组蛋白赖氨酸的N-甲基转移酶
基因
试剂
文献样例
产品评述样例
ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
CLLD8
SET domain, bifurcated 2
总数:1
Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. 2008 至该文献
为了研究HIV-1的Tat蛋白赖氨酸甲基化在病毒LTR转录活性中的作用，采用了Abgent的抗人SETDB2抗体进行免疫印迹实验。
DOT1L
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
总数:2
DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. 2008 至该文献
为了研究在人HEK293T细胞中DOT1L的重组和H3K79的单、双或者三甲基化的动态状态， 采用了Bethyl公司的抗DOT1L 抗体(A300-954A or 953A)进行ChIP分析 更多
EHMT1
euchromatic histone-lysine N-methyltransferase 1
EHMT2
euchromatic histone-lysine N-methyltransferase 2
总数:3
ZNF274 Recruits the Histone Methyltransferase SETDB1 to the 3' Ends of ZNF Genes. 2010 至该文献
为了说明包含ZNF的KRAB结构域参与了招募KAP1和SETDB1到人类基因组中特定区段的过程，使用了Upstate公司的G9a抗体(#07-551)来进行ChIP实验。 更多
EZH1
enhancer of zeste homolog 1 (Drosophila)
Ezh2
enhancer of zeste homolog 2 (Drosophila)
总数:11
Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma. 2005 至该文献
为了检测EZH2在肝癌病人体内的表达，采用ABGENT的多克隆EZH2抗体进行免疫组化实验。 更多
MLL
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
总数:2
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 至该文献
为了阐明c-Myb在MLL相关白血病中的作用，实验使用了Upstate Biotechnology公司的抗MLL抗体进行免疫共沉淀。 更多
MLL2
myeloid/lymphoid or mixed-lineage leukemia 2
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
MLL4
myeloid/lymphoid or mixed-lineage leukemia 4
MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
NSD1
nuclear receptor binding SET domain protein 1
PRDM6
PR domain containing 6
PRDM7
PR domain containing 7
PRDM9
PR domain containing 9
RIZ
PR domain containing 2, with ZNF domain
总数:2
RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression. 2009 至该文献
为了研究RIZ1在慢性髓性白血病从慢性期到急变期过程中的下调表达，使用了Abgent公司的RIZ1抗体来进行蛋白印迹实验、流式细胞术检测和免疫组化实验。 更多
Set1
SET domain containing 1A
总数:1
CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. 2005 至该文献
SETD1B
SET domain containing 1B
SETD2
SET domain containing 2
SETD3
SET domain containing 3
SETD7
SET domain containing (lysine methyltransferase) 7
总数:5
Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells. 2009 至该文献
为了研究DNMT1稳定性在哺乳动物细胞中的调节作用，研究中使用了CST公司的抗赖氨酸甲基转移酶7抗体来对海拉细胞的和提取物进行免疫沉淀反应。 更多
SETD8
SET domain containing (lysine methyltransferase) 8
总数:1
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. 2008 至该文献
为了研究FoxA1在乳腺癌和前列腺癌细胞中差异转录活性和这些细胞表观基因组学功能相关性，采用了Abcam 公司的抗H4K20me1, me2, me3抗体(Ab9051, Ab9052 and Ab9053)进行ChIP分析
SETDB1
SET domain, bifurcated 1
总数:4
ZNF274 Recruits the Histone Methyltransferase SETDB1 to the 3' Ends of ZNF Genes. 2010 至该文献
为了说明包含ZNF的KRAB结构域参与了招募KAP1和SETDB1到人类基因组中特定区段的过程，使用了Proteintech Group公司的SETDB1抗体(#11231-1-AP)来进行ChIP实验。 更多
SETMAR
SET domain and mariner transposase fusion gene
总数:1
Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. 2008 至该文献
为了研究HIV-1的Tat蛋白赖氨酸甲基化在病毒LTR转录活性中的作用，采用了Abcam的抗人SETMAR抗体进行免疫印迹实验。
SMYD2
SET and MYND domain containing 2
SMYD3
SET and MYND domain containing 3
SUV39H1
suppressor of variegation 3-9 homolog 1 (Drosophila)
总数:7
On the mechanism of induction of heterochromatin by the RNA-binding protein vigilin. 2008 至该文献
SUV39H2
suppressor of variegation 3-9 homolog 2 (Drosophila)
SUV420H1
suppressor of variegation 4-20 homolog 1 (Drosophila)
SUV420H2
suppressor of variegation 4-20 homolog 2 (Drosophila)
WHSC1
Wolf-Hirschhorn syndrome candidate 1
WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1