血管内皮细胞
基因
试剂
文献样例
产品评述样例
eNOS
nitric oxide synthase 3
总数:36
Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells. 2009 至该文献
为了研究purinergic在调控内皮细胞一氧化氮合成酶活性中的作用,采用了Upstate Laboratories公司的抗eNOS抗体产品,进行了免疫印迹实验。 更多
血管假性血友病因子 (von Willebrand factor)
总数:32
Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells. 2009 至该文献
为研究Rab27a和MyRIP对内皮细胞释放的血管假性血友病因子的调节作用,使用了Serotec公司的羊源性VWF抗体检测假性血友病因子。 更多
VE钙粘蛋白 (VE cadherin)
cadherin 5
总数:19
Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis. 2009 至该文献
为了阐明在人类多发性骨髓瘤中的血管发生可能由肿瘤产生多效蛋白发展而来,它能够诱导单核细胞转分化为血管内皮细胞,采用了eBioscience公司的抗CD144抗体,进行了免疫组织化学实验。 更多
血管内皮生长因子 (VEGF)
vascular endothelial growth factor A
总数:81
DLC1 negatively regulates angiogenesis in a paracrine fashion. 2010 至该文献
为了研究DLC1对肿瘤发生过程中血管再生的影响,采用了Santa Cruz biotechnology抗VEGF抗体来进行免疫组织化学实验。 更多
tie-2
TEK receptor tyrosine kinase
总数:11
Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis. 2009 至该文献
为了阐明在人类多发性骨髓瘤中的血管发生可能由肿瘤产生多效蛋白发展而来,它能够诱导单核细胞转分化为血管内皮细胞,采用了Santa Cruz Biotechnology公司的抗Flk-1抗体,进行了蛋白质印迹实验。 更多
VEGFR-2 (VEGFR-2)
kinase insert domain receptor
总数:35
Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling.. 2010 至该文献
为了研究Wnt信号途径中凝乳酶原受体和H+-ATPase介导的酸化所起的重要作用,使用了Santa Cruz公司的抗Flk-1抗体来进行免疫沉淀。 更多
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif 13
总数:1
Persistent redistribution of poly-adenylated mRNAs correlates with translation arrest and cell death following global brain ischemia and reperfusion. 2008 至该文献
为了研究稳定转染的机制,采用Santa Cruz生物技术公司的TTP抗体进行免疫细胞化学实验。
ICAM-1 (ICAM-1)
intercellular adhesion molecule 1
总数:30
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy. 2011 至该文献
为了研究在天然杀伤细胞免疫突触处皮质肌动蛋白的重塑,采用了R&D systems的抗ICAM-1抗体进行免疫细胞化学实验。 更多
tissue factor
coagulation factor III, tissue factor
总数:5
Versican G3 domain promotes blood coagulation through suppressing the activity of tissue factor pathway inhibitor-1. 2006 至该文献
血栓调节蛋白 (thrombomodulin)
总数:8
IL-32-dependent effects of IL-1beta on endothelial cell functions. 2009 至该文献
为研究IL-32在IL-1β对内皮细胞功能的影响过程中所发挥的作用,将R&Dsystems提供的不规则siRNA(沉默子阴性对照1)用于蛋白免疫印迹实验中。 更多
内皮细胞选择素 (E-selectin)
selectin E
总数:5
The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor alpha expression in the synovium. 2008 至该文献
使用R & D 单克隆抗E选择蛋白抗体(BBIG-E4)进行免疫组织化学实验来研究是否类风湿关节炎肿瘤坏死因子(TNF)α封闭疗法产生的异质临床反应,可以用治疗开始之前滑膜(TNF)α的表达水平预测。 更多
PROCR
protein C receptor
总数:4
Endothelial protein C receptor is overexpressed in rheumatoid arthritic (RA) synovium and mediates the anti-inflammatory effects of activated protein C in RA monocytes. 2007 至该文献
为了确定与EPCR连接的主要细胞型,以及是否EPCR能调节激活蛋白C (APC)对这些细胞的影响,采用了R&D systems公司的羊抗人EPCR抗体进行免疫化学分析 更多
VCAM-1 (VCAM-1)
vascular cell adhesion molecule 1
总数:19
The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways. 2009 至该文献
为研究前列腺特异膜抗原在前列腺癌细胞的白介素6和CCL5的表达调控中所发挥的角色,将Immunotech提供的抗血管细胞粘附分子抗体用于阻断或激活实验中。 更多
内皮素1 (endothelin 1)
总数:9
Expression of endothelial nitric oxide synthase and endothelin-1 in skin tissue from amputated limbs of patients with complex regional pain syndrome. 2008 至该文献
为了检测eNOS和ET-1的分布与在切断四肢的CRPS病人的皮肤组织中通过由内皮标记CD31免疫反应代表的血管浓度有关,采用R&D systems鼠的抗人ET-1抗体(3G10),进行免疫组织化学实验。 更多
JNK
mitogen-activated protein kinase 8
总数:193
The germinal center kinase TNIK is required for canonical NF-?B and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. 2012 至该文献
为了研究在B细胞中TNIK在经典的NF-kB和JNK通路中扮演何种角色及如何发挥这种作用,采用了Santa Cruz Biotechnology的JNK1抗体进行免疫印迹实验。 更多
AGER
advanced glycosylation end-product specific receptor
CD18
integrin subunit beta 2
总数:23
CBFbeta is critical for AML1-ETO and TEL-AML1 activity. 2009 至该文献
CYBB
cytochrome b-245 beta chain
总数:7
IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase. 2009 至该文献
为了研究IL-6对前脑GABAergic中间神经元退化中的作用以及对老年老鼠的认知损伤的影响,使用了BD Transduction公司的抗Nox2单克隆抗体来进行免疫细胞化学实验。 更多
CXCL12
C-X-C motif chemokine ligand 12
总数:8
PTCH1 +/- dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts. 2009 至该文献
为了研究痣样基底细胞癌综合征成纤维细胞中PTCH1+/−基因表型与基底细胞癌发生的相关性,采用了Abcam公司生产的兔抗人SDF1-alpha(又叫CXCL12)多克隆抗体用于免疫印迹实验。 更多
BMPR2
bone morphogenetic protein receptor type 2
总数:7
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. 2009 至该文献
为了研究Smurf2在促进乳腺癌转移中的功能,使用了R&D systems公司的抗BMPRII抗体来进行免疫印迹分析。 更多
perlecan
heparan sulfate proteoglycan 2
总数:5
WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. 2006 至该文献
整合素αⅤ (integrin alpha v)
integrin subunit alpha V
总数:24
TGFBI expression is associated with a better response to chemotherapy in NSCLC. 2010 至该文献
为了确定整合素αvβ3是否影响TGFBI介导的NSCLC细胞对化学疗法的敏感性,采用Chemicon Interational的抗整合素αvβ3单抗进行流式细胞术实验。 更多
CYP2C9
cytochrome P450 family 2 subfamily C member 9
总数:4
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity. 2008 至该文献
CRP
C-reactive protein
总数:13
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. 2009 至该文献
为研究有活性的gp130在炎症性肝细胞肿瘤中所发挥的作用,将Abcam提供的单克隆抗C反应蛋白抗体应用于免疫组织化学实验中。 更多
LFA-1 (LFA-1)
integrin subunit alpha L
总数:14
Altered gene expression in early atherosclerosis is blocked by low level apolipoprotein E. 2008 至该文献
VASH1
vasohibin 1
总数:1
Alternative splicing of vasohibin-1 generates an inhibitor of endothelial cell proliferation, migration, and capillary tube formation. 2008 至该文献
R&D systems的血管抑制蛋白抗体被用于蛋白质印迹实验,来对内皮集落形成细胞中血管抑制蛋白1的可变剪接产物与血管抑制蛋白1的主要异形体(VASH1A),就抗血管生成的作用进行比较。
EPH受体B4 (EphB4)
EPH receptor B4
总数:7
The association between elevated EphB4 expression, smoking status, and advanced-stage disease in patients with head and neck squamous cell carcinoma. 2006 至该文献
为了研究EphB4的高表达,吸烟状态和晚期头颈部鳞状细胞癌之间的关系,采用了Santa Cruz Biotech的EphB4抗体进行免疫印迹和免疫组化试验。 更多
TJP2
tight junction protein 2
总数:3
EspF Interacts with nucleation-promoting factors to recruit junctional proteins into pedestals for pedestal maturation and disruption of paracellular permeability. 2008 至该文献
整合素β3 (integrin beta3)
integrin subunit beta 3
总数:28
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression. 2010 至该文献
为了研究活化状态的p42/44和p38在MMP-13表达中的作用,采用了Santa Cruz Biotechnology公司的小鼠单克隆整合素β3抗体(1:1000),进行了蛋白质印迹实验。 更多
Ras相关C3肉毒杆菌毒素底物1 (Rac1)
Rac family small GTPase 1
总数:55
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. 2009 至该文献
为研究RhoGDI2通过Rho GTPases抑制代谢的作用,采用了Millipore公司的抗Rac1单克隆抗体(1:1,000)进行免疫印迹试验。 更多
ACVRL1
activin A receptor like type 1
总数:4
TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. 2008 至该文献
为了研究在人和鼠肺部发育晚期时TGF-beta信号的动态调节,采用了R&D Systems的羊抗Acvrl1(AF370)抗体进行免疫组织化学和免疫印迹试验。 更多
NOX4
NADPH oxidase 4
总数:2
Mutational analysis reveals distinct features of the Nox4-p22 phox complex. 2008 至该文献
为了研究p22phox关键性的调控亚基和Nox4之间的相互作用关系,采用了Santa Cruz Biotechnology公司的兔抗Nox4(7843)多克隆抗体进行免疫印迹和免疫细胞化学实验。 更多
血管紧张素转化酶 (ACE)
angiotensin I converting enzyme
总数:8
Identification of beta-secretase (BACE1) substrates using quantitative proteomics. 2009 至该文献
为了研究通过定量蛋白质组学发现新的BACE1底物,采用Santa Cruz的ACE抗体以1:1,000稀释进行蛋白印迹实验。 更多
MIR126
microRNA 126
PAI-1 (PAI-1)
serpin family E member 1
总数:16
Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. 2010 至该文献
为了研究人纤溶酶原和钩端螺旋体内皮抑制素样蛋白A之间的相互作用,采用Novus Biologicals公司的山羊抗人纤溶酶原抗体进行酶联免疫吸附实验。 更多
p38
mitogen-activated protein kinase 14
总数:189
NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. 2008 至该文献
为了研究NFAT5在高渗压力下对人类角膜缘上皮细胞的作用,采用了Biosource International的p38抗体进行了蛋白质印迹实验。 更多
apelin
总数:1
Apelin mediates the induction of profibrogenic genes in human hepatic stellate cells. 2010 至该文献
为了研究apelin参与人类肝脏疾病纤维化形成中的作用,采用了Santa Cruz Biotechnology的兔抗AP抗体进行了免疫荧光实验。
Vegfr-3
fms related tyrosine kinase 4
总数:15
Expression of VEGF-C and its receptor VEGFR-3 in the bone marrow of patients with acute myeloid leukaemia. 2008 至该文献
为了研究急性髓性白血病人骨髓中VEGF-C和VEGFR-3的表达,采用了Santa Cruz的抗VEGFR-3(sc-321)抗体进行免疫组织化学试验。 更多
CXCR2
C-X-C motif chemokine receptor 2
总数:9
The role of the chemokines MCP-1, GRO-alpha, IL-8 and their receptors in the adhesion of monocytic cells to human atherosclerotic plaques. 2008 至该文献
为了研究在人动脉粥样硬化斑块中的趋化因子MCP-1, GRO-α, IL-8和它们的受体在与单核细胞粘附中的作用,采用R&D Systems公司的CXCR2 IgG2a抗体,进行抑制细胞粘附实验。 更多
趋化因子受体4 (CXCR4)
C-X-C motif chemokine receptor 4
总数:39
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 至该文献
为了研究人造血系统细胞给以不同刺激的反应能通过单细胞多因子分选进行分析,采用Biolegend的抗CXCR4抗体以3ug/ml浓度进行细胞多因子分选实验。 更多
血小板型选择素 (P-selectin)
selectin P
总数:8
Effect of tumour necrosis factor-alpha receptor 1 genetic deletion on carrageenan-induced acute inflammation: a comparison with etanercept. 2008 至该文献
为了评估体内肿瘤坏死因子-αR1在炎症疾病发病机理的作用,采用了Santa Cruz生物技术公司的抗P-选择素抗体(1:500)进行了免疫组化实验。 更多
CLDN5
claudin 5
总数:3
Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. 2006 至该文献
DLL4
delta like canonical Notch ligand 4
总数:1
Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. 2007 至该文献
I. B. Lobov(Regeneron Pharmaceuticals)的Dll4抗体被用于免疫组织化学实验中,来研究Dll4蛋白在血管生长和分化中的作用。
PGF
placental growth factor
总数:3
A reproducible and quantifiable model of choroidal neovascularization induced by VEGF A165 after subretinal adenoviral gene transfer in the rabbit. 2008 至该文献
Flt-1
fms related tyrosine kinase 1
总数:16
The association of vascular endothelial growth factor receptor-1 with the risk of cancer progression following radical prostatectomy. 2008 至该文献
为证明VEGFRR-1的表达与根治性前列腺切除术后病人肿瘤的演进风险不具有相关性,采用R&D Systems的羊抗人VEGFR-1多克隆抗体(catalog number: AF321)进行免疫组织化学实验。 更多
FGF-2 (FGF-2)
fibroblast growth factor 2
总数:20
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents. 2009 至该文献
为研究内皮衍生的成纤维生长因子2在人和啮齿类动物的肺动脉高压的进程中所发挥的作用,将Chemicon提供的兔多克隆抗纤维生长因子2抗体用于蛋白免疫印迹实验中。 更多