内涵体
基因
试剂
文献样例
产品评述样例
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
Rab5
RAB5A, member RAS oncogene family
总数:19
Adenovirus RID-alpha activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C. 2009 至该文献
为了研究腺病毒膜蛋白RID-alpha诱导的胆固醇的转运途径,探究了RID-alpha激活胆固醇自我调节的机理,采用了BD公司RAS家族抗体,进行细胞免疫荧光实验。 更多
PDCD6IP
programmed cell death 6 interacting protein
总数:2
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. 2010 至该文献
为了揭示HOIP在CD40信号通路中的泛素连接酶功能,使用了Cell Signaling公司的ALIX抗体来进行免疫印记实验。 更多
NPC1
NPC intracellular cholesterol transporter 1
总数:2
MiR-33 contributes to the regulation of cholesterol homeostasis. 2010 至该文献
为了研究内含子区的miRNA miR-33在胆固醇代谢调节中的功能,使用了Novus公司的兔抗NPC1多克隆抗体来进行免疫印迹分析。 更多
Rab11
RAB11A, member RAS oncogene family
总数:9
Rab11b regulates the apical recycling of the cystic fibrosis transmembrane conductance regulator in polarized intestinal epithelial cells. 2009 至该文献
来自Invitrogen的兔源Rab11a多抗以1:500用于免疫印迹实验来研究Rab11蛋白在T84细胞中对CFTR运输的调控功能 更多
VPS35
VPS35 retromer complex component
总数:1
Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. 2007 至该文献
RAB7A
RAB7A, member RAS oncogene family
总数:5
Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. 2009 至该文献
为了研究铜绿假单胞菌外膜囊泡对细菌致病基因的远程运输,使用了Santa Cruz Biotechnology公司的Rab7兔抗来进行免疫印记实验。 更多
RABGEF1
RAB guanine nucleotide exchange factor 1
总数:2
Rabex-5 is a Rab22 effector and mediates a Rab22-Rab5 signaling cascade in endocytosis. 2009 至该文献
为了研究Rab22-CRabex-5-CRab5的串联在细胞内吞作用和表皮生长因子的降解中所起的关键作用,使用了BD Biosciences公司的抗Rabex-5抗体来进行蛋白印迹分析。 更多
TSG101
tumor susceptibility 101
总数:15
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 至该文献
为了研究ESCRT-III调控Aurora B介导的细胞脱落,采用了Abcam的单抗Tsg101抗体进行蛋白印迹实验。 更多
CHMP4A
charged multivesicular body protein 4A
总数:2
ESCRT-III governs the Aurora B-mediated abscission checkpoint through CHMP4C. 2012 至该文献
为了研究ESCRT-III调控Aurora B介导的细胞脱落,采用了Santa Cruz Biotechnology的抗CHMP4A抗体进行蛋白印迹实验。 更多
表皮生长因子受体 (EGFR)
epidermal growth factor receptor
总数:150
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway. 2013 至该文献
为了研究ING1a诱导细胞衰老的机制,使用圣克鲁斯生物技术公司的抗EGFR抗体,进行蛋白印迹试验。 更多
早期内涵体抗原1 (EEA1)
early endosome antigen 1
总数:78
Evolutionarily assembled cis-regulatory module at a human ciliopathy locus. 2012 至该文献
为了研究纤毛的形成受到进化过程中重组的顺式调控模块的调节,采用了Millipore的小鼠抗early endosome antigen1抗体进行免疫细胞化学实验。 更多
STAM
signal transducing adaptor molecule
总数:1
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 至该文献
为了说明arrestin-2/STAM-1复合体通过泛素化HRS调节CXCR4溶酶体分选,使用了ProteinTech Group公司的STAM-1多抗来进行免疫印记和免疫沉淀实验。
RAB9A
RAB9A, member RAS oncogene family
总数:5
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication. 2007 至该文献
为了研究Arf与脊髓灰质炎病毒蛋白3CD之间的相互作用及其对脊髓灰质炎病毒扩增的影响,使用了Affinity Bioreagents公司的抗Rab9抗体进行免疫印迹试验。 更多
EHD1
EH domain containing 1
总数:1
A role for EHD4 in the regulation of early endosomal transport. 2008 至该文献
为了研究EHD4在早期内体的转运调控中的功能,使用了AnaSpec公司的兔抗EHD1多克隆抗体来进行免疫印记分析和免疫沉淀实验。
VPS16
VPS16 core subunit of CORVET and HOPS complexes
UBC
ubiquitin C
总数:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 至该文献
为了研究突触的可塑性,采用了Enzo Life Sciences的抗Ubiquitin的抗体进行了免疫印迹实验。 更多
转铁蛋白受体 (transferrin receptor)
总数:70
UNC93B1 mediates differential trafficking of endosomal TLRs. 2013 至该文献
为了研究UNC93B1介导的内涵体Toll样受体不同的运输机制,采用eBiosciences公司的抗抗原递呈细胞CD71抗体进行流式细胞术试验。 更多
SNX1
sorting nexin 1
总数:8
Identification of novel proteins affected by rotenone in mitochondria of dopaminergic cells. 2007 至该文献
为了鉴定神经细胞中受鱼藤酮影响的新的线粒体蛋白,采用Proteintech公司的SNX1抗体,进行了蛋白质印迹实验。 更多
VAMP3
vesicle associated membrane protein 3
总数:4
Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3.. 2010 至该文献
为了研究接头蛋白3在Toll样受体9信号调控中的功能,使用了Synaptic Systems公司的兔抗VAMP3抗体来进行免疫荧光实验。 更多
VPS11
VPS11 core subunit of CORVET and HOPS complexes
EHD4
EH domain containing 4
总数:1
A role for EHD4 in the regulation of early endosomal transport. 2008 至该文献
为了研究EHD4在早期内体的转运调控中的功能,使用了AnaSpec公司的兔抗EHD4多克隆抗体来进行免疫印记分析和免疫沉淀实验。
VPS26A
VPS26, retromer complex component A
总数:1
Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. 2007 至该文献
OCRL
OCRL inositol polyphosphate-5-phosphatase
DNAJC13
DnaJ heat shock protein family (Hsp40) member C13
AMSH
STAM binding protein
总数:1
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 至该文献
为了说明arrestin-2/STAM-1复合体通过泛素化HRS调节CXCR4溶酶体分选,使用了ProteinTech Group公司的AMSH多抗来进行免疫印记实验。
VPS33A
VPS33A core subunit of CORVET and HOPS complexes
syntaxin 6
总数:7
The DnaJ-domain protein RME-8 functions in endosomal trafficking. 2005 至该文献
CIN85
SH3 domain containing kinase binding protein 1
IST1
IST1 factor associated with ESCRT-III
总数:1
Essential role of hIST1 in cytokinesis. 2009 至该文献
为了研究hIST1在胞质分裂中所起的重要作用,使用了ProteinTech Group公司的抗alpha-IST1抗体来进行蛋白印迹分析。
NHE5
solute carrier family 9 member A5
Toll样受体3 (TLR3)
toll like receptor 3
总数:9
Expression of Toll-like receptors in verruca and molluscum contagiosum. 2008 至该文献
为了在人体皮肤的冷冻切片上研究Toll样受体在疣和传染性软疣的表现,使用了Santa Cruz Biotechnology公司的羊多克隆的抗人体TLR3产品,进行了免疫组织化学实验。 更多
RAB4A
RAB4A, member RAS oncogene family
总数:8
Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. 2009 至该文献
为了研究铜绿假单胞菌外膜囊泡对细菌致病基因的远程运输,使用了Santa Cruz Biotechnology公司的Rab4兔抗来进行免疫印记实验。 更多
STX16
syntaxin 16
总数:1
Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins. 2007 至该文献
PIKFYVE
phosphoinositide kinase, FYVE-type zinc finger containing
VPS29
VPS29 retromer complex component
总数:1
Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. 2007 至该文献
AP1AR
adaptor related protein complex 1 associated regulatory protein
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
总数:1
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. 2009 至该文献
运用P. de Camilli 公司的抗PI4KII alpha 抗体,进行免疫印迹实验以揭示神经细胞和非神经细胞中赫曼斯基-普德拉克综合征蛋白复合体与磷脂酰肌醇4-激酶二型α的相互作用。
CBL
Cbl proto-oncogene
总数:13
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. 2008 至该文献
为了研究Lyn调节慢性粒细胞白血病细胞对imatinib敏感性的机制,使用了Cell Signaling Technology公司的抗酪氨酸磷酸化c-Cbl抗体来进行免疫印记分析。 更多
VPS4A
vacuolar protein sorting 4 homolog A
总数:1
Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. 2005 至该文献
STX7
syntaxin 7
总数:4
A VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels. 2009 至该文献
为了研究含有VAMP7和Vti1a的SNARE复合体在调控神经和非神经细胞表面交通通路中的作用,采用了Synaptic Systems公司兔多克隆syntaxin 7抗体产品,进行了免疫荧光实验。 更多
MYO6
myosin VI
总数:2
Myosin II co-chaperone general cell UNC-45 overexpression is associated with ovarian cancer, rapid proliferation, and motility. 2007 至该文献
为了研究UNC-45在调节肿瘤细胞增殖和转移中的功能,使用了Sigma公司的小鼠抗myosin VI抗体来进行免疫印迹分析。 更多
VTI1B
vesicle transport through interaction with t-SNAREs 1B
总数:1
Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia. 2005 至该文献
转铁蛋白 (transferrin)
总数:17
A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease. 2009 至该文献
为了阐明在帕金森症中,一个新的转铁蛋白/TfR2-介导的线粒体铁离子运输体系被阻断这样一个机制,采用了Stressgen公司的抗转铁蛋白抗体应用于免疫组化实验中。 更多