ELISA/assay

Monkey IL-6 ELISA

61-IL6MK-E01

96 Wells

700.00美元

Monkey IL-6 ELISA

700.00美元

Interleukin-6 (IL-6) is a multi-functional cytokine that regulates immune responses, acute phase reactions and hematopoiesis and may play a central role in host defense mechanisms. IL-6 is usually not produced constitutively by normal cells, but its expression is readily induced by a variety of cytokines,lipopolysaccharide (LPS) or viral infections. IL-6 is a pleiotropic cytokine produced by a variety of cells. It acts on a wide range of tissues, exerting growth-induction, growth-inhibition, and differentiation respectively, depending on the nature of the target cells. IL-6 is involved in: . - the induction of B-cell differentiation . - the induction of acute phase proteins in liver cells . - growth promotion of myeloma/plasmacytoma/hybridoma cells . - induction of IL-2 and IL-2 receptor expression . - proliferation and differentiation of T cells . - inhibition of cell growth of certain myeloid leukemic cell lines and induction of their differentiation to macrophages . - enhancement of IL-3-induced multipotential colony cell formation in hematopoietic stem cells and induction of maturation of megakaryocytes as a thrombopoietic factor . - induction of mesangial cell growth . - induction of neural differentiation of PC 12 cells . - induction of keratinocyte growth . The abnormal production of IL-6 was first suggested to be related to polyclonal B-cell activation with autoantibody production in patients with cardiac myxoma. Since then, IL-6 has been suggested to be involved in the pathogenesis of a variety of diseases. Measurement of IL-6 levels in serum and other body fluids thus provides more detailed insights into various pathological situations.

Bone Metabolism, Diabetes & Obesity, Immunology

Non-Human Primate

细胞培养, 血清

96 Wells

Research Use Only. Not for Use in Diagnostic Procedures.

Available Worldwide

Immunoassays

50微升

1.9-120 U/毫升

1.3 U/毫升

3hr 10min