酗酒
基因
试剂
文献样例
产品评述样例
ALDH2
aldehyde dehydrogenase 2 family (mitochondrial)
总数:1
A pilot study on subacute ethanol treatment of ALDH2 KO mice. 2007 至该文献
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
总数:2
GABA(A) receptor downregulation in brains of subjects with autism. 2009 至该文献
Alpha Diagnostic International GABRA2抗体用于免疫印迹来证明GABAA受体在孤独症患者大脑中表达量的下降 更多
DRD2
dopamine receptor D2
总数:6
D1 and D2 dopamine receptor expression is regulated by direct interaction with the chaperone protein calnexin. 2007 至该文献
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
serotonin transporter
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
总数:7
The existence of a local 5-hydroxytryptaminergic system in peripheral arteries. 2008 至该文献
为了检测具有生理机能的5羟色胺能系统是否存在于外周动脉,采用了Santa Cruz Biotechnology的抗SERT-C20抗体,进行免疫组化和蛋白质印迹实验 更多
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
ANKK1
ankyrin repeat and kinase domain containing 1
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
mu opioid receptor
opioid receptor, mu 1
总数:10
Endomorphin-2 is released from newborn rat primary sensory neurons in a frequency- and calcium-dependent manner. 2008 至该文献
为了检测鼠原代感觉神经元细胞表达的功能依赖性释放因子END-2,采用Novus Biologicals公司的兔抗MOR抗体,进行免疫细胞化学实验。 更多
MAOA
monoamine oxidase A
总数:1
The existence of a local 5-hydroxytryptaminergic system in peripheral arteries. 2008 至该文献
为了检测具有生理机能的5羟色胺能系统是否存在于外周动脉,采用了Santa Cruz Biotechnology的兔MAO A基因的多抗(H-70,可以识别人类MAO A的458-527号氨基酸),进行免疫组化和蛋白质印迹实验
TPH1
tryptophan hydroxylase 1
总数:3
The existence of a local 5-hydroxytryptaminergic system in peripheral arteries. 2008 至该文献
为了检测具有生理机能的5羟色胺能系统是否存在于外周动脉,采用了Sigma的抗TPH单抗(WH-3,可被TPH1和TPH2识别),进行免疫组化和蛋白质印迹实验 更多
CRHR1
corticotropin releasing hormone receptor 1
总数:9
Corticotropin-releasing factor 2 receptor localization in skeletal muscle. 2004 至该文献
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
NR2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
总数:17
Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers. 2009 至该文献
为验证以下假说,即:胰岛素信号提供了对抗Aβ衍生的可扩散性突触毒性的生理防御机制,将Santa Cruz提供的抗N-甲基-D-天门冬氨酸受体NR1亚单位抗体用于细胞免疫化学实验中。 更多
GRIK1
glutamate receptor, ionotropic, kainate 1
总数:4
Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors. 2007 至该文献
为研究Homer 1a在神经元功能中的作用,采用Chemicon公司兔源性代谢性谷氨酸受体5(mGluR5)多克隆抗体用于免疫细胞化学实验。 更多
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
ADH5
alcohol dehydrogenase 5 (class III), chi polypeptide
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6
总数:1
N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma. 2009 至该文献
为了研究N-myc在促进肿瘤形成过程中所起的作用,使用了Chemicon公司的抗Gabra6抗体来进行免疫组化分析。
DAT
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
总数:10
Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease. 2009 至该文献
运用Santa Cruz公司的抗多巴胺转运体(DAT)抗体,进行免疫印迹实验以研究RPE细胞移植在治疗帕金森病中的治疗效果。 更多
OPRL1
opiate receptor-like 1
总数:1
Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia. 2008 至该文献
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
总数:7
Dendritic A-type potassium channel subunit expression in CA1 hippocampal interneurons. 2008 至该文献
为了研究在缺少鞘脂激活蛋白原的小鼠中,CEBPD对大脑疾病的影响,采用了Sigma的鼠抗GABA多抗(A2052),进行免疫组化实验 更多
OPRK1
opioid receptor, kappa 1
总数:1
The adaptor Grb7 links netrin-1 signaling to regulation of mRNA translation. 2007 至该文献
为了鉴定Grb7是新的RNA结合蛋白起着分子接合体传送Netrin-1信号的作用,使用了Santa Cruz Biotechnology公司的抗KOR抗体,进行了免疫印迹实验。
DRD1
dopamine receptor D1
总数:2
Dopamine D1 and D2 receptor Co-activation generates a novel phospholipase C-mediated calcium signal. 2004 至该文献
CHRNA5
cholinergic receptor, nicotinic, alpha 5
总数:2
Mecamylamine suppresses Basal and nicotine-stimulated choroidal neovascularization. 2008 至该文献
为了研究在脉络膜新生血管病理中nAChR的作用,采用了Santa Cruz Biotechnology的nAChRα5抗体,进行蛋白质印迹实验 更多
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A
总数:4
Chronic treatment with a serotonin(2) receptor (5-HT(2)R) agonist modulates the behavioral and cellular response to (+)-3,4-methylenedioxymethamphetamine [(+)-MDMA]. 2006 至该文献
ACTH
proopiomelanocortin
总数:14
SUMOylation inhibits SF-1 activity by reducing CDK7-mediated serine 203 phosphorylation. 2009 至该文献
使用Calbiochem人促肾上腺皮质激素孵育细胞,来证明SUMO化在减少CDK7引起的SF-1磷酸化中发挥作用。 更多
CHRM2
cholinergic receptor, muscarinic 2
总数:7
Kaposi's sarcoma-associated herpesvirus ORF45 interacts with kinesin-2 transporting viral capsid-tegument complexes along microtubules. 2009 至该文献
为了说明KSHV被膜蛋白在病毒质粒的细胞转运过程中的重要作用,采用了Sigma的鼠单抗Flag M2抗体进行免疫沉淀。 更多
CNR1
cannabinoid receptor 1 (brain)
总数:3
CB2 cannabinoid receptor agonists attenuate TNF-alpha-induced human vascular smooth muscle cell proliferation and migration. 2008 至该文献
Cyp2e1
cytochrome P450, family 2, subfamily E, polypeptide 1
总数:10
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 至该文献
使用牛津大学生物医学研究的抗CYP2E1(1:1000) 抗体进行免疫印迹实验来研究心肌CPR和CPR依赖酶在阿霉素介导的急性心脏毒性中的作用。 更多
CHRNA4
cholinergic receptor, nicotinic, alpha 4
总数:5
Roles for nicotinic acetylcholine receptor subunit large cytoplasmic loop sequences in receptor expression and function. 2005 至该文献
为了检测在人SH-EP1 细胞中的受体蛋白nAChR,采用了Sigma-Aldrich公司的mAb 299(靶标N端胞外区域的鼠抗nAChRα4亚基)进行蛋白质印迹分析。 更多
CHRNA3
cholinergic receptor, nicotinic, alpha 3
总数:3
Ubiquilin-1 regulates nicotine-induced up-regulation of neuronal nicotinic acetylcholine receptors. 2005 至该文献
α突触核蛋白 (alpha synuclein)
synuclein, alpha (non A4 component of amyloid precursor)
总数:27
Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases. 2008 至该文献
为了研究多种神经退化疾病中TDP-43在纤维神经包含物中的作用,使用了Zymed公司的单克隆泛素抗体进行免疫组化实验。 更多
BDNF
brain-derived neurotrophic factor
总数:20
NGF and BDNF signaling control amyloidogenic route and Abeta production in hippocampal neurons. 2008 至该文献
为了研究神经生长因子和脑源性神经营养因子在神经元的凋亡性死亡中的作用,采用Novus公司的单克隆抗BDNF抗体(30 μg/ml),进行细胞培养实验。 更多
PKC epsilon
protein kinase C, epsilon
总数:26
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. 2009 至该文献
为了研究在肠部PKCα抑制肿瘤的机制,采用了Santa Cruz Biotechnology公司的抗PKCε抗体,进行了蛋白质印迹实验。 更多
HSPA1B
heat shock 70kDa protein 1B
总数:39
A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease. 2009 至该文献
为了阐明在帕金森症中,一个新的转铁蛋白/TfR2-介导的线粒体铁离子运输体系被阻断这样一个机制,采用了Stressgen公司的抗Hsp70抗体应用于免疫组化实验中。 更多
CREB
cAMP responsive element binding protein 1
总数:64
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 至该文献
为了说明在人NT2细胞中血管活性肠肽可以促进HCMV MIE的表达,使用了Epitomics公司的兔单克隆抗CREB抗体来进行蛋白印迹实验。 更多
神经肽Y (neuropeptide Y)
总数:7
Bretylium abolishes neurotransmitter release without necessarily abolishing the nerve terminal action potential in sympathetic terminals. 2008 至该文献
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
总数:1
Regulation of human methylenetetrahydrofolate reductase by phosphorylation. 2005 至该文献
ApoE基因 (ApoE)
apolipoprotein E
总数:18
ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE. 2004 至该文献
为了证明正常中枢神经系统的载脂蛋白E表达和星形胶质细胞分泌的载脂蛋白E脂化需要ABCA1,在酶联免疫吸附试验中使用了Calbiochem的生物素化的山羊抗apoE抗体。 更多
TNF-alpha
tumor necrosis factor
总数:151
TNF-alpha Regulates the Effects of Irradiation in the Mouse Bone Marrow Microenvironment. 2010 至该文献
为了研究TNF-a在射线诱导的骨髓细胞凋亡和骨髓功能障碍中的功能,使用了BD R&D Systems公司的抗鼠TNF-a抗体来阻断细胞的TNF-a通路的激活。 更多
p50
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
总数:106
Vaccinia virus E3 suppresses expression of diverse cytokines through inhibition of the PKR, NF-kappaB, and IRF3 pathways. 2009 至该文献
为了研究痘苗病毒双链RNA结合蛋白E3抑制细胞因子表达的机制,使用了Epitomics公司的抗NF-kB p50抗体来进行免疫印记分析。 更多