Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
基因
试剂
文献样例
产品评述样例
ABCA1
ATP binding cassette subfamily A member 1
总数:10
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 至该文献
为了研究内含子区的miRNA miR-33在胆固醇代谢调节中的功能,使用了Abcam公司的小鼠抗ABCA1单克隆抗体来进行免疫印迹分析。 更多
ABCB4
ATP binding cassette subfamily B member 4
总数:1
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 至该文献
ACSL1
acyl-CoA synthetase long chain family member 1
AGT
angiotensinogen
总数:6
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. 2008 至该文献
ANGPTL4
angiopoietin like 4
总数:1
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. 2005 至该文献
载脂蛋白A1 (apoA-I)
apolipoprotein A1
总数:13
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 至该文献
为了在一个转基因小鼠模型中研究载脂蛋白成员的不同作用,采用 Abcam公司的兔多克隆抗apoA-I抗体产品(1:10,000),进行了免疫印迹实验。 更多
CARM1
coactivator associated arginine methyltransferase 1
总数:3
The C-terminal domain of RNA polymerase II is modified by site-specific methylation. 2011 至该文献
为了揭示RNA聚合酶II羧基端结构域甲基化能够促进一些RNA的表达,采用Bethyl Laboratories的抗CARM1抗体进行免疫细胞化学试验。 更多
CBP
CREB binding protein
总数:38
Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. 2009 至该文献
Santa Cruz Biotechnology CBP 抗体用于免疫印迹来证明HDAC抑制剂能通过Fox01乙酰化-Bim通路诱导细胞凋亡 更多
CD36
CD36 molecule
总数:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 至该文献
为了说明在TRl信号通路的介导下间质干细胞能被极化成两种截然不同的表型,采用了eBiosciences公司的抗CD36抗体进行流式细胞术和免疫细胞化学实验。 更多
CHD9
chromodomain helicase DNA binding protein 9
结缔组织生长因子 (connective tissue growth factor)
cellular communication network factor 2
总数:11
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 至该文献
为了研究c-Abl酪氨酸激酶在调控心脏的生长和发育中的作用,采用了Santa Cruz Biotechnologies公司的抗CTGF抗体(1:2,000),进行了免疫印迹实验 更多
CPT2
carnitine palmitoyltransferase 2
总数:1
Coimmunoprecipitation of FAT/CD36 and CPT I in skeletal muscle increases proportionally with fat oxidation after endurance exercise training. 2006 至该文献
Santa Cruz Biotechnology的抗CPT I多克隆抗体被用于免疫沉淀反应去将CPT I从人类骨骼肌中分离出来。
Cyp1A1
cytochrome P450 family 1 subfamily A member 1
总数:15
Potential therapeutic significance of increased expression of aryl hydrocarbon receptor in human gastric cancer. 2009 至该文献
为确定芳香烃受体在胃癌发生过程中的功能性意义,并探讨其在胃癌治疗中可能发挥的作用,将Chemicon International提供的抗CYP 1A1抗体(AB1258)用于蛋白免疫印迹实验中。 更多
FABP1
fatty acid binding protein 1
总数:1
Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury. 2010 至该文献
为研究L-FABP蛋白在急性肾损伤(AKI)中的预后作用,采用了R&D Systems公司的羊抗人L-FABP多克隆抗体进行蛋白质印迹试验。
FHL2
four and a half LIM domains 2
总数:4
Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway. 2009 至该文献
运用Santa Cruz Biotechnology 公司的抗FHL2抗体,进行免疫印迹实验以研究人FHL1家族成员在TGF-β相似信号通路中抑制肿瘤细胞生长的作用。 更多
GRHL1
grainyhead like transcription factor 1
HDAC3
histone deacetylase 3
总数:21
Histone deacetylase complexes promote trinucleotide repeat expansions. 2012 至该文献
为了鉴定能够促进三核苷酸重复序列扩增的新组蛋白脱乙酰酶复合物,采用了Santa Cruz Biotechnology公司抗组蛋白脱乙酰酶3抗体进行了免疫印迹实验。 更多
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
总数:1
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 至该文献
为了研究内含子区的miRNA miR-33在胆固醇代谢调节中的功能,使用了Santa Cruz Biotechnology公司的抗HMGCR多克隆抗体来进行免疫印迹分析。
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2
MED1
mediator complex subunit 1
总数:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 至该文献
为了研究即刻早期反应基因表达调控因MED23突变而被破坏并导致智力障碍,采用Santa Cruz的多抗MED1抗体进行ChIP和蛋白印迹实验。 更多
mSin3A
SIN3 transcription regulator family member A
总数:15
Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex. 2010 至该文献
为了研究组蛋白去乙酰酶抑制剂对Sin3复合物的亚基ING2作用,采用Abcam抗Sin3a的抗体进行免疫印迹实验。 更多
NCOA2
nuclear receptor coactivator 2
总数:6
Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. 2006 至该文献
NCOA6
nuclear receptor coactivator 6
总数:1
Characterization of activating signal cointegrator-2 as a novel transcriptional coactivator of the xenobiotic nuclear receptor constitutive androstane receptor. 2005 至该文献
NCoR
nuclear receptor corepressor 1
总数:14
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 至该文献
为了说明IRF5同HATs和HDACs一起调控促炎细胞因子的转录水平表达,使用了Santa Cruz Biotechnology公司的抗核受体辅助抑制因子抗体进行蛋白印迹实验。 更多
NF-YA (NF-YA)
nuclear transcription factor Y subunit alpha
总数:13
Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients. 2009 至该文献
为了研究马铃薯球蛋白tuberin和8-羟基鸟嘌呤糖苷酶(OGG1)在结节性硬化症病人发病机制中的作用,采用了Santa Cruz公司生产的兔源性NF-YA抗体进行免疫印迹实验。 更多
NPAS2
neuronal PAS domain protein 2
总数:1
The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response. 2008 至该文献
为了研究日节律基因NPAS2作为可能的肿瘤抑制基因在DNA损伤中的作用,采用了Santa Cruz的兔多抗NPAS2抗体进行免疫印迹实验。
NRF1
nuclear respiratory factor 1
总数:1
Endurance exercise as a countermeasure for aging. 2008 至该文献
为了研究与年龄相关的一些功能障碍是否因为衰老所致还是因为缺乏锻炼 ,采用了SantaCruz公司的NRF-1抗体,进行蛋白质印记实验。
PLIN2
perilipin 2
总数:2
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 至该文献
为了研究高效肝炎C病毒颗粒的形成条件,采用了Santa Cruz公司的抗ADRP抗体进行蛋白免疫印迹实验。 更多
PPAR
peroxisome proliferator activated receptor alpha
总数:9
Integration of microRNA miR-122 in hepatic circadian gene expression. 2009 至该文献
为了研究综合microRNA mir-122在肝脏中的交替表达,采用Abcam公司兔多克隆抗体PPARβ/δ ,进行免疫沉淀实验。 更多
RGL
ral guanine nucleotide dissociation stimulator like 1
RXRalpha
retinoid X receptor alpha
总数:14
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells. 2010 至该文献
为了说明在人角质形成细胞HaCaT中,维甲酸能够通过多条信号通路包括RXR和JNK通路来抑制CYP4F11的表达,使用了Santa Cruz Biotechnology公司的RXRs多抗来进行免疫印记实验。 更多
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMRT
nuclear receptor corepressor 2
总数:11
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 至该文献
为了说明IRF5同HATs和HDACs一起调控促炎细胞因子的转录水平表达,使用了Affinity Bioreagents公司的抗SMRT抗体进行蛋白印迹实验。 更多
Sp1转录因子 (Sp1)
Sp1 transcription factor
总数:70
Sp1 and KLF15 regulate basal transcription of the human LRP5 gene. 2010 至该文献
为了研究Sp1和KLF15对人类LRP5基因常转录的调节作用,采用了Santa Cruz的抗Sp1抗体进行染色体免疫共沉淀试验。 更多
SRC-1 (SRC-1)
nuclear receptor coactivator 1
总数:12
The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors. 2009 至该文献
为了研究p160的共激活剂PAS-B是怎样通过甲状腺激素受体识别特异亚型并进行调节,采用了Affinity BioReagent公司的anti-SRC1抗体,进行免疫共沉淀反应。 更多
SREBF2
sterol regulatory element binding transcription factor 2
总数:3
Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. 2005 至该文献
SREBP-1 (SREBP-1)
sterol regulatory element binding transcription factor 1
总数:11
Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells. 2009 至该文献
为了研究在骨骼肌细胞中β-连环蛋白信号的活化能够提高对胰岛素的敏感性的机制,采用了NeoMarkers公司的单克隆SREBP-1抗体,进行了蛋白质印记实验。 更多
SULT2A1
sulfotransferase family 2A member 1
总数:2
Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre- and postnatal human liver. 2006 至该文献
TGS1
trimethylguanosine synthase 1
总数:1
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 至该文献
为了研究RNA聚合酶II在转录拼接中的延长作用使用了Mercury公司的鼠抗2,2,7-trimethylguanosine (TMG)抗体来进行免疫沉淀作用。
TRB3
tribbles pseudokinase 3
总数:2
Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis. 2008 至该文献
为了研究蛋白合成受抑制后mTORC1信号途径的反应,使用了EMD Chemicals公司的抗TRB3抗体来进行蛋白印迹分析。 更多
TXNRD1
thioredoxin reductase 1
总数:2
Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities. 2009 至该文献
为了说明脂联素单倍不足可以通过抑制PTEN抑癌因子的活性和激活PI3K/Akt信号通路来促进乳腺肿瘤的发生,使用了Santa Cruz Biotechnology公司的抗TrxR1抗体来进行蛋白印迹实验。 更多