蛋白

Tau, 1-352aa, Human, His tag, E.coli

ATGP0646

250微克/50微克

960/320美元

Tau, 1-352aa, Human, His tag, E.coli

蛋白

960/320美元

MAPT, also known as TAu, is a neuronal microtubule associated protein found predominantly on axons. The function of this protein is to promote tubulin polymerisation and stabilise microtubules, but it also serves to link certain signalling pathways to the cytoskeleton. MAPT, in its hyperphosphorylated form, is the major component of paired helical filaments (PHF) and neurofibrillary lesions in Alzheimer's disease (AD) brain. Recombinant human MAPT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques

人类

Microtubule-associated protein tau, TAu, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, Microtubule-associated protein tau

> 85% by SDS - PAGE

Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M Nacl, 1mM DTT, 10% glycerol

250微克/50微克

0.5毫克/毫升(由布拉德福德Bradford检测确定)

可以储存在+4C短期(1-2周)。 为长期储存, 分成小份儿保存在-20C或-70C。 避免反复冻融

Jack CR Jr., et al. (2010) Lancet Neurol. 9(1):119-28.; Buescher JL., et al. (2010) J Biol Chem. 285(11):7957-63.;

NP_058525