产品简要
公司名称 :
ALPCO
产品类型 :
ELISA/assay
产品名称 :
Monkey TNF-alpha ELISA
目录 :
61-TNAMK-E01
规格 :
96 Wells
价格 :
700.00美元
更多信息或购买 :
产品信息
目录号 :
61-TNAMK-E01
产品名称 :
Monkey TNF-alpha ELISA
标价 :
700.00美元
描述 :
Tumor Necrosis Factor is a polypeptide cytokine produced by monocytes and macrophages. It functions as a multipotent modulator of immune response and further acts as a potent pyrogen. TNF-alpha circulates throughout the body responding to stimuli (infectious agents or tissue injury), activating neutrophils, altering the properties of vascular endothelial cells, regulating metabolic activities of other tissues, as well as exhibiting tumoricidal activity by inducing localized blood clotting. TNF-alpha also inhibits lipoprotein lipase activity resulting in cachexia, a physical wasting condition. Activation of B-cells by the Epstein Barr virus can be inhibited by TNF-alpha. Due to its varied actions throughout the immune system, TNF-alpha may play a role in the pathogenesis of many disease states. TNF-alpha production is mediated by the action of lymphokines and endotoxins on the macrophage. Purified monocytes produce TNF-alpha within four hours of stimulation by recombinant IL-2 and there is some in vitro evidence to suggest that TNF-alpha is expressed at high levels and with prolonged kinetics in T cells stimulated by both CD2 and CD28. Secretion of TNF-alpha is enhanced by gamma interferon. TNF then induces or enhances the specific production of Class I MHC antigen, GM-CSF, and IL-1.
Therapeutic Areas :
Diabetes & Obesity, Immunology
物种 :
Non-Human Primate
样品类型 :
细胞培养, 血清
规格 :
96 Wells
政府监管状态 :
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution :
Available Worldwide
应用 :
Immunoassays
样品尺寸 :
50微升
范围 :
28.1 - 1, 800 U/毫升
敏感性 :
6.0 U/毫升
培养时间 :
3hr 10min
更多信息或购买 :
公司信息
ALPCO
26G Keewaydin Drive
Salem, NH 03079
cs@alpco.com
www.alpco.com
1-800-592-5726 603-893-8914
公司总部: 美国
ALPCO成立于1990年,专注于高质量免疫研究用试剂盒的进口销售事业。自成立之日起,ALPCO的首要目标是为客户提供多种多样的检测产品线,并提供卓越的客户服务和技术支持。