COS细胞
基因
试剂
文献样例
产品评述样例
促甲状腺激素受体 (thyrotropin receptor)
thyroid stimulating hormone receptor
总数:1
Evidence for protein and mRNA TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy (TAO) after adipocytic differentiation. 2005 至该文献
因子V (factor V)
coagulation factor V (proaccelerin, labile factor)
总数:4
Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation. 2009 至该文献
为了研究魁北克血小板障碍病中uPA的高表达和巨核细胞分化的关联,使用了Affinity Biologicals公司的羊抗凝血因子V抗体来进行免疫荧光实验。 更多
雄激素受体 (androgen receptor)
总数:50
Estrogen receptor-{beta} activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNF{alpha} mediated. 2010 至该文献
为了研究雌激素受体beta激活的凋亡的调节机制和它的拮抗物在癌症治疗中的作用,使用了Santa Cruz Biotechnology公司的抗雄激素受体抗体来进行免疫组化试验。 更多
MYOT
myotilin
总数:1
Evidence for a dominant-negative effect in ACTA1 nemaline myopathy caused by abnormal folding, aggregation and altered polymerization of mutant actin isoforms. 2004 至该文献
SHIP2
inositol polyphosphate phosphatase-like 1
UBC
ubiquitin C
总数:4
Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family. 2007 至该文献
为了研究人切片中PGRN的遗传变异性是否与其他的神经变性疾病有关,比如阿尔茨海默病(AD)或者帕金森病(PD),采用了Dako公司的抗泛素的抗体进行免疫组织化学分析。 更多
CYP11B1
cytochrome P450, family 11, subfamily B, polypeptide 1
RAMP3
receptor (G protein-coupled) activity modifying protein 3
secretin receptor
总数:1
Secretin-receptor and secretin-receptor-variant expression in gastrinomas: correlation with clinical and tumoral features and secretin and calcium provocative test results. 2007 至该文献
NR3C2
nuclear receptor subfamily 3, group C, member 2
ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
总数:1
Syntaxin-1A inhibits cardiac KATP channels by its actions on nucleotide binding folds 1 and 2 of sulfonylurea receptor 2A. 2004 至该文献
FOXL2
forkhead box L2
总数:3
The forkhead transcription factor foxl2 is sumoylated in both human and mouse: sumoylation affects its stability, localization, and activity. 2010 至该文献
为了找到叉头转录因子2相互作用的分子,发现苏素化对于维持叉头转录因子2的功能有着重要的作用,采用了ABCAM公司FOXL2抗体,进行细胞免疫荧光实验。 更多
HDAC5
histone deacetylase 5
总数:6
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. 2009 至该文献
为了研究CaMKII在调控血压过载诱导的小鼠心肌肥厚到心脏衰竭中的作用,采用了Assay Biotech公司的抗磷酸化HDAC5(Ser498)抗体产品 ,进行了免疫印迹实验 更多
GLB1
galactosidase, beta 1
总数:7
Conditional Knockout of NMDA Receptors in Dopamine Neurons Prevents Nicotine-Conditioned Place Preference. 2010 至该文献
为了研究NMDA受体在多巴胺神经元中对尼古丁条件下场所选择的调控作用,使用了Invitrogene公司的抗beta-Galactosidase抗体,来免疫荧光染色,进行了免疫细胞化学实验。 更多
TGFBR3
transforming growth factor, beta receptor III
总数:1
A direct interaction between transforming growth factor (TGF)-betas and amyloid-beta protein affects fibrillogenesis in a TGF-beta receptor-independent manner. 2003 至该文献
CDC37
cell division cycle 37 homolog (S. cerevisiae)
总数:5
Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import. 2007 至该文献
为了研究热休克蛋白分子伴侣DJA1、DJA2 和 DJA4在一种基于线粒体外膜受体蛋白运输过程与前蛋白的相互作用机制,采用了Affinity BioReagents公司的辅伴侣蛋白Cdc37抗体,进行蛋白质印记实验。 更多
CAPN3
calpain 3, (p94)
总数:1
Mutations in the fukutin-related protein gene (FKRP) identify limb girdle muscular dystrophy 2I as a milder allelic variant of congenital muscular dystrophy MDC1C. 2001 至该文献
GLA
galactosidase, alpha
总数:2
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 至该文献
为了研究在非典型的法布瑞氏病中脱氧半乳糖苷野尻霉素具有增强半乳糖苷酶活性和增加该酶表达的作用,使用了Santa Cruz公司的半乳糖苷酶多克隆抗体进行蛋白印迹实验。 更多
GRIK2
glutamate receptor, ionotropic, kainate 2
总数:2
TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses. 2005 至该文献
Upstate Biotechnology的GluR6抗体被用于蛋白质印迹实验,来研究在海马Schaffer侧肢突触的建立中TrkB的细胞自主性功能。 更多
糖皮质激素受体 (glucocorticoid receptor)
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
总数:20
Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors. 2009 至该文献
为了说明HSP90伴侣蛋白Cdc37能维持致癌蛋白激酶客户蛋白,使用了Santa Cruz Biotechnology公司的GR抗体进行蛋白印迹实验。 更多
OAT1
solute carrier family 22 (organic anion transporter), member 6
总数:4
Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice. 2006 至该文献
TNK2
tyrosine kinase, non-receptor, 2
总数:5
Human SIRT6 promotes DNA end resection through CtIP deacetylation.. 2010 至该文献
为了阐明SIRT6促进DNADNA末端切除的机制,使用了Biomol公司的小鼠抗AcK-2抗体来进行免疫印迹分析。 更多
USP36
ubiquitin specific peptidase 36
SUMO-1
SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
总数:40
A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis.. 2011 至该文献
为了研究myc依赖的癌症需要SUMO化修饰来促进肿瘤发生,采用Abcam的抗SUMO1抗体进行蛋白印迹实验。 更多
GNRHR
gonadotropin-releasing hormone receptor
总数:5
Evidence for LHRH-receptor expression in human airway epithelial (Calu-3) cells and its role in the transport of an LHRH agonist. 2004 至该文献
Src
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
总数:116
miR-126 regulates angiogenic signaling and vascular integrity. 2008 至该文献
为了研究miR-126对血管完整性和血管生成的调控作用,采用了Cell Signaling的抗SRC和抗磷酸化SRC (Tyr416)抗体进行免疫印迹实验。 更多
PTH1R
parathyroid hormone 1 receptor
总数:3
Effect of parathyroid-hormone-related protein on human platelet activation. 2007 至该文献
Santa Cruz Biotechnology的亲和层析小鼠抗PTH1R单克隆抗体被用于蛋白质印迹实验,来确定急性心肌梗塞(AMI)病人发作和没有发作时血小板中PTH1R。此外Santa Cruz Biotechnology的结合FITC的抗PTH1R抗体被用于流式细胞术,来检测AMI发作病人和具有相似的心血管危险因子却没患AMI的病人的血小板表面PTH1R的表达。 更多
ARRB2
arrestin, beta 2
总数:4
Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation. 2006 至该文献
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
总数:1
Colocalization of P450c17 and cytochrome b5 in androgen-synthesizing tissues of the human. 2004 至该文献
14 3 3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
总数:21
Repressive LTR Nucleosome Positioning by the BAF Complex Is Required for HIV Latency.. 2011 至该文献
为了研究SWI/SNF在潜伏期HIV LTR转录激活前后的调节作用,采用了Santa Cruz Biotechnology 14-3-3进行了蛋白质免疫印迹实验。 更多
PIAS1
protein inhibitor of activated STAT, 1
总数:3
Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone. 2006 至该文献
为了研究cAMP信号介导的小类泛素修饰因子旁路的动态变化决定子宫内膜对孕酮反应的过程,采用了Santa Cruz Biotechnology的抗PIAS1(8152)抗体进行免疫印迹试验。 更多
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
总数:1
Decreased expression of membrane IL-5 receptor alpha on human eosinophils: I. Loss of membrane IL-5 receptor alpha on airway eosinophils and increased soluble IL-5 receptor alpha in the airway after allergen challenge. 2002 至该文献
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
总数:6
Association of protein kinase A with AKAP150 facilitates pepsinogen secretion from gastric chief cells. 2001 至该文献
CCDC88A
coiled-coil domain containing 88A
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
WNK4
WNK lysine deficient protein kinase 4
总数:2
WNK kinases regulate thiazide-sensitive Na-Cl cotransport. 2003 至该文献
SLC26A4
solute carrier family 26, member 4
总数:2
Localization of the ammonium transporter proteins RhBG and RhCG in mouse kidney. 2003 至该文献
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
EPS15
epidermal growth factor receptor pathway substrate 15
总数:3
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors. 2009 至该文献
为了研究脂质筏依赖的Fc secre tRI泛素化作用对受体的内吞调控过程中所起的作用,使用了Santa Cruz公司的抗Eps15抗体来进行蛋白印迹分析。 更多
EPM2A
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
AGTR1
angiotensin II receptor, type 1
总数:9
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 至该文献
为了研究缺血性心脏病病人体内ETB和AT1受体表达量上调,采用Santa Cruz的兔抗AT1抗体进行免疫组织化学实验。 更多
UBE2I
ubiquitin-conjugating enzyme E2I
总数:10
The forkhead transcription factor foxl2 is sumoylated in both human and mouse: sumoylation affects its stability, localization, and activity. 2010 至该文献
为了找到叉头转录因子2相互作用的分子,发现苏素化对于维持叉头转录因子2的功能有着重要的作用,采用了Santa Cruz公司泛素结合酶E2I抗体,进行蛋白质印记实验。 更多
WWP2
WW domain containing E3 ubiquitin protein ligase 2
ARF1
ADP-ribosylation factor 1
总数:8
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication. 2007 至该文献
为了研究Arf与脊髓灰质炎病毒蛋白3CD之间的相互作用及其对脊髓灰质炎病毒扩增的影响,使用了Affinity Bioreagents公司的抗Arf抗体进行免疫印迹试验。 更多
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
总数:2
Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide cross-linking of substituted cysteines. 2009 至该文献
为了定位在钾离子通道中的KCNE1和KCNQ1,采用了Santa Cruz的羊抗Q1抗体进行免疫印迹分析。 更多
Bag-1
BCL2-associated athanogene
总数:7
SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs. 2009 至该文献
为了说明SMD和NMD在肌细胞生成中的作用,使用了Santa Cruz Biotechnologies公司的BAG1抗体来进行蛋白印迹实验。 更多
KCNIP2
Kv channel interacting protein 2
总数:3
Transmural expression of transient outward potassium current subunits in normal and failing canine and human hearts. 2004 至该文献
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
总数:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 至该文献
为了说明在人NT2细胞中血管活性肠肽可以促进HCMV MIE的表达,使用了Santa Cruz Biotechnology公司的兔多克隆抗PKA催化亚基抗体来进行蛋白印迹实验。 更多
STK4
serine/threonine kinase 4
总数:1
Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis. 2006 至该文献
Cell Signaling公司的兔源性Mst1多克隆抗体可用于免疫印迹实验,来检测人 293T and U2OS细胞中Mst1的表达。
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
总数:1
Host factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol. 2010 至该文献
为研究细胞内F. tularensis细菌的吞噬体发生和增值的调节,采用了Proteintech group公司的抗PI4KCA抗体进行蛋白质印迹试验。
SUMO2
SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
总数:7
A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis.. 2011 至该文献
为了研究myc依赖的癌症需要SUMO化修饰来促进肿瘤发生,采用Abcam的抗SUMO2/3抗体进行蛋白印迹实验。 更多
ATXN3
ataxin 3
总数:2
Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence. 2007 至该文献
PLD2
phospholipase D2
总数:1
Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a phospholipase D2 pathway. 2005 至该文献
ROR2
receptor tyrosine kinase-like orphan receptor 2
总数:2
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. 2010 至该文献
为了研究ROR2调节转移性黑色素瘤的Wnt5A,采用Cell Signaling公司的ROR2抗体,进行了细胞免疫荧光实验。 更多
ER
estrogen receptor 1
总数:108
The relationship of cerb B 2 expression with estrogen receptor and progesterone receptor and prognostic parameters in endometrial carcinomas. 2010 至该文献
为了研究c-erbB-2的表达量对子宫内膜癌的影响,使用了Spring Bioscience公司的ER兔单抗(M3011, 1:100稀释)来进行免疫组化实验。 更多
PNPLA2
patatin-like phospholipase domain containing 2
总数:1
Adipose triglyceride lipase (ATGL) expression in human skeletal muscle is type I (oxidative) fiber specific. 2008 至该文献
PCAF
K(lysine) acetyltransferase 2B
总数:15
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 至该文献
为了说明IRF5同HATs和HDACs一起调控促炎细胞因子的转录水平表达,使用了Upstate Biotechnology公司的抗PCAF抗体进行蛋白印迹实验。 更多
GPER
G protein-coupled estrogen receptor 1
总数:2
Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression. 2006 至该文献
DPYSL2
dihydropyrimidinase-like 2
总数:2
Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3. 2009 至该文献
为证实突变的SOD1可以通过隔离KAP3来降低轴突的胆碱乙酰转移酶运输量和乙酰胆碱的释放量,使用了Immuno-Biological Laboratories公司的抗CRMP-2抗体来进行蛋白印迹分析。 更多
LEF1
lymphoid enhancer-binding factor 1
总数:5
Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression. 2009 至该文献
为了研究AEG1在调节肝癌发病机制中的功能,使用了Cell Signaling Technology公司的兔抗LEF1多克隆抗体来进行免疫印迹分析和免疫荧光试验。 更多
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
总数:6
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons. 2007 至该文献
为了研究在Purkinje神经元细胞膜钙ATP酶2缺失的小脑的分子变化,采用了Calbiochem公司的IP3R1抗体进行蛋白质印迹杂家和免疫组织化学分析。 更多
NR5A2
nuclear receptor subfamily 5, group A, member 2
总数:2
Tumor necrosis factor alpha-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis. 2003 至该文献
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
总数:6
Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure. 2009 至该文献
为了研究Myc在介导肥厚型心肌病和心衰中的功能,使用了Santa Cruz Biotechnology公司的兔抗PGC-1α多克隆抗体来进行免疫组化实验。 更多
SUMO3
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
总数:1
Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein. 2006 至该文献
ARRB1
arrestin, beta 1
总数:7
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 至该文献
为了说明arrestin-2/STAM-1复合体通过泛素化HRS调节CXCR4溶酶体分选,使用了Santa Cruz Biotechnology公司的beta-arrestin1/2兔多抗(21-B1)来进行免疫印记实验。 更多
RASSF1A
Ras association (RalGDS/AF-6) domain family member 1
总数:4
Mutational inactivation of STAG2 causes aneuploidy in human cancer.. 2011 至该文献
为了研究人肿瘤细胞中染色体的异倍性与STAG2的失活相关,采用Santa Cruz的抗RASSF1A抗体进行蛋白印迹实验。 更多
GATA-2
GATA binding protein 2
总数:4
Cross talk between retinoic acid signaling and transcription factor GATA-2. 2004 至该文献
Hsc70
heat shock 70kDa protein 8
总数:25
{alpha}-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro.. 2010 至该文献
为了确定人腺病毒的原子结构,使用了SYSY公司的抗Hsc70单克隆抗体来进行免疫印迹分析。 更多
UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
总数:2
Two molecular pathways (NMD and ERAD) contribute to a genetic epilepsy associated with the GABA(A) receptor GABRA1 PTC mutation, 975delC, S326fs328X. 2009 至该文献
为了研究GABAA受体α1突变致NMD和ERAD活性增强而导致的遗传性癫痫,采用了San Diego公司生产的抗人Upf-1多克隆抗体用于免疫印迹实验。 更多
VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor
总数:15
Vitamin d induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 至该文献
为了说明在膀胱中维生素D可以诱导一种人类抗菌肽cathelicidin的表达,采用了Affinity BioReagents公司的抗VDR(MA1-710,1:400)单克隆抗体进行免疫细胞化学实验。 更多