癫痫
基因
试剂
文献样例
产品评述样例
SCN1A
sodium voltage-gated channel alpha subunit 1
总数:4
Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy. 2006 至该文献
为了研究在SMEI Scn1a+/-杂合体中GABAergic抑制神经元里减少钠电流的作用,采用了Chemicon公司的抗NaV1.1抗体进行蛋白质印迹和免疫组织化学分析。 更多
SCN2A
sodium voltage-gated channel alpha subunit 2
总数:3
A role for myosin VI in the localization of axonal proteins. 2011 至该文献
为了研究肌球蛋白VI对轴突蛋白定位作用,采用了Neuromab公司的鼠源抗Nav1.2抗体,进行免疫细胞试验 更多
SCN3A
sodium voltage-gated channel alpha subunit 3
总数:1
Voltage-gated sodium channels in taste bud cells. 2009 至该文献
为了研究SCN2A, SCN3A 和SCN9A在调控味细胞动作电位中的作用,使用了Chemicon公司的兔多克隆抗SCN3A抗体,进行了免疫组织化学实验。
SYNGAP1
synaptic Ras GTPase activating protein 1
总数:3
Intracellular and trans-synaptic regulation of glutamatergic synaptogenesis by EphB receptors. 2006 至该文献
为了说明EphB2能控制特定种类的成熟谷氨酸突触的组成,采用了Affinity BioReagents公司的SynGAP抗体进行免疫组织化学分析。 更多
KCNQ2
potassium voltage-gated channel subfamily Q member 2
总数:2
Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons. 2006 至该文献
Chemicon的KCNQ2抗体被用于蛋白质印迹实验,来研究Kv7/KCNQ/M通道在控制细胞兴奋性中的作用。 更多
ATP结合转运蛋白B超家族成员1 (ABCB1)
ATP binding cassette subfamily B member 1
总数:15
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 至该文献
为了说明YB-1、GST、ABCB5和ERK3能够成为乳腺癌细胞耐药性治疗的潜在靶点,使用了Santa Cruz Biotechnology公司的MDR1抗体(1:500)来进行免疫印记实验。 更多
KCNQ3
potassium voltage-gated channel subfamily Q member 3
总数:1
Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons. 2006 至该文献
Chemicon的KCNQ3抗体被用于蛋白质印迹实验,来研究Kv7/KCNQ/M通道在控制细胞兴奋性中的作用。
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
总数:2
Cellular distribution and subcellular localization of molecular components of vesicular transmitter release in horizontal cells of rabbit retina. 2005 至该文献
Kir4.1 (Kir4.1)
potassium inwardly rectifying channel subfamily J member 10
总数:5
MLC1 is associated with the dystrophin-glycoprotein complex at astrocytic endfeet. 2007 至该文献
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
总数:3
Two molecular pathways (NMD and ERAD) contribute to a genetic epilepsy associated with the GABA(A) receptor GABRA1 PTC mutation, 975delC, S326fs328X. 2009 至该文献
为了研究GABAA受体α1突变致NMD和ERAD活性增强而导致的遗传性癫痫,采用了Chemicon公司生产的抗人GABAA受体α1单克隆抗体用于免疫印迹实验。 更多
CYP2C9
cytochrome P450 family 2 subfamily C member 9
总数:4
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 至该文献
MEF2C
myocyte enhancer factor 2C
总数:3
c-MYC independent nuclear reprogramming favors cardiogenic potential of induced pluripotent stem cells. 2010 至该文献
为了研究诱导多能干细胞的心脏潜能与核重新编程的关系,使用了proteintech公司的Mef2c兔抗(10056-1-AP; 1:50稀释)来进行免疫细胞化学实验。 更多
MRP2
ATP binding cassette subfamily C member 2
总数:7
ABCC2 (MRP2, cMOAT) can be localized in the nuclear membrane of ovarian carcinomas and correlates with resistance to cisplatin and clinical outcome. 2006 至该文献
UGT2B7
UDP glucuronosyltransferase family 2 member B7
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
总数:4
Recombinant addition of N-glycosylation sites to the basolateral Na,K-ATPase beta1 subunit results in its clustering in caveolae and apical sorting in HGT-1 cells. 2005 至该文献
TSC1
TSC complex subunit 1
总数:9
Thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor expression. 2010 至该文献
为了研究PC-1蛋白的羧基端如何增强TSC2和TSC1的相互作用从而抑制mTOR信号通路的机制,作者使用Zymed Laboratories公司的抗TSC1抗体进行免疫印迹和免疫沉淀实验。 更多
TSC2
TSC complex subunit 2
总数:26
Thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor expression. 2010 至该文献
为了研究PC-1蛋白的羧基端如何将TSC锚定在膜上从而抑制mTOR信号通路的机制,作者使用Epitomics公司的抗TSC2抗体进行免疫印迹和免疫沉淀实验。 更多
CACNA1A
calcium voltage-gated channel subunit alpha1 A
总数:1
Voltage-dependent calcium channels of dog basilar artery. 2007 至该文献
Alomone Laboratories的兔源Cav2.1多克隆抗体被用于蛋白质印迹实验,来研究依赖电压的钙离子通道的电生理学特性和分子特征。
GLUT1
solute carrier family 2 member 1
总数:23
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. 2009 至该文献
为了研究葡萄糖的缺少对KRAS信号途径发生突变所起的作用,使用了Abcam公司的兔源多克隆抗GLUT1抗体进行蛋白印迹试验。 更多
人类白细胞抗原b (HLA B)
major histocompatibility complex, class I, B
总数:1
Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes. 2005 至该文献
HERG
potassium voltage-gated channel subfamily H member 2
总数:6
Silencing of herg gene by shRNA inhibits SH-SY5Y cell growth in vitro and in vivo. 2008 至该文献
为了研究herg对于调节SH-SY5Y细胞生长和增殖的重要作用,采用了Santa Cruz公司的抗HERG(sc-15968,1:1000)抗体进行了免疫印记实验。 更多
BDNF
brain derived neurotrophic factor
总数:11
Differential expression of neurotrophins in postnatal C57BL/6 mice striatum. 2009 至该文献
在免疫组化实验中使用Chemicon International抗BDNF抗体,来证明新生C57BL/6小鼠脑皮层神经营养因子的表达差异。 更多
哺乳动物雷帕霉素靶蛋白 (mTOR)
mechanistic target of rapamycin kinase
总数:33
A gene signature-based approach identifies mTOR as a regulator of p73. 2008 至该文献
为了研究如何通过基于基因标签的方法检测mTOR是p73的一个调控因子,采用了Santa Cruz的多抗mTOR(N-19 (alpha-FRAP))抗体进行免疫印迹实验。 更多
IL-6 (IL-6)
interleukin 6
总数:43
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. 2012 至该文献
为了研究IL-26诱导促炎因子的分泌和促进Th17细胞的产生,采用了R&D Systems公司的抗IL-6抗体进行细胞刺激。 更多
基质金属蛋白酶-9 (MMP-9)
matrix metallopeptidase 9
总数:45
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 至该文献
为了研究蛋白激酶D1抑制乳腺肿瘤细胞侵袭的机制,采用了Epitomics公司的抗MMP-9抗体,进行了免疫组织化学实验。 更多
ApoE基因 (ApoE)
apolipoprotein E
总数:19
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 至该文献
为了研究高效肝炎C病毒颗粒的形成条件,采用了Calbiochem公司的抗ApoE抗体进行蛋白免疫印迹实验。 更多