COS细胞
基因
试剂
文献样例
产品评述样例
雄激素受体 (androgen receptor)
总数:52
Overcoming mutation-based resistance to antiandrogens with rational drug design. 2013 至该文献
为了研究非基于突变治疗雄激素抵抗性前列腺癌的合理药物设计,采用了Upstate的抗雄激素受体(PG-21)抗体进行染色质免疫沉淀。 更多
UBC
ubiquitin C
总数:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 至该文献
为了研究突触的可塑性,采用了Enzo Life Sciences的抗Ubiquitin的抗体进行了免疫印迹实验。 更多
促甲状腺激素受体 (thyrotropin receptor)
thyroid stimulating hormone receptor
总数:1
Evidence for protein and mRNA TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy (TAO) after adipocytic differentiation. 2005 至该文献
因子V (factor V)
coagulation factor V
总数:4
Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation. 2009 至该文献
为了研究魁北克血小板障碍病中uPA的高表达和巨核细胞分化的关联,使用了Affinity Biologicals公司的羊抗凝血因子V抗体来进行免疫荧光实验。 更多
PAX9
paired box 9
总数:1
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 2009 至该文献
为了说明PAX 5可以在小肺癌细胞中表达并能调控c-Met的转录,使用了Abcam公司的PAX 9多克隆抗体进行蛋白印迹实验。
SUMO-1 (SUMO-1)
small ubiquitin-like modifier 1
总数:40
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 至该文献
为了研究myc依赖的癌症需要SUMO化修饰来促进肿瘤发生,采用Abcam的抗SUMO1抗体进行蛋白印迹实验。 更多
糖皮质激素受体 (glucocorticoid receptor)
nuclear receptor subfamily 3 group C member 1
总数:20
Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus. 2009 至该文献
为了研究移动的cDCs在调控CD11c, MHC II, 和CD86中的作用,使用了BD公司的鼠单克隆抗鼠Gr-l抗体,进行了免疫流式细胞计量分析。 更多
FOXL2
forkhead box L2
总数:3
The forkhead transcription factor Foxl2 is sumoylated in both human and mouse: sumoylation affects its stability, localization, and activity. 2010 至该文献
为了找到叉头转录因子2相互作用的分子,发现苏素化对于维持叉头转录因子2的功能有着重要的作用,采用了ABCAM公司FOXL2抗体,进行细胞免疫荧光实验。 更多
胰液受体 (secretin receptor)
总数:1
Secretin-receptor and secretin-receptor-variant expression in gastrinomas: correlation with clinical and tumoral features and secretin and calcium provocative test results. 2007 至该文献
MAPK10
mitogen-activated protein kinase 10
总数:4
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 至该文献
为了研究TNF-α对γ-分泌酶中作用,采用了Abgent公司的兔抗JNK3抗体进行免疫印迹实验。 更多
SUMO2
small ubiquitin-like modifier 2
总数:7
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. 2012 至该文献
为了研究myc依赖的癌症需要SUMO化修饰来促进肿瘤发生,采用Abcam的抗SUMO2/3抗体进行蛋白印迹实验。 更多
RAMP3
receptor activity modifying protein 3
CDC37
cell division cycle 37
总数:5
Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import. 2007 至该文献
为了研究热休克蛋白分子伴侣DJA1、DJA2 和 DJA4在一种基于线粒体外膜受体蛋白运输过程与前蛋白的相互作用机制,采用了Affinity BioReagents公司的辅伴侣蛋白Cdc37抗体,进行蛋白质印记实验。 更多
AVPR2
arginine vasopressin receptor 2
总数:1
Inherent sexually dimorphic expression of hepatic CYP2C12 correlated with repressed activation of growth hormone-regulated signal transduction in male rats. 2008 至该文献
使用Cell Signaling技术公司的磷酸化Erk1和Erk2 (磷酸化-p42/p44 MAPK)抗体进行免疫印迹实验来证明持续的GH通过GHR激活Erk1和Erk2引起CYP2C12表达增加。
SHIP2
inositol polyphosphate phosphatase like 1
GRIK2
glutamate ionotropic receptor kainate type subunit 2
总数:2
TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses. 2005 至该文献
Upstate Biotechnology的GluR6抗体被用于蛋白质印迹实验,来研究在海马Schaffer侧肢突触的建立中TrkB的细胞自主性功能。 更多
ASIC3
acid sensing ion channel subunit 3
总数:2
ASIC3 in muscle mediates mechanical, but not heat, hyperalgesia associated with muscle inflammation. 2007 至该文献
为研究酸感受离子通道亚基3 (ASIC3)在肌炎诱导的表皮痛觉增敏中的作用,采用Chemicon 公司的ASIC3抗体用于免疫组化和 ELISA 实验。 更多
OAT1
solute carrier family 22 member 6
总数:4
Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice. 2006 至该文献
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
MCF2
MCF.2 cell line derived transforming sequence
总数:1
Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1. 2008 至该文献
为了证明Nm23-H1可以通过调节Dbl1的活性负调控细胞迁移和肿瘤转移,采用了Santa Cruz兔抗Dbl-1抗体进行了免疫沉淀和免疫印记实验。
ARRB2
arrestin beta 2
总数:3
Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation. 2006 至该文献
MCFD2
multiple coagulation factor deficiency 2
ATXN3
ataxin 3
总数:1
Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence. 2007 至该文献
NHLRC1
NHL repeat containing E3 ubiquitin protein ligase 1
Src
SRC proto-oncogene, non-receptor tyrosine kinase
总数:120
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 至该文献
为了研究在管腔乳腺癌中雌激素敏感性以及抗雌激素抗性的获得,采用了Calbiochem的抗SRC抗体进行了western blot实验。 更多
UBE2I
ubiquitin conjugating enzyme E2 I
总数:10
The forkhead transcription factor Foxl2 is sumoylated in both human and mouse: sumoylation affects its stability, localization, and activity. 2010 至该文献
为了找到叉头转录因子2相互作用的分子,发现苏素化对于维持叉头转录因子2的功能有着重要的作用,采用了Santa Cruz公司泛素结合酶E2I抗体,进行蛋白质印记实验。 更多
HDAC5
histone deacetylase 5
总数:6
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. 2009 至该文献
为了研究CaMKII在调控血压过载诱导的小鼠心肌肥厚到心脏衰竭中的作用,采用了Assay Biotech公司的抗磷酸化HDAC5(Ser498)抗体产品 ,进行了免疫印迹实验 更多
NCOA2
nuclear receptor coactivator 2
总数:6
Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. 2006 至该文献
SMAD6
SMAD family member 6
总数:2
Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells. 2008 至该文献
为了阐明一种蛋白酶抑制剂的与结肠癌骨信号有关的抗有丝分裂效应,采用了细胞信号技术公司的抗-Smad6抗体进行了蛋白印迹实验。 更多
EPS15
epidermal growth factor receptor pathway substrate 15
总数:3
Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors. 2009 至该文献
为了研究脂质筏依赖的Fc secre tRI泛素化作用对受体的内吞调控过程中所起的作用,使用了Santa Cruz公司的抗Eps15抗体来进行蛋白印迹分析。 更多
GLB1
galactosidase beta 1
总数:7
Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. 2010 至该文献
为了研究NMDA受体在多巴胺神经元中对尼古丁条件下场所选择的调控作用,使用了Invitrogene公司的抗beta-Galactosidase抗体,来免疫荧光染色,进行了免疫细胞化学实验。 更多
GNPTA
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
USP36
ubiquitin specific peptidase 36
PCSK7
proprotein convertase subtilisin/kexin type 7
ER
estrogen receptor 1
总数:112
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. 2012 至该文献
为了研究在管腔乳腺癌中雌激素敏感性以及抗雌激素抗性的获得,采用了Santa Cruz 的抗ERa抗体进行了western blot实验。 更多
GLA
galactosidase alpha
总数:2
Effects of a chemical chaperone on genetic mutations in alpha-galactosidase A in Korean patients with Fabry disease. 2009 至该文献
为了研究在非典型的法布瑞氏病中脱氧半乳糖苷野尻霉素具有增强半乳糖苷酶活性和增加该酶表达的作用,使用了Santa Cruz公司的半乳糖苷酶多克隆抗体进行蛋白印迹实验。 更多
DUOX2
dual oxidase 2
总数:1
Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells. 2009 至该文献
为了研究如何调节功能性Duox-DuoxA异源二聚体的胞内定位,使用了Abgent公司的兔抗Duox2抗体进行免疫印迹实验。
RND3
Rho family GTPase 3
总数:3
RhoE Is required for keratinocyte differentiation and stratification. 2009 至该文献
为研究RhoE在角质化细胞的分化和层化过程中所发挥的角色,将密理博公司提供的小鼠单克隆抗RhoE抗体(4)用于蛋白免疫印迹实验中。 更多
ERBB4
erb-b2 receptor tyrosine kinase 4
总数:20
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 2009 至该文献
为了鉴定ERBB4基因的突变在黑素瘤中所起的作用,使用了Santa Cruz Biotechnology公司的抗体ERBB4来进行免疫共沉淀和免疫印迹分析。 更多
PRKACA
protein kinase cAMP-activated catalytic subunit alpha
总数:20
Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. 2009 至该文献
为了说明在人NT2细胞中血管活性肠肽可以促进HCMV MIE的表达,使用了Santa Cruz Biotechnology公司的兔多克隆抗PKA催化亚基抗体来进行蛋白印迹实验。 更多
BMPR1B
bone morphogenetic protein receptor type 1B
总数:3
BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1. 2005 至该文献
为了研究成熟人B细胞中BMP-6能够调控Smad磷酸化,Id1表达以及细胞生长,采用R & D Systems的抗BMP-RIB抗体进行蛋白印迹实验。 更多
STK4
serine/threonine kinase 4
总数:1
Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis. 2006 至该文献
Cell Signaling公司的兔源性Mst1多克隆抗体可用于免疫印迹实验,来检测人 293T and U2OS细胞中Mst1的表达。
TNK2
tyrosine kinase non receptor 2
总数:5
为了阐明SIRT6促进DNADNA末端切除的机制,使用了Biomol公司的小鼠抗AcK-2抗体来进行免疫印迹分析。 更多
GGA3
golgi associated, gamma adaptin ear containing, ARF binding protein 3
总数:2
PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal. 2007 至该文献
为了研究PI4P同GGA的关系,采用了BD Transduction Laboratories公司的多克隆抗GGA3抗体,进行了免疫荧光实验。 更多
SUMO3
small ubiquitin-like modifier 3
总数:1
Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein. 2006 至该文献