Regulation of cholesterol biosynthesis by SREBP (SREBF)
基因
试剂
文献样例
产品评述样例
ACACA
acetyl-CoA carboxylase alpha
总数:17
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 至该文献
为了研究AMP激活的蛋白激酶调节细胞对代谢压力的反应的机制，使用了Upstate Biotechnologies公司的抗ACC1 S79ph 抗体来进行免疫印迹分析。 更多
ACACB
acetyl-CoA carboxylase beta
CYP51A1
cytochrome P450 family 51 subfamily A member 1
脂肪酸合成酶 (fatty acid synthase)
总数:6
Fatty acid synthase expression in cutaneous melanocytic neoplasms. 2005 至该文献
FDPS
farnesyl diphosphate synthase
GGPS1
geranylgeranyl diphosphate synthase 1
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
总数:1
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 至该文献
为了研究内含子区的miRNA miR-33在胆固醇代谢调节中的功能，使用了Santa Cruz Biotechnology公司的抗HMGCR多克隆抗体来进行免疫印迹分析。
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
IDI1
isopentenyl-diphosphate delta isomerase 1
总数:1
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. 2009 至该文献
为了研究知母皂甙AIII对肿瘤细胞造成细胞毒性的机制，使用了Protein Tech Group公司的抗IDI1抗体来进行蛋白印迹分析。
INSIG1
insulin induced gene 1
总数:1
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. 2009 至该文献
为了研究知母皂甙AIII对肿瘤细胞造成细胞毒性的机制，使用了Biovision公司的抗INSIG-1抗体来进行蛋白印迹分析。
INSIG2
insulin induced gene 2
KPNB1
karyopherin subunit beta 1
总数:7
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies. 2010 至该文献
为了说明WRAP53是形成卡恰尔身体的必要因素并且能够将SMN复合体定位到卡恰尔身体，使用了Santa Cruz Biotechnology公司的alpha-importin beta鼠抗(sc-137016)来进行免疫印记，免疫沉淀和免疫细胞组化实验。 更多
long chain fatty acyl elongase
ELOVL fatty acid elongase 6
LSS
lanosterol synthase
MBTPS1
membrane bound transcription factor peptidase, site 1
MBTPS2
membrane bound transcription factor peptidase, site 2
甲羟戊酸激酶 (mevalonate kinase)
mevalonate pyrophosphate decarboxylase
mevalonate diphosphate decarboxylase
NF-YA (NF-YA)
nuclear transcription factor Y subunit alpha
总数:13
Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients. 2009 至该文献
为了研究马铃薯球蛋白tuberin和8－羟基鸟嘌呤糖苷酶（OGG1）在结节性硬化症病人发病机制中的作用，采用了Santa Cruz公司生产的兔源性NF-YA抗体进行免疫印迹实验。 更多
phosphomevalonate kinase
Ran
RAN, member RAS oncogene family
总数:17
A role for PVRL4-driven cell-cell interactions in tumorigenesis. 2013 至该文献
为了研究PVRL4在肿瘤进展过程中的作用，BD Biosciences的小鼠抗RAN抗体被用于进行蛋白质免疫印迹实验。 更多
SAR1B
secretion associated Ras related GTPase 1B
SC5D
sterol-C5-desaturase
SEC23A
Sec23 homolog A, COPII coat complex component
总数:3
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 至该文献
SEC24A
SEC24 homolog A, COPII coat complex component
SEC24B
SEC24 homolog B, COPII coat complex component
SEC24C
SEC24 homolog C, COPII coat complex component
SEC24D
SEC24 homolog D, COPII coat complex component
奥皮茨综合征 (Smith Lemli Opitz syndrome)
7-dehydrocholesterol reductase
Sp1转录因子 (Sp1)
Sp1 transcription factor
总数:70
Sp1 and KLF15 regulate basal transcription of the human LRP5 gene. 2010 至该文献
为了研究Sp1和KLF15对人类LRP5基因常转录的调节作用，采用了Santa Cruz的抗Sp1抗体进行染色体免疫共沉淀试验。 更多
squalene epoxidase
squalene synthase
farnesyl-diphosphate farnesyltransferase 1
SREBF2
sterol regulatory element binding transcription factor 2
总数:3
Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. 2005 至该文献
SREBP cleavage activating protein
SREBF chaperone
总数:1
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 至该文献
为了研究内含子区的miRNA miR-33在胆固醇代谢调节中的功能，使用了Santa Cruz Biotechnology公司的抗SCAP多克隆抗体来进行免疫印迹分析。
SREBP-1 (SREBP-1)
sterol regulatory element binding transcription factor 1
总数:11
Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells. 2009 至该文献
为了研究在骨骼肌细胞中β-连环蛋白信号的活化能够提高对胰岛素的敏感性的机制，采用了NeoMarkers公司的单克隆SREBP-1抗体，进行了蛋白质印记实验。 更多
TM7SF2
transmembrane 7 superfamily member 2