Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)

基因

试剂

文献样例

产品评述样例

组织蛋白酶G (cathepsin G)

颗粒酶H (granzyme H)

IGF-1 (IGF-1)
insulin like growth factor 1

总数:13

The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 至该文献

为研究胰岛素生长因子在骨髓瘤细胞生长过程中所发挥的作用，及其受体表达与骨髓瘤患者预后的相关性，将Abcam公司提供的兔抗胰岛素样生长因子1抗体用于蛋白免疫印迹实验中。更多

IGFALS
insulin like growth factor binding protein acid labile subunit

IGFBP-3 (IGFBP-3)
insulin like growth factor binding protein 3

总数:17

IGFBP3 colocalizes with and regulates hypocretin (orexin). 2009 至该文献

为研究胰岛素样生长因子结合蛋白3与食欲素间的相关性，将Santa Cruz提供的多克隆抗人胰岛素样生长因子结合蛋白3抗体用于蛋白免疫印迹实验中。更多

IGFBP2
insulin like growth factor binding protein 2

总数:2

A 14-kDa cathepsin L-derived carboxyl IGFBP-2 fragment is sequestered by cultured rat ileal crypt cells. 2005 至该文献

Santa Cruz Biotechnology的IGFBP2抗体被用于蛋白质印迹和免疫组化实验，来证明在回肠腺管细胞中地塞米松能够改变对IGFBP-2的蛋白水解调控。更多

IGFBP5
insulin like growth factor binding protein 5

总数:1

Interaction of insulin-like growth factor II (IGF-II) with multiple plasma proteins: high affinity binding of plasminogen to IGF-II and IGF-binding protein-3. 2005 至该文献

IGFBP6
insulin like growth factor binding protein 6

总数:1

Proteomic identification of insulin-like growth factor-binding protein-6 induced by sublethal H2O2 stress from human diploid fibroblasts. 2005 至该文献

在免疫印迹实验中使用了Santa Cruz Biotechnology公司的多克隆IGFBP-6抗体（1:200稀释）用于验证在体内外IGFBP-6是一个细胞退化和损伤的敏感的生物标志。

KLK1
kallikrein 1

KLK13
kallikrein related peptidase 13

KLK2
kallikrein related peptidase 2

基质金属蛋白酶-1 (MMP-1)
matrix metallopeptidase 1

总数:13

Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 至该文献

为研究CD147促使成肌纤维细胞分化在组织变构中的作用，采用了Calbiochem公司的抗MMP-1单克隆抗体进行蛋白质印迹试验。更多

基质金属蛋白酶-2 (MMP-2)
matrix metallopeptidase 2

总数:37

Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 至该文献

为了研究MMP2表达在人胰腺细胞系BxPC-3的浸润及黏附中的作用，采用了Santa Cruz公司的MMP-2单克隆抗体用于免疫印迹实验。更多

PAPPA2
pappalysin 2

纤溶酶原 (plasminogen)

总数:4

Borrelia burgdorferi infection-associated surface proteins ErpP, ErpA, and ErpC bind human plasminogen. 2009 至该文献

为研究伯氏疏螺旋体感染时表面蛋白ErpP,ErpA和ErpC与人类血浆酶原的结合，采用了Novus Biologicals公司的羊抗人plasminogen抗体进行酶联免疫吸附试验。更多

妊娠相关血浆蛋白A (pregnancy associated plasma protein A)
pappalysin 1

前列腺特异抗原 (prostate specific antigen)
kallikrein related peptidase 3

总数:18

Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. 2008 至该文献