非特异性丝氨酸/苏氨酸蛋白激酶
基因
试剂
文献样例
产品评述样例
AIM-1
aurora kinase B
总数:21
Two histone marks establish the inner centromere and chromosome bi-orientation.. 2010 至该文献
为了研究内着丝粒是如何建立的和CPC复合物是如何靶向到此位点的机制,使用了BD Biosciences公司的兔抗Aurora B多克隆抗体来进行免疫印迹分析和免疫荧光实验。 更多
Akt
v-akt murine thymoma viral oncogene homolog 1
总数:418
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H?-ATPase.. 2011 至该文献
为了研究泡状H+-ATPase参与到mTOR通路中mTORC1的转位和激活,采用Cell Signaling的抗Akt和抗S473磷酸化Akt抗体进行蛋白印迹实验。 更多
AKT2
v-akt murine thymoma viral oncogene homolog 2
总数:15
EGFR Signaling Through an Akt-SREBP-1-Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy. 2009 至该文献
为了研究表皮生长因子突变常常与肿瘤发生有关,研究了Akt介导的在表皮生长因子诱导下固醇调节结合蛋白1的切割以及移位机理,并发现了一种新的治疗由于表皮生长因子激活的胶质母细胞瘤,采用了Cell Signaling公司p-Akt丝氨酸473抗体,进行免疫化学荧光实验。 更多
AKT3
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
总数:4
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. 2008 至该文献
为了研究抑制Akt通路后PTEN缺失的肿瘤自噬增多,并对趋溶酶体剂更敏感,采用了Millipore的抗Akt3抗体进行免疫印迹实验。 更多
ANKK1
ankyrin repeat and kinase domain containing 1
ARAF
v-raf murine sarcoma 3611 viral oncogene homolog
总数:2
Trihydrophobin 1 is a new negative regulator of A-Raf kinase. 2004 至该文献
ARK5
NUAK family, SNF1-like kinase, 1
总数:1
Muscle contractions, AICAR, and insulin cause phosphorylation of an AMPK-related kinase. 2005 至该文献
毛细血管扩张性共济失调症突变蛋白 (ATM)
ataxia telangiectasia mutated
总数:49
Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations.. 2011 至该文献
为了研究染色体结构异常可由染色体分离错误引起,采用了Cell Signaling的抗1981位丝氨酸磷酸化ATM抗体进行免疫细胞化学实验。 更多
ATR
ataxia telangiectasia and Rad3 related
总数:23
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling.. 2011 至该文献
为了研究DNA损伤应答过程中RHINO对ATR活化的重要作用,采用Santa Cruz的抗ATR抗体进行蛋白印迹实验。 更多
AURKA
aurora kinase A
总数:16
Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer.. 2011 至该文献
Cell Signaling Technology的 抗AURKA抗体以免疫杂交的方法来研究其与RHAMM之间的关系。 更多
AURKC
aurora kinase C
总数:3
Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors. 2010 至该文献
为了研究主轴蛋白质在睾丸肿瘤生殖细胞生长过程中的不同表达水平,采用了Abgent公司极光激酶C抗体,进行蛋白质印记实验。 更多
B-Raf
v-raf murine sarcoma viral oncogene homolog B1
总数:8
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 至该文献
为了研究Raf-1对神经胶质瘤形成的作用,采用了Santa Cruz Biotechnology的抗Braf抗体进行免疫印迹实验。 更多
Bcr
breakpoint cluster region
总数:7
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. 2008 至该文献
为了研究Lyn调节慢性粒细胞白血病细胞对imatinib敏感性的机制,使用了Cell Signaling Technology公司的抗酪氨酸磷酸化BCR-ABL抗体来进行免疫印记分析。 更多
BUB1
budding uninhibited by benzimidazoles 1 homolog (yeast)
总数:2
Two histone marks establish the inner centromere and chromosome bi-orientation.. 2010 至该文献
为了研究内着丝粒是如何建立的和CPC复合物是如何靶向到此位点的机制,使用了Chemicon公司的小鼠抗Bub1单克隆抗体来进行免疫印迹分析。 更多
BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
总数:5
Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors. 2010 至该文献
为了研究主轴蛋白质在睾丸肿瘤生殖细胞生长过程中的不同表达水平,采用了BD Transduction Laboratories公司BUB1B抗体,进行蛋白质印记实验。 更多
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
总数:6
SUMOylation of the MAGUK protein CASK regulates dendritic spinogenesis. 2008 至该文献
为了研究树突棘的形成能够被MAGUK蛋白质CASK的SUMO化所调节,采用了Santa Cruz的兔多抗CASK抗体进行免疫印迹实验。 更多
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
CDC7
cell division cycle 7 homolog (S. cerevisiae)
总数:1
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. 2006 至该文献
Chk1
checkpoint kinase 1
总数:58
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling.. 2011 至该文献
为了研究DNA损伤应答过程中RHINO对ATR活化的重要作用,采用Cell Signaling的抗磷酸化S317-Chk1抗体进行蛋白印迹实验。 更多
CHK2
checkpoint kinase 2
总数:46
Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations.. 2011 至该文献
为了研究染色体结构异常可由染色体分离错误引起,采用了Cell Signaling的抗68位苏氨酸磷酸化chk2抗体进行蛋白印迹和免疫细胞化学实验。 更多
CIT
citron (rho-interacting, serine/threonine kinase 21)
总数:1
Focal adhesion components are essential for mammalian cell cytokinesis. 2008 至该文献
为了研究粘着因子在哺乳动物细胞胞质中的重要作用使用了Santa Cruz Biotechnology公司的citron K抗体来进行蛋白印迹实验。
CKI epsilon
casein kinase 1, epsilon
总数:5
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. 2009 至该文献
为了研究Akt1介导的Skp2的磷酸化引起的Skp2细胞质定位和对APCCdh1参与的Skp2降解的损害,采用了Abgent的抗CKI epsilon抗体进行免疫印迹实验。 更多
CSNK1A1
casein kinase 1, alpha 1
总数:5
Protein kinase CK1alpha regulates mRNA binding by heterogeneous nuclear ribonucleoprotein C in response to physiologic levels of hydrogen peroxide. 2005 至该文献
CSNK1D
casein kinase 1, delta
总数:1
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. 2009 至该文献
为了研究Akt1介导的Skp2的磷酸化引起的Skp2细胞质定位和对APCCdh1参与的Skp2降解的损害,采用了Santa Cruz的抗CKI delta抗体进行免疫印迹实验。
CSNK2A1
casein kinase 2, alpha 1 polypeptide
总数:9
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 至该文献
为了研究NF-kB转录因子在白介素1诱导的C/EBPδ和APP基因表达中的功能,使用了Santa Cruz Biotechnology公司的抗CK2 alpha抗体来进行免疫印迹分析。 更多
CSNK2A2
casein kinase 2, alpha prime polypeptide
总数:4
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 至该文献
为了研究NF-kB转录因子在白介素1诱导的C/EBPδ和APP基因表达中的功能,使用了Santa Cruz Biotechnology公司的抗CK2 alpha'抗体来进行免疫印迹分析。 更多
DAPK1
death-associated protein kinase 1
总数:2
A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK. 2002 至该文献
DAPK2
death-associated protein kinase 2
DMPK
dystrophia myotonica-protein kinase
总数:1
Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum. 2005 至该文献
DNA-PKcs
protein kinase, DNA-activated, catalytic polypeptide
总数:11
Adeno-associated virus replication induces a DNA damage response coordinated by DNA-dependent protein kinase. 2009 至该文献
为了研究腺相关病毒和腺病毒共感染对诱导细胞DNA损伤应答的影响,使用了NeoMarkers公司的抗DNA-PKcs抗体来进行免疫印迹分析和免疫荧光实验。 更多
EIF2AK1
eukaryotic translation initiation factor 2-alpha kinase 1
EIF2AK4
eukaryotic translation initiation factor 2 alpha kinase 4
总数:3
The role of nitric-oxide synthase in the regulation of UVB light-induced phosphorylation of the alpha subunit of eukaryotic initiation factor 2. 2009 至该文献
为了说明短波紫外线诱导的eIF2α磷酸化是受一氧化氮合酶(NOS)调节,使用了Abgent公司的兔抗体GCN2来进行免疫共沉淀分析。 更多
ERN1
endoplasmic reticulum to nucleus signaling 1
总数:2
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. 2006 至该文献
Santa Cruz Biotechnology的抗IRE1α抗体被用于蛋白质印迹实验,来研究ER激活NF-κB的机制,以及在人的细胞中NF-κB在调节ER介导的细胞死亡中的作用。 更多
ERN2
endoplasmic reticulum to nucleus signaling 2
GAK
cyclin G associated kinase
总数:1
The DnaJ-domain protein RME-8 functions in endosomal trafficking. 2005 至该文献
GSK3
glycogen synthase kinase 3 alpha
总数:22
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. 2009 至该文献
为了揭示在CXCL12诱发的T淋巴细胞迁移过程中CRMP2功能的分子机制,采用了Upstate公司的鼠抗pGSK3A(pTyr-279)抗体进行免疫印迹实验。 更多
GSK3beta
glycogen synthase kinase 3 beta
总数:75
Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma. 2010 至该文献
为了研究LMP2A在鼻咽癌进展中的作用,采用了Cell Signaling的抗GSK-3beta抗体进行了免疫印迹实验。 更多
haspin
germ cell associated 2 (haspin)
总数:2
Survivin Reads Phosphorylated Histone H3 Threonine 3 to Activate the Mitotic Kinase Aurora B.. 2010 至该文献
为了研究在有丝分裂过程中组蛋白高程度磷酸化的功能,使用了Invitrogen公司的包被抗Haspin抗体的磁珠来从CSF裂解液中除去Haspin蛋白。 更多
hematopoietic progenitor kinase 1
mitogen-activated protein kinase kinase kinase kinase 1
总数:3
Protein phosphatase 4 is a positive regulator of hematopoietic progenitor kinase 1. 2004 至该文献
HIPK3
homeodomain interacting protein kinase 3
homeodomain interacting protein kinase 2
总数:3
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. 2009 至该文献
为研究高密度SNP基础的基因型排列分析检测小儿低级星形细胞瘤7q34重复区发现的新型BRAF融合基因,采用了Abcam公司的抗HIPK2抗体进行免疫组化试验。 更多
HUNK
hormonally up-regulated Neu-associated kinase
ILK
integrin-linked kinase
总数:18
The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model. 2010 至该文献
为了研究磷酸化的Akt对后囊的作用采用了DAKO Corp公司的抗PCNA抗体(1:200稀释)来进行免疫组化实验。 更多
IRAK
interleukin-1 receptor-associated kinase 1
总数:10
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 至该文献
为了研究IRAK-1信号阻断对TLR2和TLR4诱导的人树突状细胞耐受有重要作用,采用Santa Cruz的鼠抗IRAK-1抗体进行蛋白印迹实验。 更多
IRAK M
interleukin-1 receptor-associated kinase 3
总数:1
Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7. 2009 至该文献
为了研究toll-like 受体7在自身免疫性疾病中的作用,采用了Cell Signaling公司的抗 IRAKM抗体产品,进行了免疫印迹实验。
IRAK4
interleukin-1 receptor-associated kinase 4
总数:2
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 至该文献
为了研究IRAK-1信号阻断对TLR2和TLR4诱导的人树突状细胞耐受有重要作用,采用Biomol的兔抗IRAK-4抗体进行蛋白印迹实验。 更多
LATS1
LATS, large tumor suppressor, homolog 1 (Drosophila)
总数:2
Hippo pathway effector Yap is an ovarian cancer oncogene. 至该文献
为了研究hippo通路效应子Yap对卵巢癌发展的影响,采用了Bethyl Laboratories公司的抗Lats-1的抗体进行免疫印迹实验。 更多
LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
总数:2
A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization. 2006 至该文献
LIMK1
LIM domain kinase 1
总数:4
Organized migration of epithelial cells requires control of adhesion and protrusion through Rho kinase effectors. 2007 至该文献
LIMK2
LIM domain kinase 2
总数:2
ROCK1 and LIMK2 interact in spread but not blebbing cancer cells. 2008 至该文献
为了研究ROCK1能够与LIMK2在极性癌细胞中相互作用而不在泡状癌细胞中作用,采用Cell Signalling的抗LIMK2抗体进行蛋白印迹实验。 更多
LKB1
serine/threonine kinase 11
总数:7
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. 2008 至该文献
为研究胰腺Lkb1缺失导致的腺泡极性损失和胞囊肿瘤,采用了Santa Cruz Biotechnology公司的抗Lkb1抗体进行蛋白质印迹和免疫组化试验。 更多
LRRK2
leucine-rich repeat kinase 2
总数:2
CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity. 2009 至该文献
为了确认内源性LRRK2的定位,使用了Santa Cruz Biotechnology公司的兔源抗LRRK2多克隆抗体来染内源LRRK2蛋白。 更多
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
总数:1
Molecular characterization of CD40 signaling intermediates. 2001 至该文献
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
总数:2
NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation. 2005 至该文献
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
MAPKAPK5
mitogen-activated protein kinase-activated protein kinase 5
MARK1
MAP/microtubule affinity-regulating kinase 1
总数:2
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. 2008 至该文献
为研究胰腺Lkb1缺失导致的腺泡极性损失和胞囊肿瘤,采用了Cell Signaling公司的抗磷酸化MARK抗体进行蛋白质印迹和免疫组化试验。 更多
MARK2
MAP/microtubule affinity-regulating kinase 2
总数:2
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. 2008 至该文献
为研究胰腺Lkb1缺失导致的腺泡极性损失和胞囊肿瘤,采用了Novus公司的抗MARK2抗体进行蛋白质印迹和免疫组化试验。 更多
MARK3
MAP/microtubule affinity-regulating kinase 3
总数:1
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. 2008 至该文献
为研究胰腺Lkb1缺失导致的腺泡极性损失和胞囊肿瘤,采用了Upstate公司的抗MARK3抗体进行蛋白质印迹和免疫组化试验。
MARK4
MAP/microtubule affinity-regulating kinase 4
MAST1
microtubule associated serine/threonine kinase 1
MAST2
microtubule associated serine/threonine kinase 2
MAST3
microtubule associated serine/threonine kinase 3
MAST4
microtubule associated serine/threonine kinase family member 4
MASTL
microtubule associated serine/threonine kinase-like
MELK
maternal embryonic leucine zipper kinase
MK2
mitogen-activated protein kinase-activated protein kinase 2
总数:18
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.. 2011 至该文献
为了研究人造血系统细胞给以不同刺激的反应能通过单细胞多因子分选进行分析,采用Cell Signaling Technology的抗MAPKAPK 2 (pT334)抗体以1ug/ml浓度进行细胞多因子分选实验。 更多
MKNK1
MAP kinase interacting serine/threonine kinase 1
总数:1
Interleukins 2 and 15 regulate Ets1 expression via ERK1/2 and MNK1 in human natural killer cells. 2005 至该文献
MOS
v-mos Moloney murine sarcoma viral oncogene homolog
总数:1
Cytostatic factor proteins are present in male meiotic cells and beta-nerve growth factor increases mos levels in rat late spermatocytes. 2009 至该文献
为了证实细胞生长抑制因子蛋白和beta神经生长因子可以提高Mos水平,使用了US Biological公司的抗Mos抗体来进行蛋白印迹分析。
mTOR
mechanistic target of rapamycin (serine/threonine kinase)
总数:32
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H?-ATPase.. 2011 至该文献
为了研究泡状H+-ATPase参与到mTOR通路中mTORC1的转位和激活,采用Cell Signaling的抗mTOR抗体进行蛋白印迹和免疫细胞化学实验。 更多
MYLK4
myosin light chain kinase family, member 4
NDR2
serine/threonine kinase 38 like
NEK1
NIMA (never in mitosis gene a)-related kinase 1
NEK10
NIMA (never in mitosis gene a)- related kinase 10
NEK11
NIMA (never in mitosis gene a)- related kinase 11
NEK2
NIMA (never in mitosis gene a)-related kinase 2
总数:2
Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells. 2004 至该文献
NEK3
NIMA (never in mitosis gene a)-related kinase 3
NEK4
NIMA (never in mitosis gene a)-related kinase 4
NEK5
NIMA (never in mitosis gene a)-related kinase 5
NEK6
NIMA (never in mitosis gene a)-related kinase 6
总数:2
Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis. 2008 至该文献
为了通过大规模基因表达谱分析与基因网络分析研究胃癌中表达过高的基因,采用了Abgent的抗人NEK6抗体以1:500稀释进行免疫印迹实验。 更多
NEK7
NIMA (never in mitosis gene a)-related kinase 7
NEK8
NIMA (never in mitosis gene a)- related kinase 8
NEK9
NIMA (never in mitosis gene a)- related kinase 9
NIM1
serine/threonine-protein kinase NIM1
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
p110
phosphoinositide-3-kinase, catalytic, alpha polypeptide
总数:24
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling.. 2011 至该文献
为了通过磷酸化蛋白组学研究Grb10是胰岛素信号通路的负调控因子,采用BD的抗p110抗体进行蛋白印迹实验。 更多
p70S6K
ribosomal protein S6 kinase, 70kDa, polypeptide 1
总数:59
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H?-ATPase.. 2011 至该文献
为了研究泡状H+-ATPase参与到mTOR通路中mTORC1的转位和激活,采用Cell Signaling的抗S6K1和抗T389磷酸化S6K1抗体进行蛋白印迹实验。 更多
P90核糖体S6激酶 (p90rsk)
ribosomal protein S6 kinase, 90kDa, polypeptide 1
总数:21
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs.. 2010 至该文献
为了研究4E-BPs对mTORC1信号通路的精确调控,使用了Cell Signaling Technology公司的抗RSK1和抗磷酸化RSK1抗体来进行免疫印迹分析。 更多
PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
总数:28
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 至该文献
为了将Pak4鉴定为位于Met受体下游的一种新的与Gab1相互作用的蛋白并研究其功能,采用了Epitomics公司的兔单克隆抗Pak1抗体,进行了蛋白质印迹实验。 更多
Pak2
p21 protein (Cdc42/Rac)-activated kinase 2
总数:6
Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death. 2009 至该文献
为了研究PAK-2在调控抗癌药物诱发细胞凋亡中的作用,采用了Santa Cruz Biotechnology 公司的抗PAK-2抗体产品,进行了免疫印迹实验 更多
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
总数:1
Elevated p21-activated kinase 2 activity results in anchorage-independent growth and resistance to anticancer drug-induced cell death. 2009 至该文献
为了研究PAK-2在调控抗癌药物诱发细胞凋亡中的作用,采用了Santa Cruz Biotechnology 公司的抗PAK-3抗体产品,进行了免疫印迹实验
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
总数:3
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 至该文献
为了将Pak4鉴定为位于Met受体下游的一种新的与Gab1相互作用的蛋白并研究其功能,采用了Cell Signaling Technology公司的多克隆抗磷酸化的Pak4抗体,进行了蛋白质印迹实验。 更多
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
总数:2
Mechanism of p21-activated kinase 6-mediated inhibition of androgen receptor signaling. 2004 至该文献
PAK7
p21 protein (Cdc42/Rac)-activated kinase 7
总数:1
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties. 2006 至该文献
PASK
PAS domain containing serine/threonine kinase
PDPK1
3-phosphoinositide dependent protein kinase-1
总数:8
Estrogen receptor (ER)alpha and ER beta are both expressed in human ejaculated spermatozoa: evidence of their direct interaction with phosphatidylinositol-3-OH kinase/Akt pathway. 2004 至该文献
PERK
eukaryotic translation initiation factor 2-alpha kinase 3
总数:13
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 至该文献
为了说明Skp2参与非p19Arf-p53途径的细胞衰老,使用了Cell Signaling公司的Perk磷酸化抗体(Thr980)来进行免疫印记实验。 更多
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
总数:10
MMP-28 as a regulator of myelination. 2008 至该文献
细胞信号转导用磷酸化PI3K抗体(编号:4228P) 可用于免疫印迹实验,来研究基质金属蛋白酶MMP-28在髓鞘形成过程中的作用。 更多
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
总数:1
Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. 2008 至该文献
使用Abgent公司的兔抗hVps15抗体进行免疫印迹实验来鉴别哪一个Aas信号到hVps34是激活mTOR复合体1信号通路的途径和机制。
PIM1
pim-1 oncogene
总数:6
KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA. 2009 至该文献
为了研究卡波西肉瘤疱疹病毒(KSHV)的抑制需要Pim-1和Pim2激酶作用,使用Santa Cruz anti-Pim-1抗体进行western blot和免疫沉淀实验。 更多
PIM2
pim-2 oncogene
总数:3
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation.. 2011 至该文献
为了研究切割的NIK 导致非经典的NF- kB 活性 ,采用了Santa Cruz Biotechnology的抗IPim-2抗体进行免疫印迹实验。 更多
PIM3
pim-3 oncogene
总数:4
Cooperation between molecular targets of costimulation in promoting T cell persistence and tumor regression. 2009 至该文献
为了研究不同实质肿瘤(293,Hela and PCI-43)在正常和缺氧情况下Pim-3的表达水平,采用了ABGENT的抗Pim-1抗体进行免疫印迹实验。 更多
PINK1
PTEN induced putative kinase 1
总数:3
Glutamine Deamidation and Dysfunction of Ubiquitin/NEDD8 Induced by a Bacterial Effector Family.. 2010 至该文献
为了研究类鼻疽杆菌的CHBP蛋白作为真核细胞的泛素化途径的强抑制剂的功能,使用了Novus Biologicals公司的抗PINK1抗体来进行免疫印迹分析。 更多
PKMYT1
protein kinase, membrane associated tyrosine/threonine 1
PKR
eukaryotic translation initiation factor 2-alpha kinase 2
总数:30
The adenovirus E1B 55-kilodalton and E4 open reading frame 6 proteins limit phosphorylation of eIF2alpha during the late phase of infection. 2009 至该文献
为了研究E1B-55K/E4orf6复合物同eIF2α的关系,采用了Cell Signaling Technology公司的兔单克隆PKR抗体,进行了蛋白印记实验。 更多
PRKAA1
protein kinase, AMP-activated, alpha 1 catalytic subunit
总数:15
Signaling Kinase AMPK Activates Stress-Promoted Transcription via Histone H2B Phosphorylation.. 2010 至该文献
为了研究AMP激活的蛋白激酶调节细胞对代谢压力的反应的机制,使用了Cell Signaling Technologies公司的抗PRKAA1抗体来进行免疫印迹分析。 更多
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
总数:4
Signaling Kinase AMPK Activates Stress-Promoted Transcription via Histone H2B Phosphorylation.. 2010 至该文献
为了研究AMP激活的蛋白激酶调节细胞对代谢压力的反应的机制,使用了R&D technologies公司的抗PRKAA2抗体来进行免疫印迹分析和染色质免疫沉淀实验。 更多
PRKX
protein kinase, X-linked
总数:1
Profiles of PrKX expression in developmental mouse embryo and human tissues. 2005 至该文献
PRPF4B
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
Raf-1
v-raf-1 murine leukemia viral oncogene homolog 1
总数:45
Constitutive activation of Raf-1 induces glioma formation in mice. 2008 至该文献
为了研究Raf-1对神经胶质瘤形成的作用,采用了Santa Cruz Biotechnology的抗Raf-1抗体进行免疫印迹实验。 更多
RIP
receptor (TNFRSF)-interacting serine-threonine kinase 1
总数:9
Repression of NF-kappaB and activation of AP-1 enhance apoptosis in prostate cancer cells. 2009 至该文献
为研究NF-κB的抑制和AP-1的激活对前列腺癌细胞凋亡的影响,将Santa Cruz提供的抗RIP抗体用于蛋白免疫印迹实验中。 更多
RIP3
receptor-interacting serine-threonine kinase 3
总数:1
Hyaluronan-mediated CD44 interaction with RhoGEF and Rho kinase promotes Grb2-associated binder-1 phosphorylation and phosphatidylinositol 3-kinase signaling leading to cytokine (macrophage-colony stimulating factor) production and breast tumor progressio. 2003 至该文献
RIPK2
receptor-interacting serine-threonine kinase 2
总数:2
Molecular characterization of CD40 signaling intermediates. 2001 至该文献
RIPK4
receptor-interacting serine-threonine kinase 4
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
总数:8
Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. 2009 至该文献
为了研究ROCK1和ROCK2在调节角化细胞黏附和终末分化中的不同作用,采用了Santa Cruz的抗ROCK1抗体进行免疫印迹实验 更多
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
总数:5
RhoE Is required for keratinocyte differentiation and stratification. 2009 至该文献
为研究RhoE在角质化细胞的分化和层化过程中所发挥的角色,将Santa Cruz提供的兔多克隆抗ROCKII抗体(H-85)用于蛋白免疫印迹实验中。 更多
RPK118
ribosomal protein S6 kinase, 52kDa, polypeptide 1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
总数:9
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. 2009 至该文献
为了研究在人的近曲小管细胞中GRK4对于D3受体信号传导的重要作用,使用了Cell Signaling公司的抗磷酸化p90RSK抗体进行免疫印迹实验。 更多
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
总数:9
Mitogen-activated protein kinase-activated kinase RSK2 plays a role in innate immune responses to influenza virus infection. 2009 至该文献
为了研究RSK2在细胞抗病毒应答反应中所起的作用,使用了Santa Cruz公司的抗RSK2抗体来进行蛋白印迹分析。 更多
RPS6KA4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
总数:1
mTOR cascade activation distinguishes tubers from focal cortical dysplasia. 2004 至该文献
在免疫组化实验中使用了Cell Signalling Technology公司的磷酸化S6(Ser235/236)抗体(1:200稀释)用于证明mTOR级联激活可以区分瘤和局部的皮质发育异常。
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
总数:3
Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation. 2009 至该文献
Santa Cruz Biotechnology MSK1抗体用于免疫印记来研究MSK1在调控NF-κB活性和发炎性疾病中的作用 更多
RPS6KB2
ribosomal protein S6 kinase, 70kDa, polypeptide 2
总数:2
Hypoxia-induced energy stress inhibits the mTOR pathway by activating an AMPK/REDD1 signaling axis in head and neck squamous cell carcinoma. 2008 至该文献
为了研究低氧引起的能量应激在调控头颈扁平细胞瘤中mTOR信号通路中的作用,采用了 Cell Signaling Technology公司的兔多克隆抗磷酸化p70 S6(Thr389)抗体产品,进行了免疫印迹实验 更多
RSK4
ribosomal protein S6 kinase, 90kDa, polypeptide 6
SBK1
SH3-binding domain kinase 1
SBK2
SH3-binding domain kinase family, member 2
SGK1
serum/glucocorticoid regulated kinase 1
总数:6
Hsp90 regulates the phosphorylation and activity of serum- and glucocorticoid-regulated kinase-1. 2008 至该文献
为了研究热休克蛋白如何调节糖皮质激素调节激酶- 1基于磷酸肌醇3激酶的磷酸化,采用了圣克鲁斯公司的phospho-Ser-422抗体,进行蛋白质印记实验。 更多
SGK110
putative uncharacterized serine/threonine-protein kinase SgK110-like
SGK3
serum/glucocorticoid regulated kinase family, member 3
SGK494
uncharacterized serine/threonine-protein kinase SgK494
SIK1
salt-inducible kinase 1
总数:1
SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis. 2009 至该文献
为了研究盐诱导激酶1同失巢凋亡和转移的关系,采用了Abgent公司的SIK1抗体,进行蛋白印记了实验。
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
SNARK
NUAK family, SNF1-like kinase, 2
SPAK
serine threonine kinase 39
总数:2
PKCdelta acts upstream of SPAK in the activation of NKCC1 by hyperosmotic stress in human airway epithelial cells. 2008 至该文献
为了研究SPAK在PKCδ介导的NKCC1激活中的作用,采用了Abgent公司的兔抗SPAK多克隆抗体进行免疫印迹实验。 更多
SRPK1
SRSF protein kinase 1
总数:3
Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones. 2009 至该文献
为了研究SRPK1在调控SR蛋白磷酸化修饰中的作用,采用了BD Transduction Laboratories公司的SRPK1抗体产品,进行了免疫印迹实验 更多
SRPK2
SRSF protein kinase 2
总数:2
Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones. 2009 至该文献
为了研究SRPK1在调控SR蛋白磷酸化修饰中的作用,采用了BD Transduction Laboratories公司的SRPK2抗体产品,进行了免疫印迹实验 更多
STK24
serine/threonine kinase 24
总数:1
Targeted disruption of the gene for the PAK5 kinase in mice. 2003 至该文献
为了研究PAK5激酶在小鼠中的靶向分裂,采用了Upstate Biotechnology公司的Ste20抗体进行蛋白质印迹分析。
STK3
serine/threonine kinase 3
总数:1
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. 2010 至该文献
为了研究吐根信号对哺乳动物器官大小的调控作用,使用了Cell Signaling公司的Mst2抗体,进行了免疫印迹实验。
STK4
serine/threonine kinase 4
总数:1
Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis. 2006 至该文献
Cell Signaling公司的兔源性Mst1多克隆抗体可用于免疫印迹实验,来检测人 293T and U2OS细胞中Mst1的表达。
TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
总数:6
Identification of novel functional TBP-binding sites and general factor repertoires. 2007 至该文献
TAOK1
TAO kinase 1
总数:2
TAO kinases mediate activation of p38 in response to DNA damage. 2007 至该文献
为研究TAO激酶在DNA损伤应答中的作用,采用BD公司的羊源性TAO1抗体用于免疫印迹实验。 更多
TAOK3
TAO kinase 3
总数:1
TAO kinases mediate activation of p38 in response to DNA damage. 2007 至该文献
为研究TAO激酶在DNA损伤应答中的作用,采用Serotec公司的羊源性TAO3抗体用于免疫印迹实验。
TBK1
TANK-binding kinase 1
总数:6
Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth.. 2011 至该文献
为了研究沙门氏菌的生长被自噬受体optineurin的磷酸化限制,采用Epitomics的抗磷酸化TBK1pS172抗体进行蛋白印迹实验。 更多
titin
总数:2
Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy. 2007 至该文献
Siegfried Labeit(tsklinikum Mannheim大学)的抗肌联蛋白N2B 抗体(1:200)被用于免疫组织化学实验,来研究肌联蛋白N2B结构域在心脏收缩和舒张中的作用。 更多
TNK2
tyrosine kinase, non-receptor, 2
总数:5
Human SIRT6 promotes DNA end resection through CtIP deacetylation.. 2010 至该文献
为了阐明SIRT6促进DNADNA末端切除的机制,使用了Biomol公司的小鼠抗AcK-2抗体来进行免疫印迹分析。 更多
TRIO
triple functional domain (PTPRF interacting)
TRPM6
transient receptor potential cation channel, subfamily M, member 6
TRPM7
transient receptor potential cation channel, subfamily M, member 7
总数:1
Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation. 2007 至该文献
为了研究TRPM7样蛋白在人头部和颈部肿瘤细胞增殖所起作用,使用Abgent公司的抗TRPM7抗体进行免疫组织化学实验。
TSSK5
testis-specific serine kinase 4
TTBK1
tau tubulin kinase 1
总数:1
Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation. 2006 至该文献
Alpha Diagnostic的兔源多克隆抗血清(多克隆抗体,7589,抗一段人工合成的TTBK1308 321肽段,序列为FDWEKAGTDALLST)被用于蛋白质印迹实验来检测小鼠皮质、COS-7细胞和人HEK293细胞中的TTBK1水平,并用于免疫细胞化学实验来检测COS-7细胞中的TTBK1水平。
UHMK1
U2AF homology motif (UHM) kinase 1
总数:2
KIS protects against adverse vascular remodeling by opposing stathmin-mediated VSMC migration in mice. 2008 至该文献
为研究KIS介导的stathmin依赖性VSMC迁移反向,采用了Abgent公司的兔源抗KIS抗体进行蛋白质印迹试验。 更多
ULK1
unc-51-like kinase 1 (C. elegans)
总数:2
Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism. 2009 至该文献
为了说明激酶未激活的ULK蛋白可以通过一种依赖于Atg13的机制来抑制自我吞噬,使用了Santa Cruz Biotechnology公司的抗ULK1多克隆抗体来进行免疫沉淀实验。 更多
ULK2
unc-51-like kinase 2 (C. elegans)
总数:1
Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons. 2007 至该文献
ULK3
unc-51-like kinase 3 (C. elegans)
ULK4
unc-51-like kinase 4 (C. elegans)
WNK2
WNK lysine deficient protein kinase 2
WNK3
WNK lysine deficient protein kinase 3
WNK4
WNK lysine deficient protein kinase 4
总数:2
WNK kinases regulate thiazide-sensitive Na-Cl cotransport. 2003 至该文献
YSK4
YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
ZIP
death-associated protein kinase 3