产品简要
公司名称 :
ALPCO
产品类型 :
ELISA/assay
产品名称 :
IL-17AF酶联免疫吸附测定
目录 :
61-IAFHU-E01
规格 :
96 Wells
价格 :
700.00美元
更多信息或购买 :
ALPCO 产品网页
产品信息
目录号 :
61-IAFHU-E01
产品名称 :
IL-17AF酶联免疫吸附测定
标价 :
700.00美元
描述 :
IL-17A and IL-17F are members of the IL-17 family and signature Th17 cytokines. Of the six IL-17 family members, IL-17F and IL-17A share the strongest homology (50% amino acid identity) and the two genes are located in the same chromosomal region. Although both IL-17A and IL- 17F were originally found to be produced as disulfide-linked homodimers, recent studies have confirmed the production of IL-17AF heterodimers in in vitro-differentiated and polarized Th17 cells. Activated human CD4+ T cells in culture were found to secrete the IL-17F homodimer at 10-fold higher levels than the IL-17A homodimer, suggesting that the majority of the IL-17A protein expressed exists in the form of the IL-17AF heterodimer. Studies of Th17-polarized mouse splenocytes also indicate that the majority of IL-17 produced is complexed as the IL-17AF heterodimer. IL-17F and IL-17A have been observed in tissue samples from various autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, psoriasis, inflammatory bowel disease, and asthma.
Therapeutic Areas :
免疫学
物种 :
人类
样品类型 :
细胞培养, 柠檬酸盐血浆, 肝素血浆, 血清
规格 :
96 Wells
政府监管状态 :
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution :
Available Worldwide
应用 :
Immunoassays
样品尺寸 :
50微升
范围 :
31.3 - 2,000 pg/mL
敏感性 :
8.8 pg/mL
培养时间 :
3hr 30min
更多信息或购买 :
ALPCO 产品网页
公司信息
ALPCO
26G Keewaydin Drive
Salem, NH 03079
cs@alpco.com
www.alpco.com
1-800-592-5726 603-893-8914
公司总部: 美国
ALPCO成立于1990年，专注于高质量免疫研究用试剂盒的进口销售事业。自成立之日起，ALPCO的首要目标是为客户提供多种多样的检测产品线，并提供卓越的客户服务和技术支持。