内皮细胞
基因
试剂
文献样例
产品评述样例
血管内皮生长因子 (VEGF)
vascular endothelial growth factor A
总数:76
Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib. 2008 至该文献
为了研究不间断给药伊立替康（irinotecan）对结肠直肠癌细胞的影响，采用了Oncogene Research Products公司的VEGF-A抗体进行免疫组化实验。 更多
eNOS
nitric oxide synthase 3 (endothelial cell)
总数:36
Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells. 2009 至该文献
为了研究purinergic在调控内皮细胞一氧化氮合成酶活性中的作用，采用了Upstate Laboratories公司的抗eNOS抗体产品，进行了免疫印迹实验。 更多
VEGFR-2
kinase insert domain receptor (a type III receptor tyrosine kinase)
总数:35
Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling. 2010 至该文献
为了研究Wnt信号途径中凝乳酶原受体和H+-ATPase介导的酸化所起的重要作用，使用了Santa Cruz公司的抗Flk-1抗体来进行免疫沉淀。 更多
VE cadherin
cadherin 5, type 2 (vascular endothelium)
总数:19
Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis. 2009 至该文献
为了阐明在人类多发性骨髓瘤中的血管发生可能由肿瘤产生多效蛋白发展而来，它能够诱导单核细胞转分化为血管内皮细胞，采用了eBioscience公司的抗CD144抗体，进行了免疫组织化学实验。 更多
ICAM-1
intercellular adhesion molecule 1
总数:28
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy.. 2011 至该文献
为了研究在天然杀伤细胞免疫突触处皮质肌动蛋白的重塑，采用了R&D systems的抗ICAM-1抗体进行免疫细胞化学实验。 更多
血管性血友病因子 (von Willebrand factor)
总数:32
Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells. 2009 至该文献
为研究Rab27a和MyRIP对内皮细胞释放的血管假性血友病因子的调节作用，使用了Serotec公司的羊源性VWF抗体检测假性血友病因子。 更多
VCAM-1
vascular cell adhesion molecule 1
总数:19
The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways. 2009 至该文献
为研究前列腺特异膜抗原在前列腺癌细胞的白介素6和CCL5的表达调控中所发挥的角色，将Immunotech提供的抗血管细胞粘附分子抗体用于阻断或激活实验中。 更多
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
总数:2
Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in endothelial cells by nitric oxide deficiency. 2004 至该文献
为了阐明不对称二甲基精氨酸的水平，采用了Sigma公司的鼠抗LOX-1的多克隆抗体进行蛋白质印迹分析 更多
tissue factor pathway inhibitor
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
总数:2
Versican G3 domain promotes blood coagulation through suppressing the activity of tissue factor pathway inhibitor-1. 2006 至该文献
E-selectin
selectin E
总数:5
The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor alpha expression in the synovium. 2008 至该文献
使用R & D 单克隆抗E选择蛋白抗体(BBIG-E4)进行免疫组织化学实验来研究是否类风湿关节炎肿瘤坏死因子(TNF)α封闭疗法产生的异质临床反应，可以用治疗开始之前滑膜(TNF)α的表达水平预测。 更多
内皮素1 (endothelin 1)
总数:9
Expression of endothelial nitric oxide synthase and endothelin-1 in skin tissue from amputated limbs of patients with complex regional pain syndrome. 2008 至该文献
为了检测eNOS和ET-1的分布与在切断四肢的CRPS病人的皮肤组织中通过由内皮标记CD31免疫反应代表的血管浓度有关，采用R&D systems鼠的抗人ET-1抗体(3G10)，进行免疫组织化学实验。 更多
tissue factor
coagulation factor III (thromboplastin, tissue factor)
总数:5
Versican G3 domain promotes blood coagulation through suppressing the activity of tissue factor pathway inhibitor-1. 2006 至该文献
CD31
platelet/endothelial cell adhesion molecule
总数:123
Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells. 2008 至该文献
为了研究Ras信号途径在专一指导血管内皮祖细胞中所起的作用，使用了eBioscience公司的抗PECAM1抗体来进行免疫组化分析。 更多
血管生成素2 (angiopoietin 2)
总数:5
Adrenocorticotropin preferentially up-regulates angiopoietin 2 in the human fetal adrenal gland: implications for coordinated adrenal organ growth and angiogenesis. 2006 至该文献
Santa Cruz生物技术公司的山羊抗人Ang2多克隆抗体应用于蛋白质印迹(1:400)和免疫细胞化学实验(1:40)中，来检测在HFA细胞中细胞生成素的表达，以及促肾上腺皮质激素对细胞生成素和其受体Tie2的调控。 更多
Flt-1
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
总数:16
The association of vascular endothelial growth factor receptor-1 with the risk of cancer progression following radical prostatectomy. 2008 至该文献
为证明VEGFRR-1的表达与根治性前列腺切除术后病人肿瘤的演进风险不具有相关性，采用R&D Systems的羊抗人VEGFR-1多克隆抗体（catalog number: AF321）进行免疫组织化学实验。 更多
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
总数:2
Elevation of activated protein C in synovial joints in rheumatoid arthritis and its correlation with matrix metalloproteinase 2. 2004 至该文献
FGF-2
fibroblast growth factor 2 (basic)
总数:19
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents. 2009 至该文献
为研究内皮衍生的成纤维生长因子2在人和啮齿类动物的肺动脉高压的进程中所发挥的作用，将Chemicon提供的兔多克隆抗纤维生长因子2抗体用于蛋白免疫印迹实验中。 更多
tie-2
TEK tyrosine kinase, endothelial
总数:11
Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis. 2009 至该文献
为了阐明在人类多发性骨髓瘤中的血管发生可能由肿瘤产生多效蛋白发展而来，它能够诱导单核细胞转分化为血管内皮细胞，采用了Santa Cruz Biotechnology公司的抗Flk-1抗体，进行了蛋白质印迹实验。 更多
血小板反应蛋白 (thrombospondin 1)
总数:22
Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling. 2009 至该文献
为了研究转化生长因子Beta信号在调控肿瘤生长中的作用，使用了Acbam公司的鼠单克隆抗人鼠thrombospondin-1抗体，进行了免疫组织化学实验。 更多
F2
coagulation factor II (thrombin)
总数:2
Identification of sequences within the gamma-carboxylase that represent a novel contact site with vitamin K-dependent proteins and that are required for activity. 2001 至该文献
DLL4
delta-like 4 (Drosophila)
总数:1
Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. 2007 至该文献
I. B. Lobov(Regeneron Pharmaceuticals)的Dll4抗体被用于免疫组织化学实验中，来研究Dll4蛋白在血管生长和分化中的作用。
PLAT
plasminogen activator, tissue
总数:2
Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling. 2008 至该文献
为了阐述锂抑制Smad3/4依赖性的转化生长因子-β-反应基因激活的机理，采用了Santa Cruz公司的tPA抗体进行了蛋白印迹实验。 更多
HIF-1 alpha
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
总数:62
Characterization of the Activation of Protein Tyrosine Phosphatase, Receptor-Type, Z Polypeptide 1 (PTPRZ1) by Hypoxia Inducible Factor-2 Alpha. 2010 至该文献
为了研究PTPRZ1启动子上HIF结合及Ets结合的基序并且说明了HIF-2可以激活PTPRZ1，使用了Novus Biologicals公司的HIF1alpha抗体进行染色质免疫沉淀实验。 更多
fractalkine
chemokine (C-X3-C motif) ligand 1
总数:1
Coexpression of fractalkine and its receptor in normal human endometrium and in endometrium from users of progestin-only contraception supports a role for fractalkine in leukocyte recruitment and endometrial remodeling. 2004 至该文献
ANGPT1
angiopoietin 1
总数:5
ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation. 2004 至该文献
为了研究ESE-1作为人的滑液软组织和骨中一个 Ang-1基因的新型的转录调节因子，采用Regeneron Pharmaceuticals公司的兔多克隆抗人的Ang-1抗体(L41309M)，进行免疫组织化学分析。 更多
PAR-1
coagulation factor II (thrombin) receptor
总数:7
Thrombin receptor expression is upregulated in prostate cancer. 2006 至该文献
为了估定前列腺癌中PAR1表现的情况，使用了Santa Cruz Biotechnology公司的鼠单克隆PAR1抗体，用1：2000进行了免疫印迹实验，用1：100进行了免疫组织化学实验。 更多
NOX4
NADPH oxidase 4
总数:2
Mutational analysis reveals distinct features of the Nox4-p22 phox complex. 2008 至该文献
为了研究p22phox关键性的调控亚基和Nox4之间的相互作用关系，采用了Santa Cruz Biotechnology公司的兔抗Nox4（7843）多克隆抗体进行免疫印迹和免疫细胞化学实验。 更多
KLF2
Kruppel-like factor 2 (lung)
总数:1
TRAF2 exerts its antiapoptotic effect by regulating the expression of Kr??ppel-like factor LKLF. 2003 至该文献
Jeffrey M. Leiden提供的肺 Kruppel样因子（LKLF) 抗体用于免疫印迹实验，来研究肿瘤坏死因子受体相关因子2(TRAF2) 在调控TNF诱导的细胞凋亡过程中的作用。
神经纤毛蛋白1 (neuropilin 1)
总数:7
Role of placenta growth factor in malignancy and evidence that an antagonistic PlGF/Flt-1 peptide inhibits the growth and metastasis of human breast cancer xenografts. 2007 至该文献
为研究胎盘生长因子（PlGF）在恶性肿瘤中的作用，采用Santa Cruz公司生产的神经纤毛蛋白-1(NRP-1)抗体用于免疫印迹和免疫组化实验。 更多
PROCR
protein C receptor, endothelial
总数:4
Endothelial protein C receptor is overexpressed in rheumatoid arthritic (RA) synovium and mediates the anti-inflammatory effects of activated protein C in RA monocytes. 2007 至该文献
为了确定与EPCR连接的主要细胞型，以及是否EPCR能调节激活蛋白C (APC)对这些细胞的影响，采用了R&D systems公司的羊抗人EPCR抗体进行免疫化学分析 更多
PAI-1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
总数:15
Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. 2010 至该文献
为了研究人纤溶酶原和钩端螺旋体内皮抑制素样蛋白A之间的相互作用，采用Novus Biologicals公司的山羊抗人纤溶酶原抗体进行酶联免疫吸附实验。 更多
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
总数:1
ADAMTS13 phenotype in plasma from normal individuals and patients with thrombotic thrombocytopenic purpura. 2007 至该文献
白细胞介素8 (IL-8)
interleukin 8
总数:46
Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes.. 2011 至该文献
为了研究具有分解代谢功能的细胞器和具有合成代谢功能的细胞器二者在空间上的结合在促进分泌蛋白合成中的作用，采用R&D systems的抗IL8抗体进行免疫细胞化学试验。 更多
Ras相关C3肉毒杆菌毒素底物1 (Rac1)
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
总数:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 至该文献
为研究RhoGDI2通过Rho GTPases抑制代谢的作用，采用了Millipore公司的抗Rac1单克隆抗体(1:1,000)进行免疫印迹试验。 更多
Vegfr-3
fms-related tyrosine kinase 4
总数:15
Expression of VEGF-C and its receptor VEGFR-3 in the bone marrow of patients with acute myeloid leukaemia. 2008 至该文献
为了研究急性髓性白血病人骨髓中VEGF-C和VEGFR-3的表达，采用了Santa Cruz的抗VEGFR-3(sc-321)抗体进行免疫组织化学试验。 更多
ADM2
adrenomedullin 2
Akt
v-akt murine thymoma viral oncogene homolog 1
总数:418
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H?-ATPase.. 2011 至该文献
为了研究泡状H+-ATPase参与到mTOR通路中mTORC1的转位和激活，采用Cell Signaling的抗Akt和抗S473磷酸化Akt抗体进行蛋白印迹实验。 更多
CRP
C-reactive protein, pentraxin-related
总数:13
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. 2009 至该文献
为研究有活性的gp130在炎症性肝细胞肿瘤中所发挥的作用，将Abcam提供的单克隆抗C反应蛋白抗体应用于免疫组织化学实验中。 更多
ACVRL1
activin A receptor type II-like 1
总数:4
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. 2008 至该文献
为了研究在人和鼠肺部发育晚期时TGF-beta信号的动态调节，采用了R&D Systems的羊抗Acvrl1(AF370)抗体进行免疫组织化学和免疫印迹试验。 更多
ESM1
endothelial cell-specific molecule 1
总数:1
A HEV-restricted sulfotransferase is expressed in rheumatoid arthritis synovium and is induced by lymphotoxin-alpha/beta and TNF-alpha in cultured endothelial cells.. 2005 至该文献
TCL
ras homolog gene family, member J
ECSCR
endothelial cell-specific chemotaxis regulator
PGF
placental growth factor
总数:3
A reproducible and quantifiable model of choroidal neovascularization induced by VEGF A165 after subretinal adenoviral gene transfer in the rabbit. 2008 至该文献
整合素αⅤ (integrin alpha v)
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
总数:22
Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength. 2009 至该文献
为了研究β3 integrin介导的vimentin中间纤维细胞表面募集的功能，使用了Chemicon公司的抗integrin alpha-V抗体来进行免疫荧光实验。 更多
netrin 4
血栓调节蛋白 (thrombomodulin)
总数:6
IL-32-dependent effects of IL-1beta on endothelial cell functions. 2009 至该文献
为研究IL-32在IL-1β对内皮细胞功能的影响过程中所发挥的作用，将R&Dsystems提供的不规则siRNA（沉默子阴性对照1）用于蛋白免疫印迹实验中。 更多
MCP-1
chemokine (C-C motif) ligand 2
总数:14
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 至该文献
为了研究单核细胞趋化蛋白1和CD40配基化对血管内皮生长因子产量的影响，采用了Santa Cruz公司的抗MCP-1抗体进行了免疫组织化学实验。 更多
HO-1
heme oxygenase (decycling) 1
总数:10
Protection against chromium (VI)-induced oxidative stress and apoptosis by Nrf2. Recruiting Nrf2 into the nucleus and disrupting the nuclear Nrf2/Keap1 association. 2007 至该文献
为了研究调停Cr的细胞反应的分子事件，使用了Santa Cruz Biotechnology 公司的HO-1抗体，进行了免疫印迹实验。 更多
ERK2
mitogen-activated protein kinase 1
总数:484
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 至该文献
为了研究在气喘患者中由TGFbeta和IL-10抑制造成的对T细胞的抗性的信号传导机制，采用了Santa Cruze Biotechnology的抗ERK1/2抗体和抗磷酸化ERK1/2抗体进行了免疫印迹检测，免疫组化实验和流式细胞检测。 更多
CXCL12
chemokine (C-X-C motif) ligand 12
总数:8
PTCH1 dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts. 2009 至该文献
为了研究痣样基底细胞癌综合征成纤维细胞中PTCH1+/−基因表型与基底细胞癌发生的相关性，采用了Abcam公司生产的兔抗人SDF1-alpha（又叫CXCL12）多克隆抗体用于免疫印迹实验。 更多