G2/M Checkpoints
基因
试剂
文献样例
产品评述样例
毛细血管扩张性共济失调症突变蛋白 (ATM)
ATM serine/threonine kinase
总数:50
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 至该文献
为了检测CENPS/MHF1、CENPX/MHF2、FANCD以及 FANCI募集到离子辐射损伤部位需要 RSF1分子,采用 Millipore 公司的phospho-ATM-S1981抗体进行免疫荧光实验。 更多
ATR
ATR serine/threonine kinase
总数:24
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 至该文献
为了研究 RSFI在DNA 双链断裂修复过程中需要 RSF1分子,采用 Santa Cruz公司的 ATR 抗体进行细胞免疫荧光实验。 更多
ATRIP
ATR interacting protein
总数:1
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. 2010 至该文献
为了研究人类I性单纯疱疹病毒感染细胞中,病毒基因表达和复制过程中ATR和ATRIP两者的关系,采用了R&D的抗ATRIP抗体进行了免疫印迹实验和细胞免疫荧光实验。
CCNB2
cyclin B2
总数:1
Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control. 2007 至该文献
Cdc2
cyclin dependent kinase 1
总数:52
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献
为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用,采用了Santa Cruz的抗人Cdk1抗体进行免疫印迹实验。 更多
CDC25A
cell division cycle 25A
总数:10
Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways. 2009 至该文献
为了说明肿瘤坏死因子相关凋亡诱导配体可以通过将组蛋白H2AX和Chk2磷酸化来激活DNA损伤反应,使用了Santa Cruz Biotechnology公司的抗Cdc25A抗体进行蛋白印迹实验。 更多
cdc25C
cell division cycle 25C
总数:20
Chk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growth.. 2008 至该文献
为了研究Chk2在调控HSV-1 ICP0介导的G2/M期阻滞和病毒生长中的作用,采用Epitomics公司的抗ATM抗体产品,进行了免疫印迹实验。 更多
CDC6
cell division cycle 6
总数:9
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献
为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用,采用了Santa Cruz的抗人Cdc6抗体进行免疫沉淀实验。 更多
CDC7
cell division cycle 7
总数:1
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. 2006 至该文献
CDK2
cyclin dependent kinase 2
总数:53
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献
为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用,采用了Santa Cruz的抗人Cdk2抗体进行免疫印迹实验。 更多
Chk1
checkpoint kinase 1
总数:59
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. 2010 至该文献
为了研究人类I性单纯疱疹病毒感染细胞中,病毒基因表达和复制过程中ATR和ATRIP两者的关系,采用了Santa Cruz的抗Chk1单克隆抗体进行了免疫印迹实验。 更多
CHK2
checkpoint kinase 2
总数:48
Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. 2011 至该文献
为了研究染色体结构异常可由染色体分离错误引起,采用了Santa Cruz的抗chk2抗体进行蛋白印迹和免疫细胞化学实验。 更多
CLSPN
claspin
总数:6
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 至该文献
为了研究FANCM在有丝分裂过程中的降解机制,使用了Bethyl Laboratories的兔抗Claspin抗体来进行免疫印迹分析。 更多
细胞周期蛋白B1 (cyclin B1)
总数:64
Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 至该文献
为了研究Pcid2通过调控MAD2表达在B细胞生存中发挥的决定性作用,采用了Thermo Fisher Scientific公司的抗cyclin B1单克隆抗体进行免疫印迹试验。 更多
HUS1
HUS1 checkpoint clamp component
总数:1
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 至该文献
为了研究DNA损伤应答过程中RHINO对ATR活化的重要作用,采用Santa Cruz的抗Hus1抗体进行蛋白印迹实验。
MCM10
minichromosome maintenance 10 replication initiation factor
MCM2
minichromosome maintenance complex component 2
总数:8
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. 2006 至该文献
MCM3
minichromosome maintenance complex component 3
总数:5
Orc1 controls centriole and centrosome copy number in human cells. 2009 至该文献
为了说明人类细胞中的中心体和中心粒的拷贝数是由Orc1调控的,使用了Santa Cruz Biotechnology公司的兔多克隆抗MCM3抗体进行蛋白印迹实验。 更多
MCM4
minichromosome maintenance complex component 4
总数:1
The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. 2010 至该文献
为了研究ETG1在调控内源性DNA应激中的作用,使用了Acbam公司的抗MCM4抗体,进行了免疫印迹实验。
MCM5
minichromosome maintenance complex component 5
总数:2
The DNA replication factor MCM5 is essential for Stat1-mediated transcriptional activation. 2005 至该文献
MCM6
minichromosome maintenance complex component 6
总数:2
The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. 2010 至该文献
为了研究ETG1在调控内源性DNA应激中的作用,使用了Acbam公司的抗MCM6抗体,进行了免疫印迹实验。 更多
MCM7
minichromosome maintenance complex component 7
总数:6
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献
为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用,采用了Santa Cruz的抗人Mcm7抗体进行免疫印迹实验。 更多
MCM8
minichromosome maintenance 8 homologous recombination repair factor
ORC1
origin recognition complex subunit 1
总数:1
p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation. 2005 至该文献
ORC2
origin recognition complex subunit 2
总数:7
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献
为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用,采用了Santa Cruz的抗人Orc2抗体进行免疫印迹实验。 更多
ORC3
origin recognition complex subunit 3
ORC4
origin recognition complex subunit 4
总数:1
Orc1 controls centriole and centrosome copy number in human cells. 2009 至该文献
为了说明人类细胞中的中心体和中心粒的拷贝数是由Orc1调控的,使用了Abcam公司的羊多克隆抗Orc4抗体进行蛋白印迹实验。
ORC5
origin recognition complex subunit 5
PKMYT1
protein kinase, membrane associated tyrosine/threonine 1
RAD1
RAD1 checkpoint DNA exonuclease
总数:2
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 至该文献
为了研究DNA损伤应答过程中RHINO对ATR活化的重要作用,采用Novus Biologicals的抗Rad1抗体进行蛋白印迹实验。 更多
Rad17
RAD17 checkpoint clamp loader component
总数:7
Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway. 2010 至该文献
为了研究MutSalpha 和MutLalpha在调控ATR-Chk1信号通路中的作用,采用了Bethyl Laboratories公司的抗Rad17抗体产品,进行了免疫印迹实验。 更多
Rad9
RAD9 checkpoint clamp component A
总数:7
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 至该文献
为了研究DNA损伤应答过程中RHINO对ATR活化的重要作用,采用Bethyl的抗Rad9抗体进行蛋白印迹实验。 更多
RPA2
replication protein A2
总数:12
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. 2010 至该文献
为了研究人类I性单纯疱疹病毒感染细胞中,病毒基因表达和复制过程中ATR和ATRIP两者的关系,采用了GeneTex的抗RPA32单克隆抗体进行了细胞免疫荧光实验。 更多
WEE1
WEE1 G2 checkpoint kinase
总数:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 至该文献
为了研究FANCM在有丝分裂过程中的降解机制,使用了Santa Cruz Biotechnology公司的兔抗WEE1抗体来进行免疫印迹分析。 更多