抗体

磷酸甘油醛脱氢酶抗体

ATGA0394

100微升/50微升

290/170美元

单克隆

小鼠

nonconjugated

AT4E8

免疫印迹, 酶联免疫吸附测定, 免疫细胞化学

磷酸甘油醛脱氢酶抗体

一抗

290/170美元

单克隆

小鼠

AT4E8

未共轭

小鼠IgG2b, k

Multiple roles for glyceraldehyde-3-phosphate dehydrogenase (GAPDH) have been recently appreciated. GAPDH is found in the particulate fractions, such as the nucleus, the mitochondria, and the small vesicular fractions. GAPDH gene expression is specifically increased during programmed neuronal cell death. When cells are exposed to various stressors, dynamic subcellular re-distribution of GAPDH occurs. GAPDH is also involved in various diseases, especially neurodegenerative disorders and cancers. As a membrane protein, GAPDH functions in endocytosis; in the cytoplasm, it is involved in the translational control of gene expression; in the nucleus, it functions in nuclear tRNA export, in DNA replication, and in DNA repair.

人类

人类

未共轭

磷酸甘油醛脱氢酶来自兔肌肉

By protein-A affinity chromatography

Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.

100微升/50微升

1毫克/毫升

The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

酶联免疫吸附测定, 免疫印迹, 免疫细胞化学/IF

可以储存在+4C。 为长期储存, 分成小份儿保存在-20C。 避免反复冻融

Chuang DM., et al, (2005) Annu Rev Pharmacol Toxicol. 45:269-90. ; Mazzola JL., et al, (2002) Neurotoxicology. 23(4-5):603-9. ; Sirover MA. (1997) J Cell Biochem. 66(2):133-40.