产品简要
公司名称 :
ALPCO
产品类型 :
ELISA/assay
产品名称 :
IL-8酶联免疫吸附测定
目录 :
61-IL8HU-E01
规格 :
96 Wells
价格 :
700.00美元
更多信息或购买 :
产品信息
目录号 :
61-IL8HU-E01
产品名称 :
IL-8酶联免疫吸附测定
标价 :
700.00美元
描述 :
Interleukin-8 selectively stimulates the ability of neutrophils and T-lymphocytes to invade injured or inflamed tissue. IL-8 also known as CXCL8 that is purified from peripheral blood monocytes is a 10 kDa protein showing at least 4 variant forms (77, 72, 70, and 69 amino acids, respectively) which differ in the length of the N-terminal and readily form dimers in solution. Two cystin-bridges are essential for the biological activity of IL-8. . Exogenous stimuli like LPS, but also IL-1, TNF-alpha and TNF-beta induce the secretion of IL-8 in a variety of different cell types including monocytes, endothelial and epithelial cells, peripheral blood mononuclear cells, dermal fibroblasts, keratinocytes, neutrophils, hepatocytes, synovial cells, and T-lymphocytes. The activities of IL-8 are not species-specific. Human IL-8 is also active in rodent and rabbit cells and differs from all other cytokines in its ability to specifically activate neutrophil granulocytes. This chemokine activates multiple intracellular signaling pathways downstream of two cell-surface, G protein-coupled receptors (CXCR1 and CXCR2). The property of IL-8 to stimulate movement of neutrophils across endothelial monolayers in vitro supports the concept of a central role for this molecule in the accumulation of neutrophils at inflammatory lesions in vivo.
Therapeutic Areas :
Diabetes & Obesity, Immunology
物种 :
人类
样品类型 :
细胞培养, 乙二胺四乙酸血浆, 肝素血浆, 血清
规格 :
96 Wells
政府监管状态 :
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution :
Available Worldwide
应用 :
Immunoassays
样品尺寸 :
50微升
范围 :
15.6 - 1,000 pg/mL
敏感性 :
2.0 pg/mL
培养时间 :
3hr 10min
更多信息或购买 :
公司信息
ALPCO
26G Keewaydin Drive
Salem, NH 03079
cs@alpco.com
www.alpco.com
1-800-592-5726 603-893-8914
公司总部: 美国
ALPCO成立于1990年,专注于高质量免疫研究用试剂盒的进口销售事业。自成立之日起,ALPCO的首要目标是为客户提供多种多样的检测产品线,并提供卓越的客户服务和技术支持。