肝细胞
基因
试剂
文献样例
产品评述样例
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
总数:10
Concurrent induction and mechanism-based inactivation of CYP3A4 by an L-valinamide derivative. 2003 至该文献
为了研究由L - VALINAMIDE衍生物并发诱导及机理为基础的CYP3A4的灭活，采用了Chemicon International公司的CYP3A4抗体进行蛋白质印迹分析。 更多
HNF4A
hepatocyte nuclear factor 4, alpha
总数:12
Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes. 2009 至该文献
为了研究PXR对CYP4F12的调控和对一系列启动子的共激活、共抑制作用，使用了Santa Cruz公司的抗HNF4 alpha抗体来进行ChIP分析。 更多
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
总数:7
Effects of avasimibe on cytochrome P450 2C9 expression in vitro and in vivo. 2004 至该文献
NR1I2
nuclear receptor subfamily 1, group I, member 2
总数:8
SIRT6 promotes DNA repair under stress by activating PARP1.. 2011 至该文献
为了研究氧化应激条件下DNA修复能被SIRT6通过PARP1活化加强，采用Calbiochem的兔多抗PAR抗体进行免疫沉淀实验。 更多
NR1H4
nuclear receptor subfamily 1, group H, member 4
总数:2
Tumor necrosis factor alpha-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis. 2003 至该文献
constitutive androstane receptor
nuclear receptor subfamily 1, group I, member 3
SR-BI
scavenger receptor class B, member 1
总数:11
miR-33 Contributes to the Regulation of Cholesterol Homeostasis.. 2010 至该文献
为了研究内含子区的miRNA miR-33在胆固醇代谢调节中的功能，使用了Novus公司的兔抗SR-B1多克隆抗体来进行免疫印迹分析。 更多
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
FGF19
fibroblast growth factor 19
总数:1
A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice. 2002 至该文献
HAMP
hepcidin antimicrobial peptide
ASGR1
asialoglycoprotein receptor 1
ASGR2
asialoglycoprotein receptor 2
总数:1
The Ashwell receptor mitigates the lethal coagulopathy of sepsis. 2008 至该文献
为了研究Ashwell受体对败血症致死凝血病的作用，采用了Abcam的抗ASGPR2抗体进行免疫组化实验。
FOXA2
forkhead box A2
总数:3
The forkhead box m1 transcription factor is essential for embryonic development of pulmonary vasculature. 2005 至该文献
claudin-1
claudin 1
总数:13
Protein kinase A-dependent step(s) in hepatitis C virus entry and infectivity. 2008 至该文献
为了研究蛋白激酶信号在丙型肝炎病毒感染的作用，采用了Novus公司的抗CLDN1抗体1C5-D9进行了免疫细胞化学实验。 更多
CYP1A2
cytochrome P450, family 1, subfamily A, polypeptide 2
总数:2
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 至该文献
ATP8B1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
HNF1A
HNF1 homeobox A
总数:10
Inherent sexually dimorphic expression of hepatic CYP2C12 correlated with repressed activation of growth hormone-regulated signal transduction in male rats. 2008 至该文献
使用Santa Cruz生物公司的抗HNF-4α抗体进行免疫印迹实验来证明持续的GH通过GHR激活Erk1和Erk2引起CYP2C12表达增加。 更多
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
总数:4
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 至该文献
PCSK9
proprotein convertase subtilisin/kexin type 9
总数:2
Antibody-mediated disruption of the interaction between PCSK9 and the low-density lipoprotein receptor. 2009 至该文献
为阐明PCSK9特异性抗体可以逆转PCSK9介导的对细胞表面LDLRs的下调作用，采用了Abcam的羊抗人PCSK9多克隆抗体（catalog #:Ab28770）进行抗体阻断实验。 更多
SREBP-1
sterol regulatory element binding transcription factor 1
总数:11
Activation of Wnt/beta-Catenin Signaling Increases Insulin Sensitivity through a Reciprocal Regulation of Wnt10b and SREBP-1c in Skeletal Muscle Cells. 2009 至该文献
为了研究在骨骼肌细胞中β-连环蛋白信号的活化能够提高对胰岛素的敏感性的机制，采用了NeoMarkers公司的单克隆SREBP-1抗体，进行了蛋白质印记实验。 更多
MRP2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
总数:7
Tumor necrosis factor alpha-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis. 2003 至该文献
MIR122
microRNA 122
AhR
aryl hydrocarbon receptor
总数:9
Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells.. 2010 至该文献
为了研究芳香烃受体拮抗剂StemRegenin 1促进人造血干细胞增殖的作用和机制，使用了Santa Cruz Biotechnology公司的抗AhR抗体来进行免疫印迹分析。 更多
CD81
CD81 molecule
总数:8
Fas death receptor enhances endocytic membrane traffic converging into the Golgi region. 2009 至该文献
为了研究内吞膜在高尔基体会聚的机制,使用了BD Biosciences的CD81做免疫细胞化学试验. 更多
弗林蛋白酶 (furin)
furin (paired basic amino acid cleaving enzyme)
总数:7
Adenovirus RID-alpha activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C. 2009 至该文献
为了研究腺病毒膜蛋白RID-alpha诱导的胆固醇的转运途径，探究了RID-alpha激活胆固醇自我调节的机理，采用了Thermo Fisher Scientific公司弗林蛋白酶抗体，进行细胞免疫荧光实验。 更多
SLCO1B3
solute carrier organic anion transporter family, member 1B3
总数:1
The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3. 2007 至该文献