肌萎缩性侧索硬化症
基因
试剂
文献样例
产品评述样例
Cu Zn superoxide dismutase
superoxide dismutase 1, soluble
总数:16
Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3. 2009 至该文献
为证实突变的SOD1可以通过隔离KAP3来降低轴突的胆碱乙酰转移酶运输量和乙酰胆碱的释放量，使用了Calbiochem公司的抗SOD1抗体来进行蛋白印迹分析。 更多
TDP 43
TAR DNA binding protein
总数:37
Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps. 2010 至该文献
为介绍一种可以实现靶基因定点插入和条件性表达的重组酶介导的盒式交换(RMCE)系统，采用了ABCAM的抗人TARDBP抗体(ab57105,1.25 mg/ml)进行了western免疫印迹实验。 更多
FUS
fused in sarcoma
总数:6
A Yeast Model of FUS/TLS-Dependent Cytotoxicity.. 2011 至该文献
为了研究酵母中FUS/TLS依赖的细胞毒性，采用了Abcamn公司的抗FUS抗体(1:1000)进行了免疫印记实验。 更多
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
DPP6
dipeptidyl-peptidase 6
总数:2
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons. 2006 至该文献
C9orf72
chromosome 9 open reading frame 72
FGGY
FGGY carbohydrate kinase domain containing
KIFAP3
kinesin-associated protein 3
总数:3
Mobility of the von Hippel-Lindau tumour suppressor protein is regulated by kinesin-2. 2008 至该文献
ANG
angiogenin, ribonuclease, RNase A family, 5
总数:1
Angiogenin distribution in human term placenta, and expression by cultured trophoblastic cells. 2003 至该文献
chromogranin B
chromogranin B (secretogranin 1)
总数:1
Localization of the secretory granule marker protein chromogranin B in the nucleus. Potential role in transcription control. 2002 至该文献
peripherin
总数:3
Homeodomain transcription factor Phox2a, via cyclic AMP-mediated activation, induces p27Kip1 transcription, coordinating neural progenitor cell cycle exit and differentiation. 2006 至该文献
为研究通过诱导p27(Kip1)转录使Prd 家族同源结构域转录因子Phox2a对应的细胞周期引出端及分化，采用Chemicon 公司生产的感光受体外周蛋白 peripherin抗体用于免疫组化实验。 更多
optineurin
总数:3
Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth.. 2011 至该文献
为了研究沙门氏菌的生长被自噬受体optineurin的磷酸化限制，采用immunGlobe的抗磷酸化OPTN抗体进行蛋白印迹和免疫细胞化学实验。 更多
SCA2
ataxin 2
CHMP2B
charged multivesicular body protein 2B
总数:1
Cortical Constriction During Abscission Involves Helices of ESCRT-III-Dependent Filaments.. 2011 至该文献
为了研究细胞连接桥上CHMP2B的定量，采用了Abcam公司兔抗CHMP2B抗体进行了组织免疫化学方面的实验。
SETX
senataxin
总数:1
Senataxin, the yeast Sen1p orthologue: characterization of a unique protein in which recessive mutations cause ataxia and dominant mutations cause motor neuron disease. 2006 至该文献
PON1
paraoxonase 1
总数:2
Oligomeric states of the detergent-solubilized human serum paraoxonase (PON1). 2002 至该文献
GRN
granulin
总数:7
Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy. 2010 至该文献
为研究progranulin的在体神经保护作用和对运动轴突病的潜在治疗能力，采用了R&D Systems公司的抗人单克隆/生物素酰化PGRN抗体进行ELISA试验。 更多
PON2
paraoxonase 2
chromogranin A
chromogranin A (parathyroid secretory protein 1)
总数:22
Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. 2008 至该文献
IGF-1
insulin-like growth factor 1 (somatomedin C)
总数:13
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 至该文献
为研究胰岛素生长因子在骨髓瘤细胞生长过程中所发挥的作用，及其受体表达与骨髓瘤患者预后的相关性，将Abcam公司提供的兔抗胰岛素样生长因子1抗体用于蛋白免疫印迹实验中。 更多
cystatin C
总数:2
Cysteine protease cathepsin F is expressed in human atherosclerotic lesions, is secreted by cultured macrophages, and modifies low density lipoprotein particles in vitro. 2004 至该文献
HFE
hemochromatosis
血管内皮生长因子 (VEGF)
vascular endothelial growth factor A
总数:76
Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib. 2008 至该文献
为了研究不间断给药伊立替康（irinotecan）对结肠直肠癌细胞的影响，采用了Oncogene Research Products公司的VEGF-A抗体进行免疫组化实验。 更多
MMP-9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
总数:44
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 至该文献
为了研究蛋白激酶D1抑制乳腺肿瘤细胞侵袭的机制，采用了Epitomics公司的抗MMP-9抗体，进行了免疫组织化学实验。 更多
ApoE基因 (ApoE)
apolipoprotein E
总数:17
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 至该文献
为了研究高效肝炎C病毒颗粒的形成条件，采用了Calbiochem公司的抗ApoE抗体进行蛋白免疫印迹实验。 更多