高尔基体
基因
试剂
文献样例
产品评述样例
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
总数:1
Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association. 2007 至该文献
GORASP1
golgi reassembly stacking protein 1, 65kDa
总数:1
Adenovirus-mediated gene transfer of mutated IkappaB kinase and IkappaBalpha reveal NF-kappaB-dependent as well as NF-kappaB-independent pathways of HAS1 activation. 2005 至该文献
GP73
golgi membrane protein 1
GORASP2
golgi reassembly stacking protein 2, 55kDa
总数:1
GRASP55 and GRASP65 play complementary and essential roles in Golgi cisternal stacking. 2010 至该文献
为阐明GRASP55和GRASP65在高尔基体扁平囊堆叠过程中的分子机理，采用了Proteintech公司的兔抗GRASP55多克隆抗体（货号：10598-1-AP, 37ug/150 ul）进行western免疫印迹实验和免疫细胞化学实验。
oxysterol binding protein
总数:1
Oxysterol binding protein induces upregulation of SREBP-1c and enhances hepatic lipogenesis. 2007 至该文献
RAB6A
RAB6A, member RAS oncogene family
总数:3
Cytoplasmic dynein participates in apically targeted stimulated secretory traffic in primary rabbit lacrimal acinar epithelial cells. 2003 至该文献
为了研究胞质动力蛋白参与碳酰胆碱激活泪腺腺泡上皮细胞中的初级兔根尖质膜，采用了Santa Cruz Biotechnology公司的兔多克隆抗体rab6抗体进行蛋白质印迹分析 更多
GM130
golgin A2
总数:60
Evolutionarily Assembled cis-Regulatory Module at a Human Ciliopathy Locus.. 2012 至该文献
为了研究纤毛的形成受到进化过程中重组的顺式调控模块的调节，采用了Abcam的小鼠抗GM130抗体进行免疫细胞化学实验。 更多
PAQR3
progestin and adipoQ receptor family member III
DYM
dymeclin
TMED2
transmembrane emp24 domain trafficking protein 2
SMAP 5
Yip1 domain family, member 5
p115
USO1 vesicle docking protein homolog (yeast)
总数:7
SPG3A protein atlastin-1 is enriched in growth cones and promotes axon elongation during neuronal development. 2006 至该文献
ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
TRIP11
thyroid hormone receptor interactor 11
SGMS1
sphingomyelin synthase 1
LMAN1
lectin, mannose-binding, 1
总数:5
Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. 2010 至该文献
为了研究在HCT116结肠直肠癌细胞中Bcl-2和Bcl-xL对自噬的调节作用，采用了Sigma公司的兔多克隆抗ERGIC-53抗体(1:1000)，进行了蛋白质印迹实验。 更多
AKAP9
A kinase (PRKA) anchor protein (yotiao) 9
总数:1
Transforming acidic coiled-coil-containing protein 4 interacts with centrosomal AKAP350 and the mitotic spindle apparatus. 2002 至该文献
CLN3
ceroid-lipofuscinosis, neuronal 3
总数:1
A dileucine motif and a cluster of acidic amino acids in the second cytoplasmic domain of the batten disease-related CLN3 protein are required for efficient lysosomal targeting. 2004 至该文献
ARF1
ADP-ribosylation factor 1
总数:8
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication. 2007 至该文献
为了研究Arf与脊髓灰质炎病毒蛋白3CD之间的相互作用及其对脊髓灰质炎病毒扩增的影响，使用了Affinity Bioreagents公司的抗Arf抗体进行免疫印迹试验。 更多
PRKD1
protein kinase D1
总数:15
Protein kinase C zeta. A novel regulator of both phosphorylation and de-phosphorylation of cardiac sarcomeric proteins. 2007 至该文献
为研究PKCζ对调节肌丝蛋白磷酸化和去磷酸化的作用，采用了Abgent公司的抗PKD抗体进行蛋白质印迹试验。 更多
MYO6
myosin VI
总数:3
Myosin II co-chaperone general cell UNC-45 overexpression is associated with ovarian cancer, rapid proliferation, and motility. 2007 至该文献
为了研究UNC-45在调节肿瘤细胞增殖和转移中的功能，使用了Sigma公司的小鼠抗myosin VI抗体来进行免疫印迹分析。 更多
optineurin
总数:3
Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth.. 2011 至该文献
为了研究沙门氏菌的生长被自噬受体optineurin的磷酸化限制，采用immunGlobe的抗磷酸化OPTN抗体进行蛋白印迹和免疫细胞化学实验。 更多
RAB1A
RAB1A, member RAS oncogene family
总数:1
A selective interaction between OS-9 and the carboxyl-terminal tail of meprin beta. 2002 至该文献
SORT1
sortilin 1
总数:3
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. 2005 至该文献
弗林蛋白酶 (furin)
furin (paired basic amino acid cleaving enzyme)
总数:7
Adenovirus RID-alpha activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C. 2009 至该文献
为了研究腺病毒膜蛋白RID-alpha诱导的胆固醇的转运途径，探究了RID-alpha激活胆固醇自我调节的机理，采用了Thermo Fisher Scientific公司弗林蛋白酶抗体，进行细胞免疫荧光实验。 更多
PCSK9
proprotein convertase subtilisin/kexin type 9
总数:2
Antibody-mediated disruption of the interaction between PCSK9 and the low-density lipoprotein receptor. 2009 至该文献
为阐明PCSK9特异性抗体可以逆转PCSK9介导的对细胞表面LDLRs的下调作用，采用了Abcam的羊抗人PCSK9多克隆抗体（catalog #:Ab28770）进行抗体阻断实验。 更多
cdc42
cell division cycle 42 (GTP binding protein, 25kDa)
总数:36
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation. 至该文献
为了研究肺部发炎部位slit2对嗜酸性粒细胞和嗜中性粒细胞的影响，采用了Santa Cruz Biotechnology公司的抗Cdc42抗体进行蛋白免疫印迹试验。 更多
BACE
beta-site APP-cleaving enzyme 1
总数:9
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 至该文献
为了研究通过定量蛋白质组学发现新的BACE1底物，采用Santa Cruz的BACE1抗体以1:1,000稀释进行蛋白印迹实验。 更多
HERG
potassium voltage-gated channel, subfamily H (eag-related), member 2
总数:6
Silencing of herg gene by shRNA inhibits SH-SY5Y cell growth in vitro and in vivo. 2008 至该文献
为了研究herg对于调节SH-SY5Y细胞生长和增殖的重要作用，采用了Santa Cruz公司的抗HERG(sc-15968,1:1000)抗体进行了免疫印记实验。 更多
Cx43
gap junction protein, alpha 1, 43kDa
总数:20
CD38 and CD157 ectoenzymes mark cell subsets in the human corneal limbus. 2009 至该文献
使用Santa Cruz 生物公司的的抗连接蛋白43抗体进行免疫组织化学实验来显示人类正常角膜有分子工具来激活代谢性NAD+，以维持角膜内环境稳定。 更多
α突触核蛋白 (alpha synuclein)
synuclein, alpha (non A4 component of amyloid precursor)
总数:33
Aggregates assembled from overexpression of wild-type alpha-synuclein are not toxic to human neuronal cells. 2008 至该文献
为了在体外建立一个路易体相关的神经退行性疾病的细胞模型，利用 Santa Cruz Biotechnology 公司抗突触蛋白特异性位点的抗体mAb211进行了蛋白质免疫印迹实验。 更多
ERK2
mitogen-activated protein kinase 1
总数:484
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 至该文献
为了研究在气喘患者中由TGFbeta和IL-10抑制造成的对T细胞的抗性的信号传导机制，采用了Santa Cruze Biotechnology的抗ERK1/2抗体和抗磷酸化ERK1/2抗体进行了免疫印迹检测，免疫组化实验和流式细胞检测。 更多
ERK1
mitogen-activated protein kinase 3
总数:249
Cyclin K and cyclin D1b are oncogenic in myeloma cells. 2010 至该文献
为了研究多发性骨髓瘤中细胞周期蛋白K和细胞周期蛋白D1b的作用，采用了Cell Signaling的抗p44/42 MAPK和抗磷酸化p44/42 MAPK (Thr202/Tyr204)抗体进行免疫印迹实验。 更多
表皮生长因子受体 (EGFR)
epidermal growth factor receptor
总数:147
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. 2010 至该文献
为了研究MMP-10和CTSF在糖尿病患者角膜伤口治愈不良中的作用，采用了Epitomics的抗磷酸化-EGFR(Tyr845)抗体进行免疫组化试验。 更多
UBC
ubiquitin C
总数:4
Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family. 2007 至该文献
为了研究人切片中PGRN的遗传变异性是否与其他的神经变性疾病有关，比如阿尔茨海默病（AD）或者帕金森病(PD)，采用了Dako公司的抗泛素的抗体进行免疫组织化学分析。 更多