Rho GTPases介导的信号通路
基因
试剂
文献样例
产品评述样例
alpha 2 巨球蛋白 (alpha 2 macroglobulin)
alpha-2-macroglobulin
总数:1
Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. 2013 至该文献
为了在小鼠模型中研究sFlt-1对于维持无血管感光层的作用,Invitrogen的兔子IgG抗体被用于进行免疫组化实验。
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGAP11B
Rho GTPase activating protein 11B
ARHGAP26
Rho GTPase activating protein 26
总数:1
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. 2008 至该文献
为了研究四旋蛋白TM4SF5在接触抑制和肿瘤发生中的作用,采用ABGENT公司的抗GRAF抗体进行免疫印迹实验。
ARHGAP35
Rho GTPase activating protein 35
总数:3
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma. 2008 至该文献
为了研究四旋蛋白TM4SF5在接触抑制和肿瘤发生中的作用,采用BD Biosciences公司的抗p190RhoGAP抗体进行免疫印迹实验。 更多
ARHGAP4
Rho GTPase activating protein 4
总数:3
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 至该文献
ARHGAP40
Rho GTPase activating protein 40
ARHGDIB
Rho GDP dissociation inhibitor beta
总数:3
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 至该文献
为研究RhoGDI2通过Rho GTPases抑制代谢的作用,采用了Spring Bioscience公司的抗D4-GDI多克隆抗体进行免疫印迹试验。 更多
ARHGEF18
Rho/Rac guanine nucleotide exchange factor 18
ARHGEF7
Rho guanine nucleotide exchange factor 7
总数:1
GM130-dependent control of Cdc42 activity at the Golgi regulates centrosome organization. 2009 至该文献
使用Santa Cruz生物公司的抗-β-PIX 抗体进行免疫印迹实验来研究高尔基体的GM130依赖的Cdc42活性在调节中心体重组过程中的作用。
ARHGEF9
Cdc42 guanine nucleotide exchange factor 9
Bcr
BCR activator of RhoGEF and GTPase
总数:7
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. 2008 至该文献
为了研究Lyn调节慢性粒细胞白血病细胞对imatinib敏感性的机制,使用了Cell Signaling Technology公司的抗酪氨酸磷酸化BCR-ABL抗体来进行免疫印记分析。 更多
cdc42
cell division cycle 42
总数:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 至该文献
为了研究肺部发炎部位slit2对嗜酸性粒细胞和嗜中性粒细胞的影响,采用了Santa Cruz Biotechnology公司的抗Cdc42抗体进行蛋白免疫印迹试验。 更多
DBC2
Rho related BTB domain containing 2
DLC1
DLC1 Rho GTPase activating protein
总数:5
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 至该文献
为了研究DLC1对肿瘤发生过程中血管再生的影响,采用了BD Biosciences抗DLC1单克隆抗体来进行免疫组织化学实验。 更多
ECT2
epithelial cell transforming 2
总数:2
CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase. 2009 至该文献
使用Santa Cruz生物公司的抗Ect2抗体进行免疫印迹来研究细胞周期过程中调钙素调节Ect2, MgcRacGAP, 和 MKLP1 表达的作用 更多
FAM13A
family with sequence similarity 13 member A
FAM13B
family with sequence similarity 13 member B
FGD1
FYVE, RhoGEF and PH domain containing 1
FGD2
FYVE, RhoGEF and PH domain containing 2
FGD4
FYVE, RhoGEF and PH domain containing 4
GRF2
Ras protein specific guanine nucleotide releasing factor 2
MCF2
MCF.2 cell line derived transforming sequence
总数:1
Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1. 2008 至该文献
为了证明Nm23-H1可以通过调节Dbl1的活性负调控细胞迁移和肿瘤转移,采用了Santa Cruz兔抗Dbl-1抗体进行了免疫沉淀和免疫印记实验。
MCF2L
MCF.2 cell line derived transforming sequence like
MYO9B
myosin IXB
总数:1
BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity. 2005 至该文献
NET1
neuroepithelial cell transforming 1
总数:1
The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion. 2009 至该文献
为了研究芳香烃受体对组成性的Vav3表达以及细胞可塑性和迁移的调节,使用了Santa Cruz Biotechnology公司的抗Net1抗体来进行免疫印迹分析。
NGEF
neuronal guanine nucleotide exchange factor
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OCRL
OCRL inositol polyphosphate-5-phosphatase
PIK3R2
phosphoinositide-3-kinase regulatory subunit 2
总数:11
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation. 2009 至该文献
为了研究PIP5K1α在胞外钙诱导的第二信使IP3的生成和角质形成细胞分化中的功能,使用了Millipore公司的抗人p85多克隆抗体来进行免疫印迹分析。 更多
PLEKHG2
pleckstrin homology and RhoGEF domain containing G2
PLEKHG5
pleckstrin homology and RhoGEF domain containing G5
RAC2
Rac family small GTPase 2
总数:3
In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression. 2009 至该文献
为了研究ROR2在淋巴瘤侵润性的作用,采用Proteintech公司的Rac2抗体,进行了蛋白印记实验。 更多
RACGAP1
Rac GTPase activating protein 1
总数:3
Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis. 2010 至该文献
为了研究有丝分裂过程中非催化亚基Mob1是怎样与染色体复合物的相互作用机制,采用了Abcam公司Rac的GTP酶激活蛋白1抗体,进行细胞免疫荧光实验。 更多
RhoA
ras homolog family member A
总数:49
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 至该文献
为了研究沉默RhoA和RhoC的表达对人类结直肠癌体内生长的影响,采用Santa Cruz公司的抗RhoA抗体进行了免疫组织化学实验。 更多
RhoB
ras homolog family member B
总数:10
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 至该文献
为了研究类鼻疽杆菌的CHBP蛋白作为真核细胞的泛素化途径的强抑制剂的功能,使用了Santa Cruz Biotechnology公司的抗RhoB抗体来进行免疫印迹分析。 更多
RhoC
ras homolog family member C
总数:5
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 至该文献
为了研究沉默RhoA和RhoC的表达对人类结直肠癌体内生长的影响,采用Santa Cruz公司的抗RhoC抗体进行了免疫组织化学实验。 更多
RHOD
ras homolog family member D
总数:3
ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth. 2005 至该文献
RHOF
ras homolog family member F, filopodia associated
RhoGDI
Rho GDP dissociation inhibitor alpha
总数:8
Clues to CD2-associated protein involvement in cytokinesis. 2005 至该文献
RHOT2
ras homolog family member T2
总数:1
Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking. 2009 至该文献
为了研究Pink1在调控线粒体运输中的作用,采用了Proteintech Group Inc公司的兔多克隆抗RHOT2抗体产品,进行了免疫印迹实验
RHOU
ras homolog family member U
RLIP76
ralA binding protein 1
总数:2
Mass spectroscopic phosphoprotein mapping of Ral binding protein 1 (RalBP1/Rip1/RLIP76). 2007 至该文献
为了鉴定人类膀胱癌UMUC-3细胞和胚胎肾起源的293T细胞中RalBP1蛋白的14个磷酸化位点,采用了Abnova公司的RalBP1抗体,进行了蛋白质印迹实验。 更多
Sos
SOS Ras/Rac guanine nucleotide exchange factor 1
总数:11
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 至该文献
Santa Cruz的兔Sos-1抗体被用于蛋白质印迹实验,来研究Abi-1在形态发生和突触形成中的作用。 更多
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2
总数:1
The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis. 2005 至该文献
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
总数:1
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 2010 至该文献
为了研究肺部发炎部位slit2对嗜酸性粒细胞和嗜中性粒细胞的影响,采用了Santa Cruz Biotechnology公司的抗是srGAP1抗体进行蛋白免疫印迹试验。
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
STARD13
StAR related lipid transfer domain containing 13
STARD8
StAR related lipid transfer domain containing 8
SYDE1
synapse defective Rho GTPase homolog 1
SYDE2
synapse defective Rho GTPase homolog 2
TAGAP
T cell activation RhoGTPase activating protein
Tiam1
TIAM Rac1 associated GEF 1
总数:6
Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells. 2008 至该文献
为了阐明结肠癌细胞中Rac1与经典Wnt信号通路之间的关系,使用了Santa Cruz Biotechnology公司的Tiam1抗体(C-16)来进行免疫沉淀和染色质沉淀实验。 更多
TRIP10
thyroid hormone receptor interactor 10
总数:1
Cdc42-interacting protein 4 promotes breast cancer cell invasion and formation of invadopodia through activation of N-WASp. 2010 至该文献
为了研究在人肿瘤细胞的中CIP4对细胞的运动能力和侵袭能力的影响,采用了Becton Dickson的抗CIP4抗体进行了免疫细胞化学检测和免疫印迹实验。
VAV3
vav guanine nucleotide exchange factor 3
总数:2
Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer. 2008 至该文献
XPLN
Rho guanine nucleotide exchange factor 3