Interleukin-1 signaling
基因
试剂
文献样例
产品评述样例
ABIN 2 (ABIN 2)
TNFAIP3 interacting protein 2
总数:1
Proteomics analysis of immunoprecipitated proteins associated with the oncogenic kinase cot. 2008 至该文献
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
总数:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 至该文献
为了研究FANCM在有丝分裂过程中的降解机制，使用了Zymed Laboratories的小鼠抗β-TRCP抗体来进行免疫印迹分析。 更多
Cul1
cullin 1
总数:12
Mediator acts upstream of the transcriptional activator Gal4. 2012 至该文献
为了研究Mediator复合物是如何起始Gal4基因转录的，采用了Abcam公司的抗Cul1抗体进行了免疫共沉淀实验。 更多
IKK甲 (IKK alpha)
component of inhibitor of nuclear factor kappa B kinase complex
总数:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 至该文献
为了研究切割的NIK 导致非经典的NF- kB 活性 ，采用了Santa Cruz Biotechnology的抗IKKα抗体进行免疫印迹实验。 更多
IKKbeta
inhibitor of nuclear factor kappa B kinase subunit beta
总数:36
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 至该文献
为了研究人类IKK2激活的结构基础,Millipore的抗IKK2抗体被用于进行蛋白质免疫印迹实验。 更多
IKKgamma
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
总数:21
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 至该文献
为了研究人类IKK2激活的结构基础,Santa Cruz Biotechnology的抗NEMO抗体被用于进行蛋白质免疫印迹实验。 更多
IL-1beta (IL-1beta)
interleukin 1 beta
总数:30
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 至该文献
为了研究IL-26诱导促炎因子的分泌和促进Th17细胞的产生，采用了R&D Systems公司的抗IL-1-beta抗体进行细胞刺激。 更多
IL1A
interleukin 1 alpha
总数:5
Intracellular IL-1alpha-binding proteins contribute to biological functions of endogenous IL-1alpha in systemic sclerosis fibroblasts. 2006 至该文献
IL1R1
interleukin 1 receptor type 1
总数:5
Control of chemokine gradients by the retinal pigment epithelium. 2008 至该文献
IL1R2
interleukin 1 receptor type 2
总数:2
Stable inhibition of interleukin 1 receptor type II in Ishikawa cells augments secretion of matrix metalloproteinases: possible role in endometriosis pathophysiology. 2007 至该文献
为研究白介素1受体2(IL1R2)表达缺失对子宫内膜异位症的作用，采用R&D公司生产的羊源性IL1RAcP多克隆抗体用于免疫印迹和免疫细胞化学实验。 更多
IL1RAP
interleukin 1 receptor accessory protein
总数:2
Stable inhibition of interleukin 1 receptor type II in Ishikawa cells augments secretion of matrix metalloproteinases: possible role in endometriosis pathophysiology. 2007 至该文献
为研究白介素1受体2(IL1R2)表达缺失对子宫内膜异位症的作用，采用R&D公司生产的羊源性IL1RAcP多克隆抗体用于免疫印迹实验。 更多
IL1RN
interleukin 1 receptor antagonist
总数:1
Beta-(1-->3)-D-glucan modulates DNA binding of nuclear factors kappaB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1beta/IL-1 receptor antagonist ratio. 2006 至该文献
IRAK
interleukin 1 receptor associated kinase 1
总数:10
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 至该文献
为了研究IRAK-1信号阻断对TLR2和TLR4诱导的人树突状细胞耐受有重要作用，采用Santa Cruz的鼠抗IRAK-1抗体进行蛋白印迹实验。 更多
IRAK4
interleukin 1 receptor associated kinase 4
总数:2
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 至该文献
为了研究IRAK-1信号阻断对TLR2和TLR4诱导的人树突状细胞耐受有重要作用，采用Biomol的兔抗IRAK-4抗体进行蛋白印迹实验。 更多
MAP3K8
mitogen-activated protein kinase kinase kinase 8
总数:4
Proteomics analysis of immunoprecipitated proteins associated with the oncogenic kinase cot. 2008 至该文献
MEK1
mitogen-activated protein kinase kinase 1
总数:57
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 至该文献
为了研究在气喘患者中由TGFbeta和IL-10抑制造成的对T细胞的抗性的信号传导机制，采用了Cell Signaling Technology的抗MEK1抗体进行了流式细胞实验和免疫组化检测。 更多
MKK6
mitogen-activated protein kinase kinase 6
总数:9
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia. 2008 至该文献
为了阐述ATM经历了一个由复杂的包膜糖蛋白在体外（环境）的人类免疫缺陷病毒1（HIV-1）引起合胞体激活磷酸化，采用了细胞信号技术公司的多克隆大鼠MKK6抗体进行了蛋白印迹实验。 更多
MYD88
MYD88 innate immune signal transduction adaptor
总数:3
Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state. 2008 至该文献
为了研究1型糖尿病人单核细胞中TLR2和TLR4的表达，采用eBiosciences公司兔抗MyD88抗体进行免疫印迹实验。 更多
NOD1
nucleotide binding oligomerization domain containing 1
NOD2
nucleotide binding oligomerization domain containing 2
总数:2
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. 2006 至该文献
p50
nuclear factor kappa B subunit 1
总数:81
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 至该文献
为了说明流感病毒感染期间IL-32表达水平的提高抑制病毒的复制，使用了Santa Cruz Biotechnology公司的anti-p50抗体来进行染色质免疫共沉淀实验。 更多
PELI1
pellino E3 ubiquitin protein ligase 1
PELI2
pellino E3 ubiquitin protein ligase family member 2
PELI3
pellino E3 ubiquitin protein ligase family member 3
RBX1
ring-box 1
总数:5
Poxvirus ankyrin repeat proteins are a unique class of F-box proteins that associate with cellular SCF1 ubiquitin ligase complexes. 2008 至该文献
Skp1
S-phase kinase associated protein 1
总数:8
APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. 2009 至该文献
泛肽结合蛋白p62 (SQSTM1)
sequestosome 1
总数:14
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 至该文献
为了研究具有分解代谢功能的细胞器和具有合成代谢功能的细胞器二者在空间上的结合在促进分泌蛋白合成中的作用，采用Santa Cruz的抗p62抗体进行免疫细胞化学试验。 更多
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1
总数:5
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 至该文献
为了研究NRAGE在调节NF-kappaB活性时所发挥的作用，采用了Santa Cruz的羊抗Tab1抗体进行蛋白质印迹试验。 更多
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2
总数:2
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 至该文献
为了研究在B细胞中TNIK在经典的NF-kB和JNK通路中扮演何种角色及如何发挥这种作用，采用了Santa Cruz Biotechnology的TAB2抗体进行免疫印迹实验。 更多
TAB3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3
Tak1
mitogen-activated protein kinase kinase kinase 7
总数:10
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 至该文献
为了研究NRAGE在调节NF-kappaB活性时所发挥的作用，采用了Santa Cruz的小鼠抗Tak1抗体进行蛋白质印迹试验。 更多
TMEM189-UBE2V1 (TMEM189-UBE2V1)
TMEM189-UBE2V1 readthrough
TOLLIP
toll interacting protein
TRAF6
TNF receptor associated factor 6
总数:17
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 至该文献
为了研究在B细胞中TNIK在经典的NF-kB和JNK通路中扮演何种角色及如何发挥这种作用，采用了Santa Cruz Biotechnology的TRAF6 (H-274)抗体进行免疫印迹实验。 更多
UBE2N
ubiquitin conjugating enzyme E2 N
总数:3
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 至该文献
为了研究DNA损伤应答过程中RHINO对ATR活化的重要作用，采用Invitrogen的抗Ubc13抗体进行蛋白印迹实验。 更多