产品简要
公司名称 :
ACROBiosystems
产品类型 :
蛋白
产品名称 :
人类脂联素/ADIPOQ蛋白, Fc标签
目录 :
ADQ-H5250
规格 :
100微克, 1毫克
价格 :
260美元, 1500美元
更多信息或购买 :
产品信息
公司名称 :
ACROBiosystems
产品类型 :
蛋白
目录 :
ADQ-H5250
产品名称 :
人类脂联素/ADIPOQ蛋白, Fc标签
规格 :
100微克, 1毫克
价格 :
260美元, 1500美元
规格&价格 :
$260/100ug,$1500/1mg (500ug × 2)
靶标 :
脂联素
宿主物种 :
人类
By Tag :
Fc标签
研究 :
For Research Use Only
来源 :
Human ADIPOQ, Fc Tag (ADQ-H5250) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - Asn 244 (Accession # NP_001171271).
内毒素 :
Less than 1.0 EU per μg by the LAL method.
纯度 :
>92% as determined by SDS-PAGE.
SDS-PAGE Remark(R&NR) :
Human ADIPOQ, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%.
配方 :
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
重组 :
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
储存 :
For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: ● -20°C to -70°C for 12 months in lyophilized state; ● -70℃ for 3 months under sterile conditions after reconstitution.
背景 :
Adiponectin is also referred to as GBP-28, APM1, ADIPOQ, ACDC and Acrp30, is a secreted protein which contains one C1q domain (commonly called the globular domain) and onecollagen-like domain. Adiponectin / ADIPOQ is synthesized exclusively by adipocytes and secreted into plasma. ADIPOQ is important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Acrp30 Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway and may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
参考文献 :
(1) Nakano Y., et al., 1996, J. Biochem. 120:803-812. (2) Yamauchi T., et al., 2001, Nat. Med. 7:941-946. (3) Richards A.A., et al., 2006, Mol. Endocrinol. 20:1673-1687.
更多信息或购买 :
公司信息
ACROBiosystems
1 Innovation Way Newark, DE 19711, USA
order@acrobiosystems.com
http://www.acrobiosystems.com
1-800-810-0816
ACROBiosystems is a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics, vaccines and diagnostic kits.

Our team has worked tirelessly since the genomic sequence of SARS-CoV-2 was first published, developing a serial of critical reagents to fight COVID-19. Our team has successfully developed a new neutralizing antibody titer serologic assay kit for COVID-19 vaccine evaluation (Cat.No.TAS-K022) which really showed excellent performance.

As the emerging variants may have impacted on the development of the COVID-19 epidemic, our team is also going full steam ahead on developing a collection of spike mutants for the emerging variants of SARS-COV-2. The reagents can be used to evaluate the efficacy of the antibodies and vaccination.

We have also developed an extensive collection of recombinant proteins to support the development for bispecific antibodies, antibody drug conjugates and cell therapies.