阿片类物质信号
基因
试剂
文献样例
产品评述样例
ACTH
proopiomelanocortin
总数:8
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 至该文献
ADCY1
adenylate cyclase 1
总数:2
Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase. 2005 至该文献
ADCY2
adenylate cyclase 2
总数:2
Stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. 2007 至该文献
为了研究腺苷酸环化酶2的稳定表达能导致CHODUKX细胞系中人5-HT6受体功能修复,采用了Santa Cruz Biotechnology公司的AC2抗体进行蛋白质印迹分析 更多
ADCY3
adenylate cyclase 3
总数:3
Plasma membrane calcium pumps in mouse olfactory sensory neurons. 2006 至该文献
为了研究不同亚型的细胞膜钙泵在不同的分布区域有着各自的特性作用,以及细胞膜钙泵在小鼠嗅感觉神经元中的作用机理,采用了Santa Cruz公司的三腺苷酸环化酶抗体,进行细胞免疫荧光实验。 更多
ADCY5
adenylate cyclase 5
总数:3
Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB. 2007 至该文献
CAMK4
calcium/calmodulin dependent protein kinase IV
总数:3
Evidence of the presence of calcium/calmodulin-dependent protein kinase IV in human sperm and its involvement in motility regulation. 2005 至该文献
Cdk5
cyclin dependent kinase 5
总数:8
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. 2009 至该文献
为了揭示在CXCL12诱发的T淋巴细胞迁移过程中CRMP2功能的分子机制,采用了Santa Cruz Biotechnology公司的抗Cdk5(SC-173)抗体,抗Cdk5第15位Tyr磷酸化抗体(SC-12928),抗Cdk5第159位Ser磷酸化抗体(SC-12919)进行免疫印迹实验。 更多
CREB
cAMP responsive element binding protein 1
总数:58
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 至该文献
为了说明流感病毒感染期间IL-32表达水平的提高抑制病毒的复制,使用了Santa Cruz Biotechnology公司的anti-CREB1抗体来进行染色质免疫共沉淀实验。 更多
ERK2
mitogen-activated protein kinase 1
总数:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 至该文献
为了研究在气喘患者中由TGFbeta和IL-10抑制造成的对T细胞的抗性的信号传导机制,采用了Santa Cruze Biotechnology的抗ERK1/2抗体和抗磷酸化ERK1/2抗体进行了免疫印迹检测,免疫组化实验和流式细胞检测。 更多
GNAI2
G protein subunit alpha i2
总数:5
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 至该文献
为了研究β2-肾上腺素受体激动剂fenoterol的立体化学在决定受体G蛋白选择性和下游信号通路中的功能,使用了Abcam公司的兔抗GNAI2抗体来进行免疫沉淀实验。 更多
GNAI3
G protein subunit alpha i3
总数:6
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 至该文献
为了研究β2-肾上腺素受体激动剂fenoterol的立体化学在决定受体G蛋白选择性和下游信号通路中的功能,使用了Santa Cruz Biotechnology公司的兔抗GNAI3抗体来进行免疫沉淀实验。 更多
GNAT3
G protein subunit alpha transducin 3
总数:1
Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon. 2006 至该文献
GNB5
G protein subunit beta 5
总数:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 至该文献
GRK2
G protein-coupled receptor kinase 2
总数:9
Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2. 2008 至该文献
为了研究在冠状动脉旁路移植中,GRK2对心肌肾上腺素受体信号解偶联的作用,采用了Santa Cruz Biotechnolog的GRK2多抗,进行心肌衰弱水平的免疫检测 更多
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
总数:5
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 至该文献
为了研究在Purkinje神经元细胞膜钙ATP酶2缺失的小脑的分子变化,采用了Calbiochem公司的IP3R1抗体进行蛋白质印迹杂家和免疫组织化学分析。 更多
ITPR2
inositol 1,4,5-trisphosphate receptor type 2
总数:2
Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression. 2005 至该文献
PDE1B
phosphodiesterase 1B
总数:2
Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase. 2006 至该文献
PDE4A
phosphodiesterase 4A
总数:3
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 至该文献
PDE4C
phosphodiesterase 4C
总数:1
Short-term or long-term treatments with a phosphodiesterase-4 (PDE4) inhibitor result in opposing agonist-induced Ca(2+) responses in endothelial cells. 2008 至该文献
PDE4D
phosphodiesterase 4D
总数:1
Expression of the cAMP-phosphodiesterase PDE4D isoforms and age-related changes in follicle-stimulating hormone-stimulated PDE4 activities in immature rat sertoli cells. 2007 至该文献
磷脂酶C乙4 (phospholipase C beta 4)
总数:2
A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients. 2005 至该文献
PKC甲 (PKC alpha)
protein kinase C alpha
总数:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 至该文献
为了研究TMX3基因在眼发育中的功能,采用了Santa Cruz Biotechnology公司的兔抗PKCAα抗体,进行了蛋白质印迹实验. 更多
PKC delta
protein kinase C delta
总数:35
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. 2009 至该文献
为了研究在肠部PKCα抑制肿瘤的机制,采用了Santa Cruz Biotechnology公司的抗PKCδ抗体,进行了蛋白质印迹实验。 更多
PLA2G4A
phospholipase A2 group IVA
总数:8
Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport.. 2009 至该文献
为了研究cPLA2a在高尔基复合体转运中池内管状连续物的形成中的作用,采用了Santa Cruz Biotechnology的抗cPLA2a抗体进行免疫印迹实验免疫细胞化学实验 更多
PLCB2
phospholipase C beta 2
总数:3
Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx. 2005 至该文献
PP1
protein phosphatase 1 catalytic subunit alpha
总数:19
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. 2008 至该文献
为了研究参与调控SRC-3/AIB1辅激活物的功能与降解的基本磷酸酶和决定SRC-3/AIB1降解的磷酸化降解决定子,采用了Santa Cruz的抗PP1alpha抗体进行免疫印迹实验。 更多
PP2AC
protein phosphatase 2 catalytic subunit alpha
总数:20
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 至该文献
PPP1R1B
protein phosphatase 1 regulatory inhibitor subunit 1B
总数:3
Brain-specific regulator of G-protein signaling 9-2 selectively interacts with alpha-actinin-2 to regulate calcium-dependent inactivation of NMDA receptors. 2006 至该文献
PPP2R1A
protein phosphatase 2 scaffold subunit Aalpha
总数:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 至该文献
PPP2R1B
protein phosphatase 2 scaffold subunit Abeta
总数:2
SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process. 2007 至该文献
为了研究sk1的功能,采用了Sigma-Aldrich公司的单克隆抗PP2A抗体,进行了蛋白印记实验。 更多
PPP3CA
protein phosphatase 3 catalytic subunit alpha
总数:4
Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis. 2009 至该文献
为了推断钙调磷酸酶活性和白血病细胞凋亡能够通过糖皮质激素介导上调的RCAN1-1来调节,使用了Sigma-Aldrich公司的抗体calcineurin A来进行免疫印迹分析。 更多
PPP3CB
protein phosphatase 3 catalytic subunit beta
总数:2
Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models. 2005 至该文献
Chemicon的兔抗磷酸酶抗体被用于免疫组化实验,来研究触发星形胶质细胞活性的机制。 更多
PPP3R1
protein phosphatase 3 regulatory subunit B, alpha
总数:3
Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. 2006 至该文献
为了研究ASK1和控制心肌病死亡和生长的钙调磷蛋白磷酸酶-NFAT之间的直接相互作用和可逆调节,采用了Sigma公司的CnB1抗体进行了蛋白质印迹分析 更多
PRKACA
protein kinase cAMP-activated catalytic subunit alpha
总数:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 至该文献
为了说明在人NT2细胞中血管活性肠肽可以促进HCMV MIE的表达,使用了Santa Cruz Biotechnology公司的兔多克隆抗PKA催化亚基抗体来进行蛋白印迹实验。 更多
PRKACG
protein kinase cAMP-activated catalytic subunit gamma
总数:4
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. 2006 至该文献
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
总数:9
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 至该文献
在免疫组化实验中使用了EMD Biosciences公司的针对RIalpha的单克隆抗体用于检测人肾上腺样本中PKA的亚基Calpha。 更多
PRKAR2A
protein kinase cAMP-dependent type II regulatory subunit alpha
总数:9
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 至该文献
为了研究在β1AR刺激的肌细胞收缩过程中,PP2A限制PKA对受磷蛋白和Tnl磷酸化的作用,采用了Santa Cruz Biotechnology的抗PKA RII抗体,进行蛋白质印迹实验 更多
PRKAR2B
protein kinase cAMP-dependent type II regulatory subunit beta
总数:3
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. 2006 至该文献
在免疫组化实验中使用了EMD Biosciences公司的针对RIIbeta的单克隆抗体用于检测人肾上腺样本中PKA的亚基Calpha。 更多
PRKCG
protein kinase C gamma
总数:12
The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. 2007 至该文献
prodynorphin
总数:3
PROPELLER MRI visualizes detailed pathology of hippocampal sclerosis. 2008 至该文献
使用Serotec的多克隆抗强啡肽抗体进行免疫组织化学实验来比较海马的PROPELLER图像处理与人海马样本切片的常规序列之间的区别。 更多