PCP/CE通路
基因
试剂
文献样例
产品评述样例
α-衔接蛋白 (alpha-adaptin)
adaptor related protein complex 2 subunit alpha 1
总数:17
FCHo proteins are nucleators of clathrin-mediated endocytosis. 2010 至该文献
为了研究FCHo1和FCHo2蛋白在细胞膜上的clathrin介导的内吞作用中的功能，使用了Transduction Laboratories公司的小鼠抗AP2A1单克隆抗体来进行免疫印迹分析。 更多
AP2A2
adaptor related protein complex 2 subunit alpha 2
总数:5
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 至该文献
运用Sigma公司的抗alpha-Adaptin抗体，进行免疫印迹实验以揭示神经细胞和非神经细胞中赫曼斯基-普德拉克综合征蛋白复合体与磷脂酰肌醇4-激酶二型α的相互作用。 更多
AP2B1
adaptor related protein complex 2 subunit beta 1
总数:5
Death-receptor activation halts clathrin-dependent endocytosis. 2006 至该文献
为了研究死亡受体引发基于网格蛋白的内吞作用以及刺激诱导半胱天冬酶介导的主要网格蛋白组分的剪切，阻止细胞摄取经典的货物转运蛋白―铁传递蛋白，采用了BD Transduction Laboratories公司接头蛋白alpha抗体，进行蛋白质印记实验。 更多
AP2M1
adaptor related protein complex 2 subunit mu 1
总数:2
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. 2006 至该文献
AP2S1
adaptor related protein complex 2 subunit sigma 1
ARRB2
arrestin beta 2
总数:3
Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation. 2006 至该文献
网格蛋白重链 (Clathrin Heavy Chain)
clathrin heavy chain
总数:28
Stapled Golgi cisternae remain in place as cargo passes through the stack. 2013 至该文献
为了研究高尔基体介导的蛋白转运机制，Millipore的兔抗网格蛋白抗体被用于进行免疫电镜实验。 更多
CLTA
clathrin light chain A
总数:5
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 至该文献
为了研究株系变化对羊痒痒症的PrP蛋白运输通路的影响，使用了Sigma-Aldrich公司的抗clathrin轻链单克隆抗体来进行免疫组化实验。 更多
CLTB
clathrin light chain B
DAAM1
dishevelled associated activator of morphogenesis 1
DVL1
dishevelled segment polarity protein 1
总数:2
Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. 2009 至该文献
使用Santa Cruz生物公司的抗Dvl抗体进行免疫组织化学实验来研究骨形态发生蛋白2在引起肺血管发生中的作用和机制。 更多
DVL2
dishevelled segment polarity protein 2
总数:4
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. 2007 至该文献
Santa Cruz Biotechnology的Dvl2抗体被用于蛋白质印迹实验，来证明在神经细胞中CK1是Wnt-5a-Dvl通路的附加成份。 更多
DVL3
dishevelled segment polarity protein 3
总数:3
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. 2007 至该文献
Santa Cruz Biotechnology的Dvl3抗体被用于蛋白质印迹实验，来证明在神经细胞中CK1是Wnt-5a-Dvl通路的附加成份。 更多
frizzled 3
frizzled class receptor 3
FZD1
frizzled class receptor 1
FZD2
frizzled class receptor 2
FZD5
frizzled class receptor 5
FZD6
frizzled class receptor 6
FZD7
frizzled class receptor 7
gankyrin
proteasome 26S subunit, non-ATPase 10
p44S10
proteasome 26S subunit, non-ATPase 6
PA200
proteasome activator subunit 4
总数:1
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体调节蛋白PA200抗体,进行了蛋白质印迹实验.
PFN1
profilin 1
总数:4
Self-assembly of filopodia-like structures on supported lipid bilayers. 2010 至该文献
为了研究丝状伪足样结构是如何自组装的，使用了Axxora公司的抗profilin抗体来进行免疫荧光实验。 更多
PKC甲 (PKC alpha)
protein kinase C alpha
总数:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 至该文献
为了研究TMX3基因在眼发育中的功能,采用了Santa Cruz Biotechnology公司的兔抗PKCAα抗体,进行了蛋白质印迹实验. 更多
PKC乙 (PKC beta)
protein kinase C beta
总数:27
Protein kinase C in porcine retinal arteries and neuroretina following retinal ischemia-reperfusion. 2009 至该文献
为了研究PKC在调控视猪网膜缺血再灌注过程中的作用，采用了Santa Cruz Biotechnology公司的鼠单克隆抗beta-actin抗体产品(1:5000)，进行了免疫印迹实验 更多
PRICKLE1
prickle planar cell polarity protein 1
PRKCG
protein kinase C gamma
总数:12
The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. 2007 至该文献
PSMA1
proteasome 20S subunit alpha 1
总数:9
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 至该文献
PSMA3
proteasome 20S subunit alpha 3
总数:3
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 至该文献
为了研究内着丝粒是如何建立的和CPC复合物是如何靶向到此位点的机制，使用了Santa Cruz Biotechnology公司的抗Psc3抗体来进行染色质免疫沉淀实验。 更多
PSMA4
proteasome 20S subunit alpha 4
总数:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献
为了研究免疫蛋白酶体在多发性硬化发病机制的作用，采用Affinity-Biomol International小鼠抗人的20S proteasome subunit alpha4单克隆抗体进行免疫组织化学试验。 更多
PSMA7
proteasome 20S subunit alpha 7
总数:4
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 至该文献
为了在内质网相关蛋白的降解途径（ERAD）中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能，使用了Enzo Life Sciences公司的抗体alpha7来进行免疫印迹分析。 更多
PSMA8
proteasome 20S subunit alpha 8
PSMB1
proteasome 20S subunit beta 1
总数:2
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体亚基β1抗体,进行了蛋白质印迹实验. 更多
PSMB10
proteasome 20S subunit beta 10
PSMB11
proteasome subunit beta 11
PSMB4
proteasome 20S subunit beta 4
PSMB5
proteasome 20S subunit beta 5
总数:1
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体亚基β5抗体,进行了蛋白质印迹实验.
PSMB6
proteasome 20S subunit beta 6
PSMB7
proteasome 20S subunit beta 7
PSMB8
proteasome 20S subunit beta 8
总数:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献
为了研究免疫蛋白酶体在多发性硬化发病机制的作用，采用Affinity-Biomol International抗LMP7抗体进行免疫组织化学试验。 更多
PSMB9
proteasome 20S subunit beta 9
总数:2
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献
为了研究免疫蛋白酶体在多发性硬化发病机制的作用，采用Affinity-Biomol International抗LMP2抗体进行免疫组织化学试验。 更多
PSMC1
proteasome 26S subunit, ATPase 1
PSMC4
proteasome 26S subunit, ATPase 4
总数:8
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 至该文献
为了研究在帕金森疾病模型中雷怕霉素对神经元的保护作用，采用了Cell Signaling Technology的抗phospho-Ser235/236-S6抗体进行免疫细胞化学试验。 更多
PSMC6
proteasome 26S subunit, ATPase 6
总数:1
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 至该文献
PSMD1
proteasome 26S subunit, non-ATPase 1
PSMD11
proteasome 26S subunit, non-ATPase 11
PSMD12
proteasome 26S subunit, non-ATPase 12
PSMD13
proteasome 26S subunit, non-ATPase 13
PSMD14
proteasome 26S subunit, non-ATPase 14
PSMD2
proteasome 26S subunit, non-ATPase 2
总数:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 至该文献
为了说明hHR23A介导的Vpr与蛋白酶体的互作在病毒复制过程中有重要作用，使用了Calbiochem公司的19S蛋白酶体S2亚基的兔多抗来进行免疫印记实验。
PSMD4
proteasome 26S subunit, non-ATPase 4
总数:3
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 至该文献
为了说明hHR23A介导的Vpr与蛋白酶体的互作在病毒复制过程中有重要作用，使用了Calbiochem公司的19S蛋白酶体S5a亚基的兔多抗来进行免疫印记实验。 更多
PSMD5
proteasome 26S subunit, non-ATPase 5
PSMD7
proteasome 26S subunit, non-ATPase 7
PSMD8
proteasome 26S subunit, non-ATPase 8
PSMD9
proteasome 26S subunit, non-ATPase 9
总数:13
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 至该文献
为了研究在管腔乳腺癌中雌激素敏感性以及抗雌激素抗性的获得，采用了Santa Cruz 的抗p27抗体进行了western blot实验。 更多
PSME1
proteasome activator subunit 1
总数:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献
为了研究免疫蛋白酶体在多发性硬化中的作用，采用Affinity-Biomol International兔抗PA28alpha多克隆抗体进行免疫组织化学试验。 更多
PSME2
proteasome activator subunit 2
总数:1
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 至该文献
为了确认长期酒精喂养对蛋白酶体相互作用蛋白表达的影响，采用了BIOMOL公司的抗PA28β抗体进行免疫印迹法实验。
PSME3
proteasome activator subunit 3
PSMF1
proteasome inhibitor subunit 1
Ras相关C3肉毒杆菌毒素底物1 (Rac1)
Rac family small GTPase 1
总数:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 至该文献
为研究RhoGDI2通过Rho GTPases抑制代谢的作用，采用了Millipore公司的抗Rac1单克隆抗体(1:1,000)进行免疫印迹试验。 更多
RAC2
Rac family small GTPase 2
总数:3
In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression. 2009 至该文献
为了研究ROR2在淋巴瘤侵润性的作用，采用Proteintech公司的Rac2抗体，进行了蛋白印记实验。 更多
RAC3
Rac family small GTPase 3
RhoA
ras homolog family member A
总数:49
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 至该文献
为了研究沉默RhoA和RhoC的表达对人类结直肠癌体内生长的影响，采用Santa Cruz公司的抗RhoA抗体进行了免疫组织化学实验。 更多
ROR1
receptor tyrosine kinase like orphan receptor 1
ROR2
receptor tyrosine kinase like orphan receptor 2
总数:2
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 至该文献
为了研究ROR2调节转移性黑色素瘤的Wnt5A，采用Cell Signaling公司的ROR2抗体，进行了细胞免疫荧光实验。 更多
RPS27A
ribosomal protein S27a
总数:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 至该文献
为了在内质网相关蛋白的降解途径（ERAD）中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能，使用了Santa Cruz Biotechnology公司的抗体ubiquitin来进行免疫印迹分析。 更多
RYK
receptor like tyrosine kinase
S3
proteasome 26S subunit, non-ATPase 3
SCRIB
scribble planar cell polarity protein
总数:2
Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development. 2009 至该文献
为了阐述Hippo信号通路是斑马鱼正常的前肾发育所必须的，并且Scribble参与该通路，采用了Santa Cruz公司的兔多克隆和山羊多克隆抗Scribble抗血清(1:500)，进行了免疫沉淀实验。 更多
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
总数:3
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 至该文献
为了研究Smurf2在促进乳腺癌转移中的功能，使用了Santa Cruz Biotechnology公司的抗Smurf1抗体来进行免疫印迹分析和免疫组化实验。 更多
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
总数:3
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 至该文献
为了研究Smurf2在促进乳腺癌转移中的功能，使用了Santa Cruz Biotechnology公司的抗Smurf2抗体来进行免疫印迹分析和免疫组化实验。 更多
UBC
ubiquitin C
总数:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 至该文献
为了研究突触的可塑性，采用了Enzo Life Sciences的抗Ubiquitin的抗体进行了免疫印迹实验。 更多
泛肽 (ubiquitin)
ubiquitin B
总数:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 至该文献
为了阐明BCL6和HB-EGF-CTF相互作用，并且这种相互作用可能会引起细胞周期蛋白D2在人胃癌细胞中表达，采用了Cell Signaling Technology公司的小鼠抗泛素单克隆抗体，进行了蛋白质印迹实验。 更多
VANGL2
VANGL planar cell polarity protein 2
WNT1
Wnt family member 1
总数:4
WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. 2009 至该文献
为了研究WISP1在调控ATTⅡ细胞超常增生及可塑性中的作用，使用了Abcam公司的抗WNT1抗体，进行了免疫印迹和组织化学实验。 更多
WNT11
Wnt family member 11
WNT4
Wnt family member 4
总数:2
Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen. 2008 至该文献
为了证明Erα与β-catenin/Lef-1/Tcf-3信号的整合，是子宫中雌激素依赖的内源基因调控的必要过程，采用了Santa Cruz Biotechnology的经亲和纯化的Wnt-4抗体，进行蛋白质印迹实验 更多
WNT5A
Wnt family member 5A
总数:4
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 至该文献
为了研究Wnt5A对ROR2的影响，采用BD公司的Wnt5A抗体，进行了蛋白印记实验。 更多
WNT5B
Wnt family member 5B