肿瘤转移
基因
试剂
文献样例
产品评述样例
AMFR
autocrine motility factor receptor
S100A4
S100 calcium binding protein A4
总数:5
Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration. 2008 至该文献
CD82
CD82 molecule
总数:5
KAI1 metastasis suppressor protein is down-regulated during the progression of human endometrial cancer. 2003 至该文献
NME1
non-metastatic cells 1, protein (NM23A) expressed in
总数:10
Clinical significance of intracytoplasmic nm23-H1 expression in diffuse large B-cell lymphoma. 2004 至该文献
BRMS1
breast cancer metastasis suppressor 1
总数:1
Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis. 2006 至该文献
c-Met
met proto-oncogene (hepatocyte growth factor receptor)
总数:30
Progesterone receptor A and c-Met mediates spheroids-endometrium attachment. 2009 至该文献
为了研究孕激素受体A和c-Met对子宫内膜的作用,采用了Santa Cruz的抗c-Met抗体进行免疫印迹试验。 更多
趋化因子受体4 (CXCR4)
chemokine (C-X-C motif) receptor 4
总数:38
Constitutive Expression of the alpha(4) Integrin Correlates with Tumorigenicity and Lymph Node Metastasis of the B16 Murine Melanoma. 2010 至该文献
为了研究alpha 4 整合素蛋白在小鼠黑素瘤细胞的肿瘤发生及转移中所起的作用,使用了AnaSpec公司的抗CXCR-4抗体来进行蛋白印迹分析。 更多
PRL 3
protein tyrosine phosphatase type IVA, member 3
HER2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
总数:82
HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy. 2009 至该文献
为了揭示BIBW2992和rapamycin联合治疗是具有HER2突变表达的肺腺鳞癌最有效的治疗方案,使用了Cell Signaling Technology公司的抗磷酸化HER2抗体进行免疫组化。 更多
E钙粘蛋白 (E-cadherin)
cadherin 1, type 1, E-cadherin (epithelial)
总数:143
Exploring the Gain of Function Contribution of AKT to Mammary Tumorigenesis in Mouse Models. 2010 至该文献
为了研究AKT对于乳腺肿瘤的发生的作用,使用了BD Transduction Laboratories公司的抗E-钙粘素抗体进行免疫组化实验。 更多
Ras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
总数:20
Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity. 2009 至该文献
为了研究Prdx1在调控肿瘤发生中的作用,采用了Oncogene公司的抗Ras抗体产品,进行了免疫印迹实验。 更多
FAK
PTK2 protein tyrosine kinase 2
总数:111
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression. 2010 至该文献
为了研究活化状态的p42/44和p38在MMP-13表达中的作用,采用了Santa Cruz Biotechnology公司的兔单克隆FAK抗体(1:1000)和磷酸化的FAK抗体(1:500),进行了蛋白质印迹实验。 更多
HUNK
hormonally up-regulated Neu-associated kinase
TGF-beta1
transforming growth factor, beta 1
总数:58
Contrasting roles for all-trans retinoic acid in TGF-beta-mediated induction of Foxp3 and Il10 genes in developing regulatory T cells. 2009 至该文献
在T细胞发育调节过程中,为了阐明全反式维甲酸对TGF-β-诱导调节的Foxp3和Il10基因的截然相反的作用,采用了R&D Systems的人重组TGF-β1 进行流式细胞试验。 更多
MMP-2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
总数:54
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. 2009 至该文献
为了研究MMP2表达在人胰腺细胞系BxPC-3的浸润及黏附中的作用,采用了Santa Cruz公司的MMP-2单克隆抗体用于免疫印迹实验。 更多
uPA
plasminogen activator, urokinase
总数:13
Multiple cellular mechanisms related to cyclin A1 in prostate cancer invasion and metastasis. 2008 至该文献
DACH1
dachshund homolog 1 (Drosophila)
β1整合素 (beta1 integrin)
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
总数:95
Disruption of Smad4 in mouse epidermis leads to depletion of follicle stem cells. 2009 至该文献
为了研究Smad4在卵泡干细胞的维持中的作用,使用了Santa Cruz Biotechnology公司的β1-整合素抗体来进行蛋白印迹实验。 更多
CD44
CD44 molecule (Indian blood group)
总数:69
MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization. 2009 至该文献
为了研究MT1-MMP和RECK在人造血祖细胞的移动,粘附和动员中的作用,使用了Serotec公司的抗人CD44抗体进行流式细胞术实验。 更多
CLEC9A
C-type lectin domain family 9, member A
CXCL12
chemokine (C-X-C motif) ligand 12
总数:17
Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells. 2009 至该文献
为了证实蒽环霉素可以抑制HIF-1的转录表达以及肿瘤引起的血管生成细胞的动员,使用了R&D Systems公司的SDF-1α ELISA来分析SDF-1α的浓度。 更多
Tiam1
T-cell lymphoma invasion and metastasis 1
总数:6
HGF attenuates thrombin-induced endothelial permeability by Tiam1-mediated activation of the Rac pathway and by Tiam1/Rac-dependent inhibition of the Rho pathway. 2007 至该文献
为研究Rac-GTP酶和 Rac特异的核苷酸交换因子 Tiam1在EC起防护屏障机制中的作用,采用Santa Cruz 生产的T淋巴瘤侵袭转移诱导因子1(Tiam 1)抗体用于免疫印迹实验。 更多
snail 1锌指蛋白 (SNAI1)
snail homolog 1 (Drosophila)
总数:6
Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma. 2009 至该文献
为了研究snail1介导的肿瘤抑制因子的下调表达在黑素瘤中所起的作用,使用了Santa Cruz公司的抗Snail1抗体来进行ChIP分析。 更多
uPAR
plasminogen activator, urokinase receptor
总数:12
Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model. 2008 至该文献
使用了Santa Cruz生物公司的抗uPAR抗体进行免疫印迹实验来评估水飞蓟宾阶段特异性PCa化学防治效果,并开发各阶段均有确定特征的TRAMP模型的有效性。 更多
MMP-9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
总数:51
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. 2009 至该文献
为了研究蛋白激酶D1抑制乳腺肿瘤细胞侵袭的机制,采用了Epitomics公司的抗MMP-9抗体,进行了免疫组织化学实验。 更多
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
总数:14
Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction. 2009 至该文献
为研究心梗之后SPARC在维持心脏ECM的完整方面所起的作用,使用了R&D systems公司的抗SPARC抗体来进行蛋白印迹分析。 更多
RhoC
ras homolog gene family, member C
总数:4
WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer. 2004 至该文献
Sigma的兔抗RhoC多克隆抗体被用于蛋白质印迹实验,来研究RhoC和WISP3在乳腺癌发展过程中的作用。 更多
EphA2
EPH receptor A2
总数:19
EphA2 as a novel molecular marker and target in glioblastoma multiforme. 2005 至该文献
Grb2
growth factor receptor-bound protein 2
总数:45
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 2009 至该文献
为了说明PAX 5可以在小肺癌细胞中表达并能调控c-Met的转录,使用了Santa Cruz Biotechnology公司的兔抗Ron-β多克隆抗体进行蛋白印迹实验。 更多
fascin
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
总数:5
Effect of roflumilast on inflammatory cells in the lungs of cigarette smoke-exposed mice. 2008 至该文献
RON
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
总数:6
The RON receptor tyrosine kinase promotes MSP-independent cell spreading and survival in breast epithelial cells. 2009 至该文献
为了研究RON受体酪氨酸激酶在乳腺上皮细胞中的致瘤性,使用了R&D Systems公司的抗MSP受体抗体来进行免疫沉淀。 更多
beta 连环蛋白 (beta-catenin)
catenin (cadherin-associated protein), beta 1, 88kDa
总数:186
Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice. 2010 至该文献
为了研究N-WASP在调控SIRT1的活性和高脂饮食诱发的小鼠脂肪肝中的作用,采用了Sigma-Aldrich公司的抗beta-catenin抗体产品,进行了免疫印迹实验。 更多
ezrin
总数:30
Participation of ezrin in bacterial uptake by trophoblast giant cells. 2009 至该文献
为了研究埃兹蛋白在细菌通过滋养层巨细胞入侵的过程中所起的作用,使用了EPITOMICS公司的抗埃兹蛋白抗体来进行蛋白印迹分析。 更多
表皮生长因子受体 (EGFR)
epidermal growth factor receptor
总数:157
Bone morphogenetic protein 4 stimulates neuronal differentiation of neuronal stem cells through the ERK pathway. 2009 至该文献
为了研究BMP4在神经干细胞分化形成神经元过程中所起的作用,使用了Cell Signaling Biotechnology公司的抗EGFR的抗体来进行免疫印迹分析。 更多
p53
tumor protein p53
总数:249
Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation. 2010 至该文献
为了研究二苯甲脒衍生物喷他脒可以抑制组蛋白H2A乙酰化并最终抑制DNA损伤反应的机制使用了Cell Signaling Technology公司的小鼠单克隆磷酸化p53抗体进行免疫印迹实验。 更多
RHOD
ras homolog gene family, member D
总数:3
Plasma membrane-associated sialidase is up-regulated in renal cell carcinoma and promotes interleukin-6-induced apoptosis suppression and cell motility. 2006 至该文献
GPI
glucose-6-phosphate isomerase
总数:2
Leprosy & gangrene: a rare association; role of anti phospholipid antibodies.. 2005 至该文献
血管内皮生长因子 (VEGF)
vascular endothelial growth factor A
总数:105
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2010 至该文献
为了研究mPGES-1在调控肿瘤生长、侵润和转移中的作用,采用了Sigma公司的抗VEGF抗体产品,进行了免疫印迹实验。 更多
PEBP1
phosphatidylethanolamine binding protein 1
总数:4
Use of cancer-specific yeast-secreted in vivo biotinylated recombinant antibodies for serum biomarker discovery. 2008 至该文献
为了形成发现卵巢癌循环蛋白标记的方法,采用Abgent公司的PEBP1抗体,进行蛋白质印迹实验。 更多
ZEB1
zinc finger E-box binding homeobox 1
总数:4
ZEB-1, a repressor of the semaphorin 3F tumor suppressor gene in lung cancer cells. 2009 至该文献
为了说明在肺癌细胞中ZEB-1可以抑制臂板蛋白3F肿瘤抑制基因,使用了Santa Cruz Biotechnology公司的抗ZEB-1抗体进行蛋白印迹实验。 更多
KiSS 1
KiSS-1 metastasis-suppressor
总数:5
Large isoform of MRJ (DNAJB6) reduces malignant activity of breast cancer. 2008 至该文献
Src
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
总数:147
S100B Protein Regulates Astrocyte Shape and Migration via Interaction with Src Kinase: IMPLICATIONS FOR ASTROCYTE DEVELOPMENT, ACTIVATION, AND TUMOR GROWTH. 2009 至该文献
为了研究S100B蛋白在星形胶质细胞成形和迁移过程中所起的调控作用,使用了Cell Signaling公司的抗Src抗体来进行蛋白印迹分析。 更多
WNT5A
wingless-type MMTV integration site family, member 5A
总数:3
Mutations in the C-terminus of the X protein of hepatitis B virus regulate Wnt-5a expression in hepatoma Huh7 cells: cDNA microarray and proteomic analyses. 2008 至该文献
Wnt-5a抗体(R&D)可用于免疫印迹实验,来研究乙型肝炎病毒X蛋白(HBx)的分子生物学功能。 更多
MT1-MMP
matrix metallopeptidase 14 (membrane-inserted)
总数:15
A drosophila model for EGFR-Ras and PI3K-dependent human glioma. 2009 至该文献
为了研究神经胶质瘤中EGFR和3磷脂酰肌醇激酶信号途径所起的作用,使用了DSHB公司的抗dMMP1抗体来进行免疫组化分析。 更多
WNT10B
wingless-type MMTV integration site family, member 10B
总数:2
NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation. 2010 至该文献
为了研究NF-E2在调控ROS累积和巨核细胞成熟中的作用,采用了Santa Cruz Biotechnology公司的抗CD61抗体产品,进行了免疫沉淀实验。 更多
heparanase
总数:6
Involvement of heparanase in migration of microglial cells. 2008 至该文献
DAL 1
erythrocyte membrane protein band 4.1-like 3
总数:2
The tumor suppressor DAL-1/4.1B and protein methylation cooperate in inducing apoptosis in MCF-7 breast cancer cells.. 2006 至该文献
Upstate公司生产的DAL-1/4.1B 抗体可用于免疫印迹实验,来研究乳腺癌细胞系MCF-7的凋亡机制。 更多
Akt
v-akt murine thymoma viral oncogene homolog 1
总数:475
Quantitative in situ detection of phosphoproteins in fixed tissues using quantum dot technology. 2009 至该文献
为了考察量子点技术在准确定量原位分析组织中蛋白磷酸化水平在临床研究中的作用,利用cell Signaling Technology 公司的anti-pAKT (S473) (736E11)抗体进行免疫组化分析和蛋白质印迹分析小鼠组织中AKT 磷酸化水平。 更多
肝细胞生长因子 (hepatocyte growth factor)
hepatocyte growth factor (hepapoietin A; scatter factor)
总数:14
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 至该文献
为研究胰岛素生长因子在骨髓瘤细胞生长过程中所发挥的作用,及其受体表达与骨髓瘤患者预后的相关性,将R&D Systems提供的单克隆抗人HGF用于阻断或激活实验中。 更多
Ras相关C3肉毒杆菌毒素底物1 (Rac1)
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
总数:63
The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion. 2009 至该文献
为了研究芳香烃受体对组成性的Vav3表达以及细胞可塑性和迁移的调节,使用了Cell Signaling Technology公司的抗Rac1抗体来进行免疫印迹分析。 更多
p120ctn
catenin (cadherin-associated protein), delta 1
总数:24
Overexpression of CD97 in intestinal epithelial cells of transgenic mice attenuates colitis by strengthening adherens junctions. 2010 至该文献
为了研究CD97在肠上皮细胞中的功能,采用了Santa Cruz公司的兔多克隆p120连环蛋白抗体,进行了蛋白质印迹实验。 更多
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
总数:2
Mxi2 promotes stimulus-independent ERK nuclear translocation. 2007 至该文献
为了证明Mxi2对核细胞中erk1/2核与质的分布,及提高他们的蓄积有着极深的影响,使用了Santa Cruz公司的兔多克隆抗Rho-GDI抗体,进行了免疫印迹实验。 更多
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
总数:2
Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1. 2009 至该文献
为了研究c-Raf-1诱导的肺发育不良转化为肺恶性腺瘤的分子机制,使用了Santa Cruz公司的抗Reck抗体来进行免疫组化分析。 更多
caveolin-1
caveolin 1, caveolae protein, 22kDa
总数:71
Xp11.2 translocation renal cell carcinoma occurring during pregnancy with a novel translocation involving chromosome 19: a case report with review of the literature. 2009 至该文献
为了说明19号染色体的易位可能会引起Xp11.2易位相关的肾细胞癌,使用了Epitomics公司的抗calveolin-1抗体进行免疫组化实验。 更多
Ezh2
enhancer of zeste homolog 2 (Drosophila)
总数:8
Huntingtin facilitates polycomb repressive complex 2. 2010 至该文献
为了阐明huntingtin的α螺旋组成的全长和其促进多亚基PRC2复合体的作用,实验使用了BD Transduction labs公司的抗Ezh2抗体进行免疫细胞化学。 更多
runt相关转录因子2 (RUNX2)
runt-related transcription factor 2
总数:20
Juvenile dermatomyositis calcifications selectively displayed markers of bone formation. 2009 至该文献
为了测定在幼年皮肌炎病理性钙化中SIBLING蛋白和骨组分的存在,使用了R&D Systems公司的抗Cbfa1抗体来进行免疫组化实验。 更多
弹性蛋白 (vimentin)
总数:80
TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. 2010 至该文献
为了研究TGFB1在调控Mdm2的表达和乳腺癌晚期转移中的作用,采用了Santa Cruz Biotechnology Inc公司的抗Vimentin抗体产品,进行了免疫印迹实验 更多
S100A6
S100 calcium binding protein A6
总数:6
Up-regulation, modification, and translocation of S100A6 induced by exposure to ionizing radiation revealed by proteomics profiling. 2007 至该文献
为了记录进行离子化放射后结肠癌和肺癌细胞中S100A6蛋白水平的增加,使用了Sigma-Aldrich 公司的S100A6抗体,进行了免疫印迹实验。 更多
Smad3
SMAD family member 3
总数:48
Overlapping promoter targeting by Elk-1 and other divergent ETS-domain transcription factor family members. 2009 至该文献
为了研究TGFβ在调节神经细胞发育过程中的功能,使用了Santa Cruz Biotechnology公司的小鼠抗Smad3抗体来进行免疫荧光实验。 更多
YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
总数:12
Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest. 2008 至该文献
14-3-3β抗体以1/1000稀释,进行蛋白质印迹实验。 更多
B-Raf
v-raf murine sarcoma viral oncogene homolog B1
总数:10
Development of polycystic kidney disease in juvenile cystic kidney mice: insights into pathogenesis, ciliary abnormalities, and common features with human disease. 2006 至该文献
在western blot实验中使用了Cell Signalling Technology公司的抗B-Raf 抗体来研究未成年小鼠的囊肾中产生的多囊肾病,进一步观察其发病机理、纤毛异常以及同人疾病的共同点。 更多
Flt-1
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
总数:16
Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model. 2008 至该文献
使用了Santa Cruz生物公司的抗VEGF-R1抗体进行免疫印迹实验来评估水飞蓟宾阶段特异性PCa化学防治效果,并开发各阶段均有确定特征的TRAMP模型的有效性。 更多
AKT2
v-akt murine thymoma viral oncogene homolog 2
总数:20
Activation of Wnt/beta-Catenin Signaling Increases Insulin Sensitivity through a Reciprocal Regulation of Wnt10b and SREBP-1c in Skeletal Muscle Cells. 2009 至该文献
为了研究在骨骼肌细胞中β-连环蛋白信号的活化能够提高对胰岛素的敏感性的机制,采用了Cell Signaling公司的兔单克隆Akt2抗体和磷酸化的Akt2抗体,进行了蛋白质印记实验。 更多
粘蛋白1 (MUC1)
mucin 1, cell surface associated
总数:24
Xp11.2 translocation renal cell carcinoma occurring during pregnancy with a novel translocation involving chromosome 19: a case report with review of the literature. 2009 至该文献
为了说明19号染色体的易位可能会引起Xp11.2易位相关的肾细胞癌,使用了Ventana Medical Systems公司的抗上皮膜抗原的抗体进行免疫组化实验。 更多
lysyl oxidase
总数:2
T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice. 2009 至该文献
使用Novus Biologicals兔多克隆抗LOX抗体来阻断和培育蛋白印记,来证明T细胞激活会阻止动脉粥样斑块中胶原的成熟。 更多
beta 肌动蛋白 (beta-actin)
actin, beta
总数:190
An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia. 2009 至该文献
为了研究缺氧诱导因子1在对氧流量的转录反应中的重要作用,使用了Sigma公司的β actin抗体,进行了免疫印迹实验。 更多
HIF-1 alpha
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
总数:68
Characterization of the Activation of Protein Tyrosine Phosphatase, Receptor-Type, Z Polypeptide 1 (PTPRZ1) by Hypoxia Inducible Factor-2 Alpha. 2010 至该文献
为了研究PTPRZ1启动子上HIF结合及Ets结合的基序并且说明了HIF-2可以激活PTPRZ1,使用了Novus Biologicals公司的HIF1alpha抗体进行染色质免疫沉淀实验。 更多
OPN
secreted phosphoprotein 1
总数:20
RANKL, osteopontin, and osteoclast homeostasis in a hyperocclusion mouse model. 2008 至该文献
利用高咬合小鼠模型,为了研究咬合力的作用、RANK和LOPN对牙周韧带稳态的影响,采用了Santa Cruz的抗骨桥蛋白单抗,进行免疫组化实验 更多
TWIST1
twist homolog 1 (Drosophila)
总数:1
Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma. 2009 至该文献
为了研究snail1介导的肿瘤抑制因子的下调表达在黑素瘤中所起的作用,使用了Abcam公司的抗Twist抗体来进行蛋白印迹分析。
N acetylglucosaminyltransferase V
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
总数:1
N-acetylglucosaminyltransferase V and beta1-6 branching N-linked oligosaccharides are associated with good prognosis of patients with bladder cancer. 2006 至该文献
maspin
serpin peptidase inhibitor, clade B (ovalbumin), member 5
总数:8
Epigenetic silencing of maspin expression occurs early in the conversion of keratocytes to fibroblasts. 2008 至该文献
Oncogene Research公司生产的兔抗人maspin多克隆抗体可用于免疫组化实验,来研究maspin 启动子区DNA甲基化及组蛋白H3去甲基化是否是人角膜间质成纤维细胞和肌成纤维细胞中maspin基因表达下调的机制。 更多
EGF
epidermal growth factor
总数:32
Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin. 2009 至该文献
为了研究aprataxin在Tdp1缺失的小鼠原代神经细胞的染色体单链断裂修复过程中的功能,使用了Sigma公司的EGF蛋白来培养小鼠原代星形胶质细胞。 更多
HPN
hepsin
总数:2
Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture. 2006 至该文献
p130Cas
breast cancer anti-estrogen resistance 1
总数:15
The neurofibromatosis 2 protein, merlin, regulates glial cell growth in an ErbB2- and Src-dependent manner. 2009 至该文献
为了研究Merlin对神经胶质细胞生长的影响,采用了Sigma公司的p130CAS抗体进行蛋白印迹实验。 更多
SCGB2A2
secretoglobin, family 2A, member 2
总数:1
Mammaglobin and CRxA-01 in pleural effusion cytology: potential utility of distinguishing metastatic breast carcinomas from other cytokeratin 7-positive/cytokeratin 20-negative carcinomas. 2004 至该文献
PP2AC
protein phosphatase 2, catalytic subunit, alpha isozyme
总数:27
Regional hippocampal differences in AKT survival signaling across the lifespan: implications for CA1 vulnerability with aging. 2009 至该文献
为了阐明活化AKT在海马受损中的作用,实验使用了Cell Signaling公司的抗PP2A-A抗体进行免疫印迹。 更多
ENO1
enolase 1, (alpha)
总数:2
Proteomic analysis of low dose arsenic and ionizing radiation exposure on keratinocytes. 2009 至该文献
为了研究经低剂量砒霜和电离辐射处理后的角质细胞的蛋白质组,使用了Santa Cruz公司的抗alpha烯醇酶抗体来进行蛋白印迹分析。 更多
VEGF-C
vascular endothelial growth factor C
总数:9
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 至该文献
为了研究HT-29细胞中姜黄色素在过氧化物酶体增殖因子活化受体δ(PPARδ)和相关基因表达中的作用,采用了Epitomics公司的抗VEGF抗体(1:1000),进行了蛋白质印迹实验。 更多
LKB1
serine/threonine kinase 11
总数:6
eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy. 2008 至该文献
为了研究eIF4GI在调控细胞增殖和自噬中的作用,采用Cell Signaling Technology公司的兔抗AMPKalpha抗体产品,进行了免疫印迹实验。 更多
LIMK1
LIM domain kinase 1
总数:5
Loss of modifier of cell adhesion reveals a pathway leading to axonal degeneration. 2009 至该文献
为了研究MOCA在维持轴突的功能完整上的作用,使用了Cell Signaling Technology公司的LIMK1和磷酸化LIMK1抗体进行蛋白印迹实验。 更多
RANKL
tumor necrosis factor (ligand) superfamily, member 11
总数:14
High-mobility group box proteins modulate tumor necrosis factor-alpha expression in osteoclastogenesis via a novel deoxyribonucleic acid sequence. 2008 至该文献
为了研究高迁移率组框蛋白在肿瘤坏死因子-α通过新脱氧核糖核酸序列表达的骨细胞生成中的作用,采用Sigma-Aldrich重组体人类RANKL,进行细胞处理实验。 更多
JAM3
junctional adhesion molecule 3
ETV4
ets variant 4
总数:4
Putative regulation of expression of members of the Ets variant 4 transcription factor family and their downstream targets in the rat epididymis. 2006 至该文献
Annexin I
annexin A1
总数:9
Short-term heat exposure inhibits inflammation by abrogating recruitment of and nuclear factor-{kappa}B activation in neutrophils exposed to chemotactic cytokines. 2008 至该文献
为了验证假说:在患有皮肤炎症的小鼠模型上,把老鼠置于发烧样温度环境中,会使中性粒细胞募集和NF-κB活化丧失,采用了Calbiochem公司的annexin I刺激细胞。 更多
CD147
basigin (Ok blood group)
总数:15
Upregulation of EMMPRIN after permanent focal cerebral ischemia. 2008 至该文献
为了检测细胞外基质金属蛋白酶诱导因子和MMP-9 expre的潜在性联系,采用了Serotec公司的大鼠抗细胞外基质金属蛋白酶诱导因子单克隆抗体(1:200)进行了免疫组化实验。 更多
RhoA
ras homolog gene family, member A
总数:47
The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion. 2009 至该文献
为了研究芳香烃受体对组成性Vav3表达以及细胞可塑性和迁移的调节,使用了Cell Signaling Technology公司的抗RhoA抗体来进行免疫印迹分析。 更多
Sp1转录因子 (Sp1)
Sp1 transcription factor
总数:73
Heparanase regulates levels of syndecan-1 in the nucleus. 2009 至该文献
为了说明肝素酶能促进多配体聚糖-1在细胞核中的表达,在进行蛋白印迹实验时使用了Santa Cruz Biotechnology公司的抗SP1抗体。 更多
ACTN4
actinin, alpha 4
总数:4
Carbachol regulation of rabbit ileal brush border Na+-H+ exchanger 3 (NHE3) occurs through changes in NHE3 trafficking and complex formation and is Src dependent. 2004 至该文献
DR4
tumor necrosis factor receptor superfamily, member 10a
总数:7
A study of TRAIL receptors in squamous cell carcinoma of the head and neck. 2005 至该文献
为研究肿瘤坏死因子相关凋亡诱导配体1(TRAIL-R1)和肿瘤坏死因子相关凋亡诱导配体2(TRAIL-R2)可能的拮抗作用,采用R&D 公司生产的 TRAIL-R1抗体用于免疫组化实验。 更多
MEKK1
mitogen-activated protein kinase kinase kinase 1
总数:16
A shared mechanism of adhesion modulation for tenascin-C and fibulin-1. 2009 至该文献
Sigma-Aldrich MAP单抗用于免疫印迹用来证明fibulin-1抑制纤维细胞扩散和细胞介导纤维基质收缩 更多