类风湿性关节炎
基因
试剂
文献样例
产品评述样例
PADI4
peptidyl arginine deiminase, type IV
TRAF1
TNF receptor-associated factor 1
总数:3
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. 2010 至该文献
为了揭示HOIP在CD40信号通路中的泛素连接酶功能，使用了Santa Cruz Biotechnology公司的TRAF1抗体(N-19)来进行免疫印记实验。 更多
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
总数:6
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.. 2011 至该文献
为了研究人造血系统细胞给以不同刺激的反应能通过单细胞多因子分选进行分析，采用Biolegend的抗HLADR抗体以2ug/ml浓度进行细胞多因子分选实验。 更多
PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
STAT4
signal transducer and activator of transcription 4
总数:10
Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation. 2007 至该文献
为了研究Stat4依赖的Th1相关基因的遗传程序，采用了Santa Cruz Biotechnology公司的抗Stat4抗体进行ChIP分析 更多
C5
complement component 5
总数:1
The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q. 2005 至该文献
PRKCQ
protein kinase C, theta
总数:10
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 至该文献
为了证明CCL2通过Rho/PKCalpha信号通道相互作用引起脑内皮的通透性过高，使用了Cell Signaling Technology公司的抗磷酸-PKC-theta抗体，进行了免疫印迹实验。 更多
OLIG3
oligodendrocyte transcription factor 3
总数:1
Identification and subclassification of new Atoh1 derived cell populations during mouse spinal cord development. 2009 至该文献
使用T. Muller香猪抗OLIG3抗体培育胚胎切片来证明脊髓中存在依赖Atoh1的细胞类型。
CCL21
chemokine (C-C motif) ligand 21
总数:5
Internalizing antibodies to the C-type lectins, L-SIGN and DC-SIGN, inhibit viral glycoprotein binding and deliver antigen to human dendritic cells for the induction of T cell responses. 2006 至该文献
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
A20
tumor necrosis factor, alpha-induced protein 3
总数:3
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation.. 2011 至该文献
为了研究切割的NIK 导致非经典的NF- kB 活性 ，采用了Santa Cruz Biotechnology的抗A20抗体进行免疫印迹实验。 更多
KIF5A
kinesin family member 5A
总数:1
GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin. 2005 至该文献
白细胞介素17 (IL-17)
interleukin 17A
总数:16
The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence.. 2011 至该文献
为了研究血脑屏障的完整性和中枢神经免疫沉默能够被Shh信号通路促进，采用eBioscience的抗IL-17抗体进行流式细胞分选实验。 更多
IL 21
interleukin 21
总数:1
Evidence for multiple B- and T-cell epitopes in Plasmodium falciparum liver-stage antigen 3. 2009 至该文献
为了证明在人的肝脏部位抗原3(LSA-3)上存在着多个不同的T细胞和B细胞表位，并研究其在诱导产生抗疟原虫的保护机制中的作用，采用了Unipath公司的小鼠抗IgG4抗体(1:3000)，进行了ELISA实验。
TNF-alpha
tumor necrosis factor
总数:64
NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. 2008 至该文献
为了研究NFAT5在高渗压力下对人类角膜缘上皮细胞的作用，采用了R&D Systems的TNF-alpha抗体进行了蛋白质印迹实验。 更多
MMEL1
membrane metallo-endopeptidase-like 1
CD16
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
总数:41
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy.. 2011 至该文献
为了研究在天然杀伤细胞免疫突触处皮质肌动蛋白的重塑，采用了R&D systems的抗CD16抗体进行免疫细胞化学实验。 更多
CD40
CD40 molecule, TNF receptor superfamily member 5
总数:39
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. 2010 至该文献
为了揭示HOIP在CD40信号通路中的泛素连接酶功能，使用了Santa Cruz Biotechnology公司的CD40抗体(H-120)来进行免疫印记实验。 更多
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
总数:1
Differential expression of LIGHT and its receptors in human placental villi and amniochorion membranes. 2002 至该文献
TNFR2
tumor necrosis factor receptor superfamily, member 1B
总数:14
Control of chemokine gradients by the retinal pigment epithelium. 2008 至该文献
LAF4
AF4/FMR2 family, member 3
c-Rel
v-rel reticuloendotheliosis viral oncogene homolog (avian)
总数:15
Nuclear factor-kappaB activation is associated with somatic and germ line RET mutations in medullary thyroid carcinoma. 2008 至该文献
为了研究NF-κB的活化和RET突变之间的关联，采用了Santa Cruz Biotechnology的抗c-REL抗体进行免疫组化实验。 更多
FCRL3
Fc receptor-like 3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
总数:10
Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation.. 2011 至该文献
为了研究切割的NIK 导致非经典的NF- kB 活性 ，采用了Cell Signaling Technology的抗p100/52 抗体进行免疫印迹实验。 更多
光 (LIGHT)
tumor necrosis factor (ligand) superfamily, member 14
总数:2
Differential expression of LIGHT and its receptors in human placental villi and amniochorion membranes. 2002 至该文献
IL 23
interleukin 23, alpha subunit p19
IRF5
interferon regulatory factor 5
总数:1
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. 至该文献
为了说明IRF5同HATs和HDACs一起调控促炎细胞因子的转录水平表达，使用了Abcam公司的山羊抗IRF5多克隆抗体进行免疫共沉淀实验。
CTLA 4
cytotoxic T-lymphocyte-associated protein 4
总数:5
Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell Extrinsic Function of CTLA-4.. 2011 至该文献
为了揭示CTLA-4为何能够抑制CD28的激活，采用Santa Cruz的抗CTLA-4抗体进行免疫细胞化学试验。 更多
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4
cdk6
cyclin-dependent kinase 6
总数:20
Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA.. 2010 至该文献
为了研究疱疹病毒非编码RNA HSURs在调节宿主细胞microRNA中的功能，使用了Abcam公司的抗Cdk6抗体来进行免疫印迹分析。 更多
白细胞介素2 (interleukin 2)
总数:15
Identification of IL-17-producing FOXP3+ regulatory T cells in humans. 2009 至该文献
为了确定IL-17+，FOXP3+调节性T细胞产生于外周血中，使用了R&D Systems公司的白介素2酶联免疫吸附试剂盒进行酶联免疫吸附实验。 更多
CIITA
class II, major histocompatibility complex, transactivator
总数:5
A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages. 2009 至该文献
为了研究JAK-STAT1通道在调控HSV-1复制中的作用，使用了Biolegend公司的抗MHC class II-APC 抗体，来收集和染色受感染的细胞，进行了流式细胞计量实验。 更多
RANKL
tumor necrosis factor (ligand) superfamily, member 11
总数:7
Differential expression of RANK, RANK-L, and osteoprotegerin by synovial fluid neutrophils from patients with rheumatoid arthritis and by healthy human blood neutrophils. 2007 至该文献
为了研究患类风湿性关节炎病人的RANK、RANK-L、和骨保护素不同表达，使用了R&D Systems公司的单克隆抗人体OPG抗体，进行了酶联免疫吸附测定实验。 更多
白细胞介素1beta (IL-1beta)
interleukin 1, beta
总数:28
Local and systemic responses in matrix metalloproteinase 8-deficient mice during Porphyromonas gingivalis-induced periodontitis. 2009 至该文献
为了研究牙龈卟啉单胞菌所致牙周炎中基质金属蛋白酶8的作用，在免疫染色试验中将R&D Systems的interleukin-1β作用于石蜡包被的组织样品上。 更多
白细胞介素6受体 (IL-6R)
interleukin 6 receptor
总数:10
The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells. 2009 至该文献
使用BD抗IL-6Rα 抗体在流式细胞法中，来证明IL-6 通过增加IL-21产物来促进抗体生成。 更多
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
CD226
CD226 molecule
白细胞介素6 (IL-6)
interleukin 6 (interferon, beta 2)
总数:41
Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes.. 2011 至该文献
为了研究具有分解代谢功能的细胞器和具有合成代谢功能的细胞器二者在空间上的结合在促进分泌蛋白合成中的作用，采用R&D systems的抗IL6抗体进行免疫细胞化学试验。 更多
osteoprotegerin
tumor necrosis factor receptor superfamily, member 11b
总数:2
Calcification of human vascular smooth muscle cells: associations with osteoprotegerin expression and acceleration by high-dose insulin. 2007 至该文献
在夹心酶联免疫分析实验中使用了R&D Systems公司的小鼠抗人OPG和生物素标记的山羊抗人OPG用于检测人血管平滑肌细胞条件培养基中OPG的浓度。 更多
FCGR2B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
总数:6
Loss of CD103(+) intestinal dendritic cells during colonic inflammation. 2010 至该文献
为了了研究小鼠诱发大肠炎前后肠内树突状细胞可能的差异，采用了BD Pharmingen 公司的CD32抗体产品，进行了流式细胞分析实验。 更多
ICOS
inducible T-cell co-stimulator
总数:3
Lack of disease specificity limits the usefulness of in vitro costimulation in HIV- and HCV-infected patients. 2008 至该文献
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
总数:1
Regulation of human methylenetetrahydrofolate reductase by phosphorylation. 2005 至该文献
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
总数:2
Expression of TNF-superfamily members BAFF and APRIL in breast cancer: immunohistochemical study in 52 invasive ductal breast carcinomas. 2008 至该文献
CCR5
chemokine (C-C motif) receptor 5
总数:28
Effects of ferumoxides-protamine sulfate labeling on immunomodulatory characteristics of macrophage-like THP-1 cells. 2008 至该文献
Biolegend 荧光素共轭的鼠抗人 CD195 免疫球蛋白G2a用于流式细胞术来演示吞噬的FePro纳米粒不能显著的影响THP-1细胞的免疫特性。 更多
HLA-DR
major histocompatibility complex, class II, DR alpha
总数:21
Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. 2008 至该文献
为了研究IRAK-1信号阻断对TLR2和TLR4诱导的人树突状细胞耐受有重要作用，采用Beckman-Coulter的抗HLA DR- PC5抗体进行流式细胞分选实验。 更多
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
总数:3
Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. 2008 至该文献
IL33
interleukin 33
总数:1
IL-33 exacerbates antigen-induced arthritis by activating mast cells. 2008 至该文献
MMP-3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
总数:8
Matrix metalloproteinase activity in pediatric acute lung injury. 2009 至该文献
为了研究基质中金属蛋白酶在儿童急性肺损伤中的作用，使用了R/D Systems公司的MMP-3抗体来进行免疫印迹实验。 更多
Ⅱ型胶原 (type II collagen)
collagen, type II, alpha 1
总数:14
Fibroblast growth factor 18 gives growth and directional cues to airway cartilage. 2009 至该文献
为了研究FGF18在Sox9的表达中的调控作用，使用了Lab Vision Products公司的鼠单克隆抗Col2A1抗体，进行了免疫组织化学实验。 更多
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
总数:2
Epstein-Barr virus transcription activator Rta upregulates decoy receptor 3 expression by binding to its promoter. 2007 至该文献
为研究P3HR1 细胞和 EBV转染的293细胞中诱骗受体3（DcR3）的表达上调是否出现在EBV复活之前，采用BioLegend 公司生产的DcR3抗体用于免疫印迹实验。 更多
RFC1
replication factor C (activator 1) 1, 145kDa
CD32
Fc fragment of IgG, low affinity IIa, receptor (CD32)
总数:7
Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcgammaRIIa and the integrin beta3 cytoplasmic domain. 2009 至该文献
为探讨依替巴肽引起的血小板减少症和血栓形成的病因学，将BD Biosciences — Pharmingen提供的FITC标记的单克隆抗FcγRIIa抗体用于蛋白免疫印迹实验中。 更多
血清淀粉样蛋白A蛋白 (SAA1)
serum amyloid A1
总数:2
Human apoC-IV: isolation, characterization, and immunochemical quantification in plasma and plasma lipoproteins. 2003 至该文献
IL 15
interleukin 15
总数:6
Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo. 2009 至该文献
为了研究IL-15Rα同特异性免疫反应的关系， 采用了R&D Systems公司的抗人白介素15受体α抗体，进行了酶联免疫实验。 更多
白细胞介素10 (IL-10)
interleukin 10
总数:20
Identification of IL-17-producing FOXP3+ regulatory T cells in humans. 2009 至该文献
为了确定IL-17+，FOXP3+调节性T细胞产生于外周血中，使用了R&D Systems公司的白介素10酶联免疫吸附试剂盒进行酶联免疫吸附实验。 更多
P2X7
purinergic receptor P2X, ligand-gated ion channel, 7
总数:1
Modulation of P2X7 receptor functions by polymyxin B: crucial role of the hydrophobic tail of the antibiotic molecule. 2007 至该文献
为研究多粘菌素B（polymyxin B）对嘌呤受体P2X7受体功能的调控机制，采用Sigma 公司生产的 P2X7受体抗体用于免疫印迹实验。
MCP-1
chemokine (C-C motif) ligand 2
总数:14
Monocyte chemoattractant protein 1 and CD40 ligation have a synergistic effect on vascular endothelial growth factor production through cyclooxygenase 2 upregulation in gastric cancer. 2008 至该文献
为了研究单核细胞趋化蛋白1和CD40配基化对血管内皮生长因子产量的影响，采用了Santa Cruz公司的抗MCP-1抗体进行了免疫组织化学实验。 更多
JNK
mitogen-activated protein kinase 8
总数:190
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. 2010 至该文献
为研究如何通过两阶段MAPK反应区分上皮细胞盾壳菌的酵母和菌丝形态，采用了Cell Signaling Technologies公司的抗磷酸化JNK抗体进行蛋白质印迹试验。 更多
MBL2
mannose-binding lectin (protein C) 2, soluble
总数:4
Protein kinase CK2 phosphorylation regulates the interaction of Kaposi's sarcoma-associated herpesvirus regulatory protein ORF57 with its multifunctional partner hnRNP K. 2004 至该文献
AGER
advanced glycosylation end product-specific receptor
OPN
secreted phosphoprotein 1
总数:12
Increased levels of active c-Src distinguish invasive from in situ lobular lesions. 2009 至该文献
为了研究c-Src激酶是否会促使非典型小叶增生或小叶原位癌转变为浸润性小叶癌，使用了Calbiochem公司的抗osteopontin抗体(1:100)进行免疫荧光实验。 更多
TYMS
thymidylate synthetase
总数:4
The roles of thymidylate synthase and p53 in regulating Fas-mediated apoptosis in response to antimetabolites. 2004 至该文献
IL1RN
interleukin 1 receptor antagonist
总数:1
Beta-(1-->3)-D-glucan modulates DNA binding of nuclear factors kappaB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1beta/IL-1 receptor antagonist ratio. 2006 至该文献
MMP13
matrix metallopeptidase 13 (collagenase 3)
总数:7
Expression and prognostic role of MMP2, MMP9, MMP13, and MMP14 matrix metalloproteinases in sinonasal and oral malignant melanomas. 2008 至该文献
为了研究鼻窦和口腔恶性黑色素瘤病人中基质金属蛋白酶的表达以及其预兆作用，采用了Oncogene的鼠单克隆抗MMP13抗体进行免疫组织化学试验。 更多
DKK1
dickkopf 1 homolog (Xenopus laevis)
总数:5
Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer. 2008 至该文献
为了考察Dickkopfs (Dkks)和Kremen2 (Krm2)在胃肠道癌症中表达的变化，使用了Abcam公司的抗DKK-1的山羊抗人抗体进行了免疫组化实验。 更多
VCAM-1
vascular cell adhesion molecule 1
总数:19
The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways. 2009 至该文献
为研究前列腺特异膜抗原在前列腺癌细胞的白介素6和CCL5的表达调控中所发挥的角色，将Immunotech提供的抗血管细胞粘附分子抗体用于阻断或激活实验中。 更多
AML1
runt-related transcription factor 1
总数:3
RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis. 2008 至该文献
Sigma公司生产的抗RUNX1多克隆抗体（兔）可用于免疫细胞化学实验，来研究E4orf6、E1B-55K及 RUNX1间的相互作用，以及RUNX1与病毒DNA?RNA核心的联系。 更多
interleukin 23 receptor
总数:2
Cutting edge: A critical functional role for IL-23 in psoriasis. 至该文献
为了研究IL－23在银屑病中扮演的角色并寻找慢性上皮炎症性疾病的新的治疗策略，采用了R&D Systems的抗IL-23R抗体进行流式细胞和免疫组化实验。 更多
NLRP3
NLR family, pyrin domain containing 3
总数:1
Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. 2006 至该文献
Toll样受体4 (TLR4)
toll-like receptor 4
总数:36
Expression of Toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: upregulated expression of TLR2 in terminal ileum of patients with ulcerative colitis. 2008 至该文献
为了研究回肠粘膜中TLR2、TLR4和及其转膜辅助受体CD14的表达情况，采用Santa Cruz Biotechnology公司的羊抗TLR4多克隆抗体（1：10）进行免疫组织化学实验。 更多
MMP-1
matrix metallopeptidase 1 (interstitial collagenase)
总数:12
Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 至该文献
为研究CD147促使成肌纤维细胞分化在组织变构中的作用，采用了Calbiochem公司的抗MMP-1单克隆抗体进行蛋白质印迹试验。 更多
Toll样受体2 (TLR2)
toll-like receptor 2
总数:22
Inflammatory role of Toll-like receptors in human and murine adipose tissue. 2010 至该文献
为了研究人和鼠科脂肪组织中Toll样受体与网膜脂肪组织相关的炎症之间的关系，采用了Hycult Biotechnologies的单抗TLR2抗体进行ELISA实验。 更多
p50
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
总数:80
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. 至该文献
为了说明流感病毒感染期间IL-32表达水平的提高抑制病毒的复制，使用了Santa Cruz Biotechnology公司的anti-p50抗体来进行染色质免疫共沉淀实验。 更多
CD25
interleukin 2 receptor, alpha
总数:44
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. 2009 至该文献
为了研究树突细胞在调控自发性致死性自身免疫性疾病中的作用，采用了eBioscience公司的抗CD25抗体产品，进行了流失细胞分析实验。 更多
Mediterranean fever
脂联素 (adiponectin)
adiponectin, C1Q and collagen domain containing
总数:6
The mixed-lineage kinase DLK is a key regulator of 3T3-L1 adipocyte differentiation. 2009 至该文献
为了研究DLK在调控3T3-L1脂肪细胞分化中的作用，使用了Calbiochem公司的兔多克隆抗adiponectin抗体，进行了免疫印迹和沉淀实验。 更多
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase
肿瘤坏死因子受体超家族成员6 (Fas)
Fas (TNF receptor superfamily, member 6)
总数:52
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 至该文献
为了说明YB-1、GST、ABCB5和ERK3能够成为乳腺癌细胞耐药性治疗的潜在靶点，使用了Santa Cruz Biotechnology公司的FAS抗体(1:500)来进行免疫印记实验。 更多
白细胞介素18 (IL-18)
interleukin 18 (interferon-gamma-inducing factor)
总数:6
Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity.. 2005 至该文献
高迁移率族蛋白B1 (HMGB1)
high mobility group box 1
总数:9
Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. 2009 至该文献
为了研究在肾脏移植过程中供体Toll样受体4通过诱导局部出血和再灌注对肾脏损伤的影响，使用了Abnova公司的抗HMGB1抗体来进行免疫荧光试验。 更多
HLA DQA1
major histocompatibility complex, class II, DQ alpha 1
总数:4
Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid beta-protein. 2002 至该文献
PON1
paraoxonase 1
总数:2
Oligomeric states of the detergent-solubilized human serum paraoxonase (PON1). 2002 至该文献
白细胞介素8 (IL-8)
interleukin 8
总数:46
Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes.. 2011 至该文献
为了研究具有分解代谢功能的细胞器和具有合成代谢功能的细胞器二者在空间上的结合在促进分泌蛋白合成中的作用，采用R&D systems的抗IL8抗体进行免疫细胞化学试验。 更多
resistin
总数:2
Dominant inhibitory adipocyte-specific secretory factor (ADSF)/resistin enhances adipogenesis and improves insulin sensitivity. 2004 至该文献
iNOS
nitric oxide synthase 2, inducible
总数:38
MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells. 2008 至该文献
为了研究MEKK-1在细胞因子诱导的信号通路中的作用，采用Santa Cruz Biotechnologies抗NOS-2抗体进行免疫印迹实验。 更多
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
总数:1
Expression of CD80 and CD86 costimulatory molecules are potential markers for better survival in nasopharyngeal carcinoma. 2007 至该文献
为了研究CD80和CD86可能作为鼻咽癌预后的标记物，采用Novocastra Laboratories的抗HLA Class II (DR)抗体进行免疫组织化学实验。
ICAM-1
intercellular adhesion molecule 1
总数:28
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy.. 2011 至该文献
为了研究在天然杀伤细胞免疫突触处皮质肌动蛋白的重塑，采用了R&D systems的抗ICAM-1抗体进行免疫细胞化学实验。 更多
CRP
C-reactive protein, pentraxin-related
总数:13
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. 2009 至该文献
为研究有活性的gp130在炎症性肝细胞肿瘤中所发挥的作用，将Abcam提供的单克隆抗C反应蛋白抗体应用于免疫组织化学实验中。 更多
IL1A
interleukin 1, alpha
总数:5
Intracellular IL-1alpha-binding proteins contribute to biological functions of endogenous IL-1alpha in systemic sclerosis fibroblasts. 2006 至该文献
白细胞介素4 (IL-4)
interleukin 4
总数:18
The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence.. 2011 至该文献
为了研究血脑屏障的完整性和中枢神经免疫沉默能够被Shh信号通路促进，采用R&D Systems的抗IL-4抗体以5ug/ml浓度进行细胞刺激实验。 更多
ATP结合转运蛋白B超家族成员1 (ABCB1)
ATP-binding cassette, sub-family B (MDR/TAP), member 1
总数:15
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance. 2010 至该文献
为了说明YB-1、GST、ABCB5和ERK3能够成为乳腺癌细胞耐药性治疗的潜在靶点，使用了Santa Cruz Biotechnology公司的MDR1抗体(1:500)来进行免疫印记实验。 更多
NOD2
nucleotide-binding oligomerization domain containing 2
总数:2
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. 2006 至该文献
Akt
v-akt murine thymoma viral oncogene homolog 1
总数:418
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H?-ATPase.. 2011 至该文献
为了研究泡状H+-ATPase参与到mTOR通路中mTORC1的转位和激活，采用Cell Signaling的抗Akt和抗S473磷酸化Akt抗体进行蛋白印迹实验。 更多
TGF-beta1
transforming growth factor, beta 1
总数:33
Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. 2008 至该文献
为研究CD147促使成肌纤维细胞分化在组织变构中的作用，采用了R&D Systems公司的抗pan-TGFβ抗体进行抑制试验。 更多
PAI-1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
总数:15
Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. 2010 至该文献
为了研究人纤溶酶原和钩端螺旋体内皮抑制素样蛋白A之间的相互作用，采用Novus Biologicals公司的山羊抗人纤溶酶原抗体进行酶联免疫吸附实验。 更多
肥胖荷尔蒙 (leptin)
总数:6
De-Novo Identification of PPARgamma/RXR Binding Sites and Direct Targets during Adipogenesis. 2009 至该文献
为了通过基因组范围筛查的方式发现在脂肪生成过程中的PPAR Gamma和RXR的结合位点，使用了Santa Cruz Biotechnology公司的抗Ob抗体来进行免疫印迹分析。 更多
血管内皮生长因子 (VEGF)
vascular endothelial growth factor A
总数:76
Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib. 2008 至该文献
为了研究不间断给药伊立替康（irinotecan）对结肠直肠癌细胞的影响，采用了Oncogene Research Products公司的VEGF-A抗体进行免疫组化实验。 更多
p53
tumor protein p53
总数:239
The candidate tumor suppressor gene ECRG4 inhibits cancer cells migration and invasion in esophageal carcinoma. 至该文献
为了研究可能的抑癌基因ECRG4对食管癌细胞迁移和浸润的影响，采用了Santa Cruz公司的抗p53的抗体进行免疫印迹实验。 更多
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
总数:55
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. 2010 至该文献
为了研究mPGES-1在调控肿瘤生长、侵润和转移中的作用，采用了Santa Cruz Biotechnology公司的抗COX-2抗体产品，进行了免疫印迹实验。 更多