p75 NTR receptor-mediated signalling
基因
试剂
文献样例
产品评述样例
14 3 3 protein epsilon
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
总数:5
Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor. 2009 至该文献
为了研究HT-29细胞中姜黄色素在过氧化物酶体增殖因子活化受体δ(PPARδ)和相关基因表达中的作用,采用了Santa Cruz Biotechnology公司的抗14-3-3epsilon抗体(1:2000),进行了蛋白质印迹实验。 更多
ADAM金属肽酶成员17 (ADAM17)
ADAM metallopeptidase domain 17
总数:13
TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. 2008 至该文献
为了证明TACE在结肠直肠癌细胞中可以抑制EGFR通路,采用了Santa Cruz Biotechnology的抗TACE抗体进行了免疫印迹实验。 更多
APH1B
aph-1 homolog B, gamma-secretase subunit
ARHGAP4
Rho GTPase activating protein 4
总数:3
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. 2008 至该文献
ARHGEF18
Rho/Rac guanine nucleotide exchange factor 18
ARHGEF7
Rho guanine nucleotide exchange factor 7
总数:1
GM130-dependent control of Cdc42 activity at the Golgi regulates centrosome organization. 2009 至该文献
使用Santa Cruz生物公司的抗-β-PIX 抗体进行免疫印迹实验来研究高尔基体的GM130依赖的Cdc42活性在调节中心体重组过程中的作用。
ARHGEF9
Cdc42 guanine nucleotide exchange factor 9
BAD
BCL2 associated agonist of cell death
总数:49
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. 2011 至该文献
为了研究切割的NIK 导致非经典的NF- kB 活性,采用了Cell Signaling Technology的抗BAD抗体进行免疫印迹试验。 更多
Bim
BCL2 like 11
总数:31
Control of cellular Bcl-xL levels by deamidation-regulated degradation. 2013 至该文献
为了研究脱酰胺过程对Bcl-xL降解的调控作用,Calbiochem的抗Bim抗体被用于进行免疫沉淀实验。 更多
胱氨酸-天冬氨酸蛋白酶2 (caspase-2)
caspase 2
总数:9
Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI. 2008 至该文献
使用Santa Cruz公司的Caspase-2抗体进行免疫印迹实验来分析用蛋白酶体抑制剂PSI处理前髓细胞性白血病细胞系 HL-60后的亚蛋白质组变化。 更多
胱氨酸-天冬氨酸蛋白酶3 (caspase-3)
caspase 3
总数:212
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. 2012 至该文献
为了研究噻苯咪唑对人体细胞增殖和细胞凋亡的影响,采用了艾碧康生物公司的抗半胱氨酸天冬氨酸蛋白酶3抗体进行免疫组织化学试验。 更多
ECT2
epithelial cell transforming 2
总数:2
CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase. 2009 至该文献
使用Santa Cruz生物公司的抗Ect2抗体进行免疫印迹来研究细胞周期过程中调钙素调节Ect2, MgcRacGAP, 和 MKLP1 表达的作用 更多
FGD1
FYVE, RhoGEF and PH domain containing 1
FGD2
FYVE, RhoGEF and PH domain containing 2
FGD4
FYVE, RhoGEF and PH domain containing 4
GRF2
Ras protein specific guanine nucleotide releasing factor 2
HDAC1
histone deacetylase 1
总数:54
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 2010 至该文献
为了说明IRF5同HATs和HDACs一起调控促炎细胞因子的转录水平表达,使用了Upstate Biotechnology公司的抗HDAC1抗体进行蛋白印迹实验。 更多
HDAC2
histone deacetylase 2
总数:24
High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo. 2009 至该文献
为了研究胰脏癌中HDAC的活性与RelA/p65的活化之间的联系,使用了Abcam公司的抗HDAC2抗体来进行免疫组化分析。 更多
HDAC3
histone deacetylase 3
总数:21
Histone deacetylase complexes promote trinucleotide repeat expansions. 2012 至该文献
为了鉴定能够促进三核苷酸重复序列扩增的新组蛋白脱乙酰酶复合物,采用了Santa Cruz Biotechnology公司抗组蛋白脱乙酰酶3抗体进行了免疫印迹实验。 更多
IkappaBalpha
NFKB inhibitor alpha
总数:117
Inhibition of NF-?B signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. 2010 至该文献
为了研究EPEC蛋白NleE在人类树突细胞中抑制NF-kappa B信号通路的作用,采用了Santa Cruz公司抗I-kappa B alpha抗体进行了免疫印记实验。 更多
IKKbeta
inhibitor of nuclear factor kappa B kinase subunit beta
总数:36
A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. 2013 至该文献
为了研究人类IKK2激活的结构基础,Millipore的抗IKK2抗体被用于进行蛋白质免疫印迹实验。 更多
IRAK
interleukin 1 receptor associated kinase 1
总数:10
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 至该文献
为了研究IRAK-1信号阻断对TLR2和TLR4诱导的人树突状细胞耐受有重要作用,采用Santa Cruz的鼠抗IRAK-1抗体进行蛋白印迹实验。 更多
JNK
mitogen-activated protein kinase 8
总数:193
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 至该文献
为了研究在B细胞中TNIK在经典的NF-kB和JNK通路中扮演何种角色及如何发挥这种作用,采用了Santa Cruz Biotechnology的JNK1抗体进行免疫印迹实验。 更多
LINGO1
leucine rich repeat and Ig domain containing 1
MAGED1
MAGE family member D1
总数:1
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. 2010 至该文献
为了研究NRAGE在调节NF-kappaB活性时所发挥的作用,采用了Santa Cruz的羊抗NRAGE抗体进行蛋白质印迹试验。
MCF2
MCF.2 cell line derived transforming sequence
总数:1
Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1. 2008 至该文献
为了证明Nm23-H1可以通过调节Dbl1的活性负调控细胞迁移和肿瘤转移,采用了Santa Cruz兔抗Dbl-1抗体进行了免疫沉淀和免疫印记实验。
MCF2L
MCF.2 cell line derived transforming sequence like
MYD88
MYD88 innate immune signal transduction adaptor
总数:3
Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state. 2008 至该文献
为了研究1型糖尿病人单核细胞中TLR2和TLR4的表达,采用eBiosciences公司兔抗MyD88抗体进行免疫印迹实验。 更多
髓鞘相关糖蛋白 (myelin associated glycoprotein)
总数:3
Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes. 2010 至该文献
为了研究Nkx2.2和Nkx6.2在调节髓鞘形成中的作用,采用了Chemicon公司的鼠抗MAG抗体产品(1:5000),进行了免疫荧光实验。 更多
NET1
neuroepithelial cell transforming 1
总数:1
The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion. 2009 至该文献
为了研究芳香烃受体对组成性的Vav3表达以及细胞可塑性和迁移的调节,使用了Santa Cruz Biotechnology公司的抗Net1抗体来进行免疫印迹分析。
NGEF
neuronal guanine nucleotide exchange factor
神经生长因子 (NGF)
nerve growth factor
总数:2
NGF and BDNF signaling control amyloidogenic route and Abeta production in hippocampal neurons. 2008 至该文献
为了研究神经生长因子和脑源性神经营养因子在神经元的凋亡性死亡中的作用,采用Novus公司的单克隆抗NGF抗体(30 μg/ml),进行细胞培养实验。 更多
nicastrin
总数:10
Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin. 2008 至该文献
为了研究TNF-α对γ-分泌酶中作用,采用了Calbiochem公司的兔抗nicastrin抗体进行免疫印迹实验。 更多
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
p50
nuclear factor kappa B subunit 1
总数:81
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 2010 至该文献
为了说明流感病毒感染期间IL-32表达水平的提高抑制病毒的复制,使用了Santa Cruz Biotechnology公司的anti-p50抗体来进行染色质免疫共沉淀实验。 更多
p65
RELA proto-oncogene, NF-kB subunit
总数:146
DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. 2012 至该文献
为了研究DNA依赖的蛋白激酶在IRF-3依赖的先天性免疫反应中的作用,采用了Santa Cruz的抗p65抗体进行了细胞免疫荧光实验。 更多
p75NTR
nerve growth factor receptor
总数:17
Repeated exposure to acid and bile selectively induces colonic phenotype expression in a heterogeneous Barrett's epithelial cell line. 2008 至该文献
为了说明Barrett上皮细胞系在暴露于酸和胆汁盐后可以发生细胞表型的改变,使用了Novus Biologicals公司的抗p75NTR抗体来进行免疫细胞化学实验。 更多
PLEKHG2
pleckstrin homology and RhoGEF domain containing G2
PLEKHG5
pleckstrin homology and RhoGEF domain containing G5
Ras相关C3肉毒杆菌毒素底物1 (Rac1)
Rac family small GTPase 1
总数:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 至该文献
为研究RhoGDI2通过Rho GTPases抑制代谢的作用,采用了Millipore公司的抗Rac1单克隆抗体(1:1,000)进行免疫印迹试验。 更多
RhoA
ras homolog family member A
总数:49
Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo. 2010 至该文献
为了研究沉默RhoA和RhoC的表达对人类结直肠癌体内生长的影响,采用Santa Cruz公司的抗RhoA抗体进行了免疫组织化学实验。 更多
RhoGDI
Rho GDP dissociation inhibitor alpha
总数:8
Clues to CD2-associated protein involvement in cytokinesis. 2005 至该文献
RPS27A
ribosomal protein S27a
总数:5
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. 2009 至该文献
为了在内质网相关蛋白的降解途径(ERAD)中鉴定一种新的erasin-ubiquilin-p97/VCP复合体以及其功能,使用了Santa Cruz Biotechnology公司的抗体ubiquitin来进行免疫印迹分析。 更多
RTN4
reticulon 4
总数:2
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 至该文献
为了研究突触的可塑性,采用了Bianca的抗Nogo-A/B的抗体进行了免疫印迹实验。 更多
SORCS3
sortilin related VPS10 domain containing receptor 3
Sos
SOS Ras/Rac guanine nucleotide exchange factor 1
总数:11
Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. 2007 至该文献
Santa Cruz的兔Sos-1抗体被用于蛋白质印迹实验,来研究Abi-1在形态发生和突触形成中的作用。 更多
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2
总数:1
The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis. 2005 至该文献
泛肽结合蛋白p62 (SQSTM1)
sequestosome 1
总数:14
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 至该文献
为了研究具有分解代谢功能的细胞器和具有合成代谢功能的细胞器二者在空间上的结合在促进分泌蛋白合成中的作用,采用Santa Cruz的抗p62抗体进行免疫细胞化学试验。 更多
Tiam1
TIAM Rac1 associated GEF 1
总数:6
Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells. 2008 至该文献
为了阐明结肠癌细胞中Rac1与经典Wnt信号通路之间的关系,使用了Santa Cruz Biotechnology公司的Tiam1抗体(C-16)来进行免疫沉淀和染色质沉淀实验。 更多
TRAF6
TNF receptor associated factor 6
总数:17
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 至该文献
为了研究在B细胞中TNIK在经典的NF-kB和JNK通路中扮演何种角色及如何发挥这种作用,采用了Santa Cruz Biotechnology的TRAF6 (H-274)抗体进行免疫印迹实验。 更多
UBC
ubiquitin C
总数:7
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. 2014 至该文献
为了研究突触的可塑性,采用了Enzo Life Sciences的抗Ubiquitin的抗体进行了免疫印迹实验。 更多
泛肽 (ubiquitin)
ubiquitin B
总数:34
BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers. 2009 至该文献
为了阐明BCL6和HB-EGF-CTF相互作用,并且这种相互作用可能会引起细胞周期蛋白D2在人胃癌细胞中表达,采用了Cell Signaling Technology公司的小鼠抗泛素单克隆抗体,进行了蛋白质印迹实验。 更多
VAV3
vav guanine nucleotide exchange factor 3
总数:2
Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer. 2008 至该文献
XPLN
Rho guanine nucleotide exchange factor 3