mRNA的加工
基因
试剂
文献样例
产品评述样例
ADAR
adenosine deaminase, RNA-specific
总数:1
Subcellular distribution of ADAR1 isoforms is synergistically determined by three nuclear discrimination signals and a regulatory motif. 2004 至该文献
ADARB1
adenosine deaminase, RNA-specific, B1
总数:1
Human scavenger receptor class B type II (SR-BII) and cellular cholesterol efflux. 2004 至该文献
ALYREF
Aly/REF export factor
总数:2
THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo. 2010 至该文献
为了研究THOC5/Fms在维护血细胞生成和调控THOC1中的作用,使用了Santa Cruz公司的单克隆抗Aly/THOC4 抗体,进行了免疫印迹实验。 更多
apobec 1 complementation factor
APOBEC1 complementation factor
总数:1
Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor. 2001 至该文献
APOBEC1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
AUF1
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
总数:3
Combinatorial control of signal-induced exon repression by hnRNP L and PSF. 2007 至该文献
为了研究核蛋白L( hnRNP L)和多嘧啶序列结合蛋白联合剪切因子(PSF)在信号诱导下遏制外显子表达的机理,采用了BioLegend公司的hnRNP D抗体,进行蛋白质印记实验。 更多
CCAR1
cell division cycle and apoptosis regulator 1
总数:1
Microtubule-dependent association of AKAP350A and CCAR1 with RNA stress granules. 2009 至该文献
为证明RNA压力颗粒与AKAP350A和CCAR1的结核是微管依赖性的,采用了Bethyl实验室的兔源抗CCAR1抗体进行蛋白质印迹、免疫沉淀和免疫荧光试验。
CCNH
cyclin H
总数:3
Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor. 2005 至该文献
为研究人牙本质基质蛋白1(Dmp1)在Ras-Raf-Arf信号通路传导中的作用,采用Santa Cruz生产的cyclin H抗体用于免疫印迹实验。 更多
CD2BP2
CD2 (cytoplasmic tail) binding protein 2
CDC40
cell division cycle 40 homolog (S. cerevisiae)
cdk7
cyclin-dependent kinase 7
总数:8
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression. 2011 至该文献
为了研究即刻早期反应基因表达调控因MED23突变而被破坏并导致智力障碍,采用Santa Cruz的多抗CDK7抗体进行ChIP和蛋白印迹实验。 更多
CPSF1
cleavage and polyadenylation specific factor 1, 160kDa
总数:1
The 3' ends of human pre-snRNAs are produced by RNA polymerase II CTD-dependent RNA processing. 2003 至该文献
为了阐明人前体snRNAs的3′末端是按照RNA加工程序来加工的,而不是转录终止,采用了Santa Cruz公司的抗CPSF 160抗体(1:500),进行了蛋白质印迹实验。
CPSF2
cleavage and polyadenylation specific factor 2, 100kDa
总数:1
Elevated levels of the 64-kDa cleavage stimulatory factor (CstF-64) in lipopolysaccharide-stimulated macrophages influence gene expression and induce alternative poly(A) site selection. 2005 至该文献
CPSF3
cleavage and polyadenylation specific factor 3, 73kDa
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
总数:2
Elevated levels of the 64-kDa cleavage stimulatory factor (CstF-64) in lipopolysaccharide-stimulated macrophages influence gene expression and induce alternative poly(A) site selection. 2005 至该文献
CSTF2
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
总数:1
The 3' ends of human pre-snRNAs are produced by RNA polymerase II CTD-dependent RNA processing. 2003 至该文献
为了阐明人前体snRNAs的3′末端是按照RNA加工程序来加工的,而不是转录终止,采用了Santa Cruz公司的抗CstF 64抗体(1:500),进行了蛋白质印迹实验。
CSTF3
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
总数:1
Elevated levels of the 64-kDa cleavage stimulatory factor (CstF-64) in lipopolysaccharide-stimulated macrophages influence gene expression and induce alternative poly(A) site selection. 2005 至该文献
D10S102
heterogeneous nuclear ribonucleoprotein A3
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DHX38
DEAH (Asp-Glu-Ala-His) box polypeptide 38
DHX9
DEAH (Asp-Glu-Ala-His) box polypeptide 9
总数:3
Nuclear DNA helicase II is recruited to IFN-alpha-activated transcription sites at PML nuclear bodies. 2002 至该文献
DNAJC8
DnaJ (Hsp40) homolog, subfamily C, member 8
EFTUD2
elongation factor Tu GTP binding domain containing 2
真核生物肽起始因子4e (eIF4E)
eukaryotic translation initiation factor 4E
总数:36
The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation. 2010 至该文献
为了将4E-BP鉴定为帕金森病相关的激酶LRRK2的一种相对较弱的直接底物,采用了Cell Signaling Technology公司的eIF4E抗体,进行了蛋白质印迹实验。 更多
ERCC2
excision repair cross-complementing rodent repair deficiency, complementation group 2
总数:2
Biochemical analysis of the damage recognition process in nucleotide excision repair. 2003 至该文献
ERCC3
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)
总数:4
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. 2011 至该文献
为了研究UV引起的DNA损伤及应激反应,采用了Santa Cruz XPB抗体进行了蛋白质印迹实验。 更多
FUS
fused in sarcoma
总数:6
A yeast model of FUS/TLS-dependent cytotoxicity. 2011 至该文献
为了研究酵母中FUS/TLS依赖的细胞毒性,采用了Abcamn公司的抗FUS抗体(1:1000)进行了免疫印记实验。 更多
GTF2F1
general transcription factor IIF, polypeptide 1, 74kDa
总数:3
Papillomavirus E2 proteins and the host BRD4 protein associate with transcriptionally active cellular chromatin. 2009 至该文献
为了研究乳头瘤E2蛋白、宿主Brd4蛋白与转录活性的基因之间的联系,使用了Santa Cruz公司的抗TFIIF抗体来进行ChIP分析。 更多
GTF2F2
general transcription factor IIF, polypeptide 2, 30kDa
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
总数:3
Casein kinase 2 interacts with cyclin-dependent kinase 11 (CDK11) in vivo and phosphorylates both the RNA polymerase II carboxyl-terminal domain and CDK11 in vitro. 2003 至该文献
在免疫印迹实验中使用了Santa Cruz Biotechnology公司的抗TFIIH p62抗体用于研究CDK11p110信号和蛋白复合物的特性以及其在转录和RNA表达中的作用。 更多
GTF2H2
general transcription factor IIH, polypeptide 2, 44kDa
GTF2H3
general transcription factor IIH, polypeptide 3, 34kDa
总数:1
IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells. 2009 至该文献
为了研究在脂肪基质细胞(ASCs)中对芳香化酶转录和雌性激素生物合成的调控机制,采用了Santa Cruz Biotechnology公司的TFIIH抗体,进行了蛋白质印迹实验。
GTF2H4
general transcription factor IIH, polypeptide 4, 52kDa
总数:1
Thrombopoietin induces HOXA9 nuclear transport in immature hematopoietic cells: potential mechanism by which the hormone favorably affects hematopoietic stem cells. 2004 至该文献
HEAB
CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)
hnRNP C1/C2
heterogeneous nuclear ribonucleoprotein C (C1/C2)
总数:10
Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer. 2009 至该文献
为了研究使得eIF4E基因水平控制在信使RNA稳定的水平这一机制,研究使用了Santa Cruz公司的anti-hnRNP C1/C2 Ab来进行蛋白印迹实验。 更多
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
HNRNPA1
heterogeneous nuclear ribonucleoprotein A1
总数:8
Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis. 2008 至该文献
为了研究RNA结合蛋白(RBPs)在慢性髓性白血病产生和进行时的转录后调节中的作用,采用了Sigma的单克隆抗hnRNP-A1抗体进行了免疫沉淀试验。 更多
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
总数:2
Regulation of gamma-fibrinogen chain expression by heterogeneous nuclear ribonucleoprotein A1. 2005 至该文献
HNRNPF
heterogeneous nuclear ribonucleoprotein F
总数:2
Proteomic identification of proteins associated with the osmoregulatory transcription factor TonEBP/OREBP: functional effects of Hsp90 and PARP-1. 2007 至该文献
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
总数:2
Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. 2010 至该文献
为了研究TDP-43与众多调节RNA代谢的蛋白之间的相互作用,采用Abcam的抗hnRNP H抗体进行免疫印迹试验。 更多
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
HNRNPK
heterogeneous nuclear ribonucleoprotein K
总数:6
Proteomic and genomic analysis of PITX2 interacting and regulating networks. 2009 至该文献
为了研究PITX2相关联的蛋白与基因网络,使用了Epitomics公司的抗hnRNP K抗体来进行蛋白印迹分析。 更多
HNRNPL
heterogeneous nuclear ribonucleoprotein L
总数:3
Combinatorial control of signal-induced exon repression by hnRNP L and PSF. 2007 至该文献
为了研究核蛋白L( hnRNP L)和多嘧啶序列结合蛋白联合剪切因子(PSF)在信号诱导下遏制外显子表达的机理,采用了Abcam公司的核蛋白L抗体,进行蛋白质印记实验。 更多
HNRNPM
heterogeneous nuclear ribonucleoprotein M
HNRNPR
heterogeneous nuclear ribonucleoprotein R
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
总数:2
Proteomic and genomic analysis of PITX2 interacting and regulating networks. 2009 至该文献
为了研究PITX2相关联的蛋白与基因网络,使用了Abcam公司的抗hnRNP U抗体来进行蛋白印迹分析。 更多
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
总数:1
Influenza virus targets the mRNA export machinery and the nuclear pore complex. 2007 至该文献
为了研究甲型流感病毒破坏mRNA核输出装置的机制,采用了Proteintech Group公司的抗E1B-AP5抗体,进行了蛋白质印迹实验。
LSM10
LSM10, U7 small nuclear RNA associated
LSM11
LSM11, U7 small nuclear RNA associated
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAGOH
mago-nashi homolog, proliferation-associated (Drosophila)
总数:3
The exon junction complex component Magoh controls brain size by regulating neural stem cell division. 2010 至该文献
为研究Magoh控制小鼠大脑大小的遗传学机制,采用了Proteintech的抗Magoh抗体进行了免疫组织化学实验。 更多
MNAT1
menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)
总数:2
Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". 2006 至该文献
NCBP1
nuclear cap binding protein subunit 1, 80kDa
总数:2
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 至该文献
为了研究监视因子复合体与核糖体在无义介导mRNA降解过程中的合作机制,采用了Protein-Tech公司核帽结合蛋白亚基1抗体,进行蛋白质印记实验。 更多
NCBP2
nuclear cap binding protein subunit 2, 20kDa
总数:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 至该文献
为了研究SMG-1激酶在无义介导的mRNA降解过程中的调节机制,采用了Abgent公司的CBP20抗体,进行了蛋白质印迹实验。
NFX1
nuclear transcription factor, X-box binding 1
NHP2L1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
NUDT21
nudix (nucleoside diphosphate linked moiety X)-type motif 21
NXF1
nuclear RNA export factor 1
总数:4
Nuclear export factor RBM15 facilitates the access of DBP5 to mRNA. 2009 至该文献
为了研究RBM15在DBP5与mRNA之间的接触过程中所起的促进作用,使用了Santa Cruz公司的抗NXF1抗体来进行免疫组化分析。 更多
PABPN1
poly(A) binding protein, nuclear 1
PCF11
PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
总数:1
Transcription termination factor Pcf11 limits the processivity of Pol II on an HIV provirus to repress gene expression. 2007 至该文献
POLR2B
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
总数:1
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis. 2009 至该文献
为研究STAGA亚单位ADA2b在调节人GCN5催化作用中所扮演的角色,将Santa Cruz提供的抗RNA聚合酶II大亚单位抗体(N20)用于蛋白免疫印迹实验中。
POLR2F
polymerase (RNA) II (DNA directed) polypeptide F
总数:3
Developmentally specific role of the CCAAT box in regulation of human gamma-globin gene expression. 2004 至该文献
PRPF4
PRP4 pre-mRNA processing factor 4 homolog (yeast)
PRPF6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)
PRPF8
PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)
总数:1
Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome. 2007 至该文献
PTBP1
polypyrimidine tract binding protein 1
总数:1
Alternative splicing of the multidrug resistance protein 1/ATP binding cassette transporter subfamily gene in ovarian cancer creates functional splice variants and is associated with increased expression of the splicing factors PTB and SRp20. 2004 至该文献
RBM8A
RNA binding motif protein 8A
总数:1
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. 2009 至该文献
为了研究SMG-1激酶在无义介导的mRNA降解过程中的调节机制,采用了Sigma公司的Y14抗体,进行了蛋白质印迹实验。
RBMX
RNA binding motif protein, X-linked
RNA聚合酶II (RNA polymerase II)
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
总数:69
RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processing. 2011 至该文献
为了研究组蛋白mRNA的3末端处理需要对RNA聚合酶II的4位苏氨酸进行磷酸化,采用Santa Cruz的抗Rpb1抗体进行蛋白印迹和ChIP实验。 更多
RNGTT
RNA guanylyltransferase and 5'-phosphatase
总数:1
Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells. 2002 至该文献
RNMT
RNA (guanine-7-) methyltransferase
RNPS1
RNA binding protein S1, serine-rich domain
SC35
serine/arginine-rich splicing factor 2
总数:17
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. 2010 至该文献
为研究敲低TDP-43介导的HDAC6下调作用,采用了Sigma公司的鼠源抗SC35抗体(1:5000)进行免疫荧光试验。 更多
SF3A1
splicing factor 3a, subunit 1, 120kDa
SF3A2
splicing factor 3a, subunit 2, 66kDa
SF3A3
splicing factor 3a, subunit 3, 60kDa
SF3B1
splicing factor 3b, subunit 1, 155kDa
SF3B14
splicing factor 3B, 14 kDa subunit
SF3B2
splicing factor 3b, subunit 2, 145kDa
总数:1
CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA. 2009 至该文献
为了研究CUGBP2激活心肌钙蛋白T外显子5的保留的机制,使用了Proteintech Group公司的兔抗SF3B145多克隆抗体来进行免疫印迹分析。
SF3B3
splicing factor 3b, subunit 3, 130kDa
SF3B4
splicing factor 3b, subunit 4, 49kDa
总数:1
CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA. 2009 至该文献
为了研究CUGBP2激活心肌钙蛋白T外显子5的保留的机制,使用了Proteintech Group公司的兔抗SF3b49多克隆抗体来进行免疫印迹分析。
SF3B5
splicing factor 3b, subunit 5, 10kDa
Smc1
structural maintenance of chromosomes 1A
总数:14
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination. 2010 至该文献
为了研究PTIP促进特异性的染色质改变和免疫球蛋白类别转换重组的机制,使用了Novus公司的兔抗SMC1抗体来进行染色质免疫沉淀实验。 更多
SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
SNRNP40
small nuclear ribonucleoprotein 40kDa (U5)
SNRPA
small nuclear ribonucleoprotein polypeptide A
总数:1
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 至该文献
为了研究RNA聚合酶II在转录拼接中的延长作用使用了Abcam公司的兔抗U1A抗体来进行免疫沉淀作用。
SNRPA1
small nuclear ribonucleoprotein polypeptide A'
SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
总数:4
The honey bee epigenomes: differential methylation of brain DNA in queens and workers. 2010 至该文献
为了说明WRAP53是形成卡恰尔身体的必要因素并且能够将SMN复合体定位到卡恰尔身体,使用了Santa Cruz Biotechnology公司的alpha-SmB/B鼠抗(sc-271094)来进行免疫印记,免疫沉淀和免疫细胞组化实验。 更多
SNRPB2
small nuclear ribonucleoprotein polypeptide B
SNRPD1
small nuclear ribonucleoprotein D1 polypeptide 16kDa
总数:1
Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein. 2001 至该文献
SNRPD2
small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPD3
small nuclear ribonucleoprotein D3 polypeptide 18kDa
SNRPE
small nuclear ribonucleoprotein polypeptide E
总数:3
Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. 2008 至该文献
为了检测蛋白酶体抑制剂和组蛋白酰基转移酶抑制剂在GBM细胞株中产生的效应,采用了Santa Cruz Biotechnology的鼠抗B-Raf单抗,进行蛋白质印迹实验 更多
SNRPF
small nuclear ribonucleoprotein polypeptide F
SNRPG
small nuclear ribonucleoprotein polypeptide G
SRp20
serine/arginine-rich splicing factor 3
总数:5
SRp20 and CUG-BP1 modulate insulin receptor exon 11 alternative splicing. 2009 至该文献
为研究SRp20和CUG-BP1在调控胰岛素受体外显子11的交替拼接中所发挥的角色,将ATCC提供的表达SRp20抗体的杂交瘤细胞培养上清液(CRL-2384)用于Hela细胞核提取物的免疫耗竭实验中。 更多
SRRM1
serine/arginine repetitive matrix 1
总数:1
Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin. 2005 至该文献
SRSF1
serine/arginine-rich splicing factor 1
总数:4
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 至该文献
为了研究RNA聚合酶II在转录拼接中的延长作用使用了Zymed公司的鼠抗SF2/ASF抗体来进行免疫沉淀作用。 更多
SRSF11
serine/arginine-rich splicing factor 11
SRSF4
serine/arginine-rich splicing factor 4
总数:1
Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells. 2003 至该文献
SRSF5
serine/arginine-rich splicing factor 5
总数:4
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. 2010 至该文献
为了说明arrestin-2/STAM-1复合体通过泛素化HRS调节CXCR4溶酶体分选,使用了Santa Cruz Biotechnology公司的HRS兔多抗(M-79)来进行免疫印记实验。 更多
SRSF6
serine/arginine-rich splicing factor 6
总数:1
Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells. 2003 至该文献
SRSF7
serine/arginine-rich splicing factor 7
总数:1
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 至该文献
为了研究RNA聚合酶II在转录拼接中的延长作用使用了BD Bioscience公司的鼠抗9G8抗体来进行免疫沉淀作用。
SRSF9
serine/arginine-rich splicing factor 9
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
总数:2
Transcription termination factor Pcf11 limits the processivity of Pol II on an HIV provirus to repress gene expression. 2007 至该文献
U2AF1
U2 small nuclear RNA auxiliary factor 1
U2AF2
U2 small nuclear RNA auxiliary factor 2
总数:2
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. 2011 至该文献
为了研究RNA聚合酶II在转录拼接中的延长作用使用了Abcam公司的兔抗U2AF65抗体来进行免疫沉淀作用。 更多
UPF3B
UPF3 regulator of nonsense transcripts homolog B (yeast)
YB 1
Y box binding protein 1
总数:5
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 至该文献
为了说明YB-1、GST、ABCB5和ERK3能够成为乳腺癌细胞耐药性治疗的潜在靶点,使用了Cell Signalling公司的YB-1抗体(1:200)来进行免疫印记实验。 更多