Phase 1 - Functionalization of compounds
基因
试剂
文献样例
产品评述样例
ACSS1
acyl-CoA synthetase short chain family member 1
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ALDH1A1
aldehyde dehydrogenase 1 family member A1
总数:2
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 至该文献
为了研究c-Src激酶是否会促使非典型小叶增生或小叶原位癌转变为浸润性小叶癌,使用了Epitomics公司的抗Aldh1抗体(1:150)进行免疫荧光实验。 更多
芳香酶 (aromatase)
cytochrome P450 family 19 subfamily A member 1
总数:4
GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome. 2008 至该文献
为了研究GPRC6A的生理功能,采用了Santa Cruz Biotechnology公司的羊抗CYP19(1:200)多克隆抗体进行免疫组化实验。 更多
Cyp1A1
cytochrome P450 family 1 subfamily A member 1
总数:15
Potential therapeutic significance of increased expression of aryl hydrocarbon receptor in human gastric cancer. 2009 至该文献
为确定芳香烃受体在胃癌发生过程中的功能性意义,并探讨其在胃癌治疗中可能发挥的作用,将Chemicon International提供的抗CYP 1A1抗体(AB1258)用于蛋白免疫印迹实验中。 更多
CYP1A2
cytochrome P450 family 1 subfamily A member 2
总数:2
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 至该文献
CYP1B1
cytochrome P450 family 1 subfamily B member 1
总数:8
Preferential induction of cytochrome P450 1A1 over cytochrome P450 1B1 in human breast epithelial cells following exposure to quercetin. 2008 至该文献
亲和纯化的羊源性抗Cyp1B多克隆抗体(Santa Cruz)用于蛋白免疫印迹实验,旨在研究雌激素代谢在该激素诱导的乳腺致癌中的作用。 更多
CYP24A1
cytochrome P450 family 24 subfamily A member 1
总数:1
Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 至该文献
为了说明在膀胱中维生素D可以诱导一种人类抗菌肽cathelicidin的表达,采用了Sigman Aldrich公司的抗CYP24A1(1:150)多克隆抗体进行免疫细胞化学实验。
CYP27B1
cytochrome P450 family 27 subfamily B member 1
总数:1
Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 至该文献
为了说明在膀胱中维生素D可以诱导一种人类抗菌肽cathelicidin的表达,采用了Santa Cruz公司的抗CYP27B1(D-20,1:200)多克隆抗体进行免疫细胞化学实验。
CYP2A13
cytochrome P450 family 2 subfamily A member 13
CYP2A6
cytochrome P450 family 2 subfamily A member 6
总数:1
CYP2A13 in human respiratory tissues and lung cancers: an immunohistochemical study with a new peptide-specific antibody. 2006 至该文献
CYP2A7
cytochrome P450 family 2 subfamily A member 7
CYP2C8
cytochrome P450 family 2 subfamily C member 8
总数:3
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. 2009 至该文献
为了介绍在急性肾损伤时线粒体动力学的一种快速调节,使用了BD Biosciences ― Pharmingen公司的单克隆抗cytochrome c抗体来进行免疫组化实验。 更多
CYP2C9
cytochrome P450 family 2 subfamily C member 9
总数:4
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 至该文献
Cyp2e1
cytochrome P450 family 2 subfamily E member 1
总数:7
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 至该文献
使用牛津大学生物医学研究的抗CYP2E1(1:1000) 抗体进行免疫印迹实验来研究心肌CPR和CPR依赖酶在阿霉素介导的急性心脏毒性中的作用。 更多
CYP2F1
cytochrome P450 family 2 subfamily F member 1
CYP2R1
cytochrome P450 family 2 subfamily R member 1
CYP2S1
cytochrome P450 family 2 subfamily S member 1
CYP2W1
cytochrome P450 family 2 subfamily W member 1
CYP39A1
cytochrome P450 family 39 subfamily A member 1
CYP3A43
cytochrome P450 family 3 subfamily A member 43
CYP3A5
cytochrome P450 family 3 subfamily A member 5
总数:1
Differential mechanism-based inhibition of CYP3A4 and CYP3A5 by verapamil. 2005 至该文献
CYP4A22
cytochrome P450 family 4 subfamily A member 22
CYP4F11
cytochrome P450 family 4 subfamily F member 11
总数:1
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells. 2010 至该文献
为了说明在人角质形成细胞HaCaT中,维甲酸能够通过多条信号通路包括RXR和JNK通路来抑制CYP4F11的表达,使用了Proteintech公司的CYP4F11多抗来进行免疫印记实验。
CYP4F12
cytochrome P450 family 4 subfamily F member 12
CYP4F2
cytochrome P450 family 4 subfamily F member 2
CYP4F22
cytochrome P450 family 4 subfamily F member 22
CYP4F8
cytochrome P450 family 4 subfamily F member 8
CYP7B1
cytochrome P450 family 7 subfamily B member 1
CYP8B1
cytochrome P450 family 8 subfamily B member 1
FMO2
flavin containing dimethylaniline monoxygenase 2
PGIS
prostaglandin I2 synthase
总数:4
Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages. 2005 至该文献
PTGS1
prostaglandin-endoperoxide synthase 1
总数:12
Cyclooxygenase-2 is involved in the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma induced by tumor necrosis factor-alpha. 2009 至该文献
为了证实环氧酶2可以调节胆管癌患者基质金属蛋白酶9的表达上调,使用了Santa Cruz公司的抗COX-1抗体来进行蛋白印迹分析和免疫组化分析。 更多
TBXAS1
thromboxane A synthase 1
总数:3
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. 2009 至该文献
为研究高密度SNP基础的基因型排列分析检测小儿低级星形细胞瘤7q34重复区发现的新型BRAF融合基因,采用了Abcam公司的抗TBXAS1抗体进行蛋白质印迹试验。 更多