脂肪肝

基因

试剂

文献样例

产品评述样例

PNPLA3
patatin like phospholipase domain containing 3

SREBP-1 (SREBP-1)
sterol regulatory element binding transcription factor 1

总数:11

Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells. 2009 至该文献

为了研究在骨骼肌细胞中β-连环蛋白信号的活化能够提高对胰岛素的敏感性的机制，采用了NeoMarkers公司的单克隆SREBP-1抗体，进行了蛋白质印记实验。更多

microsomal triglyceride transfer protein

GPT
glutamic--pyruvic transaminase

FGF21
fibroblast growth factor 21

MLXIPL
MLX interacting protein like

PPAR
peroxisome proliferator activated receptor alpha

总数:9

Integration of microRNA miR-122 in hepatic circadian gene expression. 2009 至该文献

为了研究综合microRNA mir-122在肝脏中的交替表达，采用Abcam公司兔多克隆抗体PPARβ/δ ，进行免疫沉淀实验。更多

RARRES2
retinoic acid receptor responder 2

磷脂酰乙醇胺-N-甲基转移酶 (phosphatidylethanolamine N methyltransferase)
phosphatidylethanolamine N-methyltransferase

脂联素 (adiponectin)
adiponectin, C1Q and collagen domain containing

总数:6

The mixed-lineage kinase DLK is a key regulator of 3T3-L1 adipocyte differentiation. 2009 至该文献

为了研究DLK在调控3T3-L1脂肪细胞分化中的作用，使用了Calbiochem公司的兔多克隆抗adiponectin抗体，进行了免疫印迹和沉淀实验。更多

PLIN2
perilipin 2

总数:2

Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 2010 至该文献

为了研究高效肝炎C病毒颗粒的形成条件，采用了Santa Cruz公司的抗ADRP抗体进行蛋白免疫印迹实验。更多

PPARgamma
peroxisome proliferator activated receptor gamma

总数:28

De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. 2009 至该文献

为了通过基因组范围筛查的方式发现在脂肪生成过程中的PPAR Gamma和RXR的结合位点，使用了Santa Cruz Biotechnology公司的抗PPAR gamma抗体来进行免疫印迹分析和染色质免疫沉淀实验。更多

AHSG
alpha 2-HS glycoprotein

总数:1

Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe. 2010 至该文献

为了研究非定向基于活性的蛋白解谱对识别活细胞中专一表达酶所起的作用，使用了R&D systems公司的抗fetuin A抗体来进行蛋白印迹分析。

IFNL3
interferon lambda 3

谷氨酰转肽酶 (glutamyl transpeptidase)
gamma-glutamyltransferase 1

美洲狮 (PUMA)
BCL2 binding component 3

总数:12

Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer. 2008 至该文献

为了研究结肠癌中一个有效的并特异的MDM2拮抗剂(MI-43)激活p53的机制和影响作用，采用了Calbiochem公司的抗PUMA抗体，进行了蛋白质印迹实验。更多

ADIPOR2
adiponectin receptor 2

细胞角蛋白18 (cytokeratin 18)
keratin 18

总数:23

A lack of premature termination codon read-through efficacy of PTC124 (Ataluren) in a diverse array of reporter assays. 2013 至该文献

为了研究PTC124药理学活性的作用机制，Abcam的抗角蛋白18抗体被用于进行蛋白质免疫印迹实验。更多

PPARGC1A
PPARG coactivator 1 alpha

总数:6

Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure. 2009 至该文献

为了研究Myc在介导肥厚型心肌病和心衰中的功能，使用了Santa Cruz Biotechnology公司的兔抗PGC-1α多克隆抗体来进行免疫组化实验。更多

visfatin
nicotinamide phosphoribosyltransferase

总数:1

Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. 2010 至该文献

为了研究DBC1在调控SIRT1的活性和高脂饮食诱发的小鼠脂肪肝中的作用，采用了Bethyl Laboratories公司的NAMPT抗体产品，进行了免疫印迹实验

SREBF2
sterol regulatory element binding transcription factor 2

总数:3

Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. 2005 至该文献

HFE
homeostatic iron regulator

RBP4
retinol binding protein 4

SERPINA12
serpin family A member 12

肥胖荷尔蒙受体 (leptin receptor)

总数:9

leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3. 2007 至该文献

KLF6
Kruppel like factor 6

总数:3

Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: effects of endothelin-1, oxidative stress and cytokines. 2008 至该文献

Santa Cruz生物技术公司生产的兔源性抗Klf6多克隆抗体用于探针硝化棉印迹技术，来研究Krǔppel样因子家族的转录因子表达在新生小鼠心肌细胞的不同调控机制。更多

IKK甲 (IKK alpha)
component of inhibitor of nuclear factor kappa B kinase complex

总数:49

Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 至该文献

为了研究切割的NIK 导致非经典的NF- kB 活性，采用了Santa Cruz Biotechnology的抗IKKα抗体进行免疫印迹实验。更多

HSD11B1
hydroxysteroid 11-beta dehydrogenase 1

总数:1

Quantitation and cellular localization of 11beta-HSD1 expression in murine thymus. 2006 至该文献