CHO细胞
基因
试剂
文献样例
产品评述样例
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
总数:2
Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide cross-linking of substituted cysteines. 2009 至该文献
为了定位在钾离子通道中的KCNE1和KCNQ1，采用了Santa Cruz的羊抗Q1抗体进行免疫印迹分析。 更多
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
总数:1
Interaction between Dax-1 and steroidogenic factor-1 in vivo: increased adrenal responsiveness to ACTH in the absence of Dax-1. 2002 至该文献
在免疫印迹实验中使用了Santa Cruz Biotechnology公司的ACTH受体抗体（1：100稀释）用于研究体内Dax-1和Ⅰ型类固醇生成因子（SF1）之间的相互作用。
vascular adhesion protein 1
amine oxidase, copper containing 3 (vascular adhesion protein 1)
CD41
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
总数:13
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.. 2011 至该文献
为了研究人造血系统细胞给以不同刺激的反应能通过单细胞多因子分选进行分析，采用Biolegend的抗CD41抗体以1ug/ml浓度进行细胞多因子分选实验。 更多
MRAP
melanocortin 2 receptor accessory protein
MRAP2
melanocortin 2 receptor accessory protein 2
HERG
potassium voltage-gated channel, subfamily H (eag-related), member 2
总数:6
Silencing of herg gene by shRNA inhibits SH-SY5Y cell growth in vitro and in vivo. 2008 至该文献
为了研究herg对于调节SH-SY5Y细胞生长和增殖的重要作用，采用了Santa Cruz公司的抗HERG(sc-15968,1:1000)抗体进行了免疫印记实验。 更多
整合素β3 (integrin beta3)
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
总数:28
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression. 2010 至该文献
为了研究活化状态的p42/44和p38在MMP-13表达中的作用，采用了Santa Cruz Biotechnology公司的小鼠单克隆整合素β3抗体(1:1000)，进行了蛋白质印迹实验。 更多
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
ACCN2
amiloride-sensitive cation channel 2, neuronal
总数:2
Knockdown of ASIC1 and epithelial sodium channel subunits inhibits glioblastoma whole cell current and cell migration. 2009 至该文献
为了研究ASIC1对成胶质细胞瘤迁移和全细胞电流的影响，采用了Alomone Labs的的抗ASIC1抗体进行免疫印迹实验。 更多
GULP1
GULP, engulfment adaptor PTB domain containing 1
CHRM1
cholinergic receptor, muscarinic 1
总数:3
M(1) and M(2) muscarinic acetylcholine receptor subtypes mediate Ca(2+) channel current inhibition in rat sympathetic stellate ganglion neurons. 2006 至该文献
NPC2
Niemann-Pick disease, type C2
淀粉样蛋白前体 (APP)
amyloid beta (A4) precursor protein
总数:81
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 至该文献
为了研究通过定量蛋白质组学发现新的BACE1底物，采用Chemicon的APP抗体以1:1,000稀释进行蛋白印迹实验。 更多
HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
总数:1
Calmodulin interacts with the third intracellular loop of the serotonin 5-hydroxytryptamine1A receptor at two distinct sites: putative role in receptor phosphorylation by protein kinase C. 2004 至该文献
Kv4.3
potassium voltage-gated channel, Shal-related subfamily, member 3
总数:5
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons. 2006 至该文献
丁酰胆碱酯酶 (butyrylcholinesterase)
SSTR5
somatostatin receptor 5
总数:1
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. 2008 至该文献
为研究胰腺Lkb1缺失导致的腺泡极性损失和胞囊肿瘤，采用了Zymed公司的抗somatostatin抗体进行蛋白质印迹和免疫组化试验。
NPY2R
neuropeptide Y receptor Y2
总数:1
Neuropeptide Y modulates effects of bradykinin and prostaglandin E2 on trigeminal nociceptors via activation of the Y1 and Y2 receptors. 2007 至该文献
GP9
glycoprotein IX (platelet)
总数:3
The cysteine knot of platelet glycoprotein Ib beta (GPIb beta) is critical for the interaction of GPIb beta with GPIX. 2002 至该文献
GLP1R
glucagon-like peptide 1 receptor
总数:2
Quantitative trait loci for carbohydrate and total energy intake on mouse chromosome 17: congenic strain confirmation and candidate gene analyses (Glo1, Glp1r). 2007 至该文献
F7
coagulation factor VII (serum prothrombin conversion accelerator)
总数:1
Extrahepatic synthesis of factor VII in human atherosclerotic vessels. 2003 至该文献
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
总数:1
Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons. 2006 至该文献
Chemicon的KCNQ3抗体被用于蛋白质印迹实验，来研究Kv7/KCNQ/M通道在控制细胞兴奋性中的作用。
tripeptidyl peptidase I
总数:1
Functional dissection of human and mouse POT1 proteins. 2009 至该文献
为了阐明人类和老鼠的POT1蛋白的作用机制，采用了sigma公司的hTPP1 (1151)抗体，进行蛋白质印记实验。
CD59
CD59 molecule, complement regulatory protein
总数:10
Activity after site-directed mutagenesis of CD59 on complement-mediated cytolysis. 2008 至该文献
为阐明CD59 的W40 位点对其抗补体效应具有重要作用，采用了Santa Cruz公司的羊抗人CD59多克隆抗体（Catalog #，sc-7077）进行ELISA. 更多
CDC50A
transmembrane protein 30A
XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3
总数:3
Domain mapping of the Rad51 paralog protein complexes. 2004 至该文献
PCSK9
proprotein convertase subtilisin/kexin type 9
总数:2
Antibody-mediated disruption of the interaction between PCSK9 and the low-density lipoprotein receptor. 2009 至该文献
为阐明PCSK9特异性抗体可以逆转PCSK9介导的对细胞表面LDLRs的下调作用，采用了Abcam的羊抗人PCSK9多克隆抗体（catalog #:Ab28770）进行抗体阻断实验。 更多
XPF
excision repair cross-complementing rodent repair deficiency, complementation group 4
总数:1
Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links. 2003 至该文献
为研究非红细胞II血影蛋白在DNA内部链交联诱导范可尼贫血相关蛋白F（FANCA）和 核苷酸切除修复基因XPF募集到细胞核过程中的作用，采用M. Thelen 公司的XPF抗体用于免疫印迹和免疫沉淀实验。
INSIG1
insulin induced gene 1
总数:1
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. 2009 至该文献
为了研究知母皂甙AIII对肿瘤细胞造成细胞毒性的机制，使用了Biovision公司的抗INSIG-1抗体来进行蛋白印迹分析。
PODXL
podocalyxin-like
总数:2
Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression. 2004 至该文献
VIPR1
vasoactive intestinal peptide receptor 1
P2Y12
purinergic receptor P2Y, G-protein coupled, 12
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
FPR1
formyl peptide receptor 1
总数:2
Intravascular danger signals guide neutrophils to sites of sterile inflammation.. 2010 至该文献
为了研究中性粒细胞是如何从血液中募集到无菌炎症位点的机制，使用了R&D Systems公司的抗人FPR1抗体来进行流式细胞分析。 更多
beta-tubulin
tubulin, beta 1 class VI
总数:26
Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier. 2010 至该文献
为了研究类弹力蛋白多肽作为载体将抑细胞周期多肽靶向抑制卵巢癌细胞增殖，使用了Chemicon International的小鼠抗β-tubulin抗体来进行免疫印迹分析。 更多
GP1BA
glycoprotein Ib (platelet), alpha polypeptide
总数:5
High molecular weight kininogen regulates platelet-leukocyte interactions by bridging Mac-1 and glycoprotein Ib. 2003 至该文献
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
OCTN2
solute carrier family 22 (organic cation/carnitine transporter), member 5
SR-BI
scavenger receptor class B, member 1
总数:11
miR-33 Contributes to the Regulation of Cholesterol Homeostasis.. 2010 至该文献
为了研究内含子区的miRNA miR-33在胆固醇代谢调节中的功能，使用了Novus公司的兔抗SR-B1多克隆抗体来进行免疫印迹分析。 更多
STAB1
stabilin 1
NPC1
Niemann-Pick disease, type C1
总数:2
miR-33 Contributes to the Regulation of Cholesterol Homeostasis.. 2010 至该文献
为了研究内含子区的miRNA miR-33在胆固醇代谢调节中的功能，使用了Novus公司的兔抗NPC1多克隆抗体来进行免疫印迹分析。 更多
DRD3
dopamine receptor D3
总数:2
G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor. 2009 至该文献
为了研究在人的近曲小管细胞中GRK4对于D3受体信号传导的重要作用，使用了Zymed Laboratories公司的抗D3R单克隆抗体进行免疫印迹实验。 更多
RANBP9
RAN binding protein 9
PS1
presenilin 1
总数:12
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 至该文献
为了研究TNF-α对γ-分泌酶中作用，采用了Chemicon公司的兔抗APP碳末端抗体和鼠抗APP（6E10）抗体进行免疫印迹实验。 更多
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
总数:1
miR-33 Contributes to the Regulation of Cholesterol Homeostasis.. 2010 至该文献
为了研究内含子区的miRNA miR-33在胆固醇代谢调节中的功能，使用了Santa Cruz Biotechnology公司的抗HMGCR多克隆抗体来进行免疫印迹分析。
CD46
CD46 molecule, complement regulatory protein
总数:8
CD147/EMMPRIN acts as a functional entry receptor for measles virus on epithelial cells. 2010 至该文献
为了研究CD147/EMMPRIN作为麻疹病毒进入上皮细胞受体的功能使用了Hycult-Biotechnologies公司的鼠抗CD46单克隆抗体来进行蛋白印迹和流式细胞实验。 更多
血管性血友病因子 (von Willebrand factor)
总数:32
Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells. 2009 至该文献
为研究Rab27a和MyRIP对内皮细胞释放的血管假性血友病因子的调节作用，使用了Serotec公司的羊源性VWF抗体检测假性血友病因子。 更多
melanocortin 4 receptor
MAPRE1
microtubule-associated protein, RP/EB family, member 1
总数:3
Mammalian end binding proteins control persistent microtubule growth. 2009 至该文献
为了说明哺乳动物末端结合蛋白调控着微管的持续生长，使用了BD Biosciences公司的抗EB1鼠单克隆抗体来进行免疫组化实验和蛋白印迹实验。 更多
ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
总数:7
Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells. 2009 至该文献
为了研究MuPAR和纤溶酶在调控HSPCs和HSCs增殖，骨髓池大小，寻靶，移植物移入及活动中的作用，使用了eBioscience公司的抗alpha4beta1抗体，进行了免疫组织化学实验。 更多
CAR
coxsackie virus and adenovirus receptor
总数:8
Coxsackievirus and adenovirus receptor expression in human endometrial adenocarcinoma: possible clinical implications. 2008 至该文献
促甲状腺激素受体 (thyrotropin receptor)
thyroid stimulating hormone receptor
总数:1
Evidence for protein and mRNA TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy (TAO) after adipocytic differentiation. 2005 至该文献
β1整合素 (beta1 integrin)
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
总数:84
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 至该文献
为了研究乳癌细胞中由uPAR介导的细胞信号转导激发的特性，采用了Biolegend的抗CD29-FITC抗体进行流式细胞实验。 更多
整合素α5 (integrin alpha5)
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
总数:30
The CXC-chemokine CXCL4 interacts with integrins implicated in angiogenesis. 2008 至该文献
为了研究整合蛋白能够与CXCL4相互作用并参与血管生成，采用Chemicon的单抗alpha5抗体进行阻断实验。 更多
血管紧张素转化酶 (ACE)
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
总数:8
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 至该文献
为了研究通过定量蛋白质组学发现新的BACE1底物，采用Santa Cruz的ACE抗体以1:1,000稀释进行蛋白印迹实验。 更多
CD36
CD36 molecule (thrombospondin receptor)
总数:16
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 至该文献
为了说明在TRl信号通路的介导下间质干细胞能被极化成两种截然不同的表型，采用了eBiosciences公司的抗CD36抗体进行流式细胞术和免疫细胞化学实验。 更多
整合素α2 (integrin alpha2)
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
总数:14
Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. 2006 至该文献
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
总数:1
ADAMTS13 phenotype in plasma from normal individuals and patients with thrombotic thrombocytopenic purpura. 2007 至该文献
TRPA1
transient receptor potential cation channel, subfamily A, member 1
CCR5
chemokine (C-C motif) receptor 5
总数:28
Effects of ferumoxides-protamine sulfate labeling on immunomodulatory characteristics of macrophage-like THP-1 cells. 2008 至该文献
Biolegend 荧光素共轭的鼠抗人 CD195 免疫球蛋白G2a用于流式细胞术来演示吞噬的FePro纳米粒不能显著的影响THP-1细胞的免疫特性。 更多
髓过氧化酶 (myeloperoxidase)
总数:7
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation. 2010 至该文献
为了研究心房纤颤病理过程中髓过氧化物酶的作用，采用了Calbiochem公司的抗MPO（475915）抗体进行免疫组化实验。 更多
factor H
complement factor H
总数:12
Comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous GVHD. Evidence of defective function of factor H. 2010 至该文献
为了研究系统性硬化病病人和硬皮病样移植物抗宿主病病人中因子H功能的缺失，采用了AbD Serotec的小鼠单抗人FH抗体进行流式细胞分选实验。 更多
CD47
CD47 molecule
总数:4
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.. 2011 至该文献
为了研究人造血系统细胞给以不同刺激的反应能通过单细胞多因子分选进行分析，采用BD Biosciences的抗CD47抗体以2ug/ml浓度进行细胞多因子分选实验。 更多
KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
总数:3
Rab-GTPase-dependent endocytic recycling of Kv1.5 in atrial myocytes. 2007 至该文献
Chemicon的抗Kv1.5多克隆抗体被用于蛋白质印迹实验，来检测人HL-1细胞中未做标记的Kv1.5。 更多
CHRM3
cholinergic receptor, muscarinic 3
总数:3
Clathrin-mediated endocytosis of m3 muscarinic receptors. Roles for Gbetagamma and tubulin. 2004 至该文献
为了检测人体ＳＫ－Ｎ－ＳＨ成神经瘤细胞中ｍ３毒蕈碱受体，使用了Santa Cruz Biotechnology公司的抗ｍ３毒蕈碱受体抗体，进行了免疫印迹实验，并且为了确定ｍ３毒蕈碱受体仅限于人体ＳＫ－Ｎ－ＳＨ成神经瘤细胞中，使用此抗体，进行了免疫细胞化学实验。 更多
PTH1R
parathyroid hormone 1 receptor
总数:3
Effect of parathyroid-hormone-related protein on human platelet activation. 2007 至该文献
Santa Cruz Biotechnology的亲和层析小鼠抗PTH1R单克隆抗体被用于蛋白质印迹实验，来确定急性心肌梗塞（AMI）病人发作和没有发作时血小板中PTH1R。此外Santa Cruz Biotechnology的结合FITC的抗PTH1R抗体被用于流式细胞术，来检测AMI发作病人和具有相似的心血管危险因子却没患AMI的病人的血小板表面PTH1R的表达。 更多
thromboxane A2 receptor
总数:2
The mechanism of oxidative stress stabilization of the thromboxane receptor in COS-7 cells. 2004 至该文献
SDC4
syndecan 4
总数:3
Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans. 2008 至该文献
Santa Cruz公司生产的多配体蛋白聚糖-4抗体可用于免疫细胞化学实验，来研究类肝素酶在细胞的黏附及扩散中的作用。 更多
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
总数:7
The nucleocapsid protein of severe acute respiratory syndrome coronavirus inhibits cell cytokinesis and proliferation by interacting with translation elongation factor 1alpha. 2008 至该文献
F10
coagulation factor X
总数:2
Extrahepatic synthesis of factor VII in human atherosclerotic vessels. 2003 至该文献
apoA-I
apolipoprotein A-I
总数:13
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 至该文献
为了在一个转基因小鼠模型中研究载脂蛋白成员的不同作用，采用 Abcam公司的兔多克隆抗apoA-I抗体产品(1:10,000)，进行了免疫印迹实验。 更多
podoplanin
总数:4
Altered regulation of Prox1-gene-expression in liver tumors. 2008 至该文献
CD16
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
总数:41
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy.. 2011 至该文献
为了研究在天然杀伤细胞免疫突触处皮质肌动蛋白的重塑，采用了R&D systems的抗CD16抗体进行免疫细胞化学实验。 更多
胰岛素受体 (insulin receptor)
总数:22
Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers. 2009 至该文献
为验证以下假说，即：胰岛素信号提供了对抗Aβ衍生的可扩散性突触毒性的生理防御机制，将Santa Cruz提供的兔多克隆抗胰岛素受体alpha亚单位抗体用于蛋白免疫印迹和免疫细胞化学实验中。 更多
CD18
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
总数:21
CBF{beta} is critical for AML1-ETO and TEL-AML1 activity. 2009 至该文献
CNR1
cannabinoid receptor 1 (brain)
总数:3
Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. 2008 至该文献
为了确认内源性大麻素信号途径的关键元件是否在骨关节炎和类风湿性关节炎患者的关节骨液中表达，采用了Calbiochem公司的抗大麻素受体1抗体进行了蛋白印迹实验。 更多
囊性纤维化跨膜电导调节因子 (CFTR)
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
总数:17
Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. 2009 至该文献
为了研究铜绿假单胞菌外膜囊泡对细菌致病基因的远程运输，使用了Upstate Biotechnology公司的CFTR鼠抗(clone M3A7)来进行免疫印记实验。 更多
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
总数:2
Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in endothelial cells by nitric oxide deficiency. 2004 至该文献
为了阐明不对称二甲基精氨酸的水平，采用了Sigma公司的鼠抗LOX-1的多克隆抗体进行蛋白质印迹分析 更多