肾脏疾病
基因
试剂
文献样例
产品评述样例
cystatin C
总数:2
Cysteine protease cathepsin F is expressed in human atherosclerotic lesions, is secreted by cultured macrophages, and modifies low density lipoprotein particles in vitro. 2004 至该文献
FGF23
fibroblast growth factor 23
CLCN5
chloride channel 5
总数:2
Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells. 2004 至该文献
为研究Nedd4-2与氯离子通道ClC-5相互作用在肾近段小管白蛋白包吞过程中的作用，采用Antibody 的ClC-5抗体用于免疫沉淀实验。 更多
LCN2
lipocalin 2
总数:5
Lipocalin 2 promotes breast cancer progression. 2009 至该文献
为研究Lipocalin2蛋白对乳腺癌发展的影响，将R&D Systems提供的抗人Lcn2抗体用于免疫组织化学实验中。 更多
UMOD
uromodulin
总数:4
Localization of broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney. 2007 至该文献
FABP1
fatty acid binding protein 1, liver
总数:3
Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury. 2010 至该文献
为研究L-FABP蛋白在急性肾损伤(AKI)中的预后作用，采用了R&D Systems公司的羊抗人L-FABP多克隆抗体进行蛋白质印迹试验。 更多
MYH9
myosin, heavy chain 9, non-muscle
总数:3
Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells. 2009 至该文献
为研究哺乳动物活细胞中非肌肉肌球蛋白II的装配，使用了西格玛公司的抗NMHC-IIA抗体来进行蛋白印迹分析。 更多
甲状旁腺激素 (parathyroid hormone)
Kim-1
hepatitis A virus cellular receptor 1
总数:4
Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium. 2008 至该文献
Brigham妇女医院和哈佛医学院的小鼠抗Kim-1单克隆抗体被用于免疫组化实验来对尿液和肾脏中的肾损伤分子1和其他的肾毒性生物标记物进行比较。 更多
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
总数:5
Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection. 2005 至该文献
NPPB
natriuretic peptide B
TRPC6
transient receptor potential cation channel, subfamily C, member 6
总数:7
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. 2006 至该文献
KL
klotho
TWEAK
tumor necrosis factor (ligand) superfamily, member 12
总数:1
TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor. 2003 至该文献
为研究肿瘤坏死因子样弱凋亡因子（TWEAK）生物效应的调控作用，采用Cell Sciences公司生产的 TWEAK抗体用于免疫印迹实验。
Kir4.1
potassium inwardly-rectifying channel, subfamily J, member 10
总数:6
MLC1 is associated with the dystrophin-glycoprotein complex at astrocytic endfeet. 2007 至该文献
NPHS2
nephrosis 2, idiopathic, steroid-resistant (podocin)
总数:1
An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms. 2009 至该文献
为研究aPKC Lambda蛋白对于维护足状突细胞隔膜所起的作用，使用了西格玛公司的兔源抗Podocin抗体来进行免疫组化分析。
ACE2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
总数:6
Induction of apoptosis by the severe acute respiratory syndrome coronavirus 7a protein is dependent on its interaction with the Bcl-XL protein. 2007 至该文献
为了研究细胞凋亡是由于SARS-CoV蛋白与Bcl-XL相互作用所导致，使用Molecular Probes公司抗丙酮酸脱氢酶抗体进行western blot 实验。 更多
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 5
总数:1
Differential mechanism-based inhibition of CYP3A4 and CYP3A5 by verapamil. 2005 至该文献
AGTR2
angiotensin II receptor, type 2
总数:6
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 至该文献
为了研究缺血性心脏病病人体内ETB和AT1受体表达量上调，采用Santa Cruz的兔抗AT2抗体以1:50稀释进行免疫组织化学实验。 更多
HNF1B
HNF1 homeobox B
总数:5
HNF-1beta regulates transcription of the PKD modifier gene Kif12. 2009 至该文献
为了研究HNF-1beta在调控PKD修饰基因Kif12中的作用，采用了Santa Cruz Biotechnology公司的抗HNF1B抗体产品，进行了免疫印迹实验。 更多
NPPA
natriuretic peptide A
AHSG
alpha-2-HS-glycoprotein
总数:1
Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe. 2010 至该文献
为了研究非定向基于活性的蛋白解谱对识别活细胞中专一表达酶所起的作用，使用了R&D systems公司的抗fetuin A抗体来进行蛋白印迹分析。
血管紧张素转化酶 (ACE)
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
总数:8
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 至该文献
为了研究通过定量蛋白质组学发现新的BACE1底物，采用Santa Cruz的ACE抗体以1:1,000稀释进行蛋白印迹实验。 更多
PTX3
pentraxin 3, long
总数:2
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons. 2006 至该文献
visfatin
nicotinamide phosphoribosyltransferase
总数:1
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. 2010 至该文献
为了研究DBC1在调控SIRT1的活性和高脂饮食诱发的小鼠脂肪肝中的作用，采用了Bethyl Laboratories公司的NAMPT抗体产品，进行了免疫印迹实验
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
总数:8
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. 2008 至该文献
AGTR1
angiotensin II receptor, type 1
总数:9
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. 2009 至该文献
为了研究缺血性心脏病病人体内ETB和AT1受体表达量上调，采用Santa Cruz的兔抗AT1抗体进行免疫组织化学实验。 更多
connective tissue growth factor
总数:11
c-Abl tyrosine kinase regulates cardiac growth and development. 2010 至该文献
为了研究c-Abl酪氨酸激酶在调控心脏的生长和发育中的作用，采用了Santa Cruz Biotechnologies公司的抗CTGF抗体(1:2,000)，进行了免疫印迹实验 更多
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
总数:10
Concurrent induction and mechanism-based inactivation of CYP3A4 by an L-valinamide derivative. 2003 至该文献
为了研究由L - VALINAMIDE衍生物并发诱导及机理为基础的CYP3A4的灭活，采用了Chemicon International公司的CYP3A4抗体进行蛋白质印迹分析。 更多
CRP
C-reactive protein, pentraxin-related
总数:13
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. 2009 至该文献
为研究有活性的gp130在炎症性肝细胞肿瘤中所发挥的作用，将Abcam提供的单克隆抗C反应蛋白抗体应用于免疫组织化学实验中。 更多
osteoprotegerin
tumor necrosis factor receptor superfamily, member 11b
总数:2
Calcification of human vascular smooth muscle cells: associations with osteoprotegerin expression and acceleration by high-dose insulin. 2007 至该文献
在夹心酶联免疫分析实验中使用了R&D Systems公司的小鼠抗人OPG和生物素标记的山羊抗人OPG用于检测人血管平滑肌细胞条件培养基中OPG的浓度。 更多
RBP4
retinol binding protein 4, plasma
内皮素1 (endothelin 1)
总数:9
Expression of endothelial nitric oxide synthase and endothelin-1 in skin tissue from amputated limbs of patients with complex regional pain syndrome. 2008 至该文献
为了检测eNOS和ET-1的分布与在切断四肢的CRPS病人的皮肤组织中通过由内皮标记CD31免疫反应代表的血管浓度有关，采用R&D systems鼠的抗人ET-1抗体(3G10)，进行免疫组织化学实验。 更多
PON1
paraoxonase 1
总数:2
Oligomeric states of the detergent-solubilized human serum paraoxonase (PON1). 2002 至该文献
AGER
advanced glycosylation end product-specific receptor
TGF-beta1
transforming growth factor, beta 1
总数:33
Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 至该文献
为研究CD147促使成肌纤维细胞分化在组织变构中的作用，采用了R&D Systems公司的抗pan-TGFβ抗体进行抑制试验。 更多
VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor
总数:15
Vitamin d induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 至该文献
为了说明在膀胱中维生素D可以诱导一种人类抗菌肽cathelicidin的表达，采用了Affinity BioReagents公司的抗VDR（MA1-710，1：400）单克隆抗体进行免疫细胞化学实验。 更多
白细胞介素6 (IL-6)
interleukin 6 (interferon, beta 2)
总数:41
Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes.. 2011 至该文献
为了研究具有分解代谢功能的细胞器和具有合成代谢功能的细胞器二者在空间上的结合在促进分泌蛋白合成中的作用，采用R&D systems的抗IL6抗体进行免疫细胞化学试验。 更多
RET
ret proto-oncogene
总数:8
siRNA nanoformulation against the ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma. 2008 至该文献
为研究RET/PTC1癌基因特异性siRNA壳聚糖纳米颗粒在体内抑制甲状腺癌生长的效应，采用Abgent公司抗RET兔多克隆抗体（编号:AP7669b，0.25 mg/ml）进行了Western免疫印迹实验。 更多
白细胞介素18 (IL-18)
interleukin 18 (interferon-gamma-inducing factor)
总数:6
Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity.. 2005 至该文献
TNF-alpha
tumor necrosis factor
总数:64
NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. 2008 至该文献
为了研究NFAT5在高渗压力下对人类角膜缘上皮细胞的作用，采用了R&D Systems的TNF-alpha抗体进行了蛋白质印迹实验。 更多
脂联素 (adiponectin)
adiponectin, C1Q and collagen domain containing
总数:6
The mixed-lineage kinase DLK is a key regulator of 3T3-L1 adipocyte differentiation. 2009 至该文献
为了研究DLK在调控3T3-L1脂肪细胞分化中的作用，使用了Calbiochem公司的兔多克隆抗adiponectin抗体，进行了免疫印迹和沉淀实验。 更多
MCP-1
chemokine (C-C motif) ligand 2
总数:14
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 至该文献
为了研究单核细胞趋化蛋白1和CD40配基化对血管内皮生长因子产量的影响，采用了Santa Cruz公司的抗MCP-1抗体进行了免疫组织化学实验。 更多
MMP-2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
总数:37
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 至该文献
为了研究MMP2表达在人胰腺细胞系BxPC-3的浸润及黏附中的作用，采用了Santa Cruz公司的MMP-2单克隆抗体用于免疫印迹实验。 更多
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
总数:1
Regulation of human methylenetetrahydrofolate reductase by phosphorylation. 2005 至该文献