deactivation of the beta-catenin transactivating complex
基因
试剂
文献样例
产品评述样例
14 3 3 protein zeta
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
总数:6
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 至该文献
14-3-3ζ抗体,进行蛋白质印迹实验。 更多
Akt
AKT serine/threonine kinase 1
总数:423
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. 2013 至该文献
为了研究磷酸肌醇激酶3在调节细胞因子依赖性细胞存活中的作用,采用了Cell Signalling公司的抗磷酸化Ser473Akt抗体进行了免疫印迹试验。 更多
APC
APC regulator of WNT signaling pathway
总数:11
A cell motility screen reveals role for MARCKS-related protein in adherens junction formation and tumorigenesis. 2009 至该文献
为了研究MRP蛋白在粘着连接形成和肿瘤发生过程中起重要作用,采用Calbiochem的APC抗体进行免疫细胞化学实验。 更多
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit
总数:2
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 至该文献
为了阐明c-Myb在MLL相关白血病中的作用,实验使用了Bethyl Laboratories公司的抗Ash2L抗体进行免疫共沉淀。 更多
beta连环蛋白 (beta-catenin)
catenin beta 1
总数:154
Wnt/?-catenin signaling regulates telomerase in stem cells and cancer cells. 2012 至该文献
为了研究端粒酶受Wnt/beta-catenin信号调控,采用了Millipore的抗beta-catenin抗体进行ChIP实验。 更多
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
总数:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 至该文献
为了研究FANCM在有丝分裂过程中的降解机制,使用了Zymed Laboratories的小鼠抗β-TRCP抗体来进行免疫印迹分析。 更多
CBY1
chibby family member 1, beta catenin antagonist
CtBP1
C-terminal binding protein 1
总数:4
Loss of full length CtBP1 expression enhances the invasive potential of human melanoma. 2009 至该文献
HDAC1
histone deacetylase 1
总数:54
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 至该文献
为了说明IRF5同HATs和HDACs一起调控促炎细胞因子的转录水平表达,使用了Upstate Biotechnology公司的抗HDAC1抗体进行蛋白印迹实验。 更多
ICAT
catenin beta interacting protein 1
总数:12
A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta. 2013 至该文献
为了研究Gcm1和Fzd5在调控滋养层细胞分化和绒毛膜分支位点的作用,采用了Millipore抗active-beta-catenin抗体进行了免疫组化实验。 更多
LEF1
lymphoid enhancer binding factor 1
总数:5
Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression. 2009 至该文献
为了研究AEG1在调节肝癌发病机制中的功能,使用了Cell Signaling Technology公司的兔抗LEF1多克隆抗体来进行免疫印迹分析和免疫荧光试验。 更多
多发性内分泌腺瘤综合征1型 (MEN1)
menin 1
总数:2
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 至该文献
为了阐明c-Myb在MLL相关白血病中的作用,实验使用了Bethyl Laboratories公司的抗menin抗体进行免疫共沉淀。 更多
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit
总数:4
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination. 2010 至该文献
为了研究PTIP促进特异性的染色质改变和免疫球蛋白类别转换重组的机制,使用了Bethyl公司的抗RBBP5抗体来进行染色质免疫沉淀实验。 更多
RPS27A
ribosomal protein S27a
总数:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 至该文献
为了在内质网相关蛋白的降解途径(ERAD)中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能,使用了Santa Cruz Biotechnology公司的抗体ubiquitin来进行免疫印迹分析。 更多
TCF7L1
transcription factor 7 like 1
总数:2
Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen. 2008 至该文献
为了证明Erα与β-catenin/Lef-1/Tcf-3信号的整合,是子宫中雌激素依赖的内源基因调控的必要过程,采用了Santa Cruz Biotechnology的经亲和纯化的Tcf-3抗体,进行免疫沉淀反应和蛋白质印迹 更多
TCF7L2
transcription factor 7 like 2
总数:6
Growth inhibition of human colon cancer cell line HCT116 by bis[2-(acylamino)phenyl] disulfide and its action mechanism. 2008 至该文献
为了研究bis[2-(acylamino)phenyl] disulfide诱导的生长抑制的作用机制,采用了Upstate Biotechnology公司的TCF-4抗体进行免疫共沉淀实验及蛋白免疫印迹实验。 更多
TLE1
TLE family member 1, transcriptional corepressor
总数:1
Esg1, expressed exclusively in preimplantation embryos, germline, and embryonic stem cells, is a putative RNA-binding protein with broad RNA targets. 2006 至该文献
TLE2
TLE family member 2, transcriptional corepressor
TLE3
TLE family member 3, transcriptional corepressor
TLE4
TLE family member 4, transcriptional corepressor
UBC
ubiquitin C
总数:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 至该文献
为了研究突触的可塑性,采用了Enzo Life Sciences的抗Ubiquitin的抗体进行了免疫印迹实验。 更多
泛肽 (ubiquitin)
ubiquitin B
总数:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 至该文献
为了阐明BCL6和HB-EGF-CTF相互作用,并且这种相互作用可能会引起细胞周期蛋白D2在人胃癌细胞中表达,采用了Cell Signaling Technology公司的小鼠抗泛素单克隆抗体,进行了蛋白质印迹实验。 更多
XIAP
X-linked inhibitor of apoptosis
总数:28
Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance. 2009 至该文献
为研究PARP-1在电离辐射诱导的NF-κB信号级联放大过程中所起的作用,将R&D systems提供的抗XIAP抗体用于蛋白免疫印迹实验中。 更多
XPO1
exportin 1
总数:7
Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis. 2009 至该文献
为了研究LKB1在核浆转运过程中的作用,采用了Santa Cruz Biotechnology公司的CRM-1抗体进行蛋白印迹实验。 更多