Jurkat细胞
基因
试剂
文献样例
产品评述样例
Lck
lymphocyte-specific protein tyrosine kinase
总数:19
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 至该文献
ITK
IL2-inducible T-cell kinase
总数:7
Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation. 2009 至该文献
为了研究ITK在免疫缺陷综合征中的作用,采用了Epitomics公司的ITK (Y402)抗体进行蛋白印迹实验。 更多
SLP 76
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
总数:4
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.. 2011 至该文献
为了研究人造血系统细胞给以不同刺激的反应能通过单细胞多因子分选进行分析,采用BD Biosciences的抗SLP-76 (BLNK)(pY128)抗体以1ug/ml浓度进行细胞多因子分选实验。 更多
BCL10
B-cell CLL/lymphoma 10
总数:6
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation.. 2011 至该文献
为了研究切割的NIK 导致非经典的NF- kB 活性 ,采用了Santa Cruz Biotechnology的抗Bcl10抗体进行免疫印迹实验。 更多
LAT
linker for activation of T cells
总数:11
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 至该文献
IKKgamma
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
总数:20
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. 2010 至该文献
为了揭示HOIP在CD40信号通路中的泛素连接酶功能,使用了Santa Cruz Biotechnology公司的IKKc抗体(FL-419)来进行免疫印记实验。 更多
CARMA1
caspase recruitment domain family, member 11
总数:2
The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association. 2008 至该文献
为了阐明CARD11能够以一种信号可诱导的方式独立地募集信号转导辅因子,采用了Prosci公司的抗CARD11抗体,进行了蛋白质沉淀实验。 更多
PRKCQ
protein kinase C, theta
总数:10
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 至该文献
为了证明CCL2通过Rho/PKCalpha信号通道相互作用引起脑内皮的通透性过高,使用了Cell Signaling Technology公司的抗磷酸-PKC-theta抗体,进行了免疫印迹实验。 更多
ZAP 70
zeta-chain (TCR) associated protein kinase 70kDa
总数:19
Human ILT2 receptor associates with murine MHC class I molecules in vivo and impairs T cell function. 2006 至该文献
为了研究在活体内ILT2和鼠MHC I类分子的联系,在免疫印迹试验中使用了Upstate的ZAP-70抗体。 更多
MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
总数:4
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation.. 2011 至该文献
为了研究切割的NIK 导致非经典的NF- kB 活性 ,采用了Santa Cruz Biotechnology的抗NIK抗体进行免疫印迹实验。 更多
肿瘤坏死因子受体超家族成员6 (Fas)
Fas (TNF receptor superfamily, member 6)
总数:52
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 至该文献
为了说明YB-1、GST、ABCB5和ERK3能够成为乳腺癌细胞耐药性治疗的潜在靶点,使用了Santa Cruz Biotechnology公司的FAS抗体(1:500)来进行免疫印记实验。 更多
白细胞介素2 (interleukin 2)
总数:15
Identification of IL-17-producing FOXP3+ regulatory T cells in humans. 2009 至该文献
为了确定IL-17+,FOXP3+调节性T细胞产生于外周血中,使用了R&D Systems公司的白介素2酶联免疫吸附试剂盒进行酶联免疫吸附实验。 更多
Vav
vav 1 guanine nucleotide exchange factor
总数:13
Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15. 2009 至该文献
为了研究胞液PLA2在细胞毒性T淋巴细胞介导的乳糜泻免疫病理学中的作用,采用了Cell Signaling Technology的抗Vav1抗体进行免疫沉淀反应实验。 更多
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
总数:1
Transformation of the proteasome with age-related macular degeneration. 2007 至该文献
为了研究在年龄相关的斑点降解(AMD)疾病过程中蛋白酶体是如何变化的,采用了Affinity Bioreagents公司的蛋白酶体亚基β5抗体,进行了蛋白质印迹实验.
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
总数:4
TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice. 2010 至该文献
为了了研究TLR4在调控TCR活化和小鼠实验性大肠炎中的作用,采用了Abcam公司的NFAT1抗体产品,进行了免疫印迹实验。 更多
Bcl 2
B-cell CLL/lymphoma 2
总数:128
miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. 2008 至该文献
为了研究SGC7901/VCR细胞中miR-15b和miR-16对BCL2蛋白表达的影响,采用了Santa Cruz Biotechnology公司的BCL2抗体进行免疫印迹实验。 更多
Caspase-9
caspase 9, apoptosis-related cysteine peptidase
总数:74
Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis. 2008 至该文献
为了评价Ginsenoside Rk1蛋白对细胞和端粒酶活性的影响,使用了Cell Signaling Technology公司的抗caspase-9抗体来进行蛋白印迹实验。 更多
TAL1
T-cell acute lymphocytic leukemia 1
总数:3
Tal1/SCL binding to pericentromeric DNA represses transcription. 2005 至该文献
TRAIL
tumor necrosis factor (ligand) superfamily, member 10
总数:6
Small interference RNA-mediated gene silencing of human biliverdin reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells. 2005 至该文献
caspase-8
caspase 8, apoptosis-related cysteine peptidase
总数:73
Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity. 2009 至该文献
为了研究SARS冠状病毒激活PKR和PERK并且克服eIF2α对病毒mRNA翻译的抑制作用的机制,使用了Cell Signaling公司的小鼠抗casp8单克隆抗体来进行免疫印迹分析。 更多
NF-E2相关因子2 (Nrf2)
GA binding protein transcription factor, alpha subunit 60kDa
总数:5
Nuclear import and export signals in control of Nrf2. 2005 至该文献
CD28
CD28 molecule
总数:23
Binding of superantigen toxins into the CD28 homodimer interface is essential for induction of cytokine genes that mediate lethal shock.. 2011 至该文献
为了研究毒素类和CD28异二聚体的结合诱导细胞因子,采用了R&D Systems的抗CD28抗体进行免疫印迹实验。 更多
caspase-3
caspase 3, apoptosis-related cysteine peptidase
总数:209
A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis.. 2011 至该文献
为了研究myc依赖的癌症需要SUMO化修饰来促进肿瘤发生,采用Cell Signaling的抗Cleaved caspase-3抗体进行蛋白印迹实验。 更多
FasL
Fas ligand (TNF superfamily, member 6)
总数:12
HYAL1-v1, an alternatively spliced variant of HYAL1 hyaluronidase: a negative regulator of bladder cancer. 2006 至该文献
BY55
CD160 molecule
总数:1
A novel activity for substance P: stimulation of peroxisome proliferator-activated receptor-gamma protein expression in human monocytes and macrophages. 2008 至该文献
TRA@
T cell receptor alpha locus
总数:9
Itk Derived Signals Regulate the Expression of Th-POK and Controls the Development of CD4 T Cells. 2010 至该文献
为了研究Itk在CD4/CD8定型中的调控作用,使用了BD Pharmingen公司的抗V alpha2抗体,进行了流式细胞测定实验。 更多
IKZF1
IKAROS family zinc finger 1 (Ikaros)
总数:1
Roles of USF, Ikaros and Sp proteins in the transcriptional regulation of the human reduced folate carrier B promoter. 2004 至该文献
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
总数:4
Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis. 2009 至该文献
为了推断钙调磷酸酶活性和白血病细胞凋亡能够通过糖皮质激素介导上调的RCAN1-1来调节,使用了Sigma-Aldrich公司的抗体calcineurin A来进行免疫印迹分析。 更多
趋化因子受体4 (CXCR4)
chemokine (C-X-C motif) receptor 4
总数:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.. 2011 至该文献
为了研究人造血系统细胞给以不同刺激的反应能通过单细胞多因子分选进行分析,采用Biolegend的抗CXCR4抗体以3ug/ml浓度进行细胞多因子分选实验。 更多
Kv1.3
potassium voltage-gated channel, shaker-related subfamily, member 3
总数:6
Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1. 2008 至该文献
为了研究IκB激酶β的γ结构域的磷酸化作用使用了Sigma 公司的FLAG抗体(1:1000稀释)来进行蛋白印迹实验。 更多
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
caspase-7
caspase 7, apoptosis-related cysteine peptidase
总数:23
NKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease. 至该文献
为了说明多个依赖于CD3 Zeta的受体可以同时因病变的NKG2D配体表达而损伤,使用了Cell Signaling Technology公司的抗caspase-7抗体进行蛋白印迹实验。 更多
p50
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
总数:80
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 至该文献
为了说明流感病毒感染期间IL-32表达水平的提高抑制病毒的复制,使用了Santa Cruz Biotechnology公司的anti-p50抗体来进行染色质免疫共沉淀实验。 更多
ICBP90
ubiquitin-like with PHD and ring finger domains 1
c-Jun
jun proto-oncogene
总数:102
Gene regulation of CYP4F11 in human keratinocyte HaCaT cells. 2010 至该文献
为了说明在人角质形成细胞HaCaT中,维甲酸能够通过多条信号通路包括RXR和JNK通路来抑制CYP4F11的表达,使用了Cell Signaling Technology公司的c-Jun单抗来进行免疫印记实验。 更多
LFA-1
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
总数:13
CXCL12-induced partitioning of flotillin-1 with lipid rafts plays a role in CXCR4 function. 2007 至该文献
IKK alpha
conserved helix-loop-helix ubiquitous kinase
总数:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation.. 2011 至该文献
为了研究切割的NIK 导致非经典的NF- kB 活性 ,采用了Santa Cruz Biotechnology的抗IKKα抗体进行免疫印迹实验。 更多
DR5
tumor necrosis factor receptor superfamily, member 10b
总数:15
The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease. 2010 至该文献
为了研究Fas配体和TRAIL在调控鼠胸腺移植物抗宿主病中的作用,采用了eBioscience公司的抗DR5抗体产品,进行了流式细胞分析实验。 更多
radixin
总数:4
Participation of ezrin in bacterial uptake by trophoblast giant cells. 2009 至该文献
为了研究埃兹蛋白在细菌通过滋养层巨细胞入侵的过程中所起的作用,使用了EPITOMICS公司的抗根蛋白抗体来进行蛋白印迹分析。 更多
CD247
CD247 molecule
总数:64
The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence.. 2011 至该文献
为了研究血脑屏障的完整性和中枢神经免疫沉默能够被Shh信号通路促进,采用eBioscience的抗CD3抗体以2.5ug/ml浓度进行细胞刺激实验。 更多
PANX1
pannexin 1
总数:1
Pannexin1 is expressed by neurons and glia but does not form functional gap junctions. 2007 至该文献
CXCL12
chemokine (C-X-C motif) ligand 12
总数:8
PTCH1 dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts. 2009 至该文献
为了研究痣样基底细胞癌综合征成纤维细胞中PTCH1+/−基因表型与基底细胞癌发生的相关性,采用了Abcam公司生产的兔抗人SDF1-alpha(又叫CXCL12)多克隆抗体用于免疫印迹实验。 更多
钙网蛋白 (calreticulin)
总数:39
An Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: the Wp/BHRF1 link. 2009 至该文献
为了研究BHRF1在调控病毒淋巴瘤生成中的作用,使用了Santa-Cruz Biotechnology公司的单克隆抗Calregulin抗体,进行了免疫印迹实验。 更多
AML1
runt-related transcription factor 1
总数:3
RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis. 2008 至该文献
Sigma公司生产的抗RUNX1多克隆抗体(兔)可用于免疫细胞化学实验,来研究E4orf6、E1B-55K及 RUNX1间的相互作用,以及RUNX1与病毒DNA?RNA核心的联系。 更多
RIP
receptor (TNFRSF)-interacting serine-threonine kinase 1
总数:9
Repression of NF-kappaB and activation of AP-1 enhance apoptosis in prostate cancer cells. 2009 至该文献
为研究NF-κB的抑制和AP-1的激活对前列腺癌细胞凋亡的影响,将Santa Cruz提供的抗RIP抗体用于蛋白免疫印迹实验中。 更多
CTSK
cathepsin K
总数:2
Characterization of osteoclasts from patients harboring a G215R mutation in ClC-7 causing autosomal dominant osteopetrosis type II. 2004 至该文献
TRB@
T cell receptor beta locus
总数:7
Potential roles of a special CD8 alpha alpha+ cell population and CC chemokine thymus-expressed chemokine in ovulation related inflammation. 2009 至该文献
为了研究卵巢CD8αα+细胞和CC趋化因子TECK对于排卵作用引起的炎症的作用,在流式细胞术中使用了BD Bio Sciences公司的TcRβ抗体。 更多
IKKbeta
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
总数:32
Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation. 2009 至该文献
为了研究TRAF2对应激诱导的细胞死亡的抑制机制,采用了Santa Cruz的抗IKKbeta抗体进行免疫印迹实验 更多
Bid
BH3 interacting domain death agonist
总数:35
Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy.. 2011 至该文献
为了研究化疗对线粒体激发高的病人有着良好的治疗效果,采用Santa Cruz的抗Bid抗体进行蛋白印迹实验。 更多
moesin
总数:10
Participation of ezrin in bacterial uptake by trophoblast giant cells. 2009 至该文献
为了研究埃兹蛋白在细菌通过滋养层巨细胞入侵的过程中所起的作用,使用了EPITOMICS公司的抗膜突蛋白抗体来进行蛋白印迹分析。 更多
BRG1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
总数:13
Repressive LTR Nucleosome Positioning by the BAF Complex Is Required for HIV Latency.. 2011 至该文献
为了研究SWI/SNF在潜伏期HIV LTR转录激活前后的调节作用,采用了Abcam SMARCB4进行了蛋白质免疫印迹实验。 更多
MYB
v-myb myeloblastosis viral oncogene homolog (avian)
总数:7
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. 2010 至该文献
为了阐明c-Myb在MLL相关白血病中的作用,实验使用了Upstate Biotechnology公司的抗c-Myb抗体进行免疫共沉淀。 更多
JNK
mitogen-activated protein kinase 8
总数:190
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. 2010 至该文献
为研究如何通过两阶段MAPK反应区分上皮细胞盾壳菌的酵母和菌丝形态,采用了Cell Signaling Technologies公司的抗磷酸化JNK抗体进行蛋白质印迹试验。 更多
Akt
v-akt murine thymoma viral oncogene homolog 1
总数:418
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H?-ATPase.. 2011 至该文献
为了研究泡状H+-ATPase参与到mTOR通路中mTORC1的转位和激活,采用Cell Signaling的抗Akt和抗S473磷酸化Akt抗体进行蛋白印迹实验。 更多
CTCF
CCCTC-binding factor (zinc finger protein)
总数:10
Parp1 localizes within the Dnmt1 promoter and protects its unmethylated state by its enzymatic activity. 2009 至该文献
为了说明Parp1基因和ADP核糖多聚体位于Dnmt1启动子上和说明Parp1能够保护自己的非甲基化状态,使用了Upstate公司抗Ctcf兔多克隆抗体来进行蛋白印迹实验。 更多
PYK2
PTK2B protein tyrosine kinase 2 beta
总数:27
SOCS3 inhibiting migration of A549 cells correlates with PYK2 signaling in vitro. 2008 至该文献
为了研究SOCS3同肺癌侵润性的关系, 采用了Santa Cruz公司的兔多克隆抗PYK2抗体,进行了蛋白印记实验。 更多
ORAI1
ORAI calcium release-activated calcium modulator 1
CTLA 4
cytotoxic T-lymphocyte-associated protein 4
总数:5
Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell Extrinsic Function of CTLA-4.. 2011 至该文献
为了揭示CTLA-4为何能够抑制CD28的激活,采用Santa Cruz的抗CTLA-4抗体进行免疫细胞化学试验。 更多
Mcl-1
myeloid cell leukemia sequence 1 (BCL2-related)
总数:31
Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy.. 2011 至该文献
为了研究化疗对线粒体激发高的病人有着良好的治疗效果,采用Santa Cruz的抗MCL-1抗体进行蛋白印迹实验。 更多
CBP
CREB binding protein
总数:38
Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation. 2009 至该文献
Santa Cruz Biotechnology CBP 抗体用于免疫印记来研究MSK1在调控NF-κB活性和发炎性疾病中的作用 更多
CD45
protein tyrosine phosphatase, receptor type, C
总数:120
Live Attenuated Malaria Vaccine Designed to Protect through Hepatic CD8+ T Cell Immunity.. 2011 至该文献
为了研究减毒活疫苗能够激活恶性疟原虫孢子特特异的CD8+免疫细胞而激活免疫反应,采用Beckman Coulter的抗CD45RA抗体进行流式细胞分选实验。 更多
PARP
poly (ADP-ribose) polymerase 1
总数:175
SIRT6 promotes DNA repair under stress by activating PARP1.. 2011 至该文献
为了研究氧化应激条件下DNA修复能被SIRT6通过PARP1活化加强,采用Abcam的抗PARP1抗体进行蛋白印迹实验。 更多
CD18
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
总数:21
CBF{beta} is critical for AML1-ETO and TEL-AML1 activity. 2009 至该文献
Tak1
mitogen-activated protein kinase kinase kinase 7
总数:9
TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation. 2005 至该文献
IFN-gamma
interferon, gamma
总数:59
The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence.. 2011 至该文献
为了研究血脑屏障的完整性和中枢神经免疫沉默能够被Shh信号通路促进,采用R&D Systems的抗IFN-gamma抗体以5ug/ml浓度进行细胞刺激实验。 更多
CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence
总数:12
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. 2008 至该文献
为了研究Lyn调节慢性粒细胞白血病细胞对imatinib敏感性的机制,使用了Cell Signaling Technology公司的抗酪氨酸磷酸化c-Cbl抗体来进行免疫印记分析。 更多
ezrin
总数:26
Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles. 2009 至该文献
为了研究铜绿假单胞菌外膜囊泡对细菌致病基因的远程运输,使用了BD Biosciences公司的ezrin鼠抗来进行免疫印记实验。 更多
Ras相关C3肉毒杆菌毒素底物1 (Rac1)
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
总数:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 至该文献
为研究RhoGDI2通过Rho GTPases抑制代谢的作用,采用了Millipore公司的抗Rac1单克隆抗体(1:1,000)进行免疫印迹试验。 更多
KIR3DL1
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
BST2
bone marrow stromal cell antigen 2
总数:1
A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells. 2009 至该文献
B细胞淋巴瘤2相关的X蛋白 (Bax)
BCL2-associated X protein
总数:102
Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy.. 2011 至该文献
为了研究化疗对线粒体激发高的病人有着良好的治疗效果,采用Santa Cruz的抗BAX抗体进行蛋白印迹实验。 更多
ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
总数:7
Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells. 2009 至该文献
为了研究MuPAR和纤溶酶在调控HSPCs和HSCs增殖,骨髓池大小,寻靶,移植物移入及活动中的作用,使用了eBioscience公司的抗alpha4beta1抗体,进行了免疫组织化学实验。 更多
HuR
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
总数:13
Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43. 2010 至该文献
为了描述TAR DNA-结合蛋白-43的选择性同源异构体和包涵体,采用了Santa Cruz Biotechnology的鼠单克隆抗HuR抗体(3A2,1:1000)进行免疫印迹试验。 更多
Skp2
S-phase kinase-associated protein 2 (p45)
总数:17
Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy. 2009 至该文献
为了在K562细胞中研究CSN对细胞自噬有重要作用,采用Zymed的抗Skp2抗体以1:1000稀释进行蛋白印迹实验。 更多
PDCD1
programmed cell death 1
总数:1
FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy. 2008 至该文献
TGF-beta1
transforming growth factor, beta 1
总数:33
Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 至该文献
为研究CD147促使成肌纤维细胞分化在组织变构中的作用,采用了R&D Systems公司的抗pan-TGFβ抗体进行抑制试验。 更多
白细胞介素4 (IL-4)
interleukin 4
总数:18
The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence.. 2011 至该文献
为了研究血脑屏障的完整性和中枢神经免疫沉默能够被Shh信号通路促进,采用R&D Systems的抗IL-4抗体以5ug/ml浓度进行细胞刺激实验。 更多
HDAC1
histone deacetylase 1
总数:51
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 至该文献
为了说明IRF5同HATs和HDACs一起调控促炎细胞因子的转录水平表达,使用了Upstate Biotechnology公司的抗HDAC1抗体进行蛋白印迹实验。 更多
abl
c-abl oncogene 1, non-receptor tyrosine kinase
总数:33
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 至该文献
为了研究c-Abl酪氨酸激酶在调控心脏的生长和发育中的作用,采用了Calbiochem公司的c-Abl 抗体产品( 1:1,000 ),进行了免疫印迹实验 更多
Bak
BCL2-antagonist/killer 1
总数:26
Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy.. 2011 至该文献
为了研究化疗对线粒体激发高的病人有着良好的治疗效果,采用Upstate的抗BAK抗体进行蛋白印迹实验。 更多
UBC
ubiquitin C
总数:4
Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family. 2007 至该文献
为了研究人切片中PGRN的遗传变异性是否与其他的神经变性疾病有关,比如阿尔茨海默病(AD)或者帕金森病(PD),采用了Dako公司的抗泛素的抗体进行免疫组织化学分析。 更多
CD274
CD274 molecule
总数:5
A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages. 2009 至该文献
为了研究JAK-STAT1通道在调控HSV-1复制中的作用,使用了Biolegend公司的抗B7-H1抗体,来收集和染色受感染的细胞,进行了流式细胞计量实验。 更多
Dnmt1
DNA (cytosine-5-)-methyltransferase 1
总数:13
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 至该文献
为了说明流感病毒感染期间IL-32表达水平的提高抑制病毒的复制,使用了Santa Cruz Biotechnology公司的anti-DNMT1抗体来进行染色质免疫共沉淀实验。 更多
NPM1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
总数:11
Cytoplasmic p53 and Activated Bax Regulate p53-dependent, Transcription-independent Neural Precursor Cell Apoptosis. 2010 至该文献
为了研究活化的Bax在调控依赖p53而非其转录活性依赖的神经祖细胞凋亡中的作用,采用了Zymed公司的抗NPM抗体产品,进行了免疫印迹实验。 更多
磷酸酶张力蛋白同源基因 (PTEN)
phosphatase and tensin homolog
总数:45
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 至该文献
为了说明Skp2参与非p19Arf-p53途径的细胞衰老,使用了Neomarkers公司的PTEN抗体来进行免疫组化实验。 更多
锰超氧化物歧化酶 (manganese superoxide dismutase)
superoxide dismutase 2, mitochondrial
总数:8
CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells. 2008 至该文献
为了研究CD30信号在霍奇金细胞系和间变性大细胞淋巴瘤(ALCL)细胞系中的重要作用,采用了Upstate Biotechnology的抗MnSOD抗体进行免疫印迹试验。 更多
ADAM金属肽酶成员17 (ADAM17)
ADAM metallopeptidase domain 17
总数:13
TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. 2008 至该文献
为了证明TACE在结肠直肠癌细胞中可以抑制EGFR通路,采用了Santa Cruz Biotechnology的抗TACE抗体进行了免疫印迹实验。 更多
p65
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
总数:143
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 至该文献
为了说明流感病毒感染期间IL-32表达水平的提高抑制病毒的复制,使用了Santa Cruz Biotechnology公司的anti-p65抗体来进行染色质免疫共沉淀实验。 更多
ERK2
mitogen-activated protein kinase 1
总数:484
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. 至该文献
为了研究在气喘患者中由TGFbeta和IL-10抑制造成的对T细胞的抗性的信号传导机制,采用了Santa Cruze Biotechnology的抗ERK1/2抗体和抗磷酸化ERK1/2抗体进行了免疫印迹检测,免疫组化实验和流式细胞检测。 更多