S Phase

基因

试剂

文献样例

产品评述样例

CCNA1
cyclin A1

总数:14

CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase. 2009 至该文献

使用Santa Cruz生物公司的抗cyclin A抗体进行免疫印迹来研究细胞周期过程中调钙素调节Ect2, MgcRacGAP, 和 MKLP1 表达的作用更多

CCNE2
cyclin E2

总数:4

Polycomb protein SCML2 regulates the cell cycle by binding and modulating CDK/CYCLIN/p21 complexes. 2013 至该文献

为了研究 CYCE2 与SCML2之间的相互作用，采用Epitomics 公司的CYCE2 抗体进行western Blot 检测。更多

CCNH
cyclin H

总数:3

Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor. 2005 至该文献

为研究人牙本质基质蛋白1(Dmp1)在Ras-Raf-Arf信号通路传导中的作用，采用Santa Cruz生产的cyclin H抗体用于免疫印迹实验。更多

CDC25A
cell division cycle 25A

总数:10

Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways. 2009 至该文献

为了说明肿瘤坏死因子相关凋亡诱导配体可以通过将组蛋白H2AX和Chk2磷酸化来激活DNA损伤反应，使用了Santa Cruz Biotechnology公司的抗Cdc25A抗体进行蛋白印迹实验。更多

CDC25B
cell division cycle 25B

总数:1

Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. 2005 至该文献

CDC45
cell division cycle 45

CDC6
cell division cycle 6

总数:9

Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献

为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用，采用了Santa Cruz的抗人Cdc6抗体进行免疫沉淀实验。更多

CDCA5
cell division cycle associated 5

CDK2
cyclin dependent kinase 2

总数:53

Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献

为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用，采用了Santa Cruz的抗人Cdk2抗体进行免疫印迹实验。更多

Cdk4
cyclin dependent kinase 4

总数:44

Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. 2010 至该文献

为了研究脆性X智力低下蛋白在的功能对成人神经干细胞/神经祖细胞的增殖和分化所起的调控作用，使用了Millipore公司的抗CDK4抗体来进行蛋白印迹分析。更多

cdk7
cyclin dependent kinase 7

总数:8

MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 至该文献

为了研究即刻早期反应基因表达调控因MED23突变而被破坏并导致智力障碍，采用Santa Cruz的多抗CDK7抗体进行ChIP和蛋白印迹实验。更多

CDT1
chromatin licensing and DNA replication factor 1

总数:3

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 至该文献

为了说明Skp2参与非p19Arf-p53途径的细胞衰老，使用了Proteintech Group公司的Cdt1抗体来进行免疫印记实验。更多

CKS1B
CDC28 protein kinase regulatory subunit 1B

总数:1

Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. 2005 至该文献

Cul1
cullin 1

总数:12

Mediator acts upstream of the transcriptional activator Gal4. 2012 至该文献

为了研究Mediator复合物是如何起始Gal4基因转录的，采用了Abcam公司的抗Cul1抗体进行了免疫共沉淀实验。更多

周期一 (cyclin A)
cyclin A2

总数:39

Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression. 2010 至该文献

为了研究Pcid2通过调控MAD2表达在B细胞生存中发挥的决定性作用，采用了Santa Cruz Biotechnology公司的抗cyclin A单克隆抗体进行免疫印迹试验。更多

细胞周期蛋白D1 (cyclin D1)

总数:123

The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 至该文献

为了研究ING1a诱导细胞衰老的机制，使用圣克鲁斯生物技术公司的抗Cyclin D1抗体，进行蛋白印迹试验。更多

周期蛋白E (cyclin E)
cyclin E1

总数:55

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 至该文献

为了研究在管腔乳腺癌中雌激素敏感性以及抗雌激素抗性的获得，采用了Santa Cruz 的抗cyclin E 抗体进行了western blot实验。更多

DNA连接酶I (DNA ligase I)
DNA ligase 1

总数:4

Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex. 2006 至该文献

DNA2
DNA replication helicase/nuclease 2

ESCO1
establishment of sister chromatid cohesion N-acetyltransferase 1

ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2

FEN1
flap structure-specific endonuclease 1

总数:2

Flap endonuclease 1 is overexpressed in prostate cancer and is associated with a high Gleason score. 2006 至该文献

为了研究人初级前列腺癌中结构特异的核酸内切酶(FEN-1)得表达和潜在的临床意义，采用了Novocastra公司的多克隆抗FEN-1抗体进行免疫组织化学分析更多

FZR1
fizzy and cell division cycle 20 related 1

总数:2

Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis. 2008 至该文献

E-cadherin基因（Cdh1）抗体（Calbiochem公司生产）可用于免疫印迹实验，来研究Cdh1/APC在肿瘤发生过程中的作用。更多

gankyrin
proteasome 26S subunit, non-ATPase 10

GINS2
GINS complex subunit 2

MCM2
minichromosome maintenance complex component 2

总数:8

Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. 2006 至该文献

MCM3
minichromosome maintenance complex component 3

总数:5

Orc1 controls centriole and centrosome copy number in human cells. 2009 至该文献

为了说明人类细胞中的中心体和中心粒的拷贝数是由Orc1调控的，使用了Santa Cruz Biotechnology公司的兔多克隆抗MCM3抗体进行蛋白印迹实验。更多

MCM4
minichromosome maintenance complex component 4

总数:1

The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. 2010 至该文献

为了研究ETG1在调控内源性DNA应激中的作用，使用了Acbam公司的抗MCM4抗体，进行了免疫印迹实验。

MCM5
minichromosome maintenance complex component 5

总数:2

The DNA replication factor MCM5 is essential for Stat1-mediated transcriptional activation. 2005 至该文献

MCM6
minichromosome maintenance complex component 6

总数:2

The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair. 2010 至该文献

为了研究ETG1在调控内源性DNA应激中的作用，使用了Acbam公司的抗MCM6抗体，进行了免疫印迹实验。更多

MCM7
minichromosome maintenance complex component 7

总数:6

Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献

为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用，采用了Santa Cruz的抗人Mcm7抗体进行免疫印迹实验。更多

MCM8
minichromosome maintenance 8 homologous recombination repair factor

MNAT1
MNAT1 component of CDK activating kinase

总数:2

Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". 2006 至该文献

ORC1
origin recognition complex subunit 1

总数:1

p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation. 2005 至该文献

ORC2
origin recognition complex subunit 2

总数:7

Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献

为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用，采用了Santa Cruz的抗人Orc2抗体进行免疫印迹实验。更多

ORC3
origin recognition complex subunit 3

ORC4
origin recognition complex subunit 4

总数:1

Orc1 controls centriole and centrosome copy number in human cells. 2009 至该文献

为了说明人类细胞中的中心体和中心粒的拷贝数是由Orc1调控的，使用了Abcam公司的羊多克隆抗Orc4抗体进行蛋白印迹实验。

ORC5
origin recognition complex subunit 5

ORC6
origin recognition complex subunit 6

p21
cyclin dependent kinase inhibitor 1A

总数:178

Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1. 2012 至该文献

为了研究阿霉素抑制肿瘤生长的机制，采用了Abcam的兔抗p21抗体，进行免疫印迹实验。更多

p27
cyclin dependent kinase inhibitor 1B

总数:118

Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. 2012 至该文献

为了研究p53依赖的细胞增殖和存活能够被atg7调控，采用了BD Pharmingen的抗p27CDKN1B抗体进行蛋白印迹实验。更多

p44S10
proteasome 26S subunit, non-ATPase 6

PA200
proteasome activator subunit 4

总数:1

Transformation of the proteasome with age-related macular degeneration. 2007 至该文献

为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体调节蛋白PA200抗体,进行了蛋白质印迹实验.

增殖细胞核抗原 (PCNA)
proliferating cell nuclear antigen

总数:84

A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 至该文献

为了研究DNA损伤应答过程中RHINO对ATR活化的重要作用，采用Santa Cruz的抗PCNA抗体进行蛋白印迹实验。更多

PDS5A
PDS5 cohesin associated factor A

PDS5B
PDS5 cohesin associated factor B

POLA1
DNA polymerase alpha 1, catalytic subunit

总数:1

p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum. 2012 至该文献

为了研究p180对一些能够不依赖核糖体实现在内质网上定位的mRNA的作用，采用了Sigma公司的抗p180抗体进行免疫印迹试验。

POLA2
DNA polymerase alpha 2, accessory subunit

POLD1
DNA polymerase delta 1, catalytic subunit

总数:2

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. 2012 至该文献

为了研究DNA代谢和基因组完整性由MMS19维持，采用了Proteintech的抗POLD1抗体进行蛋白印迹和免疫沉淀实验。更多

POLD2
DNA polymerase delta 2, accessory subunit

POLD3
DNA polymerase delta 3, accessory subunit

POLD4
DNA polymerase delta 4, accessory subunit

POLE
DNA polymerase epsilon, catalytic subunit

POLE2
DNA polymerase epsilon 2, accessory subunit

PRIM2
DNA primase subunit 2

PSF1
GINS complex subunit 1

PSMA1
proteasome 20S subunit alpha 1

总数:9

Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 至该文献

PSMA3
proteasome 20S subunit alpha 3

总数:3

Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 至该文献

为了研究内着丝粒是如何建立的和CPC复合物是如何靶向到此位点的机制，使用了Santa Cruz Biotechnology公司的抗Psc3抗体来进行染色质免疫沉淀实验。更多

PSMA4
proteasome 20S subunit alpha 4

总数:3

Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献

为了研究免疫蛋白酶体在多发性硬化发病机制的作用，采用Affinity-Biomol International小鼠抗人的20S proteasome subunit alpha4单克隆抗体进行免疫组织化学试验。更多

PSMA7
proteasome 20S subunit alpha 7

总数:4

Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 至该文献

为了在内质网相关蛋白的降解途径（ERAD）中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能，使用了Enzo Life Sciences公司的抗体alpha7来进行免疫印迹分析。更多

PSMA8
proteasome 20S subunit alpha 8

PSMB1
proteasome 20S subunit beta 1

总数:2

Transformation of the proteasome with age-related macular degeneration. 2007 至该文献

为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体亚基β1抗体,进行了蛋白质印迹实验. 更多

PSMB10
proteasome 20S subunit beta 10

PSMB11
proteasome subunit beta 11

PSMB4
proteasome 20S subunit beta 4

PSMB5
proteasome 20S subunit beta 5

总数:1

Transformation of the proteasome with age-related macular degeneration. 2007 至该文献

为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体亚基β5抗体,进行了蛋白质印迹实验.

PSMB6
proteasome 20S subunit beta 6

PSMB7
proteasome 20S subunit beta 7

PSMB8
proteasome 20S subunit beta 8

总数:3

Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献

为了研究免疫蛋白酶体在多发性硬化发病机制的作用，采用Affinity-Biomol International抗LMP7抗体进行免疫组织化学试验。更多

PSMB9
proteasome 20S subunit beta 9

总数:2

Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献

为了研究免疫蛋白酶体在多发性硬化发病机制的作用，采用Affinity-Biomol International抗LMP2抗体进行免疫组织化学试验。更多

PSMC1
proteasome 26S subunit, ATPase 1

PSMC4
proteasome 26S subunit, ATPase 4

总数:8

Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 至该文献

为了研究在帕金森疾病模型中雷怕霉素对神经元的保护作用，采用了Cell Signaling Technology的抗phospho-Ser235/236-S6抗体进行免疫细胞化学试验。更多

PSMC6
proteasome 26S subunit, ATPase 6

总数:1

Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 至该文献

PSMD1
proteasome 26S subunit, non-ATPase 1

PSMD11
proteasome 26S subunit, non-ATPase 11

PSMD12
proteasome 26S subunit, non-ATPase 12

PSMD13
proteasome 26S subunit, non-ATPase 13

PSMD14
proteasome 26S subunit, non-ATPase 14

PSMD2
proteasome 26S subunit, non-ATPase 2

总数:1

HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 至该文献

为了说明hHR23A介导的Vpr与蛋白酶体的互作在病毒复制过程中有重要作用，使用了Calbiochem公司的19S蛋白酶体S2亚基的兔多抗来进行免疫印记实验。

PSMD4
proteasome 26S subunit, non-ATPase 4

总数:3

HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 至该文献

为了说明hHR23A介导的Vpr与蛋白酶体的互作在病毒复制过程中有重要作用，使用了Calbiochem公司的19S蛋白酶体S5a亚基的兔多抗来进行免疫印记实验。更多

PSMD5
proteasome 26S subunit, non-ATPase 5

PSMD7
proteasome 26S subunit, non-ATPase 7

PSMD8
proteasome 26S subunit, non-ATPase 8

PSMD9
proteasome 26S subunit, non-ATPase 9

总数:13

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 至该文献

为了研究在管腔乳腺癌中雌激素敏感性以及抗雌激素抗性的获得，采用了Santa Cruz 的抗p27抗体进行了western blot实验。更多

PSME1
proteasome activator subunit 1

总数:3

Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献

为了研究免疫蛋白酶体在多发性硬化中的作用，采用Affinity-Biomol International兔抗PA28alpha多克隆抗体进行免疫组织化学试验。更多

PSME2
proteasome activator subunit 2

总数:1

Chronic ethanol feeding affects proteasome-interacting proteins. 2009 至该文献

为了确认长期酒精喂养对蛋白酶体相互作用蛋白表达的影响，采用了BIOMOL公司的抗PA28β抗体进行免疫印迹法实验。

PSME3
proteasome activator subunit 3

PSMF1
proteasome inhibitor subunit 1

RAD21
RAD21 cohesin complex component

总数:2

Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. 2010 至该文献

为了研究cdc6在cdk1和分离酶介导的染色体分离中的作用，采用了Novus的抗人Rad21抗体进行免疫印迹实验。更多

Rb
RB transcriptional corepressor 1

总数:77

LIMD1 is more frequently altered than RB1 in head and neck squamous cell carcinoma: clinical and prognostic implications. 2010 至该文献

为了研究LIMD1和pRB两个蛋白在头颈鳞状细胞癌中的作用，采用了Santa Cruz的兔抗pRB的多克隆IgG抗体进行免疫组织化学试验。更多

RFC1
replication factor C subunit 1

RFC2
replication factor C subunit 2

RFC3
replication factor C subunit 3

RFC5
replication factor C subunit 5

RPA2
replication protein A2

总数:12

ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. 2010 至该文献

为了研究人类I性单纯疱疹病毒感染细胞中，病毒基因表达和复制过程中ATR和ATRIP两者的关系，采用了GeneTex的抗RPA32单克隆抗体进行了细胞免疫荧光实验。更多

RPS27A
ribosomal protein S27a

总数:5

Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 至该文献

为了在内质网相关蛋白的降解途径（ERAD）中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能，使用了Santa Cruz Biotechnology公司的抗体ubiquitin来进行免疫印迹分析。更多

S3
proteasome 26S subunit, non-ATPase 3

Skp1
S-phase kinase associated protein 1

总数:8

APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. 2009 至该文献

Skp2
S-phase kinase associated protein 2

总数:17

Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy. 2009 至该文献

为了在K562细胞中研究CSN对细胞自噬有重要作用，采用Zymed的抗Skp2抗体以1:1000稀释进行蛋白印迹实验。更多

SLD5
GINS complex subunit 4

Smc1
structural maintenance of chromosomes 1A

总数:14

A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. 2011 至该文献

为了研究DNA损伤应答过程中RHINO对ATR活化的重要作用，采用Bethyl的抗SMC1抗体进行蛋白印迹实验。更多

SMC3
structural maintenance of chromosomes 3

STAG1
stromal antigen 1

总数:2

Mutational inactivation of STAG2 causes aneuploidy in human cancer. 2011 至该文献

为了研究人肿瘤细胞中染色体的异倍性与STAG2的失活相关，采用Santa Cruz的抗STAG1抗体进行蛋白印迹实验。更多

STAG2
stromal antigen 2

总数:1

Mutational inactivation of STAG2 causes aneuploidy in human cancer. 2011 至该文献

为了研究人肿瘤细胞中染色体的异倍性与STAG2的失活相关，采用Santa Cruz的抗STAG2抗体进行蛋白印迹和免疫组织化学实验。

UBC
ubiquitin C

总数:7

The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 至该文献

为了研究突触的可塑性，采用了Enzo Life Sciences的抗Ubiquitin的抗体进行了免疫印迹实验。更多

泛肽 (ubiquitin)
ubiquitin B

总数:34

BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 至该文献

为了阐明BCL6和HB-EGF-CTF相互作用，并且这种相互作用可能会引起细胞周期蛋白D2在人胃癌细胞中表达，采用了Cell Signaling Technology公司的小鼠抗泛素单克隆抗体，进行了蛋白质印迹实验。更多

WAPL
WAPL cohesin release factor

WEE1
WEE1 G2 checkpoint kinase

总数:2

Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 至该文献

为了研究FANCM在有丝分裂过程中的降解机制，使用了Santa Cruz Biotechnology公司的兔抗WEE1抗体来进行免疫印迹分析。更多