Wnt介导的通路
基因
试剂
文献样例
产品评述样例
H2BS1
H2B.S histone 1
CKI epsilon
casein kinase 1 epsilon
总数:5
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. 2009 至该文献
为了研究Akt1介导的Skp2的磷酸化引起的Skp2细胞质定位和对APCCdh1参与的Skp2降解的损害,采用了Abgent的抗CKI epsilon抗体进行免疫印迹实验。 更多
14 3 3 protein zeta
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
总数:6
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 至该文献
14-3-3ζ抗体,进行蛋白质印迹实验。 更多
AGO2
argonaute RISC catalytic component 2
总数:4
Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA. 2010 至该文献
为了研究疱疹病毒非编码RNA HSURs在调节宿主细胞microRNA中的功能,使用了Millipore公司的抗Ago2抗体来进行免疫沉淀实验。 更多
AGO3
argonaute RISC catalytic component 3
Akt
AKT serine/threonine kinase 1
总数:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 至该文献
为了研究磷酸肌醇激酶3在调节细胞因子依赖性细胞存活中的作用,采用了Cell Signalling公司的抗磷酸化Ser473Akt抗体进行了免疫印迹试验。 更多
α-衔接蛋白 (alpha-adaptin)
adaptor related protein complex 2 subunit alpha 1
总数:17
FCHo proteins are nucleators of clathrin-mediated endocytosis. 2010 至该文献
为了研究FCHo1和FCHo2蛋白在细胞膜上的clathrin介导的内吞作用中的功能,使用了Transduction Laboratories公司的小鼠抗AP2A1单克隆抗体来进行免疫印迹分析。 更多
AP2A2
adaptor related protein complex 2 subunit alpha 2
总数:5
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 至该文献
运用Sigma公司的抗alpha-Adaptin抗体,进行免疫印迹实验以揭示神经细胞和非神经细胞中赫曼斯基-普德拉克综合征蛋白复合体与磷脂酰肌醇4-激酶二型α的相互作用。 更多
AP2B1
adaptor related protein complex 2 subunit beta 1
总数:5
Death-receptor activation halts clathrin-dependent endocytosis. 2006 至该文献
为了研究死亡受体引发基于网格蛋白的内吞作用以及刺激诱导半胱天冬酶介导的主要网格蛋白组分的剪切,阻止细胞摄取经典的货物转运蛋白―铁传递蛋白,采用了BD Transduction Laboratories公司接头蛋白alpha抗体,进行蛋白质印记实验。 更多
AP2M1
adaptor related protein complex 2 subunit mu 1
总数:2
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. 2006 至该文献
AP2S1
adaptor related protein complex 2 subunit sigma 1
APC
APC regulator of WNT signaling pathway
总数:11
A cell motility screen reveals role for MARCKS-related protein in adherens junction formation and tumorigenesis. 2009 至该文献
为了研究MRP蛋白在粘着连接形成和肿瘤发生过程中起重要作用,采用Calbiochem的APC抗体进行免疫细胞化学实验。 更多
ARRB2
arrestin beta 2
总数:3
Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation. 2006 至该文献
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit
总数:2
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 至该文献
为了阐明c-Myb在MLL相关白血病中的作用,实验使用了Bethyl Laboratories公司的抗Ash2L抗体进行免疫共沉淀。 更多
AXIN1
axin 1
总数:2
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation. 2009 至该文献
为了表明N-钙粘素-轴蛋白-LRP5的反应对Wnt/β-钙粘素信号,成骨蛋白功能及骨形成有负调控作用,使用了Zymed公司的抗轴蛋白抗体进行免疫印迹实验。 更多
AXIN2
axin 2
总数:2
Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. 2010 至该文献
为了研究脆性X智力低下蛋白在的功能对成人神经干细胞/神经祖细胞的增殖和分化所起的调控作用,使用了Cell Signaling公司的抗Axin2抗体来进行蛋白印迹分析。 更多
beta连环蛋白 (beta-catenin)
catenin beta 1
总数:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 至该文献
为了研究端粒酶受Wnt/beta-catenin信号调控,采用了Millipore的抗beta-catenin抗体进行ChIP实验。 更多
BRG1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
总数:13
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. 2011 至该文献
为了研究SWI/SNF在潜伏期HIV LTR转录激活前后的调节作用,采用了Abcam SMARCB4进行了蛋白质免疫印迹实验。 更多
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
总数:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 至该文献
为了研究FANCM在有丝分裂过程中的降解机制,使用了Zymed Laboratories的小鼠抗β-TRCP抗体来进行免疫印迹分析。 更多
c-Myc (c-Myc)
MYC proto-oncogene, bHLH transcription factor
总数:235
Regulation of early adipose commitment by Zfp521. 2012 至该文献
为了研究Zfp521在决定成脂细胞和成骨细胞之间的转换的调节性作用,使用了Santa Cruz Biotechnology的抗MYC抗体来进行免疫印迹和免疫沉淀实验。 更多
CAMK2A
calcium/calmodulin dependent protein kinase II alpha
总数:13
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. 2009 至该文献
为了研究CaMKII在调控血压过载诱导的小鼠心肌肥厚到心脏衰竭中的作用,采用了Affinity Bioreagents公司的抗磷酸化CaMKII抗体产品 ,进行了免疫印迹实验 更多
CBP
CREB binding protein
总数:38
Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment. 2009 至该文献
Santa Cruz Biotechnology CBP 抗体用于免疫印迹来证明HDAC抑制剂能通过Fox01乙酰化-Bim通路诱导细胞凋亡 更多
CBY1
chibby family member 1, beta catenin antagonist
网格蛋白重链 (Clathrin Heavy Chain)
clathrin heavy chain
总数:28
Stapled Golgi cisternae remain in place as cargo passes through the stack. 2013 至该文献
为了研究高尔基体介导的蛋白转运机制,Millipore的兔抗网格蛋白抗体被用于进行免疫电镜实验。 更多
CLTA
clathrin light chain A
总数:5
Strain-associated variations in abnormal PrP trafficking of sheep scrapie. 2009 至该文献
为了研究株系变化对羊痒痒症的PrP蛋白运输通路的影响,使用了Sigma-Aldrich公司的抗clathrin轻链单克隆抗体来进行免疫组化实验。 更多
CSNK1A1
casein kinase 1 alpha 1
总数:5
Protein kinase CK1alpha regulates mRNA binding by heterogeneous nuclear ribonucleoprotein C in response to physiologic levels of hydrogen peroxide. 2005 至该文献
CSNK2A1
casein kinase 2 alpha 1
总数:9
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 至该文献
为了研究NF-kB转录因子在白介素1诱导的C/EBPδ和APP基因表达中的功能,使用了Santa Cruz Biotechnology公司的抗CK2 alpha抗体来进行免疫印迹分析。 更多
CSNK2A2
casein kinase 2 alpha 2
总数:4
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. 2010 至该文献
为了研究NF-kB转录因子在白介素1诱导的C/EBPδ和APP基因表达中的功能,使用了Santa Cruz Biotechnology公司的抗CK2 alpha'抗体来进行免疫印迹分析。 更多
CSNK2B
casein kinase 2 beta
总数:2
CK2beta is expressed in endometrial carcinoma and has a role in apoptosis resistance and cell proliferation. 2009 至该文献
为了研究CK2B在子宫内膜癌中抑制凋亡和促进细胞增殖的作用,采用了Santa Cruz的抗CK2B抗体进行免疫印迹和免疫组化实验。 更多
CtBP1
C-terminal binding protein 1
总数:4
Loss of full length CtBP1 expression enhances the invasive potential of human melanoma. 2009 至该文献
CUL3
cullin 3
总数:4
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. 2010 至该文献
为了研究类鼻疽杆菌的CHBP蛋白作为真核细胞的泛素化途径的强抑制剂的功能,使用了Santa Cruz Biotechnology公司的抗Cul3抗体来进行免疫印迹分析。 更多
DAAM1
dishevelled associated activator of morphogenesis 1
DACT1
dishevelled binding antagonist of beta catenin 1
DKK1
dickkopf WNT signaling pathway inhibitor 1
总数:5
Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer. 2008 至该文献
为了考察Dickkopfs (Dkks)和Kremen2 (Krm2)在胃肠道癌症中表达的变化,使用了Abcam公司的抗DKK-1的山羊抗人抗体进行了免疫组化实验。 更多
DKK2
dickkopf WNT signaling pathway inhibitor 2
总数:2
EWS/ETS regulates the expression of the Dickkopf family in Ewing family tumor cells. 2009 至该文献
为研究EWS/ETS对尤文氏肿瘤细胞中dickkopf蛋白家族表达的调控作用,使用了Biovision公司的抗DKK2抗体来检测DKK2蛋白。 更多
DVL1
dishevelled segment polarity protein 1
总数:2
Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. 2009 至该文献
使用Santa Cruz生物公司的抗Dvl抗体进行免疫组织化学实验来研究骨形态发生蛋白2在引起肺血管发生中的作用和机制。 更多
DVL2
dishevelled segment polarity protein 2
总数:4
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. 2007 至该文献
Santa Cruz Biotechnology的Dvl2抗体被用于蛋白质印迹实验,来证明在神经细胞中CK1是Wnt-5a-Dvl通路的附加成份。 更多
DVL3
dishevelled segment polarity protein 3
总数:3
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. 2007 至该文献
Santa Cruz Biotechnology的Dvl3抗体被用于蛋白质印迹实验,来证明在神经细胞中CK1是Wnt-5a-Dvl通路的附加成份。 更多
FRAT1
FRAT regulator of WNT signaling pathway 1
FRAT2
FRAT regulator of WNT signaling pathway 2
GNB5
G protein subunit beta 5
总数:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 至该文献
GSK3beta
glycogen synthase kinase 3 beta
总数:79
GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. 2012 至该文献
为了研究GSK3-TIP60-ULK1信号通路在自噬中的作用,Santa Cruz Biotechnology的抗GSK3 beta抗体被用于蛋白质印迹实验。 更多
GW182
trinucleotide repeat containing adaptor 6A
总数:3
Microtubule-dependent association of AKAP350A and CCAR1 with RNA stress granules. 2009 至该文献
为证明RNA压力颗粒与AKAP350A和CCAR1的结核是微管依赖性的,采用了Santa Cruz公司的羊抗GW182抗体进行免疫荧光试验。 更多
H2AZ1
H2A.Z variant histone 1
总数:1
Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin. 2007 至该文献
H2A组蛋白家族成员X (H2AX)
H2A.X variant histone
总数:62
The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins. 2014 至该文献
为了研究 RSFI在DNA 双链断裂修复过程中需要 RSF1分子,采用 Millipore 公司的 Gamma-H2AX 抗体进行Western Blot实验。 更多
H3
H3 clustered histone 14
总数:32
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. 2012 至该文献
为了分析在人类特异的脑前额神经中转录起始位点的组蛋白甲基化修饰,采用了Upstate的抗组蛋白H3K4抗体,进行RNA免疫沉淀实验。 更多
H3-3B
H3.3 histone B
总数:5
Hsp90alpha recruited by Sp1 is important for transcription of 12(S)-lipoxygenase in A431 cells. 2005 至该文献
H4
H4 clustered histone 14
总数:11
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 至该文献
为了研究H3K9Ac和 H3K56Ac在调控人类细胞对DNA损伤反应中的作用,采用Active Motif公司的抗H4K12Ac抗体产品1:1,000,进行了免疫印迹实验。 更多
HDAC1
histone deacetylase 1
总数:54
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 至该文献
为了说明IRF5同HATs和HDACs一起调控促炎细胞因子的转录水平表达,使用了Upstate Biotechnology公司的抗HDAC1抗体进行蛋白印迹实验。 更多
H2BC1
H2B clustered histone 1
总数:1
Testis/sperm-specific histone 2B in the sperm of donors and subfertile patients: variability and relation to chromatin packaging. 2007 至该文献
为了评估TSH2B与染色质紧密状态的关系,采用了Chemicon International公司的TSH2B抗体进行蛋白质印迹分析。
H2BC5
H2B clustered histone 5
总数:1
p53 chromatin epigenetic domain organization and p53 transcription. 2009 至该文献
为了说明染色质结构域II折叠产生的物理障碍可以造成RNA聚合酶II的消耗,使用了Abcam公司的抗组蛋白H2B抗体来进行免疫沉淀实验。
H3C6
H3 clustered histone 6
总数:5
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 至该文献
为了研究AMP激活的蛋白激酶调节细胞对代谢压力的反应的机制,使用了Abcam公司的抗组蛋白H3,抗组蛋白H3 K9Me以及抗组蛋白H3 S10ph抗体来进行免疫印迹分析。 更多
H2AC20
H2A clustered histone 20
总数:6
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. 2009 至该文献
为了研究H3K9Ac和 H3K56Ac在调控人类细胞对DNA损伤反应中的作用,采用Abcam公司的抗H2A抗体产品1:1,000,进行了免疫印迹实验。 更多
H2BC21
H2B clustered histone 21
总数:10
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. 2010 至该文献
为了研究AMP激活的蛋白激酶调节细胞对代谢压力的反应的机制,使用了Upstate Biotechnologies公司的抗组蛋白H2B抗体来进行免疫印迹分析。 更多
H3-4
H3.4 histone
总数:17
Transforming fusions of FGFR and TACC genes in human glioblastoma. 2012 至该文献
为了研究某些GBM病人有FGFR-TACC融合突变,采用了Millipore的兔抗pHH3抗体以1:500浓度进行免疫组化和免疫细胞化学实验。 更多
ICAT
catenin beta interacting protein 1
总数:12
A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta. 2013 至该文献
为了研究Gcm1和Fzd5在调控滋养层细胞分化和绒毛膜分支位点的作用,采用了Millipore抗active-beta-catenin抗体进行了免疫组化实验。 更多
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
总数:5
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 至该文献
为了研究在Purkinje神经元细胞膜钙ATP酶2缺失的小脑的分子变化,采用了Calbiochem公司的IP3R1抗体进行蛋白质印迹杂家和免疫组织化学分析。 更多
ITPR2
inositol 1,4,5-trisphosphate receptor type 2
总数:2
Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression. 2005 至该文献
KREMEN1
kringle containing transmembrane protein 1
KREMEN2
kringle containing transmembrane protein 2
总数:1
Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer. 2008 至该文献
为了考察Dickkopfs (Dkks)和Kremen2 (Krm2)在胃肠道癌症中表达的变化及,使用了ABGENT公司的抗Krm的兔抗人抗体进行了免疫组化实验。
LEF1
lymphoid enhancer binding factor 1
总数:5
Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression. 2009 至该文献
为了研究AEG1在调节肝癌发病机制中的功能,使用了Cell Signaling Technology公司的兔抗LEF1多克隆抗体来进行免疫印迹分析和免疫荧光试验。 更多
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component
LGR4
leucine rich repeat containing G protein-coupled receptor 4
LGR6
leucine rich repeat containing G protein-coupled receptor 6
LRP5
LDL receptor related protein 5
总数:2
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation. 2009 至该文献
为了表明N-钙粘素-轴蛋白-LRP5的反应对Wnt/β-钙粘素信号,成骨蛋白功能及骨形成有负调控作用,使用了Cell Signaling公司的抗-LRP5抗体进行免疫印迹实验。 更多
LRP6
LDL receptor related protein 6
总数:6
Blocking the Wnt pathway, a unifying mechanism for an angiogenic inhibitor in the serine proteinase inhibitor family. 2010 至该文献
为了研究一种丝氨酸蛋白酶抑制家族的血管生成抑制剂通过抑制Wnt通路的机制,采用Santa Cruz 公司的抗LRP6抗体,进行western blot实验。 更多
多发性内分泌腺瘤综合征1型 (MEN1)
menin 1
总数:2
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 至该文献
为了阐明c-Myb在MLL相关白血病中的作用,实验使用了Bethyl Laboratories公司的抗menin抗体进行免疫共沉淀。 更多
MOV10
Mov10 RISC complex RNA helicase
总数:2
Perturbation of the P-body component Mov10 inhibits HIV-1 infectivity. 2010 至该文献
为了研究Mov10的过表达是否可以抑制HIV-1病毒的侵染,采用了Proteintech Group的抗Mov10抗体进行蛋白质印迹实验。 更多
NEDL1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
NFATC1
nuclear factor of activated T cells 1
总数:4
Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts. 2007 至该文献
为了研究Alk3在小鼠胚胎心脏房室垫形态建成上的角色,采用了BD Biosciences公司的NFATc1抗体进行免疫组织化学分析 更多
p300
E1A binding protein p300
总数:52
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. 2011 至该文献
为了研究p300调控的AML1-ETO融合蛋白乙酰化对白血病发生至关重要,采用Santa Cruz的抗p300抗体进行蛋白印迹和ChIP实验。 更多
PA200
proteasome activator subunit 4
总数:1
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体调节蛋白PA200抗体,进行了蛋白质印迹实验.
PDE6A
phosphodiesterase 6A
总数:3
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 至该文献
为了研究磷酸二酯酶6个亚基在特发性肺纤维化中的作用使用了Abcam公司的抗PDE6A抗体(1:200稀释)来进行免疫组化实验。 更多
PDE6B
phosphodiesterase 6B
总数:2
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 至该文献
为了研究磷酸二酯酶6个亚基在特发性肺纤维化中的作用使用了FabGennix的抗PDE6B免疫印记实验。 更多
PDE6G
phosphodiesterase 6G
总数:2
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 至该文献
为了研究磷酸二酯酶6个亚基在特发性肺纤维化中的作用使用了Santa Cruz Biotechnology 的抗PDE6G免疫印记实验。 更多
PFN1
profilin 1
总数:4
Self-assembly of filopodia-like structures on supported lipid bilayers. 2010 至该文献
为了研究丝状伪足样结构是如何自组装的,使用了Axxora公司的抗profilin抗体来进行免疫荧光实验。 更多
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
总数:1
Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl. 2009 至该文献
为了研究wnt3a和dvl对磷脂酰肌醇激酶的调控作用,采用了Abgent的抗PIP5KIβ抗体进行免疫印迹实验。
PKC甲 (PKC alpha)
protein kinase C alpha
总数:50
A male with unilateral microphthalmia reveals a role for TMX3 in eye development. 2010 至该文献
为了研究TMX3基因在眼发育中的功能,采用了Santa Cruz Biotechnology公司的兔抗PKCAα抗体,进行了蛋白质印迹实验. 更多
PKC乙 (PKC beta)
protein kinase C beta
总数:27
Protein kinase C in porcine retinal arteries and neuroretina following retinal ischemia-reperfusion. 2009 至该文献
为了研究PKC在调控视猪网膜缺血再灌注过程中的作用,采用了Santa Cruz Biotechnology公司的鼠单克隆抗beta-actin抗体产品(1:5000),进行了免疫印迹实验 更多
PLCB2
phospholipase C beta 2
总数:3
Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx. 2005 至该文献
PP2AC
protein phosphatase 2 catalytic subunit alpha
总数:20
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 至该文献
PPP2R1A
protein phosphatase 2 scaffold subunit Aalpha
总数:7
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. 2008 至该文献
PPP2R1B
protein phosphatase 2 scaffold subunit Abeta
总数:2
SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process. 2007 至该文献
为了研究sk1的功能,采用了Sigma-Aldrich公司的单克隆抗PP2A抗体,进行了蛋白印记实验。 更多
PPP3CA
protein phosphatase 3 catalytic subunit alpha
总数:4
Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis. 2009 至该文献
为了推断钙调磷酸酶活性和白血病细胞凋亡能够通过糖皮质激素介导上调的RCAN1-1来调节,使用了Sigma-Aldrich公司的抗体calcineurin A来进行免疫印迹分析。 更多
PPP3CB
protein phosphatase 3 catalytic subunit beta
总数:2
Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models. 2005 至该文献
Chemicon的兔抗磷酸酶抗体被用于免疫组化实验,来研究触发星形胶质细胞活性的机制。 更多
PPP3R1
protein phosphatase 3 regulatory subunit B, alpha
总数:3
Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. 2006 至该文献
为了研究ASK1和控制心肌病死亡和生长的钙调磷蛋白磷酸酶-NFAT之间的直接相互作用和可逆调节,采用了Sigma公司的CnB1抗体进行了蛋白质印迹分析 更多
PRKCG
protein kinase C gamma
总数:12
The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. 2007 至该文献
PRKG1
protein kinase cGMP-dependent 1
总数:7
Hsp90/Hsp70 chaperone machine regulation of the Saccharomyces MAL-activator as determined in vivo using noninducible and constitutive mutant alleles. 2008 至该文献
PSMA1
proteasome 20S subunit alpha 1
总数:9
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 至该文献
PSMA3
proteasome 20S subunit alpha 3
总数:3
Two histone marks establish the inner centromere and chromosome bi-orientation. 2010 至该文献
为了研究内着丝粒是如何建立的和CPC复合物是如何靶向到此位点的机制,使用了Santa Cruz Biotechnology公司的抗Psc3抗体来进行染色质免疫沉淀实验。 更多
PSMA4
proteasome 20S subunit alpha 4
总数:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献
为了研究免疫蛋白酶体在多发性硬化发病机制的作用,采用Affinity-Biomol International小鼠抗人的20S proteasome subunit alpha4单克隆抗体进行免疫组织化学试验。 更多
PSMA7
proteasome 20S subunit alpha 7
总数:4
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 至该文献
为了在内质网相关蛋白的降解途径(ERAD)中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能,使用了Enzo Life Sciences公司的抗体alpha7来进行免疫印迹分析。 更多
PSMB1
proteasome 20S subunit beta 1
总数:2
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体亚基β1抗体,进行了蛋白质印迹实验. 更多
PSMB5
proteasome 20S subunit beta 5
总数:1
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体亚基β5抗体,进行了蛋白质印迹实验.
PSMB8
proteasome 20S subunit beta 8
总数:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献
为了研究免疫蛋白酶体在多发性硬化发病机制的作用,采用Affinity-Biomol International抗LMP7抗体进行免疫组织化学试验。 更多
PSMB9
proteasome 20S subunit beta 9
总数:2
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献
为了研究免疫蛋白酶体在多发性硬化发病机制的作用,采用Affinity-Biomol International抗LMP2抗体进行免疫组织化学试验。 更多
PSMC4
proteasome 26S subunit, ATPase 4
总数:8
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. 2010 至该文献
为了研究在帕金森疾病模型中雷怕霉素对神经元的保护作用,采用了Cell Signaling Technology的抗phospho-Ser235/236-S6抗体进行免疫细胞化学试验。 更多
PSMC6
proteasome 26S subunit, ATPase 6
总数:1
Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 至该文献
PSMD2
proteasome 26S subunit, non-ATPase 2
总数:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 至该文献
为了说明hHR23A介导的Vpr与蛋白酶体的互作在病毒复制过程中有重要作用,使用了Calbiochem公司的19S蛋白酶体S2亚基的兔多抗来进行免疫印记实验。
PSMD4
proteasome 26S subunit, non-ATPase 4
总数:3
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 至该文献
为了说明hHR23A介导的Vpr与蛋白酶体的互作在病毒复制过程中有重要作用,使用了Calbiochem公司的19S蛋白酶体S5a亚基的兔多抗来进行免疫印记实验。 更多
PSMD9
proteasome 26S subunit, non-ATPase 9
总数:13
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 至该文献
为了研究在管腔乳腺癌中雌激素敏感性以及抗雌激素抗性的获得,采用了Santa Cruz 的抗p27抗体进行了western blot实验。 更多
PSME1
proteasome activator subunit 1
总数:3
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. 2010 至该文献
为了研究免疫蛋白酶体在多发性硬化中的作用,采用Affinity-Biomol International兔抗PA28alpha多克隆抗体进行免疫组织化学试验。 更多
PSME2
proteasome activator subunit 2
总数:1
Chronic ethanol feeding affects proteasome-interacting proteins. 2009 至该文献
为了确认长期酒精喂养对蛋白酶体相互作用蛋白表达的影响,采用了BIOMOL公司的抗PA28β抗体进行免疫印迹法实验。
Ras相关C3肉毒杆菌毒素底物1 (Rac1)
Rac family small GTPase 1
总数:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 至该文献
为研究RhoGDI2通过Rho GTPases抑制代谢的作用,采用了Millipore公司的抗Rac1单克隆抗体(1:1,000)进行免疫印迹试验。 更多
RAC2
Rac family small GTPase 2
总数:3
In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression. 2009 至该文献
为了研究ROR2在淋巴瘤侵润性的作用,采用Proteintech公司的Rac2抗体,进行了蛋白印记实验。 更多
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit
总数:4
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination. 2010 至该文献
为了研究PTIP促进特异性的染色质改变和免疫球蛋白类别转换重组的机制,使用了Bethyl公司的抗RBBP5抗体来进行染色质免疫沉淀实验。 更多
RBX1
ring-box 1
总数:5
Poxvirus ankyrin repeat proteins are a unique class of F-box proteins that associate with cellular SCF1 ubiquitin ligase complexes. 2008 至该文献
RhoA
ras homolog family member A
总数:49
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 至该文献
为了研究沉默RhoA和RhoC的表达对人类结直肠癌体内生长的影响,采用Santa Cruz公司的抗RhoA抗体进行了免疫组织化学实验。 更多
ROR1
receptor tyrosine kinase like orphan receptor 1
ROR2
receptor tyrosine kinase like orphan receptor 2
总数:2
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 至该文献
为了研究ROR2调节转移性黑色素瘤的Wnt5A,采用Cell Signaling公司的ROR2抗体,进行了细胞免疫荧光实验。 更多
RPS27A
ribosomal protein S27a
总数:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 至该文献
为了在内质网相关蛋白的降解途径(ERAD)中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能,使用了Santa Cruz Biotechnology公司的抗体ubiquitin来进行免疫印迹分析。 更多
RUVBL1
RuvB like AAA ATPase 1
总数:2
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization. 2008 至该文献
为了研究ILK在调控有丝分裂纺锤体组装中的作用,采用Proteintech公司的兔抗RUVBL1抗体产品,进行了免疫印迹实验。 更多
SCRIB
scribble planar cell polarity protein
总数:2
Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development. 2009 至该文献
为了阐述Hippo信号通路是斑马鱼正常的前肾发育所必须的,并且Scribble参与该通路,采用了Santa Cruz公司的兔多克隆和山羊多克隆抗Scribble抗血清(1:500),进行了免疫沉淀实验。 更多
SFRP1
secreted frizzled related protein 1
总数:2
Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma. 2007 至该文献
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
总数:3
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 至该文献
为了研究Smurf2在促进乳腺癌转移中的功能,使用了Santa Cruz Biotechnology公司的抗Smurf1抗体来进行免疫印迹分析和免疫组化实验。 更多
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
总数:3
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 至该文献
为了研究Smurf2在促进乳腺癌转移中的功能,使用了Santa Cruz Biotechnology公司的抗Smurf2抗体来进行免疫印迹分析和免疫组化实验。 更多
Tak1
mitogen-activated protein kinase kinase kinase 7
总数:10
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 至该文献
为了研究NRAGE在调节NF-kappaB活性时所发挥的作用,采用了Santa Cruz的小鼠抗Tak1抗体进行蛋白质印迹试验。 更多
TCF7L1
transcription factor 7 like 1
总数:2
Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen. 2008 至该文献
为了证明Erα与β-catenin/Lef-1/Tcf-3信号的整合,是子宫中雌激素依赖的内源基因调控的必要过程,采用了Santa Cruz Biotechnology的经亲和纯化的Tcf-3抗体,进行免疫沉淀反应和蛋白质印迹 更多
TCF7L2
transcription factor 7 like 2
总数:6
Growth inhibition of human colon cancer cell line HCT116 by bis[2-(acylamino)phenyl] disulfide and its action mechanism. 2008 至该文献
为了研究bis[2-(acylamino)phenyl] disulfide诱导的生长抑制的作用机制,采用了Upstate Biotechnology公司的TCF-4抗体进行免疫共沉淀实验及蛋白免疫印迹实验。 更多
端粒末端转移酶逆转录酶 (TERT)
telomerase reverse transcriptase
总数:10
The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model. 2010 至该文献
为了研究磷酸化的Akt对后囊的作用采用了Calbiochem公司的抗TERT抗体(1:350稀释)来进行免疫组化实验。 更多
Tip60
lysine acetyltransferase 5
总数:14
PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis. 2009 至该文献
为了说明PDCD5能维持Tip60蛋白的组蛋白乙酰转移酶活性和作为一个Tip60的共激活物促进DNA损伤诱导的细胞凋亡,使用了Santa Cruz Biotechnology公司的抗Tip60抗体进行蛋白印记实验。 更多
TLE1
TLE family member 1, transcriptional corepressor
总数:1
Esg1, expressed exclusively in preimplantation embryos, germline, and embryonic stem cells, is a putative RNA-binding protein with broad RNA targets. 2006 至该文献
TLE2
TLE family member 2, transcriptional corepressor
TLE3
TLE family member 3, transcriptional corepressor
TLE4
TLE family member 4, transcriptional corepressor
TNKS2
tankyrase 2
总数:1
Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins. 2009 至该文献
为了在蛋白质组范围内发现转录因子HIF的新的底物,使用了Abcam公司的抗Tankyrase抗体来进行免疫印迹分析和免疫沉淀实验。
TNRC6B
trinucleotide repeat containing adaptor 6B
TRRAP
transformation/transcription domain associated protein
总数:3
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. 2009 至该文献
为研究STAGA亚单位ADA2b在调节人GCN5催化作用中所扮演的角色,将Santa Cruz提供的抗TRRAP抗体用于蛋白免疫印迹实验中。 更多
UBC
ubiquitin C
总数:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 至该文献
为了研究突触的可塑性,采用了Enzo Life Sciences的抗Ubiquitin的抗体进行了免疫印迹实验。 更多
泛肽 (ubiquitin)
ubiquitin B
总数:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 至该文献
为了阐明BCL6和HB-EGF-CTF相互作用,并且这种相互作用可能会引起细胞周期蛋白D2在人胃癌细胞中表达,采用了Cell Signaling Technology公司的小鼠抗泛素单克隆抗体,进行了蛋白质印迹实验。 更多
VPS26A
VPS26, retromer complex component A
总数:1
Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. 2007 至该文献
VPS29
VPS29 retromer complex component
总数:1
Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. 2007 至该文献
VPS35
VPS35 retromer complex component
总数:1
Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. 2007 至该文献
WNT1
Wnt family member 1
总数:4
WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. 2009 至该文献
为了研究WISP1在调控ATTⅡ细胞超常增生及可塑性中的作用,使用了Abcam公司的抗WNT1抗体,进行了免疫印迹和组织化学实验。 更多
WNT10B
Wnt family member 10B
总数:1
NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation. 2010 至该文献
为了研究NF-E2在调控ROS累积和巨核细胞成熟中的作用,采用了Santa Cruz Biotechnology公司的抗CD61抗体产品,进行了免疫沉淀实验。
WNT3A
Wnt family member 3A
总数:1
Functional Wnt signaling is increased in idiopathic pulmonary fibrosis. 2008 至该文献
WNT4
Wnt family member 4
总数:2
Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen. 2008 至该文献
为了证明Erα与β-catenin/Lef-1/Tcf-3信号的整合,是子宫中雌激素依赖的内源基因调控的必要过程,采用了Santa Cruz Biotechnology的经亲和纯化的Wnt-4抗体,进行蛋白质印迹实验 更多
WNT5A
Wnt family member 5A
总数:4
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 至该文献
为了研究Wnt5A对ROR2的影响,采用BD公司的Wnt5A抗体,进行了蛋白印记实验。 更多
WNT7A
Wnt family member 7A
总数:1
The p53 transcriptional target gene wnt7b contributes to NGF-inducible neurite outgrowth in neuronal PC12 cells. 2008 至该文献
Santa Cruz 公司生产的wnt7a抗体可用于免疫印迹实验,来研究转录因子P53如何调控经神经生长因子NGF处理的PC12细胞中二乙基溴乙酰胺的分化。
WNT7B
Wnt family member 7B
总数:1
The p53 transcriptional target gene wnt7b contributes to NGF-inducible neurite outgrowth in neuronal PC12 cells. 2008 至该文献
Santa Cruz 公司生产的wnt7b抗体可用于免疫印迹实验,来研究转录因子P53如何调控经神经生长因子NGF处理的PC12细胞中二乙基溴乙酰胺的分化。
WTX
APC membrane recruitment protein 1
XIAP
X-linked inhibitor of apoptosis
总数:28
Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance. 2009 至该文献
为研究PARP-1在电离辐射诱导的NF-κB信号级联放大过程中所起的作用,将R&D systems提供的抗XIAP抗体用于蛋白免疫印迹实验中。 更多
XPO1
exportin 1
总数:7
Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis. 2009 至该文献
为了研究LKB1在核浆转运过程中的作用,采用了Santa Cruz Biotechnology公司的CRM-1抗体进行蛋白印迹实验。 更多