Thrombin signalling through proteinase activated receptors (PARs)
基因
试剂
文献样例
产品评述样例
ARRB1
arrestin beta 1
总数:7
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 至该文献
为了说明arrestin-2/STAM-1复合体通过泛素化HRS调节CXCR4溶酶体分选,使用了Santa Cruz Biotechnology公司的beta-arrestin1/2兔多抗(21-B1)来进行免疫印记实验。 更多
ARRB2
arrestin beta 2
总数:3
Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation. 2006 至该文献
ERK1
mitogen-activated protein kinase 3
总数:252
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 2009 至该文献
为研究BAD蛋白磷酸化在β-Arrestin-2介导的抗凋亡反应中的调控作用,采用了密理博公司的抗ERK1/2多克隆抗体进行免疫印迹和免疫沉淀试验。 更多
ERK2
mitogen-activated protein kinase 1
总数:490
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 2010 至该文献
为了研究在气喘患者中由TGFbeta和IL-10抑制造成的对T细胞的抗性的信号传导机制,采用了Santa Cruze Biotechnology的抗ERK1/2抗体和抗磷酸化ERK1/2抗体进行了免疫印迹检测,免疫组化实验和流式细胞检测。 更多
F2RL2
coagulation factor II thrombin receptor like 2
总数:2
Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. 2005 至该文献
Upstate Biotechnologies的Par-3抗体被用于蛋白质印迹和免疫细胞化学实验,来研究Par-3在哺乳动物上皮细胞极化过程中的作用。 更多
Galpha13
G protein subunit alpha 13
总数:7
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 至该文献
为了研究切割的NIK 导致非经典的NF- kB 活性,采用了Abcam的抗BAFF抗体进行免疫印迹试验。 更多
GNA12
G protein subunit alpha 12
总数:6
G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function. 2005 至该文献
GNAQ
G protein subunit alpha q
总数:11
Caveolin-1 alters Ca(2+) signal duration through specific interaction with the G alpha q family of G proteins. 2008 至该文献
使用Santa Cruz 生物公司的抗Gαq抗体进行免疫组化实验来研究caveolin-1 和G蛋白家族Gαq 在钙信号持续过程中的相互作用效果。 更多
GNB5
G protein subunit beta 5
总数:1
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. 2007 至该文献
PAR-1 (PAR-1)
coagulation factor II thrombin receptor
总数:7
Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder. 2007 至该文献
Src
SRC proto-oncogene, non-receptor tyrosine kinase
总数:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 至该文献
为了研究在管腔乳腺癌中雌激素敏感性以及抗雌激素抗性的获得,采用了Calbiochem的抗SRC抗体进行了western blot实验。 更多