多发性硬化症
基因
试剂
文献样例
产品评述样例
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
总数:6
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.. 2011 至该文献
为了研究人造血系统细胞给以不同刺激的反应能通过单细胞多因子分选进行分析,采用Biolegend的抗HLADR抗体以2ug/ml浓度进行细胞多因子分选实验。 更多
IL7R
interleukin 7 receptor
总数:5
No Evidence of Murine-Like Gammaretroviruses in CFS Patients Previously Identified as XMRV-Infected.. 2011 至该文献
为了研究慢性疲劳症候群病人未感染鼠gamma逆转录病毒,采用Immunotech的抗CDw127抗体进行PCR实验。 更多
CD58
CD58 molecule
总数:5
Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes. 2005 至该文献
CD6
CD6 molecule
总数:1
The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence.. 2011 至该文献
为了研究血脑屏障的完整性和中枢神经免疫沉默能够被Shh信号通路促进,采用BD Biosciences的抗CD6抗体进行流式细胞分选实验。
CLEC16A
C-type lectin domain family 16, member A
CD25
interleukin 2 receptor, alpha
总数:44
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. 2009 至该文献
为了研究树突细胞在调控自发性致死性自身免疫性疾病中的作用,采用了eBioscience公司的抗CD25抗体产品,进行了流失细胞分析实验。 更多
EVI5
ecotropic viral integration site 5
FAM69A
family with sequence similarity 69, member A
髓磷脂碱蛋白 (MBP)
myelin basic protein
总数:34
Expanding the genetic code of Escherichia coli with phosphoserine.. 2011 至该文献
为了研究大肠杆菌能够被改造后通过密码子编码磷酸化的丝氨酸,采用New England Biolabs的抗MBP抗体进行蛋白印迹实验。 更多
IRF8
interferon regulatory factor 8
总数:4
IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways. 2006 至该文献
CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
总数:3
LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy. 2007 至该文献
HLA-A
major histocompatibility complex, class I, A
总数:8
Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice. 2008 至该文献
为了研究研究肿瘤和肿瘤基质细胞间的相互作用,采用了Santa Cruz Biotechnology HLA-A(A-18)抗体进行了免疫组化实验。 更多
Tyk2
tyrosine kinase 2
总数:13
Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth. 2008 至该文献
为研究新型酪氨酸激酶JAK-2抑制剂Z3可以抑制JAK-2介导的病理性细胞生长,采用了Santa Cruz 生物技术公司的抗Tyk2和抗磷酸化TyK2多克隆抗体分别进行免疫共沉淀实验和western免疫印迹实验。 。 更多
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
总数:1
Expression of CD80 and CD86 costimulatory molecules are potential markers for better survival in nasopharyngeal carcinoma. 2007 至该文献
为了研究CD80和CD86可能作为鼻咽癌预后的标记物,采用Novocastra Laboratories的抗HLA Class II (DR)抗体进行免疫组织化学实验。
TNFR1
tumor necrosis factor receptor superfamily, member 1A
总数:23
Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation. 2009 至该文献
为了研究TRAF2对应激诱导的细胞死亡的抑制机制,采用了Santa Cruz的抗TNFR1抗体进行免疫印迹实验 更多
IFNB1
interferon, beta 1, fibroblast
总数:8
Expression of Toll-like receptors in verruca and molluscum contagiosum. 2008 至该文献
为了在人体皮肤的冷冻切片上研究Toll样受体在疣和传染性软疣的表现,使用了Santa Cruz Biotechnology公司的兔多克隆的抗人体TNF-β产品,进行了免疫组织化学实验。 更多
HLA-DR
major histocompatibility complex, class II, DR alpha
总数:21
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 至该文献
为了研究IRAK-1信号阻断对TLR2和TLR4诱导的人树突状细胞耐受有重要作用,采用Beckman-Coulter的抗HLA DR- PC5抗体进行流式细胞分选实验。 更多
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
总数:2
Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. 2008 至该文献
DPB1
major histocompatibility complex, class II, DP beta 1
IFIH1
interferon induced with helicase C domain 1
总数:2
Role of retinoic acid inducible gene-I in human metapneumovirus-induced cellular signalling. 2008 至该文献
为了研究呼由人变性肺病毒引起的吸道上皮细胞的细胞信号转导,采用了IMGENEX公司的抗MDA-5抗体进行免疫印迹实验。 更多
CIITA
class II, major histocompatibility complex, transactivator
总数:5
A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages. 2009 至该文献
为了研究JAK-STAT1通道在调控HSV-1复制中的作用,使用了Biolegend公司的抗MHC class II-APC 抗体,来收集和染色受感染的细胞,进行了流式细胞计量实验。 更多
CB2
cannabinoid receptor 2 (macrophage)
总数:5
Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains. 2003 至该文献
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
总数:1
Vitamin d induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 至该文献
为了说明在膀胱中维生素D可以诱导一种人类抗菌肽cathelicidin的表达,采用了Santa Cruz公司的抗CYP27B1(D-20,1:200)多克隆抗体进行免疫细胞化学实验。
HLA DQA1
major histocompatibility complex, class II, DQ alpha 1
总数:4
Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid beta-protein. 2002 至该文献
HLA-C
major histocompatibility complex, class I, C
总数:7
Identification of major histocompatibility complex class I C molecule as an attachment factor that facilitates coronavirus HKU1 spike-mediated infection. 2009 至该文献
为了研究主要组织相容性复合体作为一种附属因子在促进 HCoV-HKU1 感染过程中的作用,采用英杰的纯化的羊免疫球蛋白作为同型标准品。 更多
白细胞介素17 (IL-17)
interleukin 17A
总数:16
The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence.. 2011 至该文献
为了研究血脑屏障的完整性和中枢神经免疫沉默能够被Shh信号通路促进,采用eBioscience的抗IL-17抗体进行流式细胞分选实验。 更多
人类白细胞抗原b (HLA B)
major histocompatibility complex, class I, B
总数:1
Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes. 2005 至该文献
白细胞介素2 (interleukin 2)
总数:15
Identification of IL-17-producing FOXP3+ regulatory T cells in humans. 2009 至该文献
为了确定IL-17+,FOXP3+调节性T细胞产生于外周血中,使用了R&D Systems公司的白介素2酶联免疫吸附试剂盒进行酶联免疫吸附实验。 更多
白细胞介素12 (IL-12)
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
总数:9
Importance of stromal determinants in the generation of dendritic and natural killer cells in the human spleen.. 2005 至该文献
AQP4
aquaporin 4
总数:10
Close association of water channel AQP1 with amyloid-beta deposition in Alzheimer disease brains. 2008 至该文献
采用Santa Cruz生物技术公司的抗AQP4抗体(H-80),进行免疫组织化学实验来研究AQP4在阿尔茨海默病人的大脑皮层中的表达。 更多
VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor
总数:15
Vitamin d induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 至该文献
为了说明在膀胱中维生素D可以诱导一种人类抗菌肽cathelicidin的表达,采用了Affinity BioReagents公司的抗VDR(MA1-710,1:400)单克隆抗体进行免疫细胞化学实验。 更多
CD40
CD40 molecule, TNF receptor superfamily member 5
总数:39
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. 2010 至该文献
为了揭示HOIP在CD40信号通路中的泛素连接酶功能,使用了Santa Cruz Biotechnology公司的CD40抗体(H-120)来进行免疫印记实验。 更多
CTLA 4
cytotoxic T-lymphocyte-associated protein 4
总数:5
Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell Extrinsic Function of CTLA-4.. 2011 至该文献
为了揭示CTLA-4为何能够抑制CD28的激活,采用Santa Cruz的抗CTLA-4抗体进行免疫细胞化学试验。 更多
ApoE基因 (ApoE)
apolipoprotein E
总数:17
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 至该文献
为了研究高效肝炎C病毒颗粒的形成条件,采用了Calbiochem公司的抗ApoE抗体进行蛋白免疫印迹实验。 更多
IFN-gamma
interferon, gamma
总数:59
The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence.. 2011 至该文献
为了研究血脑屏障的完整性和中枢神经免疫沉默能够被Shh信号通路促进,采用R&D Systems的抗IFN-gamma抗体以5ug/ml浓度进行细胞刺激实验。 更多
TNF-alpha
tumor necrosis factor
总数:64
NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. 2008 至该文献
为了研究NFAT5在高渗压力下对人类角膜缘上皮细胞的作用,采用了R&D Systems的TNF-alpha抗体进行了蛋白质印迹实验。 更多
KIR3DS1
killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
HLA G
major histocompatibility complex, class I, G
总数:1
HLA-G gene repression is reversed by demethylation. 2003 至该文献
CNR1
cannabinoid receptor 1 (brain)
总数:3
Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. 2008 至该文献
为了确认内源性大麻素信号途径的关键元件是否在骨关节炎和类风湿性关节炎患者的关节骨液中表达,采用了Calbiochem公司的抗大麻素受体1抗体进行了蛋白印迹实验。 更多
白细胞介素10 (IL-10)
interleukin 10
总数:20
Identification of IL-17-producing FOXP3+ regulatory T cells in humans. 2009 至该文献
为了确定IL-17+,FOXP3+调节性T细胞产生于外周血中,使用了R&D Systems公司的白介素10酶联免疫吸附试剂盒进行酶联免疫吸附实验。 更多
BDNF
brain-derived neurotrophic factor
总数:11
Differential expression of neurotrophins in postnatal C57BL/6 mice striatum. 2009 至该文献
在免疫组化实验中使用Chemicon International抗BDNF抗体,来证明新生C57BL/6小鼠脑皮层神经营养因子的表达差异。 更多
Toll样受体9 (TLR9)
toll-like receptor 9
总数:6
Expression of Toll-like receptors in verruca and molluscum contagiosum. 2008 至该文献
为了在人体皮肤的冷冻切片上研究Toll样受体在疣和传染性软疣的表现,使用了Santa Cruz Biotechnology公司的羊多克隆的抗人体TLR9产品,进行了免疫组织化学实验。 更多
OPN
secreted phosphoprotein 1
总数:12
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 至该文献
为了研究c-Src激酶是否会促使非典型小叶增生或小叶原位癌转变为浸润性小叶癌,使用了Calbiochem公司的抗osteopontin抗体(1:100)进行免疫荧光实验。 更多
MMP-9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
总数:44
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 至该文献
为了研究蛋白激酶D1抑制乳腺肿瘤细胞侵袭的机制,采用了Epitomics公司的抗MMP-9抗体,进行了免疫组织化学实验。 更多
MCP-1
chemokine (C-C motif) ligand 2
总数:14
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 至该文献
为了研究单核细胞趋化蛋白1和CD40配基化对血管内皮生长因子产量的影响,采用了Santa Cruz公司的抗MCP-1抗体进行了免疫组织化学实验。 更多
IL1RN
interleukin 1 receptor antagonist
总数:1
Beta-(1-->3)-D-glucan modulates DNA binding of nuclear factors kappaB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1beta/IL-1 receptor antagonist ratio. 2006 至该文献
IL1A
interleukin 1, alpha
总数:5
Intracellular IL-1alpha-binding proteins contribute to biological functions of endogenous IL-1alpha in systemic sclerosis fibroblasts. 2006 至该文献
白细胞介素1beta (IL-1beta)
interleukin 1, beta
总数:28
Local and systemic responses in matrix metalloproteinase 8-deficient mice during Porphyromonas gingivalis-induced periodontitis. 2009 至该文献
为了研究牙龈卟啉单胞菌所致牙周炎中基质金属蛋白酶8的作用,在免疫染色试验中将R&D Systems的interleukin-1β作用于石蜡包被的组织样品上。 更多
AGER
advanced glycosylation end product-specific receptor
FOXP3
forkhead box P3
总数:15
Identification of IL-17-producing FOXP3+ regulatory T cells in humans. 2009 至该文献
为了确定IL-17+,FOXP3+调节性T细胞产生于外周血中,使用了eBioscience公司的标记有藻红蛋白或别藻蓝蛋白的抗FOXP3抗体(克隆PCH101)进行免疫荧光实验。 更多
白细胞介素6 (IL-6)
interleukin 6 (interferon, beta 2)
总数:41
Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes.. 2011 至该文献
为了研究具有分解代谢功能的细胞器和具有合成代谢功能的细胞器二者在空间上的结合在促进分泌蛋白合成中的作用,采用R&D systems的抗IL6抗体进行免疫细胞化学试验。 更多
NOD2
nucleotide-binding oligomerization domain containing 2
总数:2
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. 2006 至该文献
趋化因子受体4 (CXCR4)
chemokine (C-X-C motif) receptor 4
总数:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.. 2011 至该文献
为了研究人造血系统细胞给以不同刺激的反应能通过单细胞多因子分选进行分析,采用Biolegend的抗CXCR4抗体以3ug/ml浓度进行细胞多因子分选实验。 更多