疾病易感性
基因
试剂
文献样例
产品评述样例
MBL2
mannose-binding lectin (protein C) 2, soluble
总数:4
Protein kinase CK2 phosphorylation regulates the interaction of Kaposi's sarcoma-associated herpesvirus regulatory protein ORF57 with its multifunctional partner hnRNP K. 2004 至该文献
CD32
Fc fragment of IgG, low affinity IIa, receptor (CD32)
总数:7
Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcgammaRIIa and the integrin beta3 cytoplasmic domain. 2009 至该文献
为探讨依替巴肽引起的血小板减少症和血栓形成的病因学,将BD Biosciences — Pharmingen提供的FITC标记的单克隆抗FcγRIIa抗体用于蛋白免疫印迹实验中。 更多
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
总数:6
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.. 2011 至该文献
为了研究人造血系统细胞给以不同刺激的反应能通过单细胞多因子分选进行分析,采用Biolegend的抗HLADR抗体以2ug/ml浓度进行细胞多因子分选实验。 更多
MEKK1
mitogen-activated protein kinase kinase kinase 1
总数:15
TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. 2008 至该文献
为了证明TACE在结肠直肠癌细胞中可以抑制EGFR通路,采用了Cell Signaling Technology的抗MAPK和pMAPK抗体进行了免疫印迹实验。 更多
HLA G
major histocompatibility complex, class I, G
总数:1
HLA-G gene repression is reversed by demethylation. 2003 至该文献
HLA-A
major histocompatibility complex, class I, A
总数:8
Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice. 2008 至该文献
为了研究研究肿瘤和肿瘤基质细胞间的相互作用,采用了Santa Cruz Biotechnology HLA-A(A-18)抗体进行了免疫组化实验。 更多
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
总数:1
Expression of CD80 and CD86 costimulatory molecules are potential markers for better survival in nasopharyngeal carcinoma. 2007 至该文献
为了研究CD80和CD86可能作为鼻咽癌预后的标记物,采用Novocastra Laboratories的抗HLA Class II (DR)抗体进行免疫组织化学实验。
LTA
lymphotoxin alpha (TNF superfamily, member 1)
Toll样受体2 (TLR2)
toll-like receptor 2
总数:22
Inflammatory role of Toll-like receptors in human and murine adipose tissue. 2010 至该文献
为了研究人和鼠科脂肪组织中Toll样受体与网膜脂肪组织相关的炎症之间的关系,采用了Hycult Biotechnologies的单抗TLR2抗体进行ELISA实验。 更多
GSTM1
glutathione S-transferase mu 1
总数:2
14-3-3 interaction with histone H3 involves a dual modification pattern of phosphoacetylation. 2008 至该文献
为了研究因组蛋白H3乙酰化而激活的基因,采用Millipore的抗GST的抗体进行免疫印迹实验。 更多
人类白细胞抗原b (HLA B)
major histocompatibility complex, class I, B
总数:1
Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes. 2005 至该文献
TNF-alpha
tumor necrosis factor
总数:64
NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. 2008 至该文献
为了研究NFAT5在高渗压力下对人类角膜缘上皮细胞的作用,采用了R&D Systems的TNF-alpha抗体进行了蛋白质印迹实验。 更多
胰岛素 (insulin)
总数:22
Glucose and Weight Control in Mice with a Designed Ghrelin O-Acyltransferase Inhibitor.. 2010 至该文献
为了研究在已经设计好的grelin o-酰基转移酶抑制剂的小鼠体内体重和葡萄糖的控制,采用了Linco抗insulin抗体进行了免疫印迹实验。 更多
纤维母细胞生长因子受体2 (FGFR2)
fibroblast growth factor receptor 2
总数:9
Endothelial function of von Hippel-Lindau tumor suppressor gene: control of fibroblast growth factor receptor signaling. 2008 至该文献
为了研究VHL肿瘤抑制基因通过成纤维细胞生长因子受体信号通路对内皮功能的影响,采用了Santa Cruz的兔多抗FGFR2抗体进行免疫印迹实验。 更多
白细胞介素10 (IL-10)
interleukin 10
总数:20
Identification of IL-17-producing FOXP3+ regulatory T cells in humans. 2009 至该文献
为了确定IL-17+,FOXP3+调节性T细胞产生于外周血中,使用了R&D Systems公司的白介素10酶联免疫吸附试剂盒进行酶联免疫吸附实验。 更多
serotonin transporter
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
总数:7
Increased thalamocortical synaptic response and decreased layer IV innervation in GAP-43 knockout mice. 2007 至该文献
为研究神经生长相关蛋白 4 3(GAP 4 3) 在调控神经递质释放中的作用,采用Immunostar公司生产的5-羟色胺转运体(5-HTT)抗体用于免疫印迹和免疫组化实验。 更多
ICAM-1
intercellular adhesion molecule 1
总数:28
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy.. 2011 至该文献
为了研究在天然杀伤细胞免疫突触处皮质肌动蛋白的重塑,采用了R&D systems的抗ICAM-1抗体进行免疫细胞化学实验。 更多
IFN-gamma
interferon, gamma
总数:59
The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence.. 2011 至该文献
为了研究血脑屏障的完整性和中枢神经免疫沉默能够被Shh信号通路促进,采用R&D Systems的抗IFN-gamma抗体以5ug/ml浓度进行细胞刺激实验。 更多
CCR5
chemokine (C-C motif) receptor 5
总数:28
Effects of ferumoxides-protamine sulfate labeling on immunomodulatory characteristics of macrophage-like THP-1 cells. 2008 至该文献
Biolegend 荧光素共轭的鼠抗人 CD195 免疫球蛋白G2a用于流式细胞术来演示吞噬的FePro纳米粒不能显著的影响THP-1细胞的免疫特性。 更多
Cyp1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
总数:15
Potential therapeutic significance of increased expression of aryl hydrocarbon receptor in human gastric cancer. 2009 至该文献
为确定芳香烃受体在胃癌发生过程中的功能性意义,并探讨其在胃癌治疗中可能发挥的作用,将Chemicon International提供的抗CYP 1A1抗体(AB1258)用于蛋白免疫印迹实验中。 更多
HLA-C
major histocompatibility complex, class I, C
总数:7
Identification of major histocompatibility complex class I C molecule as an attachment factor that facilitates coronavirus HKU1 spike-mediated infection. 2009 至该文献
为了研究主要组织相容性复合体作为一种附属因子在促进 HCoV-HKU1 感染过程中的作用,采用英杰的纯化的羊免疫球蛋白作为同型标准品。 更多
血管紧张素转化酶 (ACE)
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
总数:8
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 至该文献
为了研究通过定量蛋白质组学发现新的BACE1底物,采用Santa Cruz的ACE抗体以1:1,000稀释进行蛋白印迹实验。 更多
Toll样受体4 (TLR4)
toll-like receptor 4
总数:36
Expression of Toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: upregulated expression of TLR2 in terminal ileum of patients with ulcerative colitis. 2008 至该文献
为了研究回肠粘膜中TLR2、TLR4和及其转膜辅助受体CD14的表达情况,采用Santa Cruz Biotechnology公司的羊抗TLR4多克隆抗体(1:10)进行免疫组织化学实验。 更多
白细胞介素6 (IL-6)
interleukin 6 (interferon, beta 2)
总数:41
Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes.. 2011 至该文献
为了研究具有分解代谢功能的细胞器和具有合成代谢功能的细胞器二者在空间上的结合在促进分泌蛋白合成中的作用,采用R&D systems的抗IL6抗体进行免疫细胞化学试验。 更多
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
总数:1
Regulation of human methylenetetrahydrofolate reductase by phosphorylation. 2005 至该文献