前列腺肿瘤
基因
试剂
文献样例
产品评述样例
雄激素受体 (androgen receptor)
总数:50
Estrogen receptor-{beta} activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNF{alpha} mediated. 2010 至该文献
为了研究雌激素受体beta激活的凋亡的调节机制和它的拮抗物在癌症治疗中的作用，使用了Santa Cruz Biotechnology公司的抗雄激素受体抗体来进行免疫组化试验。 更多
前列腺特异抗原 (prostate specific antigen)
kallikrein-related peptidase 3
总数:18
Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. 2008 至该文献
ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
TMPRSS2
transmembrane protease, serine 2
MSMB
microseminoprotein, beta-
总数:1
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production. 2007 至该文献
为了研究人间质干细胞转化过程中对氧化磷酸化作用的依赖性，采用Abgent公司的抗PRPS1/2/3抗体进行免疫印迹实验。
NKX3 1
NK3 homeobox 1
LMTK2
lemur tyrosine kinase 2
CTBP2
C-terminal binding protein 2
总数:1
Mechanisms directing the nuclear localization of the CtBP family proteins.. 2006 至该文献
KLK2
kallikrein-related peptidase 2
EHBP1
EH domain binding protein 1
SRD5A2
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
HNF1B
HNF1 homeobox B
总数:5
HNF-1beta regulates transcription of the PKD modifier gene Kif12. 2009 至该文献
为了研究HNF-1beta在调控PKD修饰基因Kif12中的作用，采用了Santa Cruz Biotechnology公司的抗HNF1B抗体产品，进行了免疫印迹实验。 更多
SLC22A3
solute carrier family 22 (extraneuronal monoamine transporter), member 3
DAB2IP
DAB2 interacting protein
RNASEL
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
prostate specific membrane antigen
folate hydrolase (prostate-specific membrane antigen) 1
总数:3
Correlation of primary tumor prostate-specific membrane antigen expression with disease recurrence in prostate cancer. 2003 至该文献
为了研究原发性前列腺特异性的膜抗原与前列腺癌疾病复发的相关性，采用了Medical Systems公司的抗PSMA抗体进行免疫组织化学分析 更多
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
TGM4
transglutaminase 4 (prostate)
磷酸酶张力蛋白同源基因 (PTEN)
phosphatase and tensin homolog
总数:45
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 至该文献
为了说明Skp2参与非p19Arf-p53途径的细胞衰老，使用了Neomarkers公司的PTEN抗体来进行免疫组化实验。 更多
JAZF1
JAZF zinc finger 1
prostein
solute carrier family 45, member 3
prostatic acid phosphatase
acid phosphatase, prostate
总数:2
Clinical and experimental progression of a new model of human prostate cancer and therapeutic approach. 2001 至该文献
ER81
ets variant 1
总数:1
V600EBRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. 2009 至该文献
为了研究BRAF在调控RAF-MEK信号通路中的作用，采用了Abnova公司的抗ETV1抗体产品，进行了免疫印迹实验。
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
ELAC2
elaC homolog 2 (E. coli)
总数:1
How do human cells react to the absence of mitochondrial DNA?. 2009 至该文献
运用ProteinTech公司的抗 ELAC2 抗体，进行免疫印迹实验以研究缺乏线粒体DNA时人细胞的反应性。
TPD52
tumor protein D52
KLK15
kallikrein-related peptidase 15
KLK4
kallikrein-related peptidase 4
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
IGFBP-3
insulin-like growth factor binding protein 3
总数:17
IGFBP3 colocalizes with and regulates hypocretin (orexin). 2009 至该文献
为研究胰岛素样生长因子结合蛋白3与食欲素间的相关性，将Santa Cruz提供的多克隆抗人胰岛素样生长因子结合蛋白3抗体用于蛋白免疫印迹实验中。 更多
FOXA1
forkhead box A1
总数:4
Cellular and molecular origin of circumpapillary dysgenesis of the pigment epithelium. 2009 至该文献
为了研究TEAD1和它的辅助因子YAP65和FOXA2在色素上皮发育不全中的调控作用，使用了Santa Cruz公司的FOXA1抗体，来培养膜，进行了免疫印迹和组织化学实验。 更多
PSCA
prostate stem cell antigen
NCOA4
nuclear receptor coactivator 4
总数:1
Endogenous coactivator ARA70 interacts with estrogen receptor alpha (ERalpha) and modulates the functional ERalpha/androgen receptor interplay in MCF-7 cells. 2005 至该文献
SLC39A1
solute carrier family 39 (zinc transporter), member 1
MSR1
macrophage scavenger receptor 1
Akt
v-akt murine thymoma viral oncogene homolog 1
总数:418
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H?-ATPase.. 2011 至该文献
为了研究泡状H+-ATPase参与到mTOR通路中mTORC1的转位和激活，采用Cell Signaling的抗Akt和抗S473磷酸化Akt抗体进行蛋白印迹实验。 更多
PIM1
pim-1 oncogene
总数:6
KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA. 2009 至该文献
为了研究卡波西肉瘤疱疹病毒（KSHV）的抑制需要Pim-1和Pim2激酶作用，使用Santa Cruz anti-Pim-1抗体进行western blot和免疫沉淀实验。 更多
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
总数:1
Colocalization of P450c17 and cytochrome b5 in androgen-synthesizing tissues of the human. 2004 至该文献
KLK11
kallikrein-related peptidase 11
AMACR
alpha-methylacyl-CoA racemase
总数:3
Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer. 2008 至该文献
为了研究蛋白7和19的表达量能反应肾透明细胞癌中基因组的稳定性及良好的预后，采用了Dako AMACR(13H4)抗体进行了免疫组化实验。 更多
SRD5A1
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
HPN
hepsin
总数:1
Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture. 2006 至该文献
TRPM8
transient receptor potential cation channel, subfamily M, member 8
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
总数:2
Increased nucleotide polymorphic changes in the 5'-untranslated region of delta-catenin (CTNND2) gene in prostate cancer. 2009 至该文献
为了研究delta-catenin在前列腺癌中表达增加的机制，采用了Abcam的兔抗delta-catenin抗体（1:100）进行免疫印迹和免疫组化实验。 更多
CRISP3
cysteine-rich secretory protein 3
PDLIM5
PDZ and LIM domain 5
HOXD3
homeobox D3
TNRC6B
trinucleotide repeat containing 6B
PRKD1
protein kinase D1
总数:15
Protein kinase C zeta. A novel regulator of both phosphorylation and de-phosphorylation of cardiac sarcomeric proteins. 2007 至该文献
为研究PKCζ对调节肌丝蛋白磷酸化和去磷酸化的作用，采用了Abgent公司的抗PKD抗体进行蛋白质印迹试验。 更多
CXCR6
chemokine (C-X-C motif) receptor 6
总数:2
Role of Twist in head and neck carcinoma with lymph node metastasis. 2008 至该文献
为了研究Twist在头颈癌转移中的作用，采用了R&D Systems的抗CXCR6抗体进行免疫组化实验。 更多
TRPV6
transient receptor potential cation channel, subfamily V, member 6
PURA
purine-rich element binding protein A
总数:2
Puralpha and Purbeta collaborate with Sp3 to negatively regulate beta-myosin heavy chain gene expression during skeletal muscle inactivity. 2007 至该文献
HOXB13
homeobox B13
总数:1
Epigenetic silencing of novel tumor suppressors in malignant melanoma. 2006 至该文献
HIF-1 alpha
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
总数:62
Characterization of the Activation of Protein Tyrosine Phosphatase, Receptor-Type, Z Polypeptide 1 (PTPRZ1) by Hypoxia Inducible Factor-2 Alpha. 2010 至该文献
为了研究PTPRZ1启动子上HIF结合及Ets结合的基序并且说明了HIF-2可以激活PTPRZ1，使用了Novus Biologicals公司的HIF1alpha抗体进行染色质免疫沉淀实验。 更多
Egr-1
early growth response 1
总数:26
Transforming growth factor {beta}1-mediated activation of the smooth muscle {alpha}-actin gene in human pulmonary myofibroblasts is inhibited by tumor necrosis factor-{alpha} via mitogen-activated protein kinase kinase 1-dependent Induction of the Egr-1 t. 2009 至该文献
为了研究转化生长因子β1同肿瘤坏死因子a的关系，采用了Santa Cruz Biotechnology公司的C-19兔单克隆Egr-1抗体，进行了蛋白印记实验。 更多
PSAP
prosaposin
SPDEF
SAM pointed domain containing ets transcription factor
matriptase
suppression of tumorigenicity 14 (colon carcinoma)
p27
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
总数:116
Cyclin K and cyclin D1b are oncogenic in myeloma cells. 2010 至该文献
为了研究多发性骨髓瘤中细胞周期蛋白K和细胞周期蛋白D1b的作用，采用了Santa Cruz的抗p27Kip1和抗磷酸化p27Kip1抗体进行免疫印迹实验。 更多
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
总数:1
Vitamin d induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. 2010 至该文献
为了说明在膀胱中维生素D可以诱导一种人类抗菌肽cathelicidin的表达，采用了Sigman Aldrich公司的抗CYP24A1（1：150）多克隆抗体进行免疫细胞化学实验。
锰超氧化物歧化酶 (manganese superoxide dismutase)
superoxide dismutase 2, mitochondrial
总数:8
CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells. 2008 至该文献
为了研究CD30信号在霍奇金细胞系和间变性大细胞淋巴瘤(ALCL)细胞系中的重要作用，采用了Upstate Biotechnology的抗MnSOD抗体进行免疫印迹试验。 更多
Shc
SHC (Src homology 2 domain containing) transforming protein 1
总数:19
Neurosteroid Dehydroepiandrosterone Interacts with Nerve Growth Factor (NGF) Receptors, Preventing Neuronal Apoptosis.. 2011 至该文献
为了研究去氢表雄酮和神经生长因子受体之间的相互作用，采用了Cell Signaling公司的抗Shc (2432,1:1000)和抗磷酸化Shc(2434,1:500)抗体进行了免疫印记实验。 更多
ETV4
ets variant 4
总数:3
Association of Ets-related transcriptional factor E1AF expression with overexpression of matrix metalloproteinases, COX-2 and iNOS in the early stage of colorectal carcinogenesis. 2005 至该文献
FBI 1
zinc finger and BTB domain containing 7A
总数:1
Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis. 2004 至该文献
PA2G4
proliferation-associated 2G4, 38kDa
总数:1
The ErbB3-binding protein Ebp1 suppresses androgen receptor-mediated gene transcription and tumorigenesis of prostate cancer cells. 2005 至该文献
MYO6
myosin VI
总数:3
Myosin II co-chaperone general cell UNC-45 overexpression is associated with ovarian cancer, rapid proliferation, and motility. 2007 至该文献
为了研究UNC-45在调节肿瘤细胞增殖和转移中的功能，使用了Sigma公司的小鼠抗myosin VI抗体来进行免疫印迹分析。 更多
p21
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
总数:173
The candidate tumor suppressor gene ECRG4 inhibits cancer cells migration and invasion in esophageal carcinoma. 至该文献
为了研究可能的抑癌基因ECRG4对食管癌细胞迁移和浸润的影响，采用了Santa Cruz公司的抗p21的抗体进行免疫印迹实验。 更多
FGF8
fibroblast growth factor 8 (androgen-induced)
BRM
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
总数:4
Repressive LTR Nucleosome Positioning by the BAF Complex Is Required for HIV Latency.. 2011 至该文献
为了研究SWI/SNF在潜伏期HIV LTR转录激活前后的调节作用，采用了Abcam BRM进行了蛋白质免疫印迹实验。 更多
p53
tumor protein p53
总数:239
The candidate tumor suppressor gene ECRG4 inhibits cancer cells migration and invasion in esophageal carcinoma. 至该文献
为了研究可能的抑癌基因ECRG4对食管癌细胞迁移和浸润的影响，采用了Santa Cruz公司的抗p53的抗体进行免疫印迹实验。 更多
GDF9
growth differentiation factor 9
总数:1
Expression and function of growth differentiation factor-9 in an oviparous species, Gallus domesticus. 2005 至该文献
WWP1
WW domain containing E3 ubiquitin protein ligase 1
总数:1
Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. 2006 至该文献
KLK14
kallikrein-related peptidase 14
总数:1
Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14. 2007 至该文献
GDF15
growth differentiation factor 15
总数:5
Activation of p53 by MEG3 non-coding RNA. 2007 至该文献
c-Myc
v-myc myelocytomatosis viral oncogene homolog (avian)
总数:143
Neurosteroid Dehydroepiandrosterone Interacts with Nerve Growth Factor (NGF) Receptors, Preventing Neuronal Apoptosis.. 2011 至该文献
为了研究去氢表雄酮和神经生长因子受体之间的相互作用，采用了Santa Cruz公司的抗c-myc (9E10, sc-40)抗体进行了免疫印记和免疫共沉淀实验。 更多
HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
总数:1
Early alterations in ovarian surface epithelial cells and induction of ovarian epithelial tumors triggered by loss of FSH receptor. 2007 至该文献
白细胞介素6 (IL-6)
interleukin 6 (interferon, beta 2)
总数:41
Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes.. 2011 至该文献
为了研究具有分解代谢功能的细胞器和具有合成代谢功能的细胞器二者在空间上的结合在促进分泌蛋白合成中的作用，采用R&D systems的抗IL6抗体进行免疫细胞化学试验。 更多
SLCO1B3
solute carrier organic anion transporter family, member 1B3
总数:1
The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3. 2007 至该文献
FGFR4
fibroblast growth factor receptor 4
总数:5
Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis. 2009 至该文献
为了研究是否成纤维细胞生长因子受体4在促进肝癌进程过程中具有一定的功能，使用了Santa Cruz Biotechnology公司的抗FGFR4抗体来进行免疫印迹分析。 更多
ITGA6
integrin, alpha 6
总数:20
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. 至该文献
为了研究乳癌细胞中由uPAR介导的细胞信号转导激发的特性，采用了Biolegend的抗CD49f-PE抗体进行流式细胞实验。 更多
Ezh2
enhancer of zeste homolog 2 (Drosophila)
总数:11
Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes.. 2010 至该文献
为了研究长间隔非编码RNA作为支架调节组蛋白修饰复合物和基因表达的功能，使用了Cell Signaling Technology公司的小鼠抗EZH2抗体来进行免疫印迹分析和RNA免疫沉淀实验。 更多
PAWR
PRKC, apoptosis, WT1, regulator
总数:2
Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane. 2004 至该文献
Ets1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
总数:13
Regulation of natriuretic peptide receptor-A gene expression and stimulation of its guanylate cyclase activity by transcription factor Ets-1. 2009 至该文献
为了研究转录因子Ets-1在调控Natriuretic Peptide Receptor-A基因表达中的作用，采用了Santa Cruz公司的Ets-1抗体产品，来进行免疫印迹实验。 更多
BTRC
beta-transducin repeat containing
总数:2
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. 2009 至该文献
为了研究FANCM在有丝分裂过程中的降解机制，使用了Zymed Laboratories的小鼠抗β-TRCP抗体来进行免疫印迹分析。 更多
VAV3
vav 3 guanine nucleotide exchange factor
总数:2
Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer. 2008 至该文献
HER2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
总数:69
Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer. 2008 至该文献
为了研究双调蛋白（amphiregulin）的表达与结直肠癌的肝转移之间的关系，采用了Zymed Laboratories公司的抗c-erbB-2的抗体进行免疫组化实验。 更多
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
总数:55
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2010 至该文献
为了研究mPGES-1在调控肿瘤生长、侵润和转移中的作用，采用了Santa Cruz Biotechnology公司的抗COX-2抗体产品，进行了免疫印迹实验。 更多
STAT5B
signal transducer and activator of transcription 5B
总数:23
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 2009 至该文献
为了鉴定ERBB4基因的突变在黑素瘤中所起的作用，使用了Upstate Biotech-Millipore公司的磷酸化抗体STAT5B来进行免疫印迹分析。 更多
p50
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
总数:80
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 至该文献
为了说明流感病毒感染期间IL-32表达水平的提高抑制病毒的复制，使用了Santa Cruz Biotechnology公司的anti-p50抗体来进行染色质免疫共沉淀实验。 更多
KLK5
kallikrein-related peptidase 5
总数:1
Premature terminal differentiation and a reduction in specific proteases associated with loss of ABCA12 in Harlequin ichthyosis. 2009 至该文献
为研究鱼鳞癣中与ABCA12丧失相关的形态学和生态学改变，使用了Santa Cruz公司的抗KLK5抗体来进行免疫组化分析。
CXCL16
chemokine (C-X-C motif) ligand 16
总数:2
EPHB4 regulates chemokine-evoked trophoblast responses: a mechanism for incorporating the human placenta into the maternal circulation. 2005 至该文献
CXCR5
chemokine (C-X-C motif) receptor 5
总数:4
Striking alteration of some populations of T/B cells in systemic lupus erythematosus: relationship to expression of CD62L or some chemokine receptors. 2008 至该文献
为了研究系统性红斑狼疮病人的一些T/B细胞的显著改变与CD62L或一些趋化因子受体表达的关系，采用了R&D的藻红蛋白(PE)结合的抗CXCR5(51505)抗体进行流式细胞术和免疫细胞化学试验。 更多
NAT1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
总数:1
Quantification of phase I/II metabolizing enzyme gene expression and polycyclic aromatic hydrocarbon-DNA adduct levels in human prostate. 2009 至该文献
RICTOR
RPTOR independent companion of MTOR, complex 2
总数:3
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs.. 2010 至该文献
为了研究4E-BPs对mTORC1信号通路的精确调控，使用了Cell Signaling Technology公司的抗rictor抗体来进行免疫印迹分析。 更多
HNRNPK
heterogeneous nuclear ribonucleoprotein K
总数:6
Proteomic and genomic analysis of PITX2 interacting and regulating networks. 2009 至该文献
为了研究PITX2相关联的蛋白与基因网络，使用了Epitomics公司的抗hnRNP K抗体来进行蛋白印迹分析。 更多
E2F1
E2F transcription factor 1
总数:36
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. 2010 至该文献
为了说明Skp2参与非p19Arf-p53途径的细胞衰老，使用了Santa Cruz公司的E2F1抗体来进行免疫印记实验。 更多
runt相关转录因子2 (RUNX2)
runt-related transcription factor 2
总数:16
Juvenile dermatomyositis calcifications selectively displayed markers of bone formation. 2009 至该文献
为了测定在幼年皮肌炎病理性钙化中SIBLING蛋白和骨组分的存在，使用了R&D Systems公司的抗Cbfa1抗体来进行免疫组化实验。 更多