内质网
基因
试剂
文献样例
产品评述样例
转录激活因子6 (ATF6)
activating transcription factor 6
总数:4
Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy.. 2003 至该文献
Bip
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
总数:46
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. 2009 至该文献
为了研究知母皂甙AIII对肿瘤细胞造成细胞毒性的机制，使用了Santa Cruz公司的抗GRP78抗体来进行蛋白印迹分析。 更多
XBP1
X-box binding protein 1
总数:2
Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response. 2004 至该文献
Santa Cruz Biotechnologies的XBP1多克隆抗体被用于蛋白质印迹实验，来证明HCV抑制非折叠蛋白反应的IRE1-XBP1通路。 更多
ERN1
endoplasmic reticulum to nucleus signaling 1
总数:2
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. 2006 至该文献
Santa Cruz Biotechnology的抗IRE1α抗体被用于蛋白质印迹实验，来研究ER激活NF-κB的机制，以及在人的细胞中NF-κB在调节ER介导的细胞死亡中的作用。 更多
DERL1
Der1-like domain family, member 1
总数:2
Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation. 2009 至该文献
为了在内质网相关蛋白的降解途径（ERAD）中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能，使用了MBL International公司的抗体derlin-1来进行免疫印迹分析。 更多
SYVN1
synovial apoptosis inhibitor 1, synoviolin
总数:1
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD. 2008 至该文献
为了说明OS-9和XTP3-B/是内质网家族糖蛋白，和ERAD底物相连，通过SEL1L的转换，到达内质网膜镶嵌泛素连接Hrd1。采用了Abgent的Hrd1抗体进行免疫印迹试验。
DDIT3
DNA-damage-inducible transcript 3
总数:16
The eIF4E/eIF4G Interaction Inhibitor 4EGI-1 Augments TRAIL-Mediated Apoptosis through c-FLIP Down-regulation and DR5 Induction Independent of Inhibition of Cap-Dependent Protein Translation. 2010 至该文献
为了研究4EGI-1在TRAIL介导的细胞凋亡中的作用使用了Santa Cruz Biotechnology公司的鼠抗CHOP抗体来进行抑制或活化实验。 更多
STIM1
stromal interaction molecule 1
总数:4
Local Ca Entry Via Orai1 Regulates Plasma Membrane Recruitment of TRPC1 and Controls Cytosolic Ca Signals Required for Specific Cell Functions.. 2011 至该文献
为了研究通过orai1的局部钙离子输入导致的了trpc1招募到质膜上，并且能控制为某些特定的细胞功能所需的胞质内钙离子信号，采用了cell signaling 公司的抗stim1抗体进行western blot实验。 更多
OS9
osteosarcoma amplified 9, endoplasmic reticulum lectin
总数:1
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD. 2008 至该文献
为了说明OS-9和XTP3-B/是内质网家族糖蛋白，和ERAD底物相连，通过SEL1L的转换，到达内质网膜镶嵌泛素连接Hrd1。采用了Abcam的OS-9 抗体进行免疫印迹试验。
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
总数:1
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD. 2008 至该文献
为了说明OS-9和XTP3-B/是内质网家族糖蛋白，和ERAD底物相连，通过SEL1L的转换，到达内质网膜镶嵌泛素连接Hrd1。采用了Axxora的SEL1L抗体进行免疫印迹试验。
ERLEC1
endoplasmic reticulum lectin 1
VCP
valosin containing protein
总数:14
The differentiation/retrodifferentiation program of human U937 leukemia cells is accompanied by changes of VCP/p97. 2008 至该文献
为了研究VCP/p97在髓单核细胞分化和去分化中的作用，采用了Progen Biotechnik GmbH的抗VCP/p97抗体进行了免疫印迹实验。 更多
EDEM
ER degradation enhancer, mannosidase alpha-like 1
ATF4
activating transcription factor 4 (tax-responsive enhancer element B67)
总数:10
Selective Inhibition of a Regulatory Subunit of Protein Phosphatase 1 Restores Proteostasis.. 2011 至该文献
为了研究蛋白磷酸酶1的调控亚基能够被小分子选择性阻断，采用Santa Cruz的抗ATF4/CREB-2抗体以1/500浓度进行蛋白印迹实验。 更多
PERK
eukaryotic translation initiation factor 2-alpha kinase 3
总数:13
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 至该文献
为了说明Skp2参与非p19Arf-p53途径的细胞衰老，使用了Cell Signaling公司的Perk磷酸化抗体(Thr980)来进行免疫印记实验。 更多
RTN1
reticulon 1
AMFR
autocrine motility factor receptor
CASP4
caspase 4, apoptosis-related cysteine peptidase
总数:4
The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells. 2009 至该文献
为研究在培养细胞中淀粉样前蛋白的E693Δ突变对淀粉样蛋白β低聚物在胞内积聚现象的影响，以及其在促使内质网应激诱导的凋亡作用上所发挥的角色，将MBL提供的单克隆抗caspase-4抗体应用于蛋白免疫印迹实验中。 更多
ERO1L
ERO1-like (S. cerevisiae)
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
TMBIM6
transmembrane BAX inhibitor motif containing 6
MAN1B1
mannosidase, alpha, class 1B, member 1
ORAI1
ORAI calcium release-activated calcium modulator 1
TOR1A
torsin family 1, member A (torsin A)
总数:3
Overexpression of torsinA in PC12 cells protects against toxicity. 2004 至该文献
ERAP1
endoplasmic reticulum aminopeptidase 1
TXNDC12
thioredoxin domain containing 12 (endoplasmic reticulum)
UFD1L
ubiquitin fusion degradation 1 like (yeast)
总数:1
UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover. 2008 至该文献
为了研究UBXD7募集的p97在HIF1α降解的调节中的功能，使用了BD Transduction Laboratories公司的抗UFD1抗体来进行免疫印迹分析。
ERP29
endoplasmic reticulum protein 29
SELS
selenoprotein S
囊性纤维化跨膜电导调节因子 (CFTR)
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
总数:17
Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. 2009 至该文献
为了研究铜绿假单胞菌外膜囊泡对细菌致病基因的远程运输，使用了Upstate Biotechnology公司的CFTR鼠抗(clone M3A7)来进行免疫印记实验。 更多
ATL1
atlastin GTPase 1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
SFTPC
surfactant protein C
总数:2
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. 2010 至该文献
为了研究磷酸二酯酶6个亚基在特发性肺纤维化中的作用使用了Chemicon International 公司的抗PDE6D抗体（1:200稀释）来进行免疫组化实验。 更多
钙联接蛋白 (calnexin)
总数:73
Human Cytomegalovirus Directly Induces the Antiviral Protein Viperin to Enhance Infectivity.. 2011 至该文献
为了揭示蝰毒素如何促进感染，采用Abcam的抗calnexin抗体进行免疫细胞化学试验。 更多
SERCA2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
总数:10
Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2. 2007 至该文献
PRKCSH
protein kinase C substrate 80K-H
钙网蛋白 (calreticulin)
总数:39
An Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: the Wp/BHRF1 link. 2009 至该文献
为了研究BHRF1在调控病毒淋巴瘤生成中的作用，使用了Santa-Cruz Biotechnology公司的单克隆抗Calregulin抗体，进行了免疫印迹实验。 更多
ERAP2
endoplasmic reticulum aminopeptidase 2
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
UBQLN4
ubiquilin 4
RPN1
ribophorin I
oxygen regulated protein
hypoxia up-regulated 1
总数:1
Oxygen-regulated protein 150 and prognosis following myocardial infarction. 2007 至该文献
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
总数:2
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 至该文献
为了在内质网相关蛋白的降解途径（ERAD）中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能，使用了Abgent公司的抗体Herp来进行免疫印迹分析。 更多
RNF5
ring finger protein 5
WFS1
Wolfram syndrome 1 (wolframin)
SEC31A
SEC31 homolog A (S. cerevisiae)
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
FBXO11
F-box protein 11
总数:1
Genetic analysis of the subunit organization and function of the conserved oligomeric golgi (COG) complex: studies of COG5- and COG7-deficient mammalian cells. 2005 至该文献
SMAP 5
Yip1 domain family, member 5
PSEN2
presenilin 2 (Alzheimer disease 4)
总数:3
Neurotoxic mechanisms by Alzheimer's disease-linked N141I mutant presenilin 2. 2002 至该文献
PDI
protein disulfide isomerase family A, member 2
总数:18
Genome-wide screen of three herpesviruses for protein subcellular localization and alteration of PML nuclear bodies. 2008 至该文献
为了研究3种疱疹病毒编码的蛋白质的定位和功能，采用了AbCam公司的鼠抗PDI抗体进行免疫细胞化学实验。 更多
ATP2A3
ATPase, Ca++ transporting, ubiquitous
总数:3
Regulation of the nitric oxide pathway genes by tetrahydrofurandiols: microarray analysis of MCF-7 human breast cancer cells. 2008 至该文献
为了研究THF-diols在受一氧化氮调控通路基因中的作用，采用Santa Cruz生物技术公司ATP2A3抗体进行蛋白质印迹实验。 更多
ERp57
protein disulfide isomerase family A, member 3
总数:4
Endoplasmic reticulum chaperones stabilize nicotinic receptor subunits and regulate receptor assembly. 2007 至该文献
SEC16A
SEC16 homolog A (S. cerevisiae)
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
总数:5
Quantitative proteomic analysis by iTRAQ(R) for the identification of candidate biomarkers in ovarian cancer serum. 2010 至该文献
为研究通过iTRAQ®分析鉴定卵巢癌血清中的潜在生物标记，采用了Abcam公司的抗alpha-1 antitrypsin抗体进行蛋白质印迹试验。 更多
BCAP31
B-cell receptor-associated protein 31
总数:1
Endoplasmic reticulum membrane-sorting protein of lymphocytes (BAP31) is highly expressed in neurons and discrete endocrine cells. 2001 至该文献
PSMD2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
总数:1
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome. 2010 至该文献
为了说明hHR23A介导的Vpr与蛋白酶体的互作在病毒复制过程中有重要作用，使用了Calbiochem公司的19S蛋白酶体S2亚基的兔多抗来进行免疫印记实验。
SAR1A
SAR1 homolog A (S. cerevisiae)
prion protein
总数:17
No Evidence of Murine-Like Gammaretroviruses in CFS Patients Previously Identified as XMRV-Infected.. 2011 至该文献
为了研究慢性疲劳症候群病人未感染鼠gamma逆转录病毒，采用Chemicon的抗Prion Protein抗体进行PCR实验。 更多