心肌梗死
基因
试剂
文献样例
产品评述样例
PGIS
prostaglandin I2 (prostacyclin) synthase
总数:4
Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages. 2005 至该文献
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
总数:2
Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation. 2009 至该文献
为了在内质网相关蛋白的降解途径（ERAD）中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能，使用了Enzo Life Sciences公司的抗体alpha6来进行免疫印迹分析。 更多
BTN2A1
butyrophilin, subfamily 2, member A1
FGB
fibrinogen beta chain
总数:1
Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation. 2009 至该文献
为了研究魁北克血小板障碍病中uPA的高表达和巨核细胞分化的关联，使用了Behring公司的兔抗fibrinogen抗体来进行免疫荧光实验。
MEF2A
myocyte enhancer factor 2A
总数:6
A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiation. 2006 至该文献
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
总数:1
miR-33 Contributes to the Regulation of Cholesterol Homeostasis.. 2010 至该文献
为了研究内含子区的miRNA miR-33在胆固醇代谢调节中的功能，使用了Santa Cruz Biotechnology公司的抗HMGCR多克隆抗体来进行免疫印迹分析。
TBXAS1
thromboxane A synthase 1 (platelet)
总数:3
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. 2009 至该文献
为研究高密度SNP基础的基因型排列分析检测小儿低级星形细胞瘤7q34重复区发现的新型BRAF融合基因，采用了Abcam公司的抗TBXAS1抗体进行蛋白质印迹试验。 更多
TNNI3
troponin I type 3 (cardiac)
总数:5
Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. 2008 至该文献
进行为了研究在β1AR刺激的肌细胞收缩过程中，PP2A限制PKA对受磷蛋白和Tnl磷酸化的作用，采用了Cell Signaling Technology的磷酸化Ser23，24Tnl抗体，进行蛋白质印迹实验 更多
CETP
cholesteryl ester transfer protein, plasma
LPA
lipoprotein, Lp(a)
SORT1
sortilin 1
总数:3
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. 2005 至该文献
TANGO
melanoma inhibitory activity family, member 3
CRP
C-reactive protein, pentraxin-related
总数:13
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. 2009 至该文献
为研究有活性的gp130在炎症性肝细胞肿瘤中所发挥的作用，将Abcam提供的单克隆抗C反应蛋白抗体应用于免疫组织化学实验中。 更多
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
纤维蛋白原 (fibrinogen)
fibrinogen alpha chain
总数:4
Biomarkers for ragwort poisoning in horses: identification of protein targets. 2008 至该文献
TNNT2
troponin T type 2 (cardiac)
总数:3
Functional cardiomyocytes derived from human induced pluripotent stem cells. 2009 至该文献
为了研究人类诱导的多功能干细胞的心肌细胞的功能，采用了Thermo Scientific的cTnT 抗体进行免疫标记。 更多
KIF6
kinesin family member 6
NPPB
natriuretic peptide B
PCSK9
proprotein convertase subtilisin/kexin type 9
总数:2
Antibody-mediated disruption of the interaction between PCSK9 and the low-density lipoprotein receptor. 2009 至该文献
为阐明PCSK9特异性抗体可以逆转PCSK9介导的对细胞表面LDLRs的下调作用，采用了Abcam的羊抗人PCSK9多克隆抗体（catalog #:Ab28770）进行抗体阻断实验。 更多
F13A1
coagulation factor XIII, A1 polypeptide
P2Y12
purinergic receptor P2Y, G-protein coupled, 12
PON1
paraoxonase 1
总数:2
Oligomeric states of the detergent-solubilized human serum paraoxonase (PON1). 2002 至该文献
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
F7
coagulation factor VII (serum prothrombin conversion accelerator)
总数:1
Extrahepatic synthesis of factor VII in human atherosclerotic vessels. 2003 至该文献
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
总数:2
Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in endothelial cells by nitric oxide deficiency. 2004 至该文献
为了阐明不对称二甲基精氨酸的水平，采用了Sigma公司的鼠抗LOX-1的多克隆抗体进行蛋白质印迹分析 更多
MMP-3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
总数:8
Matrix metalloproteinase activity in pediatric acute lung injury. 2009 至该文献
为了研究基质中金属蛋白酶在儿童急性肺损伤中的作用，使用了R/D Systems公司的MMP-3抗体来进行免疫印迹实验。 更多
血管性血友病因子 (von Willebrand factor)
总数:32
Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells. 2009 至该文献
为研究Rab27a和MyRIP对内皮细胞释放的血管假性血友病因子的调节作用，使用了Serotec公司的羊源性VWF抗体检测假性血友病因子。 更多
LIPC
lipase, hepatic
ADRB1
adrenergic, beta-1-, receptor
总数:2
Leptin repletion restores depressed {beta}-adrenergic contractility in ob/ob mice independently of cardiac hypertrophy. 2005 至该文献
Affinity Bioreagents的β1 肾上腺素受体抗体被用于蛋白质印迹实验，来研究在心脏中瘦蛋白活化的机制。 更多
apoA-I
apolipoprotein A-I
总数:13
Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. 2008 至该文献
为了在一个转基因小鼠模型中研究载脂蛋白成员的不同作用，采用 Abcam公司的兔多克隆抗apoA-I抗体产品(1:10,000)，进行了免疫印迹实验。 更多
髓过氧化酶 (myeloperoxidase)
总数:7
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation. 2010 至该文献
为了研究心房纤颤病理过程中髓过氧化物酶的作用，采用了Calbiochem公司的抗MPO（475915）抗体进行免疫组化实验。 更多
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
脂蛋白脂肪酶 (lipoprotein lipase)
总数:2
Maternal loading with very low-density lipoproteins stimulates fetal surfactant synthesis. 2002 至该文献
eNOS
nitric oxide synthase 3 (endothelial cell)
总数:36
Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells. 2009 至该文献
为了研究purinergic在调控内皮细胞一氧化氮合成酶活性中的作用，采用了Upstate Laboratories公司的抗eNOS抗体产品，进行了免疫印迹实验。 更多
白细胞介素6 (IL-6)
interleukin 6 (interferon, beta 2)
总数:41
Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes.. 2011 至该文献
为了研究具有分解代谢功能的细胞器和具有合成代谢功能的细胞器二者在空间上的结合在促进分泌蛋白合成中的作用，采用R&D systems的抗IL6抗体进行免疫细胞化学试验。 更多
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
总数:1
Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8, 2C9, and 2J2 in human tissues. 2004 至该文献
FGG
fibrinogen gamma chain
PAI-1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
总数:15
Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. 2010 至该文献
为了研究人纤溶酶原和钩端螺旋体内皮抑制素样蛋白A之间的相互作用，采用Novus Biologicals公司的山羊抗人纤溶酶原抗体进行酶联免疫吸附实验。 更多
血管紧张素转化酶 (ACE)
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
总数:8
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 至该文献
为了研究通过定量蛋白质组学发现新的BACE1底物，采用Santa Cruz的ACE抗体以1:1,000稀释进行蛋白印迹实验。 更多
因子V (factor V)
coagulation factor V (proaccelerin, labile factor)
总数:4
Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation. 2009 至该文献
为了研究魁北克血小板障碍病中uPA的高表达和巨核细胞分化的关联，使用了Affinity Biologicals公司的羊抗凝血因子V抗体来进行免疫荧光实验。 更多
载脂蛋白B (apoB)
apolipoprotein B (including Ag(x) antigen)
总数:14
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. 至该文献
为了研究高效肝炎C病毒颗粒的形成条件，采用了Abcam公司的抗ApoB100抗体进行蛋白免疫印迹实验。 更多
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
CAPON
nitric oxide synthase 1 (neuronal) adaptor protein
CPB2
carboxypeptidase B2 (plasma)
总数:1
Development of sandwich-type ELISAs for the quantification of rat and murine thrombin activatable fibrinolysis inhibitor in plasma. 2008 至该文献
为研发一种酶联免疫吸附测定小鼠和大鼠血浆中凝血酶活化的纤溶抑制剂TAFI定量的方法，采用A. GILS生产的TAFI抗体用于ELISA实验。
MMP-9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
总数:44
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 至该文献
为了研究蛋白激酶D1抑制乳腺肿瘤细胞侵袭的机制，采用了Epitomics公司的抗MMP-9抗体，进行了免疫组织化学实验。 更多
TNF-alpha
tumor necrosis factor
总数:64
NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. 2008 至该文献
为了研究NFAT5在高渗压力下对人类角膜缘上皮细胞的作用，采用了R&D Systems的TNF-alpha抗体进行了蛋白质印迹实验。 更多
CD40配体 (CD40 ligand)
总数:12
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 至该文献
为了研究单核细胞趋化蛋白1和CD40配基化对血管内皮生长因子产量的影响，采用了Santa Cruz公司的抗CD40L抗体(1:200)进行了免疫组织化学实验。 更多
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
总数:3
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. 2009 至该文献
为了介绍在急性肾损伤时线粒体动力学的一种快速调节，使用了BD Biosciences — Pharmingen公司的单克隆抗cytochrome c抗体来进行免疫组化实验。 更多
tissue factor
coagulation factor III (thromboplastin, tissue factor)
总数:5
Versican G3 domain promotes blood coagulation through suppressing the activity of tissue factor pathway inhibitor-1. 2006 至该文献
SLCO1B1
solute carrier organic anion transporter family, member 1B1
总数:2
Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. 2006 至该文献
P-selectin
selectin P (granule membrane protein 140kDa, antigen CD62)
总数:8
Effect of tumour necrosis factor-alpha receptor 1 genetic deletion on carrageenan-induced acute inflammation: a comparison with etanercept. 2008 至该文献
为了评估体内肿瘤坏死因子-αR1在炎症疾病发病机理的作用，采用了Santa Cruz生物技术公司的抗P-选择素抗体（1:500）进行了免疫组化实验。 更多
LTA
lymphotoxin alpha (TNF superfamily, member 1)
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
总数:4
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 至该文献
LDLR
low density lipoprotein receptor
总数:10
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation. 2009 至该文献
为了表明N-钙粘素-轴蛋白-LRP5的反应对Wnt/β-钙粘素信号，成骨蛋白功能及骨形成有负调控作用，使用了Santa Cruz公司的抗-LDLr抗体进行免疫印迹实验。 更多
F2
coagulation factor II (thrombin)
总数:2
Identification of sequences within the gamma-carboxylase that represent a novel contact site with vitamin K-dependent proteins and that are required for activity. 2001 至该文献
CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
总数:1
Cyclin K and cyclin D1b are oncogenic in myeloma cells. 2010 至该文献
为了研究多发性骨髓瘤中细胞周期蛋白K和细胞周期蛋白D1b的作用，采用了Santa Cruz的抗p15抗体进行免疫印迹实验。
ADRB2
adrenergic, beta-2-, receptor, surface
总数:7
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. 2009 至该文献
为了研究β2-肾上腺素受体激动剂fenoterol的立体化学在决定受体G蛋白选择性和下游信号通路中的功能，使用了Santa Cruz Biotechnology公司的抗ADRB2 C末端抗体来进行免疫印迹分析。 更多
PON2
paraoxonase 2
MMP-1
matrix metallopeptidase 1 (interstitial collagenase)
总数:12
Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 至该文献
为研究CD147促使成肌纤维细胞分化在组织变构中的作用，采用了Calbiochem公司的抗MMP-1单克隆抗体进行蛋白质印迹试验。 更多
VCAM-1
vascular cell adhesion molecule 1
总数:19
The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways. 2009 至该文献
为研究前列腺特异膜抗原在前列腺癌细胞的白介素6和CCL5的表达调控中所发挥的角色，将Immunotech提供的抗血管细胞粘附分子抗体用于阻断或激活实验中。 更多
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
总数:10
miR-33 Contributes to the Regulation of Cholesterol Homeostasis.. 2010 至该文献
为了研究内含子区的miRNA miR-33在胆固醇代谢调节中的功能，使用了Abcam公司的小鼠抗ABCA1单克隆抗体来进行免疫印迹分析。 更多
白细胞介素10 (IL-10)
interleukin 10
总数:20
Identification of IL-17-producing FOXP3+ regulatory T cells in humans. 2009 至该文献
为了确定IL-17+，FOXP3+调节性T细胞产生于外周血中，使用了R&D Systems公司的白介素10酶联免疫吸附试剂盒进行酶联免疫吸附实验。 更多
PLAT
plasminogen activator, tissue
总数:2
Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling. 2008 至该文献
为了阐述锂抑制Smad3/4依赖性的转化生长因子-β-反应基因激活的机理，采用了Santa Cruz公司的tPA抗体进行了蛋白印迹实验。 更多
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
总数:1
Platelet-activating factor acetylhydrolase, and not paraoxonase-1, is the oxidized phospholipid hydrolase of high density lipoprotein particles. 2003 至该文献
肝细胞生长因子 (hepatocyte growth factor)
hepatocyte growth factor (hepapoietin A; scatter factor)
总数:10
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 至该文献
为研究胰岛素生长因子在骨髓瘤细胞生长过程中所发挥的作用，及其受体表达与骨髓瘤患者预后的相关性，将R&D Systems提供的单克隆抗人HGF用于阻断或激活实验中。 更多
白细胞介素1beta (IL-1beta)
interleukin 1, beta
总数:28
Local and systemic responses in matrix metalloproteinase 8-deficient mice during Porphyromonas gingivalis-induced periodontitis. 2009 至该文献
为了研究牙龈卟啉单胞菌所致牙周炎中基质金属蛋白酶8的作用，在免疫染色试验中将R&D Systems的interleukin-1β作用于石蜡包被的组织样品上。 更多
APOC3
apolipoprotein C-III
总数:3
Apolipoprotein B in cholesterol-containing drusen and basal deposits of human eyes with age-related maculopathy. 2003 至该文献
IL1RN
interleukin 1 receptor antagonist
总数:1
Beta-(1-->3)-D-glucan modulates DNA binding of nuclear factors kappaB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1beta/IL-1 receptor antagonist ratio. 2006 至该文献