亚基β5抗体,进行了蛋白质印迹实验.
PSMB6
proteasome 20S subunit beta 6
PSMB7
proteasome 20S subunit beta 7
PSMB8
proteasome 20S subunit beta 8
总数:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献
为了研究免疫蛋白酶体在多发性硬化发病机制的作用，采用Affinity-Biomol International抗LMP7抗体进行免疫组织化学试验。 更多
PSMB9
proteasome 20S subunit beta 9
总数:2
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献
为了研究免疫蛋白酶体在多发性硬化发病机制的作用，采用Affinity-Biomol International抗LMP2抗体进行免疫组织化学试验。 更多
PSMC1
proteasome 26S subunit, ATPase 1
PSMC4
proteasome 26S subunit, ATPase 4
总数:8
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 至该文献
为了研究在帕金森疾病模型中雷怕霉素对神经元的保护作用，采用了Cell Signaling Technology的抗phospho-Ser235/236-S6抗体进行免疫细胞化学试验。 更多
PSMC6
proteasome 26S subunit, ATPase 6
总数:1
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 至该文献
PSMD1
proteasome 26S subunit, non-ATPase 1
PSMD11
proteasome 26S subunit, non-ATPase 11
PSMD12
proteasome 26S subunit, non-ATPase 12
PSMD13
proteasome 26S subunit, non-ATPase 13
PSMD14
proteasome 26S subunit, non-ATPase 14
PSMD2
proteasome 26S subunit, non-ATPase 2
总数:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 至该文献
为了说明hHR23A介导的Vpr与蛋白酶体的互作在病毒复制过程中有重要作用，使用了Calbiochem公司的19S蛋白酶体S2亚基的兔多抗来进行免疫印记实验。
PSMD4
proteasome 26S subunit, non-ATPase 4
总数:3
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 至该文献
为了说明hHR23A介导的Vpr与蛋白酶体的互作在病毒复制过程中有重要作用，使用了Calbiochem公司的19S蛋白酶体S5a亚基的兔多抗来进行免疫印记实验。 更多
PSMD5
proteasome 26S subunit, non-ATPase 5
PSMD7
proteasome 26S subunit, non-ATPase 7
PSMD8
proteasome 26S subunit, non-ATPase 8
PSMD9
proteasome 26S subunit, non-ATPase 9
总数:13
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 至该文献
为了研究在管腔乳腺癌中雌激素敏感性以及抗雌激素抗性的获得，采用了Santa Cruz 的抗p27抗体进行了western blot实验。 更多
PSME1
proteasome activator subunit 1
总数:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献
为了研究免疫蛋白酶体在多发性硬化中的作用，采用Affinity-Biomol International兔抗PA28alpha多克隆抗体进行免疫组织化学试验。 更多
PSME2
proteasome activator subunit 2
总数:1
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 至该文献
为了确认长期酒精喂养对蛋白酶体相互作用蛋白表达的影响，采用了BIOMOL公司的抗PA28β抗体进行免疫印迹法实验。
PSME3
proteasome activator subunit 3
PSMF1
proteasome inhibitor subunit 1
Rb
RB transcriptional corepressor 1
总数:77
LIMD1 is more frequently altered than RB1 in head and neck squamous cell carcinoma: clinical and prognostic implications. 2010 至该文献
为了研究LIMD1和pRB两个蛋白在头颈鳞状细胞癌中的作用，采用了Santa Cruz的兔抗pRB的多克隆IgG抗体进行免疫组织化学试验。 更多
RPA2
replication protein A2
总数:12
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. 2010 至该文献
为了研究人类I性单纯疱疹病毒感染细胞中，病毒基因表达和复制过程中ATR和ATRIP两者的关系，采用了GeneTex的抗RPA32单克隆抗体进行了细胞免疫荧光实验。 更多
RPS27A
ribosomal protein S27a
总数:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 至该文献
为了在内质网相关蛋白的降解途径（ERAD）中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能，使用了Santa Cruz Biotechnology公司的抗体ubiquitin来进行免疫印迹分析。 更多
RRM2
ribonucleotide reductase regulatory subunit M2
S3
proteasome 26S subunit, non-ATPase 3
Skp1
S-phase kinase associated protein 1
总数:8
APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. 2009 至该文献
Skp2
S-phase kinase associated protein 2
总数:17
Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy. 2009 至该文献
为了在K562细胞中研究CSN对细胞自噬有重要作用，采用Zymed的抗Skp2抗体以1:1000稀释进行蛋白印迹实验。 更多
TFDP1
transcription factor Dp-1
总数:1
Identification and characterization of novel isoforms of human DP-1: DP-1{alpha} regulates the transcriptional activity of E2F1 as well as cell cycle progression in a dominant-negative manner. 2005 至该文献
TK2
thymidine kinase 2
UBC
ubiquitin C
总数:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 至该文献
为了研究突触的可塑性，采用了Enzo Life Sciences的抗Ubiquitin的抗体进行了免疫印迹实验。 更多
泛肽 (ubiquitin)
ubiquitin B
总数:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 至该文献
为了阐明BCL6和HB-EGF-CTF相互作用，并且这种相互作用可能会引起细胞周期蛋白D2在人胃癌细胞中表达，采用了Cell Signaling Technology公司的小鼠抗泛素单克隆抗体，进行了蛋白质印迹实验。 更多
WEE1
WEE1 G2 checkpoint kinase
总数:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 至该文献
为了研究FANCM在有丝分裂过程中的降解机制，使用了Santa Cruz Biotechnology公司的兔抗WEE1抗体来进行免疫印迹分析。 更多